We use cookies to personalize our website and to analyze web traffic to improve the user experience. You may decline these cookies although certain areas of the site may not function without them. Please refer to our privacy policy for more information.

Settings

Save and close

JAX Frontend Platform

Give

MAPT (TAU) Models

MODEL JAX # TYPE DESCRIPTION SOURCE NOMENCLATURE
MAPT(H1.0)-GR 35398 Genome replacement 190kB human construct of H1 haplotype replacing mouse Mapt Koob B6J.B6N-Tc(HSA17)2Mdk/J
MAPT(H2.1)-GR 33668 Genome replacement 190kB human construct of H2 haplotype replacing mouse Mapt Koob B6J.B6N(CBA)-Tc(HSA17)1Mdk/J
MAPT(H1.0*)P301L-GR 37420 Genome replacement 190kB human construct of H1 haplotype with P301L variant replacing mouse Mapt Koob B6J.B6N-Tc(HSA17*P301L)1Mdk/J
MAPT(H1.0*N279K)-GR 35794 Genome replacement 190kB human construct of H1 haplotype with N279K risk variant replacing mouse Mapt Koob B6J.B6N(Cg)-Tc(HSA17*N279K)1Mdk/J
MAPT 10IVS+16 C>T 36664 Genome replacement 190kB human construct of H1 haplotype with non-coding C to T (rs63751011) mutation in intron 10 replacing mouse Mapt Koob B6(Cg)-Tc(HSA17*)1Mdk/J
Leading the search for tomorrow's cures

©2025 The Jackson Laboratory