The Global COVID-19 Pandemic
Coronavirus disease (COVID-19) is an infectious disease caused by a novel member of the coronavirus family of viruses. Since Covid-19 was declared a global pandemic on March 11, 2020, millions of cases of have been documented in 192 countries and regions worldwide (Johns Hopkins University; World Health Organization)
About this Site: Coronavirus Research using the Laboratory Mouse
The laboratory mouse is an important preclinical model for studying coronavirus biology and treatment approaches. The information on this site summarizes information about mouse strains and genes relevant to the study of coronavirus infection and pathology. This information has been expertly curated from pre-prints and peer-reviewed publications dating back to the 1980s by biocuration scientists from the Mouse Genome Informatics (MGI) knowledgebase hosted at The Jackson Laboratory.
See all curated publications that report on mouse models and genes related to coronaviruses in MGI.
Mouse Strains Used in Coronavirus Research
1-strain | 2-mgi | 3-attrs | 4-geno-mgi | 5-allele | 6-allele-mgi | 7-type | 8-subtypes | 9-do-term | 10-do-id | 11-mp-term | 12-mp-id | 13-cite | 14-jnum | 15-tags | Strain | Genotype Details | Human Disease and Mouse Phenotype Categories | References | Keywords |
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129-Ifngr1tm1Agt/J | MGI:2165098 | mutant strain|targeted mutation | MGI:6403197 | Ifngr1tm1Agt | MGI:1857286 | Targeted | Null/knockout | immune system | MP:0005387 | Frieman MB, PLoS Pathog 2010 Apr 8;6(4):e1000849 | J:286237 | Pathology|SARS-CoV-MA_virus | 129-Ifngr1tm1Agt/Jmutant strain|targeted mutation |
MGI:6403197 | immune system |
Frieman MB, PLoS Pathog 2010 Apr 8;6(4):e1000849 |
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129S1/SvImJ | MGI:3037980 | inbred strain | MGI:3582226 | behavior/neurological immune system | MP:0005386 MP:0005387 | Gralinski LE, PLoS Genet 2015 Oct;11(10):e1005504 Josset L, RNA Biol 2014;11(7):875-90 Peng X, mBio 2010 Oct 26;1(5): Peng X, mBio 2011;2(6): Xiong H, G3 (Bethesda) 2014 Jun 5;4(8):1429-44 | J:268979 J:276026 J:276986 J:276989 J:276183 | Infection|SARS-CoV-MA_virus SARS-CoV-MA_virus | 129S1/SvImJinbred strain |
MGI:3582226 | behavior/neurological immune system |
Gralinski LE, PLoS Genet 2015 Oct;11(10):e1005504 Josset L, RNA Biol 2014;11(7):875-90 Peng X, mBio 2010 Oct 26;1(5): Peng X, mBio 2011;2(6): Xiong H, G3 (Bethesda) 2014 Jun 5;4(8):1429-44 |
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(129S1/SvImJ x B6.Cg-Tg(K18-ACE2)2Prlmn/J)F1/J | MGI:6865672 | F1 hybrid|mutant strain|transgenic | Robertson SJ, Nat Commun 2023 Jul 25;14(1):4481 | J:338561 | Infection|SARS-CoV-2_virus | (129S1/SvImJ x B6.Cg-Tg(K18-ACE2)2Prlmn/J)F1/JF1 hybrid|mutant strain|transgenic |
Robertson SJ, Nat Commun 2023 Jul 25;14(1):4481 |
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129S2/SvPasCrl | MGI:3587894 | inbred strain | Walls AC, Cell Rep 2022 Aug 30;40(9):111299 Ying B, bioRxiv 2022 Feb;(): Ying B, Sci Transl Med 2022 Feb 2;14(630):eabm3302 | J:328107 J:321873 J:336008 | SARS-CoV-2_virus|Vaccine|Variant|VOC_B.1.351_Beta Vaccine|VOC_B.1.1.529_Omicron SARS-CoV-2-MA_virus|SARS-CoV-2_virus|Vaccine|VOC_B.1.1.7_Alpha|VOC_B.1.351_Beta|VOC_B.1.617.2_Delta | 129S2/SvPasCrlinbred strain |
Walls AC, Cell Rep 2022 Aug 30;40(9):111299 Ying B, bioRxiv 2022 Feb;(): Ying B, Sci Transl Med 2022 Feb 2;14(630):eabm3302 |
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129S6/SvEv-Stat1tm1Rds/Tac | MGI:3771555 | mutant strain|targeted mutation | MGI:3771372 | Stat1tm1Rds | MGI:1861949 | Targeted | Null/knockout | breast cancer severe acute respiratory syndrome | DOID:1612 DOID:2945 | cardiovascular system cellular digestive/alimentary system endocrine/exocrine glands hematopoietic system homeostasis/metabolism immune system integument liver/biliary system muscle nervous system respiratory system skeleton neoplasm mortality/aging | MP:0005385 MP:0005384 MP:0005381 MP:0005379 MP:0005397 MP:0005376 MP:0005387 MP:0010771 MP:0005370 MP:0005369 MP:0003631 MP:0005388 MP:0005390 MP:0002006 MP:0010768 | Frieman MB, PLoS Pathog 2010 Apr 8;6(4):e1000849 | J:286237 | Pathology|SARS-CoV-MA_virus | 129S6/SvEv-Stat1tm1Rds/Tacmutant strain|targeted mutation |
MGI:3771372 | cardiovascular system cellular digestive/alimentary system endocrine/exocrine glands hematopoietic system homeostasis/metabolism immune system integument liver/biliary system muscle nervous system respiratory system skeleton neoplasm mortality/aging breast cancer severe acute respiratory syndrome |
Frieman MB, PLoS Pathog 2010 Apr 8;6(4):e1000849 |
129S6/SvEvTac | MGI:3044417 | inbred strain | Roberts A, Virus Res 2008 Apr;133(1):20-32 Subbarao K, Trends Microbiol 2006 Jul;14(7):299-303 | J:286331 J:286332 | Infection|SARS-CoV_virus|Vaccine SARS-CoV_virus | 129S6/SvEvTacinbred strain |
Roberts A, Virus Res 2008 Apr;133(1):20-32 Subbarao K, Trends Microbiol 2006 Jul;14(7):299-303 |
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129X1/SvJ | MGI:3044210 | inbred strain | Okumura A, J Virol 1996 Jun;70(6):4146-9 | J:52540 | Mouse_Hepatitis_virus | 129X1/SvJinbred strain |
Okumura A, J Virol 1996 Jun;70(6):4146-9 |
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A/J | MGI:2159747 | inbred strain | MGI:3807714 | Coronavirus infectious disease | DOID:0080599 | hearing/vestibular/ear hematopoietic system immune system nervous system | MP:0005377 MP:0005397 MP:0005387 MP:0003631 | Dangi T, bioRxiv 2021 Jun;(): De Albuquerque N, J Virol 2006 Nov;80(21):10382-94 Gralinski LE, PLoS Genet 2015 Oct;11(10):e1005504 Josset L, RNA Biol 2014;11(7):875-90 Khanolkar A, J Immunol 2010 Jul 15;185(2):1132-41 Lee M, bioRxiv 2020 Dec;(): Lucchiari MA, J Gen Virol 1991 Jun;72(Pt 6):1317-22 Tian J, bioRxiv 2020;(): Tian J, bioRxiv 2021 Feb;(): Wang GZ, bioRxiv 2020;(): Wang Y, Invest Ophthalmol Vis Sci 1996 Jan;37(1):250-4 Xiong H, G3 (Bethesda) 2014 Jun 5;4(8):1429-44 | J:308670 J:288204 J:268979 J:276026 J:161935 J:299101 J:27269 J:295388 J:302152 J:296066 J:36900 J:276183 | SARS-CoV-2_virus|SARS-CoV_virus|Vaccine Mouse_Hepatitis_virus|Pathology Infection|SARS-CoV-MA_virus SARS-CoV-MA_virus Mouse_Hepatitis_virus|SARS-CoV-2_virus Mouse_Hepatitis_virus Mouse_Hepatitis_virus|Treatment Comorbidity|SARS-CoV-2_virus | A/Jinbred strain |
MGI:3807714 | Coronavirus infectious disease hearing/vestibular/ear hematopoietic system immune system nervous system |
Dangi T, bioRxiv 2021 Jun;(): De Albuquerque N, J Virol 2006 Nov;80(21):10382-94 Gralinski LE, PLoS Genet 2015 Oct;11(10):e1005504 Josset L, RNA Biol 2014;11(7):875-90 Khanolkar A, J Immunol 2010 Jul 15;185(2):1132-41 Lee M, bioRxiv 2020 Dec;(): Lucchiari MA, J Gen Virol 1991 Jun;72(Pt 6):1317-22 Tian J, bioRxiv 2020;(): Tian J, bioRxiv 2021 Feb;(): Wang GZ, bioRxiv 2020;(): Wang Y, Invest Ophthalmol Vis Sci 1996 Jan;37(1):250-4 Xiong H, G3 (Bethesda) 2014 Jun 5;4(8):1429-44 |
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A/JCr | MGI:6156905 | inbred strain | Khanolkar A, J Virol 2009 Sep;83(17):8946-56 | J:153918 | Mouse_Hepatitis_virus|Pathology | A/JCrinbred strain |
Khanolkar A, J Virol 2009 Sep;83(17):8946-56 |
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(A/J x B6.Cg-Tg(K18-ACE2)2Prlmn/J)F1/J | MGI:6865666 | F1 hybrid|mutant strain|transgenic | Robertson SJ, Nat Commun 2023 Jul 25;14(1):4481 | J:338561 | Infection|SARS-CoV-2_virus | (A/J x B6.Cg-Tg(K18-ACE2)2Prlmn/J)F1/JF1 hybrid|mutant strain|transgenic |
Robertson SJ, Nat Commun 2023 Jul 25;14(1):4481 |
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Arc:ARC(S) | MGI:5306408 | outbred stock | Eldi P, bioRxiv 2021 Sep;(): | J:310113 | SARS-CoV-2_virus|Vaccine | Arc:ARC(S)outbred stock |
Eldi P, bioRxiv 2021 Sep;(): |
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B10.BR-H2k2 H2-T18a/SgSnJ | MGI:2386242 | congenic|major histocompatibility congenic|mutant strain | Khanolkar A, J Virol 2009 Sep;83(17):8946-56 | J:153918 | Mouse_Hepatitis_virus|Pathology | B10.BR-H2k2 H2-T18a/SgSnJcongenic|major histocompatibility congenic|mutant strain |
Khanolkar A, J Virol 2009 Sep;83(17):8946-56 |
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B10.D2-Hc0 H2d H2-T18c/oSnJ | MGI:2160070 | congenic|major histocompatibility congenic|mutant strain | Khanolkar A, J Virol 2009 Sep;83(17):8946-56 | J:153918 | Mouse_Hepatitis_virus|Pathology | B10.D2-Hc0 H2d H2-T18c/oSnJcongenic|major histocompatibility congenic|mutant strain |
Khanolkar A, J Virol 2009 Sep;83(17):8946-56 |
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B6.129(Cg)-Foxp3tm4(YFP/icre)Ayr/J | MGI:5306407 | congenic|mutant strain|targeted mutation | Harb H, Immunity 2021 Apr 22;(): | J:347529 | Infection | B6.129(Cg)-Foxp3tm4(YFP/icre)Ayr/Jcongenic|mutant strain|targeted mutation |
Harb H, Immunity 2021 Apr 22;(): |
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B6.129(Cg)-Wwtr1tm1.2Hmc/J | MGI:6285617 | congenic|mutant strain|targeted mutation | Harb H, Immunity 2021 Apr 22;(): | J:347529 | Infection | B6.129(Cg)-Wwtr1tm1.2Hmc/Jcongenic|mutant strain|targeted mutation |
Harb H, Immunity 2021 Apr 22;(): |
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B6.129-Ido1tm1Alm/J | MGI:3603213 | congenic|mutant strain|targeted mutation | McDermott JE, BMC Syst Biol 2016 Sep 23;10(1):93 | J:288523 | Pathology|SARS-CoV-MA_virus | B6.129-Ido1tm1Alm/Jcongenic|mutant strain|targeted mutation |
McDermott JE, BMC Syst Biol 2016 Sep 23;10(1):93 |
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B6.129P2-Ace2tm1Pngr/J | MGI:5912242 | congenic|mutant strain|targeted mutation | MGI:5912243 MGI:6402915 | Ace2tm1Pngr | MGI:2661723 | Targeted | Null/knockout | cardiovascular system immune system | MP:0005385 MP:0005387 | Kuba K, Nat Med 2005 Aug;11(8):875-9 | J:286299 | Infection|SARS-CoV_virus | B6.129P2-Ace2tm1Pngr/Jcongenic|mutant strain|targeted mutation |
MGI:5912243 MGI:6402915 | cardiovascular system immune system |
Kuba K, Nat Med 2005 Aug;11(8):875-9 |
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B6.129P2(C)-Cd19tm1(cre)Cgn/J | MGI:3710504 | congenic|mutant strain|targeted mutation | Luo Y, Signal Transduct Target Ther 2022 Jan 4;7(1):7 | J:333746 | SARS-CoV-2_virus|Vaccine | B6.129P2(C)-Cd19tm1(cre)Cgn/Jcongenic|mutant strain|targeted mutation |
Luo Y, Signal Transduct Target Ther 2022 Jan 4;7(1):7 |
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B6.129P2-Ccr2tm1Mae | MGI:3841132 | congenic|targeted mutation | MGI:3841005 | Ccr2tm1Mae | MGI:2158345 | Targeted | Null/knockout | age related macular degeneration Coronavirus infectious disease | DOID:10871 DOID:0080599 | behavior/neurological cardiovascular system hematopoietic system immune system nervous system pigmentation respiratory system vision/eye | MP:0005386 MP:0005385 MP:0005397 MP:0005387 MP:0003631 MP:0001186 MP:0005388 MP:0005391 | Sheahan T, PLoS Pathog 2008 Dec;4(12):e1000240 | J:162707 | Pathology|SARS-CoV-MA_virus | B6.129P2-Ccr2tm1Maecongenic|targeted mutation |
MGI:3841005 | behavior/neurological cardiovascular system hematopoietic system immune system nervous system pigmentation respiratory system vision/eye age related macular degeneration Coronavirus infectious disease |
Sheahan T, PLoS Pathog 2008 Dec;4(12):e1000240 |
B6.129P2-Ccr5tm1Kuz | MGI:4418878 | congenic|mutant strain|targeted mutation | MGI:4418655 | Ccr5tm1Kuz | MGI:1861911 | Targeted | Null/knockout | Coronavirus infectious disease | DOID:0080599 | behavior/neurological cardiovascular system immune system nervous system respiratory system vision/eye mortality/aging | MP:0005386 MP:0005385 MP:0005387 MP:0003631 MP:0005388 MP:0005391 MP:0010768 | Sheahan T, PLoS Pathog 2008 Dec;4(12):e1000240 | J:162707 | Pathology|SARS-CoV-MA_virus | B6.129P2-Ccr5tm1Kuzcongenic|mutant strain|targeted mutation |
