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JAX Frontend Platform

MAPT (TAU) Models

MODEL JAX # TYPE DESCRIPTION SOURCE NOMENCLATURE
MAPT(H1.0)-GR 35398 Genome replacement 190kB human construct of H1 haplotype replacing mouse Mapt Koob B6J.B6N-Tc(HSA17)2Mdk/J
MAPT(H2.1)-GR 33668 Genome replacement 190kB human construct of H2 haplotype replacing mouse Mapt Koob B6J.B6N(CBA)-Tc(HSA17)1Mdk/J
MAPT(H1.0*)P301L-GR 37420 Genome replacement 190kB human construct of H1 haplotype with P301L variant replacing mouse Mapt Koob B6J.B6N-Tc(HSA17*P301L)1Mdk/J
MAPT(H1.0*N279K)-GR 35794 Genome replacement 190kB human construct of H1 haplotype with N279K risk variant replacing mouse Mapt Koob B6J.B6N(Cg)-Tc(HSA17*N279K)1Mdk/J
MAPT 10IVS+16 C>T 36664 Genome replacement 190kB human construct of H1 haplotype with non-coding C to T (rs63751011) mutation in intron 10 replacing mouse Mapt Koob B6(Cg)-Tc(HSA17*)1Mdk/J

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