Familial AD Models

MODEL JAX # DESCRIPTION NOMENCLATURE REFERENCE
APPSAA 34711 Humanized Ab sequence with Swedish, Arctic and Austrian mutations B6.Cg-Apptm1.1Dnli/J PMID:35690868
APPSDI 37453 Humanized Ab sequence with Swedish, Dutch and Iowa mutations B6.Cg-Appem7(hAbeta,SDI)Msasn/Msasn
APPSFL 37454 Humanized Ab sequence with Swedish, Florida and London mutations B6.Cg-Appem8(hAbeta,SFL)Msasn/Msasn
APOE4/APPSAA 39775 Humanized Ab sequence with Swedish, Arctic and Austrian mutations; humanized APOE4 B6.Cg-Apptm1.1DnliApoetm1.1(APOE*4)Adiuj/MSasnJ