MGI:4418655 | behavior/neurological cardiovascular system immune system nervous system respiratory system vision/eye mortality/aging Coronavirus infectious disease |
Sheahan T, PLoS Pathog 2008 Dec;4(12):e1000240 |
B6.129P2(Cg)-Yap1tm1.1Dupa/J | MGI:6259136 | congenic|mutant strain|targeted mutation | Harb H, Immunity 2021 Apr 22;(): | J:347529 | Infection | B6.129P2(Cg)-Yap1tm1.1Dupa/Jcongenic|mutant strain|targeted mutation |
Harb H, Immunity 2021 Apr 22;(): |
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B6.129P2-Cxcr3tm1Dgen/J | MGI:3604638 | congenic|mutant strain|targeted mutation | McDermott JE, BMC Syst Biol 2016 Sep 23;10(1):93 | J:288523 | Pathology|SARS-CoV-MA_virus | B6.129P2-Cxcr3tm1Dgen/Jcongenic|mutant strain|targeted mutation |
McDermott JE, BMC Syst Biol 2016 Sep 23;10(1):93 |
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B6.129P2-Cxcr6tm1Litt/J | MGI:3696273 | congenic|mutant strain|targeted mutation | Schafer A, mBio 2022 Aug 30;13(4):e0145422 | J:327836 | SARS-CoV-2-MA_virus|SARS-CoV-MA_virus | B6.129P2-Cxcr6tm1Litt/Jcongenic|mutant strain|targeted mutation |
Schafer A, mBio 2022 Aug 30;13(4):e0145422 |
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B6.129P2-Ighem1Rcas/J | MGI:6725129 | congenic|endonuclease-mediated mutation|mutant strain | Xu J, Nature 2021 Jun 7;(): | J:307753 | SARS-CoV-2_virus|Treatment|VOC_B.1.1.7_Alpha|VOC_B.1.351_Beta|VOC_P.1_Gamma | B6.129P2-Ighem1Rcas/Jcongenic|endonuclease-mediated mutation|mutant strain |
Xu J, Nature 2021 Jun 7;(): |
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B6.129P2-Lyz2tm1(cre)Ifo/J | MGI:2680712 | congenic|mutant strain|targeted mutation | Musiu C, Cell Death Differ 2021 Sep 13;(): | J:313338 | Pathology|SARS-CoV-2_virus | B6.129P2-Lyz2tm1(cre)Ifo/Jcongenic|mutant strain|targeted mutation |
Musiu C, Cell Death Differ 2021 Sep 13;(): |
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B6.129P2-Myd88tm1Aki | MGI:3697090 | congenic|mutant strain|targeted mutation | MGI:3577712 | Myd88tm1Aki | MGI:2385681 | Targeted | Null/knockout | Coronavirus infectious disease | DOID:0080599 | cardiovascular system cellular digestive/alimentary system hearing/vestibular/ear hematopoietic system homeostasis/metabolism immune system nervous system renal/urinary system respiratory system mortality/aging | MP:0005385 MP:0005384 MP:0005381 MP:0005377 MP:0005397 MP:0005376 MP:0005387 MP:0003631 MP:0005367 MP:0005388 MP:0010768 | Sheahan T, PLoS Pathog 2008 Dec;4(12):e1000240 | J:162707 | Pathology|SARS-CoV-MA_virus | B6.129P2-Myd88tm1Akicongenic|mutant strain|targeted mutation |
MGI:3577712 | cardiovascular system cellular digestive/alimentary system hearing/vestibular/ear hematopoietic system homeostasis/metabolism immune system nervous system renal/urinary system respiratory system mortality/aging Coronavirus infectious disease |
Sheahan T, PLoS Pathog 2008 Dec;4(12):e1000240 |
B6.129P2-Nos2tm1Lau/J | MGI:2163101 | congenic|mutant strain|targeted mutation | Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 | J:296686 | Pathology|SARS-CoV-2_virus|Treatment | B6.129P2-Nos2tm1Lau/Jcongenic|mutant strain|targeted mutation |
Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 |
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B6.129P2-Rbpjtm1Hon/HonRbrc | MGI:3761296 | congenic|mutant strain|targeted mutation | Harb H, Immunity 2021 Apr 22;(): | J:347529 | Infection | B6.129P2-Rbpjtm1Hon/HonRbrccongenic|mutant strain|targeted mutation |
Harb H, Immunity 2021 Apr 22;(): |
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B6.129P2-Sirpatm1Nog/Rbrc | MGI:3763171 | congenic|mutant strain|targeted mutation | Wenzek C, iScience 2022 Dec 22;25(12):105540 | J:331693 | SARS-CoV-2_virus | B6.129P2-Sirpatm1Nog/Rbrccongenic|mutant strain|targeted mutation |
Wenzek C, iScience 2022 Dec 22;25(12):105540 |
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B6.129P2(SJL)-Myd88tm1.1Defr | MGI:6272303 | congenic|mutant strain|targeted mutation | MGI:6272304 | Myd88tm1.1Defr | MGI:4421295 | Targeted | Null/knockout | behavior/neurological hematopoietic system immune system nervous system mortality/aging | MP:0005386 MP:0005397 MP:0005387 MP:0003631 MP:0010768 | Butchi N, J Virol 2015 Sep 15;89(18):9299-312 | J:224849 | Infection|Mouse_Hepatitis_virus|Pathology | B6.129P2(SJL)-Myd88tm1.1Defrcongenic|mutant strain|targeted mutation |
MGI:6272304 | behavior/neurological hematopoietic system immune system nervous system mortality/aging |
Butchi N, J Virol 2015 Sep 15;89(18):9299-312 |
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B6.129S2-Cd8atm1Mak/J | MGI:2163961 | congenic|mutant strain|targeted mutation | Yang J, Nature 2020 Jul 29;(): | J:292665 | SARS-CoV-2_virus|Vaccine | B6.129S2-Cd8atm1Mak/Jcongenic|mutant strain|targeted mutation |
Yang J, Nature 2020 Jul 29;(): |
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B6.129S2(Cg)-Ace2tm1(ACE2)Dwnt/J | MGI:6469882 | congenic|mutant strain|targeted mutation | Tada T, Proc Natl Acad Sci U S A 2023 Jun 6;120(23):e2303509120 Winkler ES, J Virol 2022 Jan 12;96(1):e0151121 Zhou B, Nature 2021 Apr;592(7852):122-127 | J:338414 J:331773 J:305777 | SARS-CoV-2_virus|Treatment|VOC_B.1.1.529_Omicron Infection|SARS-CoV-2_virus|VOC_B.1.1.7_Alpha|VOC_B.1.351_Beta Infection|SARS-CoV-2_virus | B6.129S2(Cg)-Ace2tm1(ACE2)Dwnt/Jcongenic|mutant strain|targeted mutation |
Tada T, Proc Natl Acad Sci U S A 2023 Jun 6;120(23):e2303509120 Winkler ES, J Virol 2022 Jan 12;96(1):e0151121 Zhou B, Nature 2021 Apr;592(7852):122-127 |
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B6.129S2-Ciitatm1Ccum/J | MGI:2164648 | congenic|mutant strain|targeted mutation | Chen JS, bioRxiv 2021 Jun;(): | J:308655 | SARS-CoV-2_virus|VOC_B.1.351_Beta | B6.129S2-Ciitatm1Ccum/Jcongenic|mutant strain|targeted mutation |
Chen JS, bioRxiv 2021 Jun;(): |
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B6.129S2-Ifnar1tm1Agt/Mmjax | MGI:4836218 | congenic|mutant strain|targeted mutation | Hassert M, PLoS Pathog 2020 Dec;16(12):e1009163 Ngo VL, Cell Host Microbe 2024 Jan 23;(): | J:319459 J:345954 | Infection|SARS-CoV-2_virus Infection|MERS-CoV-MA_virus | B6.129S2-Ifnar1tm1Agt/Mmjaxcongenic|mutant strain|targeted mutation |
Hassert M, PLoS Pathog 2020 Dec;16(12):e1009163 Ngo VL, Cell Host Microbe 2024 Jan 23;(): |
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B6.129S2-Ighmtm1Cgn/J | MGI:2163831 | congenic|mutant strain|targeted mutation | Israelow B, bioRxiv 2021 May;(): | J:308733 | Infection|SARS-CoV-2_virus | B6.129S2-Ighmtm1Cgn/Jcongenic|mutant strain|targeted mutation |
Israelow B, bioRxiv 2021 May;(): |
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B6.129S2-Plattm1Mlg/J | MGI:2162973 | congenic|mutant strain|targeted mutation | MGI:6433845 | Plattm1Mlg | MGI:1857288 | Targeted | Null/knockout | immune system mortality/aging | MP:0005387 MP:0010768 | Gralinski LE, mBio 2013 Aug 6;4(4): | J:288556 | Infection|Pathology|SARS-CoV-MA_virus | B6.129S2-Plattm1Mlg/Jcongenic|mutant strain|targeted mutation |
MGI:6433845 | immune system mortality/aging |
Gralinski LE, mBio 2013 Aug 6;4(4): |
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B6.129S2-Serpine1tm1Mlg/J | MGI:2162090 | congenic|mutant strain|targeted mutation | MGI:3690223 | Serpine1tm1Mlg | MGI:1857287 | Targeted | Null/knockout | Coronavirus infectious disease | DOID:0080599 | cardiovascular system homeostasis/metabolism immune system liver/biliary system respiratory system mortality/aging | MP:0005385 MP:0005376 MP:0005387 MP:0005370 MP:0005388 MP:0010768 | Gralinski LE, mBio 2013 Aug 6;4(4): | J:288556 | Infection|Pathology|SARS-CoV-MA_virus | B6.129S2-Serpine1tm1Mlg/Jcongenic|mutant strain|targeted mutation |
MGI:3690223 | cardiovascular system homeostasis/metabolism immune system liver/biliary system respiratory system mortality/aging Coronavirus infectious disease |
Gralinski LE, mBio 2013 Aug 6;4(4): |
B6.129S2-Tcratm1Mom/J | MGI:2162335 | congenic|mutant strain|targeted mutation | Hilligan KL, Nat Commun 2023 Dec 12;14(1):8229 | J:343550 | Infection|SARS-CoV-2_virus|Treatment | B6.129S2-Tcratm1Mom/Jcongenic|mutant strain|targeted mutation |
Hilligan KL, Nat Commun 2023 Dec 12;14(1):8229 |
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B6.129S2-Tnfrsf1btm1Mwm/J | MGI:2164652 | congenic|mutant strain|targeted mutation | MGI:3580520 | Tnfrsf1btm1Mwm | MGI:1857262 | Targeted | Null/knockout | cellular hematopoietic system immune system | MP:0005384 MP:0005397 MP:0005387 | McDermott JE, BMC Syst Biol 2016 Sep 23;10(1):93 | J:288523 | Pathology|SARS-CoV-MA_virus | B6.129S2-Tnfrsf1btm1Mwm/Jcongenic|mutant strain|targeted mutation |
MGI:3580520 | cellular hematopoietic system immune system |
McDermott JE, BMC Syst Biol 2016 Sep 23;10(1):93 |
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B6;129S4-C3tm1Crr/J | MGI:2165043 | mutant stock|targeted mutation | MGI:3799624 | C3tm1Crr | MGI:1861799 | Targeted | Null/knockout | homeostasis/metabolism immune system nervous system vision/eye | MP:0005376 MP:0005387 MP:0003631 MP:0005391 | Gralinski LE, mBio 2018 Oct 9;9(5): | J:286325 | Pathology|SARS-CoV-MA_virus | B6;129S4-C3tm1Crr/Jmutant stock|targeted mutation |
MGI:3799624 | homeostasis/metabolism immune system nervous system vision/eye |
Gralinski LE, mBio 2018 Oct 9;9(5): |
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B6.129S4-Ccr1tm1Gao | MGI:3614571 | congenic|mutant strain|targeted mutation | MGI:3614443 | Ccr1tm1Gao | MGI:1931850 | Targeted | Null/knockout | Coronavirus infectious disease | DOID:0080599 | cardiovascular system cellular hematopoietic system homeostasis/metabolism immune system respiratory system mortality/aging | MP:0005385 MP:0005384 MP:0005397 MP:0005376 MP:0005387 MP:0005388 MP:0010768 | Sheahan T, PLoS Pathog 2008 Dec;4(12):e1000240 | J:162707 | Pathology|SARS-CoV-MA_virus | B6.129S4-Ccr1tm1Gaocongenic|mutant strain|targeted mutation |
MGI:3614443 | cardiovascular system cellular hematopoietic system homeostasis/metabolism immune system respiratory system mortality/aging Coronavirus infectious disease |
Sheahan T, PLoS Pathog 2008 Dec;4(12):e1000240 |
B6.129S4-Ccr2tm1Ifc/J | MGI:3038272 | congenic|mutant strain|targeted mutation | MGI:3580323 | Ccr2tm1Ifc | MGI:2158213 | Targeted | Null/knockout | cellular hematopoietic system immune system nervous system skeleton mortality/aging neoplasm | MP:0005384 MP:0005397 MP:0005387 MP:0003631 MP:0005390 MP:0010768 MP:0002006 | Chen BP, J Immunol 2001 Oct 15;167(8):4585-92 | J:106738 | Mouse_Hepatitis_virus|Pathology | B6.129S4-Ccr2tm1Ifc/Jcongenic|mutant strain|targeted mutation |
MGI:3580323 | cellular hematopoietic system immune system nervous system skeleton mortality/aging neoplasm |
Chen BP, J Immunol 2001 Oct 15;167(8):4585-92 |
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B6(129S4)-Ly6etm1c(EUCOMM)Hmgu/JwschJ | MGI:6507729 | mutant strain|targeted mutation | Pfaender S, Nat Microbiol 2020 Jul 23;(): | J:291868 | Gene|HCoV-229E_virus|HCoV-OC43_virus|MERS-CoV_virus|Mouse_Hepatitis_virus|SARS-CoV-2_virus|SARS-CoV_virus | B6(129S4)-Ly6etm1c(EUCOMM)Hmgu/JwschJmutant strain|targeted mutation |
Pfaender S, Nat Microbiol 2020 Jul 23;(): |
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B6;129S5-Ace2tm1Lex/Mmucd | MGI:5498467 | mutant strain|targeted mutation | Jia H, Nat Commun 2020 Oct 14;11(1):5165 | J:296535 | SARS-CoV-2_virus | B6;129S5-Ace2tm1Lex/Mmucdmutant strain|targeted mutation |
Jia H, Nat Commun 2020 Oct 14;11(1):5165 |
