I am fascinated by the biology of the immune system, particularly innate cells, in physiological or pathological contexts. The immunoglobulin superfamily orchestrates this biology and holds great promise in our understanding of it and perhaps harnessing it therapeutically.
My previous work has had a focus on myeloid cells and how they themselves or in shaping acquired immunity affect progression of primary and metastatic tumor lesions. My work here focuses on members of the immunoglobulin superfamily, and trying to understand the central role they play through a comprehensive view of tumor immunity, autoimmunity and viral infection. I am particularly interested in using powerful genetic approaches, from conditional knockouts, lineage tracing to sequencing analyses, to study the roles of these molecules.
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