The massive expansion of biological data collections in the last 20 years alongside dramatic developments in artificial intelligence has created an unprecedented opportunity for using data to integrate human and mammalian model research, unlock biological insights, and empower the biomedical community worldwide. To meet this challenge, JAX Data Science brings together scientists, software engineers and other skilled personnel while also building local, national and international partnerships that will allow researchers to integrate their data, tools and discoveries, amplifying the impact of these collective contributions.