Preclinical Research Services

We develop innovative preclinical models and services that enable informed decision making and compound evaluation during in vivo research. De-risk drug development and move your therapeutic into the clinic faster.

JAX Preclinical Services offers the most translational and predictive efficacy, pharmacokinetics (PK) and safety testing for therapeutics such as monoclonal antibodies, bispecifics, CAR-T, antibody-drug conjugates, and combination therapies.

By combining genetically defined tumors with innovative humanized mouse models, JAX enables the validation of therapeutic candidates in an array of in vivo research that better recapitulate the human condition.

Neurobiology

Learn about the ways in which JAX can support your research in the areas of neurodegenerative, neuromuscular, and neurodevelopmental disorders. JAX offers tailored models and efficacy studies for your preclinical research.

Oncology

Discover JAX's Oncology models and efficacy studies. Evaluate your CAR or Antibody based therapeutics using JAX's cutting-edge immune-humanized mice featuring characterized PDX tumors.

Immuno-Oncology

Analyze the human immune and tumor environment to assess the efficacy of your therapeutic through a safety or pharmacokinetic in vivo study using a mouse model with a humanized immune system. 

Immunology

Assess therapeutic antibodies and compounds, which include preclinical studies on GvHD using immune humanized mouse models incorporating CD34+ and PBMC donors.

Autoimmune

Conduct tailored efficacy studies for assessing new and established therapeutic compounds for various autoimmune disorders, including Lupus, Type 1 Diabetes, and Psoriasis.

Rare Disease

JAX offers the world's largest collection of spontaneous, targeted, and transgenic mutant mouse strains, hundreds of which model rare diseases, for preclinical research.

Metabolic

Selecting the appropriate model is crucial for metabolic research. Discover the ideal model for your research needs from JAX's extensive selection of diabetes and obesity mouse models. Our collection includes a variety of NASH models and diet-induced models to enhance your in vivo study.

Antibody Evaluation

Our FcRn models provide reliable data for expediting the development of therapeutic candidates for clinical trials. Our approach offers a viable and established option in place of using non-human primates. These in vivo studies can assess various therapeutic candidates containing Fc-domains or albumin.

Advisory & Consulting

Gain insight from JAX’s experience in vivarium operations, mouse genetics, breeding, husbandry, surgical techniques, and more. With an assessment of your specific preclinical research needs, JAX can provide guidance on recommended studies or institutional approaches, as well as support in their implementation.

Preclinical Research Services

How We Meet Your Preclinical Research Needs

Find Your Model

Define Your In Vivo Study

Get Your Data

Clinical Research Therapeutic Areas

Neurobiology

Oncology

Immuno-Oncology

Immunology

Autoimmune

Rare Disease

Metabolic

Antibody Evaluation

Advisory & Consulting

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Immune Humanized Mice

JAX Mice Search

Why JAX Mice

Immunodeficient Portfolio

Cytokine Release Syndrome Evaluation

Learn More About Preclinical Drug Development After In Vivo Research

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