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B6;129S6-Apaf1tm1Her/J | MGI:2178674 | mutant stock|targeted mutation | Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 | J:296686 | Pathology|SARS-CoV-2_virus|Treatment | B6;129S6-Apaf1tm1Her/Jmutant stock|targeted mutation |
Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 |
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B6.129S6-Cd4tm1Knw/J | MGI:2162768 | congenic|mutant strain|targeted mutation | Yang J, Nature 2020 Jul 29;(): | J:292665 | SARS-CoV-2_virus|Vaccine | B6.129S6-Cd4tm1Knw/Jcongenic|mutant strain|targeted mutation |
Yang J, Nature 2020 Jul 29;(): |
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B6.129S6-Ch25htm1Rus/J | MGI:4947858 | congenic|mutant strain|targeted mutation | Fessler MB, Am J Respir Cell Mol Biol 2023 Dec;69(6):638-648 | J:343658 | SARS-CoV-2_virus | B6.129S6-Ch25htm1Rus/Jcongenic|mutant strain|targeted mutation |
Fessler MB, Am J Respir Cell Mol Biol 2023 Dec;69(6):638-648 |
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B6.129S6-Nlrp3tm1Bhk/J | MGI:5465029 | congenic|mutant strain|targeted mutation | Duhalde Vega M, Sci Adv 2022 Sep 23;8(38):eabn6545 Wu J, Immunity 2021 Nov 9;54(11):2632-2649.e6 | J:331762 J:323769 | Mouse_Hepatitis_virus Gene|Pathology | B6.129S6-Nlrp3tm1Bhk/Jcongenic|mutant strain|targeted mutation |
Duhalde Vega M, Sci Adv 2022 Sep 23;8(38):eabn6545 Wu J, Immunity 2021 Nov 9;54(11):2632-2649.e6 |
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B6;129S6-Ppp1r14ctm1Uhl/J | MGI:4839337 | mutant stock|targeted mutation | MGI:6433773 | Ppp1r14ctm1Uhl | MGI:4450989 | Targeted | Null/knockout | Coronavirus infectious disease | DOID:0080599 | immune system | MP:0005387 | McDermott JE, BMC Syst Biol 2016 Sep 23;10(1):93 | J:288523 | Pathology|SARS-CoV-MA_virus | B6;129S6-Ppp1r14ctm1Uhl/Jmutant stock|targeted mutation |
MGI:6433773 | immune system Coronavirus infectious disease |
McDermott JE, BMC Syst Biol 2016 Sep 23;10(1):93 |
B6.129S6-Ptges2tm1Bhk/J | MGI:3833371 | congenic|targeted mutation | McDermott JE, BMC Syst Biol 2016 Sep 23;10(1):93 | J:288523 | Pathology|SARS-CoV-MA_virus | B6.129S6-Ptges2tm1Bhk/Jcongenic|targeted mutation |
McDermott JE, BMC Syst Biol 2016 Sep 23;10(1):93 |
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B6.129S6-Shhtm2(cre/ERT2)Cjt/J | MGI:3612945 | congenic|mutant strain|targeted mutation | Anand G, bioRxiv 2020 Dec;(): | J:298270 | Pathology|SARS-CoV-2_virus | B6.129S6-Shhtm2(cre/ERT2)Cjt/Jcongenic|mutant strain|targeted mutation |
Anand G, bioRxiv 2020 Dec;(): |
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B6.129S7-Cd47tm1Fpl/J | MGI:2165071 | congenic|mutant strain|targeted mutation | Wenzek C, iScience 2022 Dec 22;25(12):105540 | J:331693 | SARS-CoV-2_virus | B6.129S7-Cd47tm1Fpl/Jcongenic|mutant strain|targeted mutation |
Wenzek C, iScience 2022 Dec 22;25(12):105540 |
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B6.129S7-Ifngr1tm1Agt/J | MGI:2164369 | congenic|mutant strain|targeted mutation | Hilligan KL, Nat Commun 2023 Dec 12;14(1):8229 | J:343550 | Infection|SARS-CoV-2_virus|Treatment | B6.129S7-Ifngr1tm1Agt/Jcongenic|mutant strain|targeted mutation |
Hilligan KL, Nat Commun 2023 Dec 12;14(1):8229 |
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B6.129S7-Ifngtm1Ts | MGI:3713227 | congenic|mutant strain|targeted mutation | MGI:4365971 | Ifngtm1Ts | MGI:1857184 | Targeted | Null/knockout | endocrine/exocrine glands hematopoietic system immune system neoplasm mortality/aging | MP:0005379 MP:0005397 MP:0005387 MP:0002006 MP:0010768 | Parra B, J Immunol 1999 Feb 1;162(3):1641-7 | J:112048 | Infection|Mouse_Hepatitis_virus | B6.129S7-Ifngtm1Tscongenic|mutant strain|targeted mutation |
MGI:4365971 | endocrine/exocrine glands hematopoietic system immune system neoplasm mortality/aging |
Parra B, J Immunol 1999 Feb 1;162(3):1641-7 |
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B6.129S7-Ifngtm1Ts/J | MGI:2162391 | congenic|mutant strain|targeted mutation | Sun J, Cell 2020 Jun 10;(): | J:291881 | Infection|Pathology|SARS-CoV-2_virus|Treatment | B6.129S7-Ifngtm1Ts/Jcongenic|mutant strain|targeted mutation |
Sun J, Cell 2020 Jun 10;(): |
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B6.129S7-Rag1tm1Mom/J | MGI:2163461 | congenic|mutant strain|targeted mutation | Dandekar AA, Am J Pathol 2004 Feb;164(2):363-9 Glass WG, J Immunol 2004 Sep 15;173(6):4030-9 Hassan AO, Cell 2020 Jun 10;(): Israelow B, bioRxiv 2021 May;(): Mao T, bioRxiv 2021 Jun;(): Ngo VL, Cell Host Microbe 2024 Jan 23;(): | J:88552 J:92752 J:290258 J:308733 J:308656 J:345954 | Mouse_Hepatitis_virus Infection|SARS-CoV_virus Infection|SARS-CoV-2_virus|Treatment Infection|SARS-CoV-2_virus Treatment|VOC_B.1.1.7_Alpha|VOC_B.1.351_Beta|VOC_P.1_Gamma Infection|MERS-CoV-MA_virus | B6.129S7-Rag1tm1Mom/Jcongenic|mutant strain|targeted mutation |
Dandekar AA, Am J Pathol 2004 Feb;164(2):363-9 Glass WG, J Immunol 2004 Sep 15;173(6):4030-9 Hassan AO, Cell 2020 Jun 10;(): Israelow B, bioRxiv 2021 May;(): Mao T, bioRxiv 2021 Jun;(): Ngo VL, Cell Host Microbe 2024 Jan 23;(): |
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B6.129S(C)-Batf3tm1Kmm/J | MGI:5287249 | congenic|mutant strain|targeted mutation | Ngo VL, Cell Host Microbe 2024 Jan 23;(): | J:345954 | Infection|MERS-CoV-MA_virus | B6.129S(C)-Batf3tm1Kmm/Jcongenic|mutant strain|targeted mutation |
Ngo VL, Cell Host Microbe 2024 Jan 23;(): |
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B6.129S(Cg)-Stat1tm1Dlv/J | MGI:4452071 | congenic|mutant strain|targeted mutation | Hassan AO, Cell 2020 Jun 10;(): Ngo VL, Cell Host Microbe 2024 Jan 23;(): Sun J, Cell 2020 Jun 10;(): | J:290258 J:345954 J:291881 | Infection|SARS-CoV-2_virus|Treatment Infection|MERS-CoV-MA_virus Infection|Pathology|SARS-CoV-2_virus|Treatment | B6.129S(Cg)-Stat1tm1Dlv/Jcongenic|mutant strain|targeted mutation |
Hassan AO, Cell 2020 Jun 10;(): Ngo VL, Cell Host Microbe 2024 Jan 23;(): Sun J, Cell 2020 Jun 10;(): |
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B6.129S-Csf2tm1Mlg/J | MGI:5613598 | congenic|mutant strain|targeted mutation | Ngo VL, Cell Host Microbe 2024 Jan 23;(): | J:345954 | Infection|MERS-CoV-MA_virus | B6.129S-Csf2tm1Mlg/Jcongenic|mutant strain|targeted mutation |
Ngo VL, Cell Host Microbe 2024 Jan 23;(): |
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B6.129S(FVB)-Bcl6tm1.1Dent/J | MGI:5518537 | congenic|mutant strain|targeted mutation | Chen JS, bioRxiv 2021 Jun;(): | J:308655 | SARS-CoV-2_virus|VOC_B.1.351_Beta | B6.129S(FVB)-Bcl6tm1.1Dent/Jcongenic|mutant strain|targeted mutation |
Chen JS, bioRxiv 2021 Jun;(): |
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B6.129S-Notch2tm3Grid/J | MGI:4441345 | congenic|mutant strain|targeted mutation | Harb H, Immunity 2021 Apr 22;(): | J:347529 | Infection | B6.129S-Notch2tm3Grid/Jcongenic|mutant strain|targeted mutation |
Harb H, Immunity 2021 Apr 22;(): |
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B6.129S-Sftpctm1(cre/ERT2)Blh/J | MGI:5661884 | congenic|mutant strain|targeted mutation | Tang AT, bioRxiv 2021 Dec;(): Tang AT, PLoS Biol 2023 Feb;21(2):e3001989 | J:315719 J:337814 | Pathology|SARS-CoV-2_virus Pathology|SARS-CoV-2_virus|VOC_B.1.1.529_Omicron | B6.129S-Sftpctm1(cre/ERT2)Blh/Jcongenic|mutant strain|targeted mutation |
Tang AT, bioRxiv 2021 Dec;(): Tang AT, PLoS Biol 2023 Feb;21(2):e3001989 |
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B6.129S-Tnfrsf1btm1Imx Tnfrsf1atm1Imx/J | MGI:2164568 | congenic|mutant strain|targeted mutation | MGI:6433775 | Tnfrsf1atm1Imx Tnfrsf1btm1Imx | MGI:1857468 MGI:1860087 | Targeted | Null/knockout | immune system | MP:0005387 | McDermott JE, BMC Syst Biol 2016 Sep 23;10(1):93 | J:288523 | Pathology|SARS-CoV-MA_virus | B6.129S-Tnfrsf1btm1Imx Tnfrsf1atm1Imx/Jcongenic|mutant strain|targeted mutation |
MGI:6433775 | immune system |
McDermott JE, BMC Syst Biol 2016 Sep 23;10(1):93 |
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B6.129-Tlr2tm1Kir/J | MGI:2673281 | congenic|mutant strain|targeted mutation | Yang J, Nature 2020 Jul 29;(): | J:292665 | SARS-CoV-2_virus|Vaccine | B6.129-Tlr2tm1Kir/Jcongenic|mutant strain|targeted mutation |
Yang J, Nature 2020 Jul 29;(): |
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B6.129-Tnfrsf1atm1Mak/J | MGI:2164398 | congenic|mutant strain|targeted mutation | McDermott JE, BMC Syst Biol 2016 Sep 23;10(1):93 | J:288523 | Pathology|SARS-CoV-MA_virus | B6.129-Tnfrsf1atm1Mak/Jcongenic|mutant strain|targeted mutation |
McDermott JE, BMC Syst Biol 2016 Sep 23;10(1):93 |
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B6.129X1-Fgl2tm1Pam | MGI:3583761 | congenic|mutant strain|targeted mutation | MGI:3583697 | Fgl2tm1Pam | MGI:3582343 | Targeted | Null/knockout|Reporter | cardiovascular system cellular growth/size/body hematopoietic system homeostasis/metabolism immune system renal/urinary system mortality/aging | MP:0005385 MP:0005384 MP:0005378 MP:0005397 MP:0005376 MP:0005387 MP:0005367 MP:0010768 | Marsden PA, J Clin Invest 2003 Jul;112(1):58-66 | J:99453 | Mouse_Hepatitis_virus | B6.129X1-Fgl2tm1Pamcongenic|mutant strain|targeted mutation |
MGI:3583697 | cardiovascular system cellular growth/size/body hematopoietic system homeostasis/metabolism immune system renal/urinary system mortality/aging |
Marsden PA, J Clin Invest 2003 Jul;112(1):58-66 |
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B6.129X1-Ifngtm1Yiw | MGI:6430477 | congenic|mutant strain|targeted mutation | MGI:6430478 | Ifngtm1Yiw | MGI:3036127 | Targeted | Null/knockout | behavior/neurological digestive/alimentary system growth/size/body homeostasis/metabolism immune system liver/biliary system mortality/aging | MP:0005386 MP:0005381 MP:0005378 MP:0005376 MP:0005387 MP:0005370 MP:0010768 | Kyuwa S, J Virol 1998 Nov;72(11):9286-90 Kyuwa S, Virus Res 2002 Feb 26;83(1-2):169-77 | J:50405 J:91691 | Mouse_Hepatitis_virus|Pathology Infection|Mouse_Hepatitis_virus|Pathology | B6.129X1-Ifngtm1Yiwcongenic|mutant strain|targeted mutation |
MGI:6430478 | behavior/neurological digestive/alimentary system growth/size/body homeostasis/metabolism immune system liver/biliary system mortality/aging |
Kyuwa S, J Virol 1998 Nov;72(11):9286-90 Kyuwa S, Virus Res 2002 Feb 26;83(1-2):169-77 |
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B6.129X1-Notch1tm2Rko/GridJ | MGI:3777345 | congenic|targeted mutation | Harb H, Immunity 2021 Apr 22;(): | J:347529 | Infection | B6.129X1-Notch1tm2Rko/GridJcongenic|targeted mutation |
Harb H, Immunity 2021 Apr 22;(): |
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B6.B10ScN-Tlr4lps-del/JthJ | MGI:3777588 | congenic|spontaneous mutation | Yang J, Nature 2020 Jul 29;(): | J:292665 | SARS-CoV-2_virus|Vaccine | B6.B10ScN-Tlr4lps-del/JthJcongenic|spontaneous mutation |
Yang J, Nature 2020 Jul 29;(): |
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B6C3-Tg(APP695)3Dbo Tg(PSEN1)5Dbo/Mmjax | MGI:2174641 | mutant strain|transgenic | Chen J, Transl Psychiatry 2023 Dec 16;13(1):396 | J:348471 | Gene|Infection|SARS-CoV-2_virus | B6C3-Tg(APP695)3Dbo Tg(PSEN1)5Dbo/Mmjaxmutant strain|transgenic |
Chen J, Transl Psychiatry 2023 Dec 16;13(1):396 |
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B6.Cg-Aicdatm1Hon/HonRbrc | MGI:3690652 | congenic|mutant strain|targeted mutation | Luo Y, Signal Transduct Target Ther 2022 Jan 4;7(1):7 | J:333746 | SARS-CoV-2_virus|Vaccine | B6.Cg-Aicdatm1Hon/HonRbrccongenic|mutant strain|targeted mutation |
Luo Y, Signal Transduct Target Ther 2022 Jan 4;7(1):7 |
