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MODEL | JAX # | TYPE | DESCRIPTION | SOURCE | NOMENCLATURE |
---|---|---|---|---|---|
MAPT(H1.0)-GR | 35398 | Genome replacement | 190kB human construct of H1 haplotype replacing mouse Mapt | Koob | B6J.B6N-Tc(HSA17)2Mdk/J |
MAPT(H2.1)-GR | 33668 | Genome replacement | 190kB human construct of H2 haplotype replacing mouse Mapt | Koob | B6J.B6N(CBA)-Tc(HSA17)1Mdk/J |
MAPT(H1.0*)P301L-GR | 37420 | Genome replacement | 190kB human construct of H1 haplotype with P301L variant replacing mouse Mapt | Koob | B6J.B6N-Tc(HSA17*P301L)1Mdk/J |
MAPT(H1.0*N279K)-GR | 35794 | Genome replacement | 190kB human construct of H1 haplotype with N279K risk variant replacing mouse Mapt | Koob | B6J.B6N(Cg)-Tc(HSA17*N279K)1Mdk/J |
MAPT 10IVS+16 C>T | 36664 | Genome replacement | 190kB human construct of H1 haplotype with non-coding C to T (rs63751011) mutation in intron 10 replacing mouse Mapt | Koob | B6(Cg)-Tc(HSA17*)1Mdk/J |