Aamir Zuberi, Ph.D.
Director, Technology Evaluation and Development
Lead Scientist responsible for the development and validation of Mouse models associated with Clinically associated Rare and Orphan Diseases
Aamir graduated with a PhD in Microbial Molecular Genetics (University of Sheffield, UK) and has 25+ years of expertise in murine molecular genetics and 30+ years of expertise in molecular biology and genome manipulation. His postdoctoral training at the University of California, the University of Illinois and at the Jackson Laboratory focused on genetic regulation of transcription factors, posttranslational methylation associated with nutrient sensing, and the cloning and characterization of novel mouse genes regulating T cell mediated transplantation rejection. He was an NIH-funded Assistant Professor at Louisiana State University and Core Director of a Murine Metabolic Phenotyping Core for over 10 years investigating how natural genetic variation between mouse strains impacts dietary preference, metabolism and insulin resistance and the role of dietary supplements in regulating these interactions. He has coauthored 51 publications to date, organized and chaired scientific sessions of international meetings and served on the mammalian gene nomenclature and the mouse Chromosome 2 committees. Since returning to the Jackson Laboratory, Aamir has developed and leads the Rare and Orphan Disease mouse model development portfolio and managed the completion of over 200 new mouse models in the last five years using CRISPR/Cas9, Embryonic stem cell and transgenic strategies.
Education and experience
Education
Ph.D. (Molecular Genetics), University of Sheffield, U.K
B.Sc. (Double Major in Microbiology & Biochemistry), University of London, U.K
Experience
- Technology and Resource Development Scientist, The Jackson Laboratory, Bar Harbor, ME; 1 year
- Process Improvement Program Manager, The Jackson Laboratory, Bar Harbor, ME; 2 years
- Assistant Professor. Functional Genomics laboratory Pennington Biomedical Research Center - LSU, Baton Rouge, LA; 12 years
- Director of the Animal/Preclinical Research Core of the Botanical Research Center, Pennington Biomedical Research Center - LSU, Baton Rouge, LA; 5 years
- Postdoctoral Research Associate, The Jackson Laboratory, Bar Harbor ME; 6 years
- Postdoctoral training
- The Jackson Laboratory, Bar Harbor, ME, 3 years
- University of Illinois, Champaign-Urbana (Biochemistry), 3 years
- University of California, Davis (Biochemistry and Biophysics); 2 years
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Research HighlightMarch 14, 2023Grant supports development of peroxisome mouse models
New $3 million NIH grant will establish a Mouse Mutant Peroxisome Research Resource.
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Press ReleaseNovember 23, 2020New SETBP1 rare disease models developed by JAX
JAX has recently developed two new genetic mouse models to be used in SETBP1 rare disease research.