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B6.Cg-B2mtm1Unc Cd4tm1Litt H2-Ab1b-tm1Doi Tg(Cd4-CD4)2362Litt Tg(H2-Aa-HLA-DPA1)1Lone Tg(H2-Ab1-HLA-DPB1)1Lone Tg(HLA-A/H2-D/B2M)1Bpe/Orl | MGI:5494679 | congenic|mutant strain|targeted mutation|transgenic | Brentville VA, bioRxiv 2021 Jun;(): | J:308658 | SARS-CoV-2_virus|Vaccine | B6.Cg-B2mtm1Unc Cd4tm1Litt H2-Ab1b-tm1Doi Tg(Cd4-CD4)2362Litt Tg(H2-Aa-HLA-DPA1)1Lone Tg(H2-Ab1-HLA-DPB1)1Lone Tg(HLA-A/H2-D/B2M)1Bpe/Orlcongenic|mutant strain|targeted mutation|transgenic |
Brentville VA, bioRxiv 2021 Jun;(): |
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B6(Cg)-C1qatm1d(EUCOMM)Wtsi/TennJ | MGI:6151470 | mutant strain|targeted mutation | Ngo VL, Cell Host Microbe 2024 Jan 23;(): | J:345954 | Infection|MERS-CoV-MA_virus | B6(Cg)-C1qatm1d(EUCOMM)Wtsi/TennJmutant strain|targeted mutation |
Ngo VL, Cell Host Microbe 2024 Jan 23;(): |
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B6.Cg-Ces1ctm1.1Loc/J | MGI:4939039 | congenic|mutant strain|targeted mutation | Martinez DR, bioRxiv 2021 Jan;(): Pruijssers AJ, Cell Rep 2020 Jul 21;32(3):107940 Zhu C, Nat Commun 2022 Aug 3;13(1):4503 | J:302135 J:298752 J:335969 | SARS-CoV-2-MA_virus|SARS-CoV-2_virus|Treatment SARS-CoV-2_virus|Treatment | B6.Cg-Ces1ctm1.1Loc/Jcongenic|mutant strain|targeted mutation |
Martinez DR, bioRxiv 2021 Jan;(): Pruijssers AJ, Cell Rep 2020 Jul 21;32(3):107940 Zhu C, Nat Commun 2022 Aug 3;13(1):4503 |
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B6(Cg)-Ctnnb1tm1Knw/J | MGI:5796192 | mutant strain|targeted mutation | Harb H, Immunity 2021 Apr 22;(): | J:347529 | Infection | B6(Cg)-Ctnnb1tm1Knw/Jmutant strain|targeted mutation |
Harb H, Immunity 2021 Apr 22;(): |
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B6.Cg-Edil3Tg(Sox2-cre)1Amc/J | MGI:3800753 | congenic|transgenic | Tang AT, bioRxiv 2021 Dec;(): Tang AT, PLoS Biol 2023 Feb;21(2):e3001989 | J:315719 J:337814 | Pathology|SARS-CoV-2_virus Pathology|SARS-CoV-2_virus|VOC_B.1.1.529_Omicron | B6.Cg-Edil3Tg(Sox2-cre)1Amc/Jcongenic|transgenic |
Tang AT, bioRxiv 2021 Dec;(): Tang AT, PLoS Biol 2023 Feb;21(2):e3001989 |
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B6.Cg-Fcgrttm1Dcr Prkdcscid Tg(FCGRT)32Dcr/DcrJ | MGI:5424138 | congenic|mutant strain|spontaneous mutation|targeted mutation|transgenic | Halwe S, bioRxiv 2021 Jun;(): | J:308648 | SARS-CoV-2_virus|Treatment|VOC_B.1.1.7_Alpha|VOC_B.1.351_Beta | B6.Cg-Fcgrttm1Dcr Prkdcscid Tg(FCGRT)32Dcr/DcrJcongenic|mutant strain|spontaneous mutation|targeted mutation|transgenic |
Halwe S, bioRxiv 2021 Jun;(): |
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B6.Cg-Foxn1nu/J | MGI:2163103 | congenic|mutant strain|spontaneous mutation | Houtman JJ, J Neurovirol 1996 APR;2(2):101-110 | J:33974 | Mouse_Hepatitis_virus | B6.Cg-Foxn1nu/Jcongenic|mutant strain|spontaneous mutation |
Houtman JJ, J Neurovirol 1996 APR;2(2):101-110 |
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B6.Cg-Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/J | MGI:3813512 | congenic|targeted mutation | Tang AT, bioRxiv 2021 Dec;(): Tang AT, PLoS Biol 2023 Feb;21(2):e3001989 | J:315719 J:337814 | Pathology|SARS-CoV-2_virus Pathology|SARS-CoV-2_virus|VOC_B.1.1.529_Omicron | B6.Cg-Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Jcongenic|targeted mutation |
Tang AT, bioRxiv 2021 Dec;(): Tang AT, PLoS Biol 2023 Feb;21(2):e3001989 |
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B6.Cg-Gt(ROSA)26Sortm1(rtTA,EGFP)Nagy/J | MGI:3584524 | congenic|mutant strain|targeted mutation | Wu J, Immunity 2021 Nov 9;54(11):2632-2649.e6 | J:323769 | Gene|Pathology | B6.Cg-Gt(ROSA)26Sortm1(rtTA,EGFP)Nagy/Jcongenic|mutant strain|targeted mutation |
Wu J, Immunity 2021 Nov 9;54(11):2632-2649.e6 |
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B6(Cg)-Ifnar1tm1.1Ees/J | MGI:5692164 | congenic|mutant strain|targeted mutation | Anand G, bioRxiv 2020 Dec;(): | J:298270 | Pathology|SARS-CoV-2_virus | B6(Cg)-Ifnar1tm1.1Ees/Jcongenic|mutant strain|targeted mutation |
Anand G, bioRxiv 2020 Dec;(): |
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B6(Cg)-Ifnar1tm1.2Ees/J | MGI:5692173 | congenic|mutant strain|targeted mutation | Hilligan KL, Nat Commun 2023 Dec 12;14(1):8229 Mao T, bioRxiv 2021 Jun;(): Sun J, Cell 2020 Jun 10;(): Tada T, Proc Natl Acad Sci U S A 2023 Jun 6;120(23):e2303509120 Yang J, Nature 2020 Jul 29;(): | J:343550 J:308656 J:291881 J:338414 J:292665 | Infection|SARS-CoV-2_virus|Treatment Treatment|VOC_B.1.1.7_Alpha|VOC_B.1.351_Beta|VOC_P.1_Gamma Infection|Pathology|SARS-CoV-2_virus|Treatment SARS-CoV-2_virus|Treatment|VOC_B.1.1.529_Omicron SARS-CoV-2_virus|Vaccine | B6(Cg)-Ifnar1tm1.2Ees/Jcongenic|mutant strain|targeted mutation |
Hilligan KL, Nat Commun 2023 Dec 12;14(1):8229 Mao T, bioRxiv 2021 Jun;(): Sun J, Cell 2020 Jun 10;(): Tada T, Proc Natl Acad Sci U S A 2023 Jun 6;120(23):e2303509120 Yang J, Nature 2020 Jul 29;(): |
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B6(Cg)-Ightm3.1(VRC01)Nemz/J | MGI:5795592 | mutant strain|targeted mutation | Luo Y, Signal Transduct Target Ther 2022 Jan 4;7(1):7 | J:333746 | SARS-CoV-2_virus|Vaccine | B6(Cg)-Ightm3.1(VRC01)Nemz/Jmutant strain|targeted mutation |
Luo Y, Signal Transduct Target Ther 2022 Jan 4;7(1):7 |
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B6.Cg-Ly6etm1c(EUCOMM)Hmgu Commd10Tg(Vav1-icre)A2Kio | MGI:6449003 | congenic|mutant strain|targeted mutation|transgenic | MGI:6449004 | Commd10Tg(Vav1-icre)A2Kio Ly6etm1c(EUCOMM)Hmgu | MGI:2449949 MGI:6448980 | Transgenic Targeted | Null/knockout|Recombinase Conditional ready | hematopoietic system homeostasis/metabolism immune system liver/biliary system mortality/aging | MP:0005397 MP:0005376 MP:0005387 MP:0005370 MP:0010768 | Pfaender S, Nat Microbiol 2020 Jul 23;(): | J:291868 | Gene|HCoV-229E_virus|HCoV-OC43_virus|MERS-CoV_virus|Mouse_Hepatitis_virus|SARS-CoV-2_virus|SARS-CoV_virus | B6.Cg-Ly6etm1c(EUCOMM)Hmgu Commd10Tg(Vav1-icre)A2Kiocongenic|mutant strain|targeted mutation|transgenic |
MGI:6449004 | hematopoietic system homeostasis/metabolism immune system liver/biliary system mortality/aging |
Pfaender S, Nat Microbiol 2020 Jul 23;(): |
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B6.Cg-Mx1tm1.1Agsa/J | MGI:6280430 | congenic|mutant strain|targeted mutation | Anand G, bioRxiv 2020 Dec;(): | J:298270 | Pathology|SARS-CoV-2_virus | B6.Cg-Mx1tm1.1Agsa/Jcongenic|mutant strain|targeted mutation |
Anand G, bioRxiv 2020 Dec;(): |
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B6.Cg-Prkdcscid/SzJ | MGI:2163184 | congenic|mutant strain|spontaneous mutation | Houtman JJ, J Neurovirol 1996 APR;2(2):101-110 | J:33974 | Mouse_Hepatitis_virus | B6.Cg-Prkdcscid/SzJcongenic|mutant strain|spontaneous mutation |
Houtman JJ, J Neurovirol 1996 APR;2(2):101-110 |
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B6.Cg-Shhtm1(EGFP/cre)Cjt/J | MGI:3619470 | congenic|mutant strain|targeted mutation | Tang AT, bioRxiv 2021 Dec;(): Tang AT, PLoS Biol 2023 Feb;21(2):e3001989 | J:315719 J:337814 | Pathology|SARS-CoV-2_virus Pathology|SARS-CoV-2_virus|VOC_B.1.1.529_Omicron | B6.Cg-Shhtm1(EGFP/cre)Cjt/Jcongenic|mutant strain|targeted mutation |
Tang AT, bioRxiv 2021 Dec;(): Tang AT, PLoS Biol 2023 Feb;21(2):e3001989 |
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B6.Cg-Speer6-ps1Tg(Alb-cre)21Mgn/J | MGI:2164673 | congenic|mutant strain|transgenic | Wu J, Immunity 2021 Nov 9;54(11):2632-2649.e6 | J:323769 | Gene|Pathology | B6.Cg-Speer6-ps1Tg(Alb-cre)21Mgn/Jcongenic|mutant strain|transgenic |
Wu J, Immunity 2021 Nov 9;54(11):2632-2649.e6 |
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B6(Cg)-Sting1tm1.2Camb/J | MGI:5639268 | congenic|mutant strain|targeted mutation | Wu J, Immunity 2021 Nov 9;54(11):2632-2649.e6 | J:323769 | Gene|Pathology | B6(Cg)-Sting1tm1.2Camb/Jcongenic|mutant strain|targeted mutation |
Wu J, Immunity 2021 Nov 9;54(11):2632-2649.e6 |
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B6.Cg-Terctm1Rdp/J | MGI:2174164 | congenic|mutant strain|targeted mutation | Sepe S, bioRxiv 2021 Jun;(): Sepe S, EMBO Rep 2022 Feb 3;23(2):e53658 | J:309195 J:326929 | Comorbidity|Gene Gene | B6.Cg-Terctm1Rdp/Jcongenic|mutant strain|targeted mutation |
Sepe S, bioRxiv 2021 Jun;(): |
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B6.Cg-Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/Mmjax | MGI:3811801 | congenic|transgenic | Hohsfield LA, Glia 2022 May;70(5):875-891 | J:324342 | Mouse_Hepatitis_virus | B6.Cg-Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/Mmjaxcongenic|transgenic |
Hohsfield LA, Glia 2022 May;70(5):875-891 |
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B6.Cg-Tg(Cd4-cre)1Cwi/BfluJ | MGI:5566534 | congenic|mutant strain|transgenic | Chen JS, bioRxiv 2021 Jun;(): | J:308655 | SARS-CoV-2_virus|VOC_B.1.351_Beta | B6.Cg-Tg(Cd4-cre)1Cwi/BfluJcongenic|mutant strain|transgenic |
Chen JS, bioRxiv 2021 Jun;(): |
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B6.Cg-Tg(DPP4)2Nnag | MGI:6403117 | congenic|mutant strain|transgenic | MGI:6403118 | Tg(DPP4)2Nnag | MGI:6403115 | Transgenic | Humanized sequence|Inserted expressed sequence | Middle East respiratory syndrome | DOID:0080642 | homeostasis/metabolism immune system respiratory system | MP:0005376 MP:0005387 MP:0005388 | Iwata-Yoshikawa N, J Virol 2019 Mar 15;93(6): | J:286321 | Infection|MERS-CoV_virus | B6.Cg-Tg(DPP4)2Nnagcongenic|mutant strain|transgenic |
MGI:6403118 | homeostasis/metabolism immune system respiratory system Middle East respiratory syndrome |
Iwata-Yoshikawa N, J Virol 2019 Mar 15;93(6): |
B6.Cg-Tg(FOXJ1-ACE2)1Rba/Mmnc | MGI:6415225 | congenic|mutant strain|transgenic | Jia H, Nat Commun 2020 Oct 14;11(1):5165 Menachery VD, Proc Natl Acad Sci U S A 2016 Mar 15;113(11):3048-53 | J:296535 J:287092 | SARS-CoV-2_virus Infection | B6.Cg-Tg(FOXJ1-ACE2)1Rba/Mmnccongenic|mutant strain|transgenic |
Jia H, Nat Commun 2020 Oct 14;11(1):5165 Menachery VD, Proc Natl Acad Sci U S A 2016 Mar 15;113(11):3048-53 |
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B6.Cg-Tg(Itgax-cre)1-1Reiz/J | MGI:3763375 | congenic|mutant strain|transgenic | Adamska JZ, Cell Rep 2023 Jan 31;42(1):112038 Anand G, bioRxiv 2020 Dec;(): | J:333092 J:298270 | Gene|VOC_B.1.351_Beta Pathology|SARS-CoV-2_virus | B6.Cg-Tg(Itgax-cre)1-1Reiz/Jcongenic|mutant strain|transgenic |
Adamska JZ, Cell Rep 2023 Jan 31;42(1):112038 Anand G, bioRxiv 2020 Dec;(): |
