Jackson Laboratory faculty investigate the basic processes that take us from fertilized egg to functional being, which also hold key information about how our genes function.
Coordinated, proper hair cell orientation is vital for both hearing and motion detection, because each cell only detects motion in one direction. But how is that achieved? Basile Tarchini reveals the complex molecular cascade that yields proper hair cell arrangement in a new paper in Nature Communications.
Hilde Mangold was born October 20, 1898. She was a German embryologist who was best known for her 1923 dissertation which was the foundation for her mentor, Hans Spemann's, 1935 Nobel Prize in Physiology or Medicine for the discovery of the embryonic organizer.
A research team led by Basile Tarchini has found two new proteins that are essential to the correct elongation of stereocilia, tiny hair-like cellular protrusions in the inner ear.
Work by a team including JAX Assistant Professor Basile Tarchini, Ph.D., is shedding light on the mechanism that directs the assembly of the staircase pattern of the hair bundle.
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