| MODEL |
JAX # |
TYPE |
DESCRIPTION |
SOURCE |
NOMENCLATURE |
| MAPT(H1.0)-GR |
35398 |
Genome replacement |
190kB human construct of H1 haplotype replacing mouse Mapt |
Koob |
B6J.B6N-Tc(HSA17)2Mdk/J |
| MAPT(H2.1)-GR |
33668 |
Genome replacement |
190kB human construct of H2 haplotype replacing mouse Mapt |
Koob |
B6J.B6N(CBA)-Tc(HSA17)1Mdk/J |
| MAPT(H1.0*)P301L-GR |
37420 |
Genome replacement |
190kB human construct of H1 haplotype with P301L variant replacing mouse Mapt |
Koob |
B6J.B6N-Tc(HSA17*P301L)1Mdk/J |
| MAPT(H1.0*N279K)-GR |
35794 |
Genome replacement |
190kB human construct of H1 haplotype with N279K risk variant replacing mouse Mapt |
Koob |
B6J.B6N(Cg)-Tc(HSA17*N279K)1Mdk/J |
| MAPT 10IVS+16 C>T |
36664 |
Genome replacement |
190kB human construct of H1 haplotype with non-coding C to T (rs63751011) mutation in intron 10 replacing mouse Mapt |
Koob |
B6(Cg)-Tc(HSA17*)1Mdk/J |