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B6.Cg-Tg(K18-ACE2)2Prlmn/J | MGI:6389236 | congenic|mutant strain|transgenic | MGI:6455041 | Tg(K18-ACE2)2Prlmn | MGI:6389235 | Transgenic | Humanized sequence|Inserted expressed sequence | COVID-19 | DOID:0080600 | behavior/neurological cardiovascular system cellular growth/size/body hematopoietic system homeostasis/metabolism immune system liver/biliary system nervous system respiratory system vision/eye mortality/aging | MP:0005386 MP:0005385 MP:0005384 MP:0005378 MP:0005397 MP:0005376 MP:0005387 MP:0005370 MP:0003631 MP:0005388 MP:0005391 MP:0010768 | Achdout H, Nat Commun 2021 Oct 5;12(1):5819 Afkhami S, bioRxiv 2021 Jul;(): Amarilla AA, Nat Commun 2021 Jun 8;12(1):3431 Americo JL, Proc Natl Acad Sci U S A 2022 Jun 14;119(24):e2202069119 Amruta N, bioRxiv 2021 May;(): Avila-Nieto C, Nat Commun 2024 Mar 21;15(1):2349 Awosanya OD, Bone 2022 Jan;154():116227 Barreiro A, bioRxiv 2021 Dec;(): Beaudoin-Bussieres G, bioRxiv 2021 Sep;(): Belouzard S, bioRxiv 2021 Jun;(): Bertoglio F, Cell Rep 2021 Jul 27;36(4):109433 Biswas R, bioRxiv 2021 Feb;(): Cao L, Sci Transl Med 2022 Sep 7;14(661):eabm7621 Carossino M, bioRxiv 2021 Jan;(): Case JB, Cell Host Microbe 2020 Sep 9;28(3):465-474.e4 Ceon E, bioRxiv 2022 Jan;(): Chan CEZ, PLoS One 2021;16(6):e0253487 Chaouat AE, PLoS Pathog 2021 Dec;17(12):e1010175 Chaparian RR, bioRxiv 2021 Apr;(): Chen EC, Cell Rep 2021 Aug 24;36(8):109604 Chen IP, Cell Rep 2022 Jul 19;40(3):111088 Chen JS, bioRxiv 2020 Sep 25;(): Chen JS, bioRxiv 2021 Jun;(): Chen JS, J Virol 2021 Jan 13;(): Chong Z, bioRxiv 2022;(): Chong Z, Cell Rep 2022 May 10;39(6):110799 Clark JJ, bioRxiv 2020;(): Colunga Biancatelli R, Am J Physiol Lung Cell Mol Physiol 2021 Jun;(): Conforti A, bioRxiv 2021 Jun;(): Dangi T, J Clin Invest 2022 Dec 1;132(23): de Almeida L, Sci Adv 2022 Sep 16;8(37):eabo5400 Do MH, PLoS One 2023;18(9):e0291537 Drayman N, Science 2021 Aug 20;373(6557):931-936 Dubuc I, Front Immunol 2022;13():893792 Dugan HL, Immunity 2021 Jun 8;54(6):1290-1303.e7 Duty JA, Med 2022 Oct 14;3(10):705-721.e11 Elia U, bioRxiv 2021 Mar;(): El-Shennawy L, Nat Commun 2022 Jan 20;13(1):405 Ewart G, PLoS Pathog 2023 Aug;19(8):e1011328 Fessler MB, Am J Respir Cell Mol Biol 2023 Dec;69(6):638-648 Fumagalli V, bioRxiv 2021 Aug;(): Garcia-Arriaza J, J Virol 2021 Jan 7;(): Garcia-Ayllon MS, FASEB J 2021 Aug;35(8):e21745 Gawish R, Elife 2022 Jan 13;11():e74623 Gioia U, Nat Cell Biol 2023 Apr;25(4):550-564 Golden JW, JCI Insight 2020 Aug 25;(): Goncalves R, iScience 2023 Feb 17;26(2):105972 Grandi A, bioRxiv 2021 Jul;(): Greer CD, bioRxiv 2021 Aug;(): Gretebeck LM, Curr Opin Virol 2015 Aug;13():123-9 Hassan AO, Cell 2020 Oct 1;183(1):169-184.e13 Hassan AO, Cell Rep 2021 Jul 27;36(4):109452 Hassert M, PLoS Pathog 2020 Dec;16(12):e1009163 Hastie KM, Cell Rep 2023 May 30;42(5):112421 Hauser BM, Cell Rep 2022 Mar 22;38(12):110561 Hilligan KL, bioRxiv 2021 Aug;(): Hilligan KL, Nat Commun 2023 Dec 12;14(1):8229 Ho JSY , bioRxiv 2020 Dec;(): Ho JSY, Cell 2021 May 13;184(10):2618-2632.e17 Hong J, bioRxiv 2021 Oct;(): Hong J, Proc Natl Acad Sci U S A 2022 May 3;119(18):e2201433119 Humphries F, Sci Immunol 2021 May 18;6(59): Hunt AC, bioRxiv 2021 Jul;(): Israelow B, bioRxiv 2021 May;(): Israelow B, Sci Immunol 2021 Oct 15;6(64):eabl4509 Jaki L, Nat Commun 2023 Apr 10;14(1):1999 Jennewein MF, Cell Rep 2021 Jul 13;36(2):109353 Jeong GU, bioRxiv 2022;(): Jeong H, Dis Model Mech 2022 Nov 1;15(11):dmm049632 Jia H, Nat Commun 2020 Oct 14;11(1):5165 Joag V, J Immunol 2021 Mar 1;206(5):931-935 Johnson BA, Nature 2021 Mar;591(7849):293-299 Joyce MG, Cell Rep 2021 Dec 21;37(12):110143 Kaiser R, JCI Insight 2021 Sep 22;6(18):e150862 Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 Kehrer T, Cell Host Microbe 2023 Oct 11;31(10):1668-1684.e12 Khaddaj-Mallat R, Neurobiol Dis 2021 Dec;161():105561 Kim GN, PLoS Pathog 2021 Dec;17(12):e1010092 Kim JW, Front Immunol 2023;14():1271508 Konrath KM, Cell Rep 2022 Feb 1;38(5):110318 Ku MW, bioRxiv 2021 Feb;(): Ku MW, EMBO Mol Med 2021 Dec 7;13(12):e14459 Lee KS, bioRxiv 2022;(): Lee S, Nature 2021 Nov;599(7884):283-289 Lee YJ, Am J Pathol 2023 Jul;193(7):866-882 Li K, mBio 2021 Aug 31;12(4):e0097021 Lin X, bioRxiv 2021 Dec;(): Liu R, bioRxiv 2021 Jan;(): Liu R, Proc Natl Acad Sci U S A 2021 Mar 23;118(12):e2026785118 Li W, Cell Rep 2022 Jan 11;38(2):110210 Lu A, Int J Mol Sci 2024 Feb 8;25(4): Makdasi E, Cell Rep 2021 Sep 7;36(10):109679 Manangeeswaran M, Front Immunol 2022;13():919815 Mao T, bioRxiv 2021 Jun;(): Mao T, bioRxiv 2022;(): Mao T, Proc Natl Acad Sci U S A 2024 Apr 30;121(18):e2319566121 Mao T, Science 2022 Nov 25;378(6622):eabo2523 Martin-Lopez E, eNeuro 2024 Jun;11(6):ENEURO.0106-24.2024 Marx S, bioRxiv 2021 Aug;(): Matchett WE, J Immunol 2021 Jun 30;(): McCray PB Jr, J Virol 2007 Jan;81(2):813-21 Mei M, Proc Natl Acad Sci U S A 2024 May 28;121(22):e2314166121 Mejia OR, bioRxiv 2021 Nov;(): Nagai M, Nat Commun 2023 Jun 30;14(1):3863 Natekar JP, bioRxiv 2022 Apr;(): Noy-Porat T, bioRxiv 2021 Feb;(): Noy-Porat T, iScience 2021 May 21;24(5):102479 Oktay E, Commun Biol 2023 Mar 23;6(1):308 Oladunni FS, Nat Commun 2020 Nov 30;11(1):6122 Olivarria GM, bioRxiv 2021 Nov;(): Oliveira VLS, Front Immunol 2024;15():1378591 Ordonez AA, Commun Biol 2022 Mar 18;5(1):242 Perez P, Front Immunol 2022;13():995235 Perez P, Front Immunol 2023;14():1264323 Puhl AC, bioRxiv 2021;(): Puhl AC, bioRxiv 2021 Dec;(): Qin Z, Theranostics 2021;11(16):8076-8091 Radvak P, bioRxiv 2021 Jun;(): Rathnasinghe R, Emerg Microbes Infect 2020 Oct 17;():1-19 Rizvi ZA, Commun Biol 2023 Sep 13;6(1):935 Roberts LM, J Immunol 2021 Nov 15;207(10):2399-2404 Robertson SJ, bioRxiv 2021 Sep;(): Robertson SJ, Nat Commun 2023 Jul 25;14(1):4481 Rosenfeld R, Nat Commun 2021 Feb 11;12(1):944 Salzer R, bioRxiv 2021 May;(): Scaglione A, bioRxiv 2021 Jun;(): Scaglione A, Front Immunol 2021;12():719077 Schepens B, Sci Transl Med 2021 Nov 24;13(621):eabi7826 Seehusen F, bioRxiv 2021 Apr;(): Shapira T, bioRxiv 2021 May;(): Silvas J, bioRxiv 2021 Mar;(): Sims JJ, bioRxiv 2021 Apr;(): Slamanig S, EBioMedicine 2024 Jun 6;105():105185 Smeyne RJ, bioRxiv 2022 Feb;(): Sohn SY, mBio 2021 Nov 2;():e0275621 Song E, J Exp Med 2021 Mar 1;218(3): Soni DK, bioRxiv 2020 Dec;(): Suberi A, Sci Transl Med 2023 Aug 16;15(709):eabq0603 Subramaniam S, bioRxiv 2021 Aug;(): Sun CP, PLoS Pathog 2021 Aug;17(8):e1009758 Su P, Mol Brain 2022 Aug 9;15(1):71 Suryadevara N, J Clin Invest 2022 Jun 1;132(11):e159062 Syenina A, PLoS Biol 2022 May;20(5):e3001643 Tada T, Cell Rep 2020 Dec 22;33(12):108528 Tada T, Proc Natl Acad Sci U S A 2023 Jun 6;120(23):e2303509120 Tarres-Frexas F, bioRxiv 2021 Aug;(): Tatham L, bioRxiv 2022;(): Turan RD, Sci Rep 2021 Aug 4;11(1):15799 Ullah i, bioRxiv 2021 Mar;(): Ullah I, iScience 2024 Mar 15;27(3):109049 van Bergen J, JCI Insight 2023 Nov 8;8(21): VanBlargan LA, Immunity 2021 Aug 19;(): Van Dyke MC, bioRxiv 2021 May;(): van Huizen M, PLoS Pathog 2024 Mar;20(3):e1012100 Venzon M, bioRxiv 2021 Jul;(): Villadiego J, Nat Neurosci 2023 Feb;26(2):226-238 Walls AC, Cell Rep 2022 Aug 30;40(9):111299 Weiss S, Int J Mol Sci 2023 May 5;24(9): Wenzel J, Nat Neurosci 2021 Nov;24(11):1522-1533 White KM, Science 2021 Feb 26;371(6532):926-931 Winkler ES, bioRxiv 2020 Dec;(): Winkler ES, J Virol 2022 Jan 12;96(1):e0151121 Winkler ES, Nat Immunol 2020 Aug 24;(): Xiao Y, Cell 2021 Dec 9;184(25):6037-6051.e14 Yang JH, Sci Rep 2023 Feb 27;13(1):3303 Yang S, J Med Virol 2022 Aug;94(8):3605-3612 Ying B, bioRxiv 2022 Feb;(): Ying B, Sci Transl Med 2022 Feb 2;14(630):eabm3302 Zhang L, bioRxiv 2022 Mar;(): Zhang L, EMBO Mol Med 2022 Sep 12;():e16109 Zhang X, Cell 2021 Apr 15;184(8):2229-2238.e13 Zheng J, bioRxiv 2020 Aug 10;(): Zheng J, Nature 2021 Jan;589(7843):603-607 Zheng M, Nat Immunol 2021 Jul;22(7):829-838 Zhu C, Nat Commun 2022 Aug 3;13(1):4503 Zumla A, Nat Rev Drug Discov 2016 May;15(5):327-47 | J:335907 J:308640 J:335897 J:335960 J:308724 J:349496 J:319441 J:315723 J:310110 J:308621 J:335929 J:302158 J:348328 J:300428 J:294058 J:321756 J:309634 J:335919 J:308713 J:335928 J:331767 J:298866 J:308655 J:300110 J:321761 J:325089 J:296067 J:309512 J:308652 J:348326 J:331763 J:349970 J:336017 J:335961 J:335898 J:349963 J:303462 J:335924 J:343775 J:343658 J:308584 J:300041 J:335902 J:318828 J:339694 J:294084 J:348327 J:308639 J:308745 J:284000 J:335892 J:309629 J:319459 J:338412 J:335945 J:309197 J:343550 J:298250 J:308894 J:313447 J:335952 J:333769 J:308637 J:308733 J:331753 J:348329 J:335899 J:321757 J:348325 J:296535 J:303898 J:307033 J:335935 J:313337 J:296686 J:349972 J:319440 J:319447 J:349971 J:335933 J:302144 J:319366 J:321763 J:334872 J:343773 J:313329 J:315744 J:299104 J:303465 J:335931 J:349976 J:335930 J:331765 J:308656 J:321770 J:349979 J:335986 J:349938 J:308571 J:348320 J:283648 J:349980 J:315717 J:337953 J:324941 J:302148 J:308896 J:335997 J:300960 J:315722 J:348063 J:335939 J:335976 J:343770 J:311915 J:316769 J:319458 J:308643 J:296397 J:340506 J:335918 J:310124 J:338561 J:303472 J:308749 J:308666 J:335910 J:335943 J:304647 J:308716 J:302912 J:304613 J:350298 J:322638 J:312952 J:302314 J:299096 J:343790 J:309192 J:322631 J:331766 J:335949 J:335947 J:313439 J:338414 J:308579 J:321766 J:309630 J:303209 J:348954 J:349973 J:336018 J:308721 J:349977 J:308642 J:336189 J:328107 J:336005 J:323957 J:303457 J:299082 J:331773 J:294083 J:317125 J:335996 J:339218 J:321873 J:336008 J:324936 J:330045 J:305460 J:293212 J:303220 J:308903 J:335969 J:283999 | Comorbidity|SARS-CoV-2_virus SARS-CoV-2_virus|Vaccine|VOC_B.1.1.7_Alpha|VOC_B.1.351_Beta Pathology|SARS-CoV-2_virus SARS-CoV-2_virus|Vaccine|Variant SARS-CoV-2_virus|Treatment SARS-CoV-2_virus|Vaccine|VOC_B.1.1.529_Omicron|VOC_B.1.351_Beta SARS-CoV-2_virus|Vaccine SARS-CoV-2_virus Gene|SARS-CoV-2_virus SARS-CoV-2_virus|Treatment|Variant SARS-CoV-2_virus|VOC_B.1.351_Beta SARS-CoV-2_virus|Treatment|VOC_B.1.1.529_Omicron|VOC_B.1.351_Beta Comorbidity|Pathology|SARS-CoV-2_virus SARS-CoV-2_virus|Treatment|VOC_B.1.1.529_Omicron Infection|SARS-CoV-2_virus Vaccine Pathology|SARS-CoV-2-MA_virus Infection|Pathology|SARS-CoV-2_virus|Sex_bias Pathology|SARS-CoV-2_virus|VOC_B.1.1.529_Omicron|VOC_B.1.1.7_Alpha|VOC_B.1.617.2_Delta MERS-CoV_virus|SARS-CoV_virus SARS-CoV-2_virus|Treatment|VOC_B.1.1.7_Alpha Infection|SARS-CoV-2_virus|Treatment SARS-CoV-2_virus|Treatment|VOC_B.1.1.7_Alpha|VOC_B.1.351_Beta|VOC_B.1.617.2_Delta|VOC_P.1_Gamma SARS-CoV-2_virus|Treatment|VOC_B.1.351_Beta|VOC_B.1.617.2_Delta SARS-CoV-2_virus|Treatment|VOC_B.1.1.7_Alpha|VOC_B.1.351_Beta|VOC_P.1_Gamma SARS-CoV-2_virus|Treatment|VOC_B.1.351_Beta Pathology|SARS-CoV-2_virus|Treatment Infection|Pathology|SARS-CoV-2_virus|Variant SARS-CoV-2_virus|Treatment|VOC_B.1.617.2_Delta SARS-CoV-2_virus|Vaccine|VOC_P.1_Gamma Pathology|VOC_B.1.617.2_Delta Pathology|SARS-CoV-2_virus|VOC_B.1.1.529_Omicron|VOC_B.1.617.2_Delta MERS-CoV_virus|SARS-CoV-2_virus|Treatment Gene|Pathology|SARS-CoV-2_virus SARS-CoV-2_virus|Treatment|VOC_B.1.1.7_Alpha|VOC_B.1.351_Beta Treatment|VOC_B.1.1.7_Alpha|VOC_B.1.351_Beta|VOC_P.1_Gamma Infection|SARS-CoV_virus Comorbidity|SARS-CoV-2-MA_virus|SARS-CoV-2_virus SARS-CoV-2_virus|VOC_B.1.1.7_Alpha Infection|SARS-CoV-2-MA_virus|SARS-CoV-2_virus|VOC_B.1.1.529_Omicron|VOC_B.1.1.7_Alpha|VOC_B.1.351_Beta|VOC_B.1.617.2_Delta Mouse_Hepatitis_virus|SARS-CoV-2_virus|Treatment|VOC_P.1_Gamma SARS-CoV-2_virus|Treatment|VOC_B.1.1.529_Omicron|VOC_B.1.617.2_Delta SARS-CoV-2_virus|Vaccine|VOC_B.1.351_Beta Mouse_Hepatitis_virus|SARS-CoV-2_virus|Treatment Pathology|SARS-CoV-2_virus|VOC_B.1.1.7_Alpha|VOC_B.1.351_Beta Pathology|SARS-CoV-2_virus|VOC_B.1.1.529_Omicron Infection|Pathology|SARS-CoV-2_virus SARS-CoV-2_virus|Treatment|Vaccine PASC|SARS-CoV-2_virus Infection|SARS-CoV-2_virus|VOC_B.1.351_Beta Treatment|VOC_B.1.1.529_Omicron|VOC_B.1.617.2_Delta SARS-CoV-2_virus|SARS-CoV_virus|Vaccine|VOC_B.1.1.529_Omicron Pathology|SARS-CoV-2_virus|Vaccine SARS-CoV-2_virus|Vaccine|Variant|VOC_B.1.351_Beta Pathology|SARS-CoV-2_virus|VOC_B.1.351_Beta Infection|SARS-CoV-2_virus|VOC_B.1.1.7_Alpha|VOC_B.1.351_Beta SARS-CoV-2_virus|Treatment|VOC_B.1.1.7_Alpha|VOC_B.1.427|VOC_B.1.617.2_Delta Pathology|SARS-CoV-2_virus|VOC_B.1.617.2_Delta Vaccine|VOC_B.1.1.529_Omicron SARS-CoV-2-MA_virus|SARS-CoV-2_virus|Vaccine|VOC_B.1.1.7_Alpha|VOC_B.1.351_Beta|VOC_B.1.617.2_Delta SARS-CoV-2_virus|Treatment|Variant|VOC_B.1.1.529_Omicron|VOC_P.1_Gamma | B6.Cg-Tg(K18-ACE2)2Prlmn/Jcongenic|mutant strain|transgenic |
MGI:6455041 | behavior/neurological cardiovascular system cellular growth/size/body hematopoietic system homeostasis/metabolism immune system liver/biliary system nervous system respiratory system vision/eye mortality/aging COVID-19 |
Achdout H, Nat Commun 2021 Oct 5;12(1):5819 Afkhami S, bioRxiv 2021 Jul;(): Amarilla AA, Nat Commun 2021 Jun 8;12(1):3431 Americo JL, Proc Natl Acad Sci U S A 2022 Jun 14;119(24):e2202069119 Amruta N, bioRxiv 2021 May;(): Avila-Nieto C, Nat Commun 2024 Mar 21;15(1):2349 Awosanya OD, Bone 2022 Jan;154():116227 Barreiro A, bioRxiv 2021 Dec;(): Beaudoin-Bussieres G, bioRxiv 2021 Sep;(): Belouzard S, bioRxiv 2021 Jun;(): Bertoglio F, Cell Rep 2021 Jul 27;36(4):109433 Biswas R, bioRxiv 2021 Feb;(): Cao L, Sci Transl Med 2022 Sep 7;14(661):eabm7621 Carossino M, bioRxiv 2021 Jan;(): Case JB, Cell Host Microbe 2020 Sep 9;28(3):465-474.e4 Ceon E, bioRxiv 2022 Jan;(): Chan CEZ, PLoS One 2021;16(6):e0253487 Chaouat AE, PLoS Pathog 2021 Dec;17(12):e1010175 Chaparian RR, bioRxiv 2021 Apr;(): Chen EC, Cell Rep 2021 Aug 24;36(8):109604 Chen IP, Cell Rep 2022 Jul 19;40(3):111088 Chen JS, bioRxiv 2020 Sep 25;(): Chen JS, bioRxiv 2021 Jun;(): Chen JS, J Virol 2021 Jan 13;(): Chong Z, bioRxiv 2022;(): Chong Z, Cell Rep 2022 May 10;39(6):110799 Clark JJ, bioRxiv 2020;(): Colunga Biancatelli R, Am J Physiol Lung Cell Mol Physiol 2021 Jun;(): Conforti A, bioRxiv 2021 Jun;(): Dangi T, J Clin Invest 2022 Dec 1;132(23): de Almeida L, Sci Adv 2022 Sep 16;8(37):eabo5400 Do MH, PLoS One 2023;18(9):e0291537 Drayman N, Science 2021 Aug 20;373(6557):931-936 Dubuc I, Front Immunol 2022;13():893792 Dugan HL, Immunity 2021 Jun 8;54(6):1290-1303.e7 Duty JA, Med 2022 Oct 14;3(10):705-721.e11 Elia U, bioRxiv 2021 Mar;(): El-Shennawy L, Nat Commun 2022 Jan 20;13(1):405 Ewart G, PLoS Pathog 2023 Aug;19(8):e1011328 Fessler MB, Am J Respir Cell Mol Biol 2023 Dec;69(6):638-648 Fumagalli V, bioRxiv 2021 Aug;(): Garcia-Arriaza J, J Virol 2021 Jan 7;(): Garcia-Ayllon MS, FASEB J 2021 Aug;35(8):e21745 Gawish R, Elife 2022 Jan 13;11():e74623 Gioia U, Nat Cell Biol 2023 Apr;25(4):550-564 Golden JW, JCI Insight 2020 Aug 25;(): Goncalves R, iScience 2023 Feb 17;26(2):105972 Grandi A, bioRxiv 2021 Jul;(): Greer CD, bioRxiv 2021 Aug;(): Gretebeck LM, Curr Opin Virol 2015 Aug;13():123-9 Hassan AO, Cell 2020 Oct 1;183(1):169-184.e13 Hassan AO, Cell Rep 2021 Jul 27;36(4):109452 Hassert M, PLoS Pathog 2020 Dec;16(12):e1009163 Hastie KM, Cell Rep 2023 May 30;42(5):112421 Hauser BM, Cell Rep 2022 Mar 22;38(12):110561 Hilligan KL, bioRxiv 2021 Aug;(): Hilligan KL, Nat Commun 2023 Dec 12;14(1):8229 Ho JSY , bioRxiv 2020 Dec;(): Ho JSY, Cell 2021 May 13;184(10):2618-2632.e17 Hong J, bioRxiv 2021 Oct;(): Hong J, Proc Natl Acad Sci U S A 2022 May 3;119(18):e2201433119 Humphries F, Sci Immunol 2021 May 18;6(59): Hunt AC, bioRxiv 2021 Jul;(): Israelow B, bioRxiv 2021 May;(): Israelow B, Sci Immunol 2021 Oct 15;6(64):eabl4509 Jaki L, Nat Commun 2023 Apr 10;14(1):1999 Jennewein MF, Cell Rep 2021 Jul 13;36(2):109353 Jeong GU, bioRxiv 2022;(): Jeong H, Dis Model Mech 2022 Nov 1;15(11):dmm049632 Jia H, Nat Commun 2020 Oct 14;11(1):5165 Joag V, J Immunol 2021 Mar 1;206(5):931-935 Johnson BA, Nature 2021 Mar;591(7849):293-299 Joyce MG, Cell Rep 2021 Dec 21;37(12):110143 Kaiser R, JCI Insight 2021 Sep 22;6(18):e150862 Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 Kehrer T, Cell Host Microbe 2023 Oct 11;31(10):1668-1684.e12 Khaddaj-Mallat R, Neurobiol Dis 2021 Dec;161():105561 Kim GN, PLoS Pathog 2021 Dec;17(12):e1010092 Kim JW, Front Immunol 2023;14():1271508 Konrath KM, Cell Rep 2022 Feb 1;38(5):110318 Ku MW, bioRxiv 2021 Feb;(): Ku MW, EMBO Mol Med 2021 Dec 7;13(12):e14459 Lee KS, bioRxiv 2022;(): Lee S, Nature 2021 Nov;599(7884):283-289 Lee YJ, Am J Pathol 2023 Jul;193(7):866-882 Li K, mBio 2021 Aug 31;12(4):e0097021 Lin X, bioRxiv 2021 Dec;(): Liu R, bioRxiv 2021 Jan;(): Liu R, Proc Natl Acad Sci U S A 2021 Mar 23;118(12):e2026785118 Li W, Cell Rep 2022 Jan 11;38(2):110210 Lu A, Int J Mol Sci 2024 Feb 8;25(4): Makdasi E, Cell Rep 2021 Sep 7;36(10):109679 Manangeeswaran M, Front Immunol 2022;13():919815 Mao T, bioRxiv 2021 Jun;(): Mao T, bioRxiv 2022;(): Mao T, Proc Natl Acad Sci U S A 2024 Apr 30;121(18):e2319566121 Mao T, Science 2022 Nov 25;378(6622):eabo2523 Martin-Lopez E, eNeuro 2024 Jun;11(6):ENEURO.0106-24.2024 Marx S, bioRxiv 2021 Aug;(): Matchett WE, J Immunol 2021 Jun 30;(): McCray PB Jr, J Virol 2007 Jan;81(2):813-21 Mei M, Proc Natl Acad Sci U S A 2024 May 28;121(22):e2314166121 Mejia OR, bioRxiv 2021 Nov;(): Nagai M, Nat Commun 2023 Jun 30;14(1):3863 Natekar JP, bioRxiv 2022 Apr;(): Noy-Porat T, bioRxiv 2021 Feb;(): Noy-Porat T, iScience 2021 May 21;24(5):102479 Oktay E, Commun Biol 2023 Mar 23;6(1):308 Oladunni FS, Nat Commun 2020 Nov 30;11(1):6122 Olivarria GM, bioRxiv 2021 Nov;(): Oliveira VLS, Front Immunol 2024;15():1378591 Ordonez AA, Commun Biol 2022 Mar 18;5(1):242 Perez P, Front Immunol 2022;13():995235 Perez P, Front Immunol 2023;14():1264323 Puhl AC, bioRxiv 2021;(): Puhl AC, bioRxiv 2021 Dec;(): Qin Z, Theranostics 2021;11(16):8076-8091 Radvak P, bioRxiv 2021 Jun;(): Rathnasinghe R, Emerg Microbes Infect 2020 Oct 17;():1-19 Rizvi ZA, Commun Biol 2023 Sep 13;6(1):935 Roberts LM, J Immunol 2021 Nov 15;207(10):2399-2404 Robertson SJ, bioRxiv 2021 Sep;(): Robertson SJ, Nat Commun 2023 Jul 25;14(1):4481 Rosenfeld R, Nat Commun 2021 Feb 11;12(1):944 Salzer R, bioRxiv 2021 May;(): Scaglione A, bioRxiv 2021 Jun;(): Scaglione A, Front Immunol 2021;12():719077 Schepens B, Sci Transl Med 2021 Nov 24;13(621):eabi7826 Seehusen F, bioRxiv 2021 Apr;(): Shapira T, bioRxiv 2021 May;(): Silvas J, bioRxiv 2021 Mar;(): Sims JJ, bioRxiv 2021 Apr;(): Slamanig S, EBioMedicine 2024 Jun 6;105():105185 Smeyne RJ, bioRxiv 2022 Feb;(): Sohn SY, mBio 2021 Nov 2;():e0275621 Song E, J Exp Med 2021 Mar 1;218(3): Soni DK, bioRxiv 2020 Dec;(): Suberi A, Sci Transl Med 2023 Aug 16;15(709):eabq0603 Subramaniam S, bioRxiv 2021 Aug;(): Sun CP, PLoS Pathog 2021 Aug;17(8):e1009758 Su P, Mol Brain 2022 Aug 9;15(1):71 Suryadevara N, J Clin Invest 2022 Jun 1;132(11):e159062 Syenina A, PLoS Biol 2022 May;20(5):e3001643 Tada T, Cell Rep 2020 Dec 22;33(12):108528 Tada T, Proc Natl Acad Sci U S A 2023 Jun 6;120(23):e2303509120 Tarres-Frexas F, bioRxiv 2021 Aug;(): Tatham L, bioRxiv 2022;(): Turan RD, Sci Rep 2021 Aug 4;11(1):15799 Ullah i, bioRxiv 2021 Mar;(): Ullah I, iScience 2024 Mar 15;27(3):109049 van Bergen J, JCI Insight 2023 Nov 8;8(21): VanBlargan LA, Immunity 2021 Aug 19;(): Van Dyke MC, bioRxiv 2021 May;(): van Huizen M, PLoS Pathog 2024 Mar;20(3):e1012100 Venzon M, bioRxiv 2021 Jul;(): Villadiego J, Nat Neurosci 2023 Feb;26(2):226-238 Walls AC, Cell Rep 2022 Aug 30;40(9):111299 Weiss S, Int J Mol Sci 2023 May 5;24(9): Wenzel J, Nat Neurosci 2021 Nov;24(11):1522-1533 White KM, Science 2021 Feb 26;371(6532):926-931 Winkler ES, bioRxiv 2020 Dec;(): Winkler ES, J Virol 2022 Jan 12;96(1):e0151121 Winkler ES, Nat Immunol 2020 Aug 24;(): Xiao Y, Cell 2021 Dec 9;184(25):6037-6051.e14 Yang JH, Sci Rep 2023 Feb 27;13(1):3303 Yang S, J Med Virol 2022 Aug;94(8):3605-3612 Ying B, bioRxiv 2022 Feb;(): Ying B, Sci Transl Med 2022 Feb 2;14(630):eabm3302 Zhang L, bioRxiv 2022 Mar;(): Zhang L, EMBO Mol Med 2022 Sep 12;():e16109 Zhang X, Cell 2021 Apr 15;184(8):2229-2238.e13 Zheng J, bioRxiv 2020 Aug 10;(): Zheng J, Nature 2021 Jan;589(7843):603-607 Zheng M, Nat Immunol 2021 Jul;22(7):829-838 Zhu C, Nat Commun 2022 Aug 3;13(1):4503 Zumla A, Nat Rev Drug Discov 2016 May;15(5):327-47 |
B6.Cg-Tg(Syn1-ACE2)10Sig/LazarJ | MGI:6401204 | congenic|mutant strain|transgenic | Jia H, Nat Commun 2020 Oct 14;11(1):5165 | J:296535 | SARS-CoV-2_virus | B6.Cg-Tg(Syn1-ACE2)10Sig/LazarJcongenic|mutant strain|transgenic |
Jia H, Nat Commun 2020 Oct 14;11(1):5165 |
|||||||||||
B6(Cg)-Tyrc-2J/J | MGI:2163869 | mutant strain|spontaneous mutation | Scaglione A, Front Immunol 2021;12():719077 | J:335910 | SARS-CoV-2_virus|Treatment|Vaccine | B6(Cg)-Tyrc-2J/Jmutant strain|spontaneous mutation |
Scaglione A, Front Immunol 2021;12():719077 |
|||||||||||
B6/JGpt-Ace2em1Cd/Gpt | MGI:6424280 | coisogenic|endonuclease-mediated mutation|mutant strain | Jia H, Nat Commun 2020 Oct 14;11(1):5165 | J:296535 | SARS-CoV-2_virus | B6/JGpt-Ace2em1Cd/Gptcoisogenic|endonuclease-mediated mutation|mutant strain |
Jia H, Nat Commun 2020 Oct 14;11(1):5165 |
|||||||||||
B6/JGpt-Ace2em1Cflox/Gpt | MGI:6424281 | coisogenic|endonuclease-mediated mutation|mutant strain | Jia H, Nat Commun 2020 Oct 14;11(1):5165 | J:296535 | SARS-CoV-2_virus | B6/JGpt-Ace2em1Cflox/Gptcoisogenic|endonuclease-mediated mutation|mutant strain |
Jia H, Nat Commun 2020 Oct 14;11(1):5165 |
|||||||||||
B6N.129-Ccr9tm1Lov/JmfJ | MGI:5644060 | congenic|mutant strain|targeted mutation | Schafer A, bioRxiv 2021 May;(): Schafer A, mBio 2022 Aug 30;13(4):e0145422 | J:308730 J:327836 | Pathology|SARS-CoV-2-MA_virus|SARS-CoV-2_virus|SARS-CoV-MA_virus|SARS-CoV_virus SARS-CoV-2-MA_virus|SARS-CoV-MA_virus | B6N.129-Ccr9tm1Lov/JmfJcongenic|mutant strain|targeted mutation |
Schafer A, bioRxiv 2021 May;(): Schafer A, mBio 2022 Aug 30;13(4):e0145422 |
|||||||||||
B6N.129-Ceacam1tm2Bcn/J | MGI:5887126 | congenic|mutant strain|targeted mutation | Hemmila E, J Virol 2004 Sep;78(18):10156-65 | J:92376 | Infection|Mouse_Hepatitis_virus | B6N.129-Ceacam1tm2Bcn/Jcongenic|mutant strain|targeted mutation |
Hemmila E, J Virol 2004 Sep;78(18):10156-65 |
|||||||||||
B6N.129S1-Tlr3tm1Flv/J | MGI:4355732 | congenic|mutant strain|targeted mutation | MGI:6433074 | Tlr3tm1Flv | MGI:2653138 | Targeted | Null/knockout | immune system respiratory system | MP:0005387 MP:0005388 | Totura AL, mBio 2015 May 26;6(3):e00638-15 | J:288471 | Infection|SARS-CoV-MA_virus | B6N.129S1-Tlr3tm1Flv/Jcongenic|mutant strain|targeted mutation |
MGI:6433074 | immune system respiratory system |
Totura AL, mBio 2015 May 26;6(3):e00638-15 |
||
B6N.129S2-Casp1tm1Flv/J | MGI:5004932 | congenic|mutant strain|targeted mutation | Duhalde Vega M, Sci Adv 2022 Sep 23;8(38):eabn6545 Wu J, Immunity 2021 Nov 9;54(11):2632-2649.e6 Yang J, Nature 2020 Jul 29;(): | J:331762 J:323769 J:292665 | Mouse_Hepatitis_virus Gene|Pathology SARS-CoV-2_virus|Vaccine | B6N.129S2-Casp1tm1Flv/Jcongenic|mutant strain|targeted mutation |
Duhalde Vega M, Sci Adv 2022 Sep 23;8(38):eabn6545 Wu J, Immunity 2021 Nov 9;54(11):2632-2649.e6 Yang J, Nature 2020 Jul 29;(): |
|||||||||||
B6NCrSlc.Cg-Pla2g2dtm1.1Mhg | MGI:5521186 | congenic|mutant strain|targeted mutation | MGI:5520923 | Pla2g2dtm1.1Mhg | MGI:5517549 | Targeted | Null/knockout | cellular hematopoietic system homeostasis/metabolism immune system mortality/aging | MP:0005384 MP:0005397 MP:0005376 MP:0005387 MP:0010768 | Vijay R, J Exp Med 2015 Oct 19;212(11):1851-68 | J:229035 | Infection|SARS-CoV-MA_virus | B6NCrSlc.Cg-Pla2g2dtm1.1Mhgcongenic|mutant strain|targeted mutation |
MGI:5520923 | cellular hematopoietic system homeostasis/metabolism immune system mortality/aging |
Vijay R, J Exp Med 2015 Oct 19;212(11):1851-68 |
||
B6NTac.129(FVB)-Muc4tm1Unc/Rand | MGI:6423076 | congenic|mutant strain|targeted mutation | MGI:6423102 | Muc4tm1Unc | MGI:6416171 | Targeted | Null/knockout | Coronavirus infectious disease | DOID:0080599 | growth/size/body immune system respiratory system mortality/aging | MP:0005378 MP:0005387 MP:0005388 MP:0010768 | Plante JA, bioRxiv 2020;(): | J:287566 | Infection|SARS-CoV-MA_virus|Sex_bias | B6NTac.129(FVB)-Muc4tm1Unc/Randcongenic|mutant strain|targeted mutation |
MGI:6423102 | growth/size/body immune system respiratory system mortality/aging Coronavirus infectious disease |
Plante JA, bioRxiv 2020;(): |
B6;SJL-Il6ratm1.1Drew/J | MGI:4461009 | mutant stock|targeted mutation | Harb H, Immunity 2021 Apr 22;(): | J:347529 | Infection | B6;SJL-Il6ratm1.1Drew/Jmutant stock|targeted mutation |
Harb H, Immunity 2021 Apr 22;(): |
|||||||||||
B6.SJL-Ptprca Pepcb/BoyJ | MGI:2164701 | congenic|mutant strain | Musiu C, Cell Death Differ 2021 Sep 13;(): | J:313338 | Pathology|SARS-CoV-2_virus | B6.SJL-Ptprca Pepcb/BoyJcongenic|mutant strain |
Musiu C, Cell Death Differ 2021 Sep 13;(): |
|||||||||||
B6;SJL-Tg(KRT18-DPP4)3Pbmj/J | MGI:6455170 | mutant stock|transgenic | Li K, J Infect Dis 2016 Mar 1;213(5):712-22 | J:285467 | Infection|MERS-CoV_virus|Pathology | B6;SJL-Tg(KRT18-DPP4)3Pbmj/Jmutant stock|transgenic |
Li K, J Infect Dis 2016 Mar 1;213(5):712-22 |
|||||||||||
B6;SJL-Tg(SFTPC-DPP4)3Pbmj/J | MGI:6455169 | mutant stock|transgenic | Li K, J Infect Dis 2016 Mar 1;213(5):712-22 | J:285467 | Infection|MERS-CoV_virus|Pathology | B6;SJL-Tg(SFTPC-DPP4)3Pbmj/Jmutant stock|transgenic |
Li K, J Infect Dis 2016 Mar 1;213(5):712-22 |
|||||||||||
BALB/c | MGI:2161072 | strain family | Abdoli A, bioRxiv 2021 Jun;(): Abdoli A, bioRxiv 2022 Feb;(): Agnihothram S, mBio 2014 Mar 25;5(2):e00047-14 Agostini ML, mBio 2018 Mar 6;9(2): Alimohammadi R, bioRxiv 2022 Mar;(): Amanat F, bioRxiv 2021 apr;(): Amanat F, bioRxiv 2021 Aug;(): An Y, bioRxiv 2021 Mar;(): Ao Z, bioRxiv 2021 Dec;(): Baray JC, bioRxiv 2020;(): Barreiro A, bioRxiv 2021 Dec;(): Baxter VK, bioRxiv 2022 Feb;(): Bellier B, bioRxiv 2021 Sep;(): Borriello F, bioRxiv 2021 Sep;(): Brentville VA, bioRxiv 2021 Jun;(): Cantuti-Castelvetri L, Science 2020 Nov 13;370(6518):856-860 Capone S, bioRxiv 2020 Oct;(): Castano-Rodriguez C, mBio 2018 May 22;9(3): Channappanavar R, J Immunol 2017 May 15;198(10):4046-4053 Chapman AP, bioRxiv 2020;(): Chen C, bioRxiv 2022 Feb;(): Chen J, bioRxiv 2021 Nov;(): Chen WH, Hum Vaccin Immunother 2014;10(3):648-58 Chen WH, Vaccine 2020 Nov 3;38(47):7533-7541 Chevillard C, bioRxiv 2021 Sep;(): Choque-Guevara R, bioRxiv 2021 Nov;(): Cohen AA, Science 2021 Feb 12;371(6530):735-741 Compton SR, Virology 1994 Aug 15;203(1):197-201 Conforti A, bioRxiv 2021 Jun;(): Coria LM, bioRxiv 2021 Dec;(): Dai L, Cell 2020 Jun 28;(): Dangi T, bioRxiv 2021 Jun;(): Davenport BJ, bioRxiv 2021 Nov;(): Day CW, Virology 2009 Dec 20;395(2):210-22 Deming D, PLoS Med 2006 Dec;3(12):e525 de Wilde AH, Virus Res 2017 Jan 15;228():7-13 Dey A, bioRxiv 2021 Jan;(): Dietert K, PLoS One 2017;12(11):e0188251 Du L, Nat Commun 2016 Nov 22;7():13473 Du L, PLoS One 2013;8(12):e81587 Elia U, bioRxiv 2020;(): Erasmus JH, Sci Transl Med 2020 Aug 5;12(555): Fehr AR, mBio 2016 Dec 13;7(6): Feng L, Nat Commun 2020 Aug 21;11(1):4207 Fernandez-Castaneda A, bioRxiv 2022;(): Ferrantelli F, bioRxiv 2020 Dec;(): Fett C, J Virol 2013 Jun;87(12):6551-9 Fu D, PLoS Biol 2021 May;19(5):e3001209 Gao J, bioRxiv 2021 Apr;(): Gao Q, Science 2020 Jul 3;369(6499):77-81 Gawish R, bioRxiv 2021 Aug;(): Gonzalez-Dominguez I, bioRxiv 2022 Mar;(): Graham RL, Commun Biol 2018;1():179 Gu H, bioRxiv 2020;(): Gu H, Science 2020 Jul 30;(): Guo X, Immunology 2015 Aug;145(4):476-84 Guo Y, J Biol Chem 2021 Jan 29;():100346 Haabeth OAW, bioRxiv 2021 Apr;(): He Z, bioRxiv 2020;(): Huang Q, Nat Commun 2021 Feb 3;12(1):776 Hua X, JCI Insight 2018 Jun 7;3(11): Hwang M, Immunology 2015 Mar;144(3):374-386 Jangra S, bioRxiv 2020 Oct 23;(): Jiang S, bioRxiv 2021 Aug;(): Joyce MGl Chen WH, bioRxiv 2021 May;(): Kalnin KV, bioRxiv 2020;(): Kandeil A, PLoS One 2020;15(10):e0241471 Kang YF, bioRxiv 2020 Nov;(): Kato H, PLoS One 2019;14(10):e0223684 Khan MS, bioRxiv 2022 May;(): Khanolkar A, J Immunol 2010 Jul 15;185(2):1132-41 Kibler KV, bioRxiv 2021 Dec;(): Kim E, EBioMedicine 2020 May;55():102743 Kim MH, PLoS One 2019;14(7):e0220196 Kobiyama K, bioRxiv 2021 Mar;(): Kozlovskaya L, bioRxiv 2022 Feb;(): Kumaki Y, Antiviral Res 2011 Jan;89(1):75-82 Lan J, PLoS One 2014;9(11):e112602 Lapp SA, bioRxiv 2021 Apr;(): Liang Y, bioRxiv 2021;(): Liao HY, bioRxiv 2021 May;(): Li D, bioRxiv 2021 Jan;(): Li K, mBio 2021 Aug 31;12(4):e0097021 Li L, bioRxiv 2020 Dec;(): Li L, bioRxiv 2021 Jul;(): Lin WS, bioRxiv 2021 Nov;(): Lin X, bioRxiv 2021 Sep;(): Li SW, Sci Rep 2016 May 13;6():25754 Liu H, bioRxiv 2021 Oct;(): Liu S, bioRxiv 2022 Feb;(): Liu WJ, J Immunol 2017 Jan 15;198(2):873-882 Liu X, bioRxiv 2021 Feb;(): Liu Y, bioRxiv 2022 Feb;(): Liu YM, Cell Rep 2020 Aug 11;32(6):108016 Li W, Proc Natl Acad Sci U S A 2020 Nov 24;117(47):29832-29838 Li Y, bioRxiv 2020 Oct;(): Li Z, bioRxiv 2021 Aug;(): Lucchiari MA, J Gen Virol 1991 Jun;72(Pt 6):1317-22 Luo S, bioRxiv 2020;(): Lu RM, bioRxiv 2022 Apr;(): Lu S, bioRxiv 2022 Feb;(): Lv H, Cell Rep 2020 Jun 2;31(9):107725 Mamedov T, bioRxiv 2022 Apr;(): Martinez DR, Science 2021 Aug 27;373(6558):991-998 Mazumder S, bioRxiv 2020 Oct;(): McMillan CL, bioRxiv 2021 May;(): Menachery VD, J Virol 2018 Sep 1;92(17): Mohandas S, Indian J Med Res 2020 May;151(5):479-482 Montagutelli X, bioRxiv 2021 Mar;(): Mudrick HE, bioRxiv 2021 Apr;(): Muruato A, bioRxiv 2021 May;(): Nagai M, bioRxiv 2020 Dec;(): Nanishi E, bioRxiv 2021 May;(): Narayan R, bioRxiv 2022 Feb;(): Nieto-Torres JL, PLoS Pathog 2014 May;10(5):e1004077 Niu J, Antiviral Res 2020 Jan;173():104646 Norheim G, bioRxiv 2020 Dec;(): O'Keefe BR, J Virol 2010 Mar;84(5):2511-21 Park JG, bioRxiv 2021 Jan;(): Paschall AV, bioRxiv 2021;(): Petras M, bioRxiv 2020 Nov;(): Phatarphekar A, bioRxiv 2022 Jan;(): Pitcovski J, bioRxiv 2021 Jun;(): Pollet J, bioRxiv 2020 Nov;(): Pollet J, bioRxiv 2021 Jul;(): Qu L, bioRxiv 2021 Mar;(): Rappaport AR, bioRxiv 2021 Nov;(): Rauch S, bioRxiv 2020 Oct;(): Reed CC, bioRxiv 2021 Aug;(): Roberts A, PLoS Pathog 2007 Jan;3(1):e5 Salah S, bioRxiv 2022 May;(): Schafer A, bioRxiv 2021 Sep;(): Scheiblhofer S, bioRxiv 2021 Feb;(): Seephetdee C, bioRxiv 2022 Mar;(): Sekimukai H, Microbiol Immunol 2020 Jan;64(1):33-51 Seo YB, bioRxiv 2020;(): Seo YB, bioRxiv 2021 Nov;(): Shen L, J Virol 2019 Jun 15;93(12): Shi Y, J Virol 2021 Jan 7;(): Shoemaker RH, bioRxiv 2021 Sep;(): Somogyi E, bioRxiv 2020;(): Staquicini DI, bioRxiv 2021 Mar;(): Stark FC, bioRxiv 2022 Mar;(): Su D, bioRxiv 2021 May;(): Su D, bioRxiv 2022 May;(): Sun CP, PLoS Pathog 2021 Aug;17(8):e1009758 Sun S, bioRxiv 2020 Nov;(): Sun W, bioRxiv 2021 Jul;(): Sun Y, bioRxiv 2021 Jun;(): Sun YJ, bioRxiv 2021 Jan;(): Swart M, bioRxiv 2022 Mar;(): Tostanoski LH, bioRxiv 2021 Jun;(): Tscherne A, bioRxiv 2021 Jan;(): Tseng CT, PLoS One 2012;7(4):e35421 Turan RD, Sci Rep 2021 Aug 4;11(1):15799 Unoh Y, bioRxiv 2022;(): Valdes-Balbin Y, bioRxiv 2021 Feb;(): Vogel AB, bioRxiv 2020 Dec;(): Walls AC, bioRxiv 2021 Mar;(): Walls AC, bioRxiv 2022 Feb;(): Walls AC, Cell Rep 2022 Aug 30;40(9):111299 Wang J, Protein Cell 2020 Aug 4;(): Wen HJ, bioRxiv 2021 Apr;(): Wentworth DE, Emerg Infect Dis 2004 Jul;10(7):1293-6 White KM, Science 2021 Feb 26;371(6532):926-931 Williams RK, Proc Natl Acad Sci U S A 1991 Jul 1;88(13):5533-6 Wong LR, Nature 2022 May;605(7908):146-151 WOng LY, bioRxiv 2021 Apr;(): Wu K, bioRxiv 2021 Apr;(): Wu S, Nat Commun 2020 Aug 14;11(1):4081 Wu Y, bioRxiv 2022 Mar;(): Xu K, bioRxiv 2021 Feb;(): Yang R, EBioMedicine 2020 Jul 21;58():102890 Yang Y, bioRxiv 2021 Jun;(): Yuan Y, bioRxiv 2022 Feb;(): Yu J, bioRxiv 2021 Nov;(): Zabaleta N, bioRxiv 2021 Jan;(): Zang J, bioRxiv 2022 Feb;(): Zhang C, Nat Commun 2021 Jan 11;12(1):264 Zhang H, bioRxiv 2021-08;(): Zhang YN, bioRxiv 2021 Mar;(): Zhao H, Nat Commun 2020 Aug 25;11(1):4252 Zhao H, Sci Rep 2016 Feb 25;6():22008 Zhao S, bioRxiv 2021 May;(): Zhou R, bioRxiv 2021 Oct;(): Zhou Y, Antiviral Res 2015 Apr;116():76-84 Zhuang Z, J Exp Med 2021 Apr 5;218(4): Zhu L, bioRxiv 2020 Nov;(): | J:308653 J:321881 J:288639 J:291893 J:321926 J:304606 J:308583 J:302915 J:316767 J:295383 J:315723 J:321901 J:310112 J:310116 J:308658 J:297122 J:296388 J:291880 J:291593 J:296213 J:321898 J:315718 J:302246 J:302247 J:310119 J:315730 J:302244 J:19444 J:308652 J:316771 J:290261 J:308670 J:315715 J:288585 J:291598 J:286954 J:300435 J:291595 J:291617 J:291630 J:296197 J:291885 J:291863 J:300090 J:321759 J:299089 J:286952 J:308893 J:304619 J:291884 J:308587 J:324918 J:291631 J:295389 J:291864 J:291591 J:309633 J:304646 J:296195 J:302315 J:291882 J:291592 J:296553 J:308668 J:308726 J:296200 J:296974 J:296698 J:292831 J:325024 J:161935 J:316772 J:291871 J:291633 J:302719 J:321880 J:288030 J:291637 J:308711 J:308659 J:308661 J:299105 J:313329 J:298266 J:308625 J:313449 J:310109 J:291621 J:313441 J:321875 J:291594 J:302147 J:321879 J:300093 J:299936 J:296372 J:309204 J:27269 J:295380 J:324952 J:321856 J:291886 J:325040 J:309691 J:296690 J:308889 J:291883 J:291897 J:303189 J:304681 J:308714 J:299071 J:308734 J:321883 J:291590 J:290254 J:298264 J:288029 J:299311 J:311912 J:296700 J:321755 J:308650 J:296705 J:308626 J:302934 J:315716 J:296387 J:308727 J:286408 J:324943 J:310117 J:302702 J:321929 J:291879 J:296069 J:313450 J:291875 J:300108 J:310120 J:296196 J:302940 J:321920 J:308731 J:324975 J:322631 J:298260 J:296709 J:308630 J:308645 J:299309 J:321921 J:308654 J:299308 J:291628 J:309630 J:321771 J:302155 J:298269 J:302930 J:321874 J:328107 J:291872 J:304675 J:286327 J:303457 J:25438 J:331760 J:304684 J:304623 J:300088 J:321907 J:302149 J:291894 J:308671 J:321891 J:313463 J:299310 J:321848 J:300884 J:308588 J:303460 J:300091 J:286403 J:308891 J:313436 J:288032 J:308898 J:298147 | SARS-CoV-2_virus|Vaccine Vaccine|VOC_B.1.1.529_Omicron Infection SARS-CoV-MA_virus|Treatment SARS-CoV-2_virus|VOC_B.1.1.7_Alpha|VOC_B.1.351_Beta SARS-CoV-2_virus|Vaccine|VOC_B.1.1.7_Alpha|VOC_B.1.351_Beta|VOC_P.1_Gamma SARS-CoV-2-MA_virus|Vaccine Infection|SARS-CoV-2_virus Infection|SARS-CoV-MA_virus SARS-CoV-MA_virus|Sex_bias SARS-CoV-2_virus SARS-CoV-2-MA_virus|Treatment|VOC_B.1.1.529_Omicron|VOC_B.1.1.7_Alpha|VOC_B.1.351_Beta|VOC_B.1.617.2_Delta|VOC_P.1_Gamma SARS-CoV_virus|Vaccine Vaccine SARS-CoV-2_virus|Treatment Infection|Mouse_Hepatitis_virus MERS-CoV_virus|SARS-CoV-2_virus|SARS-CoV_virus|Vaccine SARS-CoV-2_virus|SARS-CoV_virus|Vaccine MERS-CoV_virus|SARS-CoV-2_virus|Vaccine Pathology|SARS-CoV-MA_virus MERS-CoV_virus|SARS-CoV-MA_virus|SARS-CoV_virus|Treatment MERS-CoV_virus|Pathology MERS-CoV_virus|Vaccine Pathology|SARS-CoV-2_virus SARS-CoV-MA_virus|Vaccine SARS-CoV-2-MA_virus SARS-CoV-2_virus|Vaccine|Variant|VOC_B.1.351_Beta|VOC_B.1.617.2_Delta|VOC_P.1_Gamma SARS-CoV-MA_virus|SARS-CoV_virus|Vaccine Infection|Pathology|SARS-CoV-2-MA_virus Infection|SARS-CoV-MA_virus|Vaccine Infection|Mouse_Hepatitis_virus|SARS-CoV-MA_virus Mouse_Hepatitis_virus Mouse_Hepatitis_virus|Pathology SARS-CoV-2_virus|Vaccine|VOC_B.1.1.529_Omicron|VOC_B.1.617.2_Delta MERS-CoV-MA_virus|SARS-CoV_virus|Treatment MERS-CoV_virus|SARS-CoV-2_virus|Treatment SARS-CoV_virus SARS-CoV-2_virus|Vaccine|VOC_B.1.617.2_Delta Infection|VOC_B.1.1.529_Omicron SARS-CoV-2-MA_virus|SARS-CoV-2_virus|Treatment SARS-CoV-2-MA_virus|Treatment SARS-CoV-2_virus|Treatment|VOC_B.1.1.529_Omicron Variant HCoV-OC43_virus|Infection|SARS-CoV-2_virus|SARS-CoV_virus SARS-CoV-2_virus|SARS-CoV_virus|Vaccine|VOC_B.1.351_Beta Infection|SARS-CoV-2_virus|VOC_B.1.351_Beta|VOC_P.1_Gamma SARS-CoV-2_virus|SARS-CoV-MA_virus SARS-CoV-MA_virus HCoV-OC43_virus|Infection HCoV-229E_virus|SARS-CoV_virus|Treatment SARS-CoV-2_virus|Vaccine|VOC_B.1.1.7_Alpha|VOC_B.1.351_Beta SARS-CoV-2_virus|Vaccine|VOC_B.1.351_Beta SARS-CoV-2_virus|Vaccine|VOC_B.1.1.529_Omicron|VOC_B.1.1.7_Alpha|VOC_B.1.351_Beta|VOC_B.1.617.2_Delta HCoV-OC43_virus|Treatment SARS-CoV-2_virus|Vaccine|VOC_B.1.351_Beta|VOC_B.1.617.2_Delta Vaccine|VOC_B.1.1.529_Omicron|VOC_B.1.1.7_Alpha|VOC_B.1.351_Beta|VOC_B.1.617.2_Delta|VOC_P.1_Gamma Comorbidity|SARS-CoV-2_virus|Vaccine|VOC_B.1.1.7_Alpha Treatment|VOC_P.1_Gamma Vaccine|Variant SARS-CoV-2_virus|Vaccine|Variant|VOC_B.1.351_Beta SARS-CoV-2-MA_virus|SARS-CoV-2_virus Infection|SARS-CoV_virus SARS-CoV-2_virus|Vaccine|VOC_B.1.1.529_Omicron|VOC_B.1.351_Beta|VOC_B.1.617.2_Delta SARS-CoV-2_virus|Vaccine|VOC_B.1.1.7_Alpha|VOC_B.1.351_Beta|VOC_B.1.617.2_Delta Vaccine|VOC_B.1.617.2_Delta MERS-CoV_virus|SARS-CoV-2_virus|SARS-CoV_virus|Treatment MERS-CoV_virus|SARS-CoV_virus|Treatment Infection|MERS-CoV_virus|SARS-CoV-MA_virus|SARS-CoV_virus|Treatment | BALB/cstrain family |
Abdoli A, bioRxiv 2021 Jun;(): Abdoli A, bioRxiv 2022 Feb;(): Agnihothram S, mBio 2014 Mar 25;5(2):e00047-14 Agostini ML, mBio 2018 Mar 6;9(2): Alimohammadi R, bioRxiv 2022 Mar;(): Amanat F, bioRxiv 2021 apr;(): Amanat F, bioRxiv 2021 Aug;(): An Y, bioRxiv 2021 Mar;(): Ao Z, bioRxiv 2021 Dec;(): Baray JC, bioRxiv 2020;(): Barreiro A, bioRxiv 2021 Dec;(): Baxter VK, bioRxiv 2022 Feb;(): Bellier B, bioRxiv 2021 Sep;(): Borriello F, bioRxiv 2021 Sep;(): Brentville VA, bioRxiv 2021 Jun;(): Cantuti-Castelvetri L, Science 2020 Nov 13;370(6518):856-860 Capone S, bioRxiv 2020 Oct;(): Castano-Rodriguez C, mBio 2018 May 22;9(3): Channappanavar R, J Immunol 2017 May 15;198(10):4046-4053 Chapman AP, bioRxiv 2020;(): Chen C, bioRxiv 2022 Feb;(): Chen J, bioRxiv 2021 Nov;(): Chen WH, Hum Vaccin Immunother 2014;10(3):648-58 Chen WH, Vaccine 2020 Nov 3;38(47):7533-7541 Chevillard C, bioRxiv 2021 Sep;(): Choque-Guevara R, bioRxiv 2021 Nov;(): Cohen AA, Science 2021 Feb 12;371(6530):735-741 Compton SR, Virology 1994 Aug 15;203(1):197-201 Conforti A, bioRxiv 2021 Jun;(): Coria LM, bioRxiv 2021 Dec;(): Dai L, Cell 2020 Jun 28;(): Dangi T, bioRxiv 2021 Jun;(): Davenport BJ, bioRxiv 2021 Nov;(): Day CW, Virology 2009 Dec 20;395(2):210-22 Deming D, PLoS Med 2006 Dec;3(12):e525 de Wilde AH, Virus Res 2017 Jan 15;228():7-13 Dey A, bioRxiv 2021 Jan;(): Dietert K, PLoS One 2017;12(11):e0188251 Du L, Nat Commun 2016 Nov 22;7():13473 Du L, PLoS One 2013;8(12):e81587 Elia U, bioRxiv 2020;(): Erasmus JH, Sci Transl Med 2020 Aug 5;12(555): Fehr AR, mBio 2016 Dec 13;7(6): Feng L, Nat Commun 2020 Aug 21;11(1):4207 Fernandez-Castaneda A, bioRxiv 2022;(): Ferrantelli F, bioRxiv 2020 Dec;(): Fett C, J Virol 2013 Jun;87(12):6551-9 Fu D, PLoS Biol 2021 May;19(5):e3001209 Gao J, bioRxiv 2021 Apr;(): Gao Q, Science 2020 Jul 3;369(6499):77-81 Gawish R, bioRxiv 2021 Aug;(): Gonzalez-Dominguez I, bioRxiv 2022 Mar;(): Graham RL, Commun Biol 2018;1():179 Gu H, bioRxiv 2020;(): Gu H, Science 2020 Jul 30;(): Guo X, Immunology 2015 Aug;145(4):476-84 Guo Y, J Biol Chem 2021 Jan 29;():100346 Haabeth OAW, bioRxiv 2021 Apr;(): He Z, bioRxiv 2020;(): Huang Q, Nat Commun 2021 Feb 3;12(1):776 Hua X, JCI Insight 2018 Jun 7;3(11): Hwang M, Immunology 2015 Mar;144(3):374-386 Jangra S, bioRxiv 2020 Oct 23;(): Jiang S, bioRxiv 2021 Aug;(): Joyce MGl Chen WH, bioRxiv 2021 May;(): Kalnin KV, bioRxiv 2020;(): Kandeil A, PLoS One 2020;15(10):e0241471 Kang YF, bioRxiv 2020 Nov;(): Kato H, PLoS One 2019;14(10):e0223684 Khan MS, bioRxiv 2022 May;(): Khanolkar A, J Immunol 2010 Jul 15;185(2):1132-41 Kibler KV, bioRxiv 2021 Dec;(): Kim E, EBioMedicine 2020 May;55():102743 Kim MH, PLoS One 2019;14(7):e0220196 Kobiyama K, bioRxiv 2021 Mar;(): Kozlovskaya L, bioRxiv 2022 Feb;(): Kumaki Y, Antiviral Res 2011 Jan;89(1):75-82 Lan J, PLoS One 2014;9(11):e112602 Lapp SA, bioRxiv 2021 Apr;(): Liang Y, bioRxiv 2021;(): Liao HY, bioRxiv 2021 May;(): Li D, bioRxiv 2021 Jan;(): Li K, mBio 2021 Aug 31;12(4):e0097021 Li L, bioRxiv 2020 Dec;(): Li L, bioRxiv 2021 Jul;(): Lin WS, bioRxiv 2021 Nov;(): Lin X, bioRxiv 2021 Sep;(): Li SW, Sci Rep 2016 May 13;6():25754 Liu H, bioRxiv 2021 Oct;(): Liu S, bioRxiv 2022 Feb;(): Liu WJ, J Immunol 2017 Jan 15;198(2):873-882 Liu X, bioRxiv 2021 Feb;(): Liu Y, bioRxiv 2022 Feb;(): Liu YM, Cell Rep 2020 Aug 11;32(6):108016 Li W, Proc Natl Acad Sci U S A 2020 Nov 24;117(47):29832-29838 Li Y, bioRxiv 2020 Oct;(): Li Z, bioRxiv 2021 Aug;(): Lucchiari MA, J Gen Virol 1991 Jun;72(Pt 6):1317-22 Luo S, bioRxiv 2020;(): Lu RM, bioRxiv 2022 Apr;(): Lu S, bioRxiv 2022 Feb;(): Lv H, Cell Rep 2020 Jun 2;31(9):107725 Mamedov T, bioRxiv 2022 Apr;(): Martinez DR, Science 2021 Aug 27;373(6558):991-998 Mazumder S, bioRxiv 2020 Oct;(): McMillan CL, bioRxiv 2021 May;(): Menachery VD, J Virol 2018 Sep 1;92(17): Mohandas S, Indian J Med Res 2020 May;151(5):479-482 Montagutelli X, bioRxiv 2021 Mar;(): Mudrick HE, bioRxiv 2021 Apr;(): Muruato A, bioRxiv 2021 May;(): Nagai M, bioRxiv 2020 Dec;(): Nanishi E, bioRxiv 2021 May;(): Narayan R, bioRxiv 2022 Feb;(): Nieto-Torres JL, PLoS Pathog 2014 May;10(5):e1004077 Niu J, Antiviral Res 2020 Jan;173():104646 Norheim G, bioRxiv 2020 Dec;(): O'Keefe BR, J Virol 2010 Mar;84(5):2511-21 Park JG, bioRxiv 2021 Jan;(): Paschall AV, bioRxiv 2021;(): Petras M, bioRxiv 2020 Nov;(): Phatarphekar A, bioRxiv 2022 Jan;(): Pitcovski J, bioRxiv 2021 Jun;(): Pollet J, bioRxiv 2020 Nov;(): Pollet J, bioRxiv 2021 Jul;(): Qu L, bioRxiv 2021 Mar;(): Rappaport AR, bioRxiv 2021 Nov;(): Rauch S, bioRxiv 2020 Oct;(): Reed CC, bioRxiv 2021 Aug;(): Roberts A, PLoS Pathog 2007 Jan;3(1):e5 Salah S, bioRxiv 2022 May;(): Schafer A, bioRxiv 2021 Sep;(): Scheiblhofer S, bioRxiv 2021 Feb;(): Seephetdee C, bioRxiv 2022 Mar;(): Sekimukai H, Microbiol Immunol 2020 Jan;64(1):33-51 Seo YB, bioRxiv 2020;(): Seo YB, bioRxiv 2021 Nov;(): Shen L, J Virol 2019 Jun 15;93(12): Shi Y, J Virol 2021 Jan 7;(): Shoemaker RH, bioRxiv 2021 Sep;(): Somogyi E, bioRxiv 2020;(): Staquicini DI, bioRxiv 2021 Mar;(): Stark FC, bioRxiv 2022 Mar;(): Su D, bioRxiv 2021 May;(): Su D, bioRxiv 2022 May;(): Sun CP, PLoS Pathog 2021 Aug;17(8):e1009758 Sun S, bioRxiv 2020 Nov;(): Sun S, bioRxiv 2020 Nov;(): Sun W, bioRxiv 2021 Jul;(): Sun Y, bioRxiv 2021 Jun;(): Sun YJ, bioRxiv 2021 Jan;(): Swart M, bioRxiv 2022 Mar;(): Tostanoski LH, bioRxiv 2021 Jun;(): Tscherne A, bioRxiv 2021 Jan;(): Tseng CT, PLoS One 2012;7(4):e35421 Turan RD, Sci Rep 2021 Aug 4;11(1):15799 Unoh Y, bioRxiv 2022;(): Valdes-Balbin Y, bioRxiv 2021 Feb;(): Vogel AB, bioRxiv 2020 Dec;(): Walls AC, bioRxiv 2021 Mar;(): Walls AC, bioRxiv 2022 Feb;(): Walls AC, Cell Rep 2022 Aug 30;40(9):111299 Wang J, Protein Cell 2020 Aug 4;(): Wen HJ, bioRxiv 2021 Apr;(): Wentworth DE, Emerg Infect Dis 2004 Jul;10(7):1293-6 White KM, Science 2021 Feb 26;371(6532):926-931 Williams RK, Proc Natl Acad Sci U S A 1991 Jul 1;88(13):5533-6 Wong LR, Nature 2022 May;605(7908):146-151 WOng LY, bioRxiv 2021 Apr;(): Wu K, bioRxiv 2021 Apr;(): Wu S, Nat Commun 2020 Aug 14;11(1):4081 Wu Y, bioRxiv 2022 Mar;(): Xu K, bioRxiv 2021 Feb;(): Yang R, EBioMedicine 2020 Jul 21;58():102890 Yang Y, bioRxiv 2021 Jun;(): Yuan Y, bioRxiv 2022 Feb;(): Yu J, bioRxiv 2021 Nov;(): Zabaleta N, bioRxiv 2021 Jan;(): Zang J, bioRxiv 2022 Feb;(): Zhang C, Nat Commun 2021 Jan 11;12(1):264 Zhang H, bioRxiv 2021-08;(): Zhang YN, bioRxiv 2021 Mar;(): Zhao H, Nat Commun 2020 Aug 25;11(1):4252 Zhao H, Sci Rep 2016 Feb 25;6():22008 Zhao S, bioRxiv 2021 May;(): Zhou R, bioRxiv 2021 Oct;(): Zhou Y, Antiviral Res 2015 Apr;116():76-84 Zhuang Z, J Exp Med 2021 Apr 5;218(4): Zhu L, bioRxiv 2020 Nov;(): |
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BALB/cAnNCr | MGI:2160915 | inbred strain | DeDiego ML, J Virol 2014 Jan;88(2):913-24 Khanolkar A, J Virol 2009 Sep;83(17):8946-56 | J:286180 J:153918 | Pathology|SARS-CoV-MA_virus|Treatment Mouse_Hepatitis_virus|Pathology | BALB/cAnNCrinbred strain |
DeDiego ML, J Virol 2014 Jan;88(2):913-24 Khanolkar A, J Virol 2009 Sep;83(17):8946-56 |
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BALB/cAnNCrl | MGI:2683685 | inbred strain | Barnard DL, Antivir Chem Chemother 2006;17(5):275-84 Brouwer PJM, Cell 2021 Mar 4;184(5):1188-1200.e19 Channappanavar R, J Clin Invest 2019 Jul 29;130():3625-3639 Frieman M, J Virol 2012 Jan;86(2):884-97 Jia W, Emerg Microbes Infect 2019;8(1):760-772 Polak K, bioRxiv 2020 Oct;(): Ying B, bioRxiv 2022 Feb;(): | J:288314 J:303464 J:288107 J:288640 J:286329 J:296676 J:321873 | SARS-CoV_virus|Treatment SARS-CoV-2_virus|Vaccine Infection|MERS-CoV-MA_virus|Treatment Infection|SARS-CoV-MA_virus MERS-CoV-MA_virus|MERS-CoV_virus|Vaccine Vaccine|VOC_B.1.1.529_Omicron | BALB/cAnNCrlinbred strain |
Barnard DL, Antivir Chem Chemother 2006;17(5):275-84 Brouwer PJM, Cell 2021 Mar 4;184(5):1188-1200.e19 Channappanavar R, J Clin Invest 2019 Jul 29;130():3625-3639 Frieman M, J Virol 2012 Jan;86(2):884-97 Jia W, Emerg Microbes Infect 2019;8(1):760-772 Polak K, bioRxiv 2020 Oct;(): Ying B, bioRxiv 2022 Feb;(): |
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BALB/cAnNHsd | MGI:2161082 | inbred strain | Adams LE, Cell Rep 2023 Mar 30;42(4):112326 Bolles M, J Virol 2011 Dec;85(23):12201-15 Leist SR, Cell 2020 Sep 23;(): Menachery VD, Nat Med 2015 Dec;21(12):1508-13 Roberts A, Virus Res 2008 Apr;133(1):20-32 Rockx B, J Virol 2009 Jul;83(14):7062-74 Subbarao K, Trends Microbiol 2006 Jul;14(7):299-303 Wang Y, Invest Ophthalmol Vis Sci 1996 Jan;37(1):250-4 Wang Y, Invest Ophthalmol Vis Sci 2000 Sep;41(10):3011-8 | J:349062 J:288593 J:296277 J:286371 J:286331 J:286406 J:286332 J:36900 J:64200 | SARS-CoV-2-MA_virus|Vaccine SARS-CoV_virus|Vaccine Infection|Pathology|SARS-CoV-2-MA_virus Infection Infection|SARS-CoV_virus|Vaccine Pathology|SARS-CoV_virus SARS-CoV_virus Mouse_Hepatitis_virus Mouse_Hepatitis_virus|Pathology | BALB/cAnNHsdinbred strain |
Adams LE, Cell Rep 2023 Mar 30;42(4):112326 Bolles M, J Virol 2011 Dec;85(23):12201-15 Leist SR, Cell 2020 Sep 23;(): Menachery VD, Nat Med 2015 Dec;21(12):1508-13 Roberts A, Virus Res 2008 Apr;133(1):20-32 Rockx B, J Virol 2009 Jul;83(14):7062-74 Subbarao K, Trends Microbiol 2006 Jul;14(7):299-303 Wang Y, Invest Ophthalmol Vis Sci 1996 Jan;37(1):250-4 Wang Y, Invest Ophthalmol Vis Sci 2000 Sep;41(10):3011-8 |
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BALB/cAnNTac | MGI:6200629 | inbred strain | Adams LE, Cell Rep 2023 Mar 30;42(4):112326 Greenough TC, J Infect Dis 2005 Feb 15;191(4):507-14 Liu R, bioRxiv 2021 Jan;(): Liu R, Proc Natl Acad Sci U S A 2021 Mar 23;118(12):e2026785118 Roberts A, J Virol 2005 May;79(9):5833-8 Subbarao K, J Virol 2004 Apr;78(7):3572-7 | J:349062 J:288263 J:299104 J:303465 J:286301 J:286300 | SARS-CoV-2-MA_virus|Vaccine SARS-CoV_virus|Treatment SARS-CoV-2_virus|Vaccine Pathology|SARS-CoV_virus SARS-CoV_virus | BALB/cAnNTacinbred strain |
Adams LE, Cell Rep 2023 Mar 30;42(4):112326 Greenough TC, J Infect Dis 2005 Feb 15;191(4):507-14 Liu R, bioRxiv 2021 Jan;(): Liu R, Proc Natl Acad Sci U S A 2021 Mar 23;118(12):e2026785118 Roberts A, J Virol 2005 May;79(9):5833-8 Subbarao K, J Virol 2004 Apr;78(7):3572-7 |
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BALB/cBy | MGI:2159790 | inbred strain | Bolles M, J Virol 2011 Dec;85(23):12201-15 | J:288593 | SARS-CoV_virus|Vaccine | BALB/cByinbred strain |
Bolles M, J Virol 2011 Dec;85(23):12201-15 |
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BALB/cByJ | MGI:2159771 | inbred strain | Barthold SW, Lab Anim Sci 1993 Aug;43(4):276-84 Walls AC, Cell Rep 2022 Aug 30;40(9):111299 | J:14457 J:328107 | Infection|Mouse_Hepatitis_virus SARS-CoV-2_virus|Vaccine|Variant|VOC_B.1.351_Beta | BALB/cByJinbred strain |
Barthold SW, Lab Anim Sci 1993 Aug;43(4):276-84 Walls AC, Cell Rep 2022 Aug 30;40(9):111299 |
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BALB/cCrl | MGI:2386653 | inbred strain | Kumaki Y, Antiviral Res 2017 Mar;139():1-12 | J:286953 | SARS-CoV-MA_virus|SARS-CoV_virus|Treatment | BALB/cCrlinbred strain |
Kumaki Y, Antiviral Res 2017 Mar;139():1-12 |
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BALB/cCrSlc | MGI:2161019 | inbred strain | Iwata-Yoshikawa N, J Virol 2014 Aug;88(15):8597-614 Nagai M, mBio 2021 Aug 31;12(4):e0159821 | J:288033 J:313440 | SARS-CoV-MA_virus|Vaccine SARS-CoV-2_virus|Vaccine | BALB/cCrSlcinbred strain |
Iwata-Yoshikawa N, J Virol 2014 Aug;88(15):8597-614 Nagai M, mBio 2021 Aug 31;12(4):e0159821 |
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BALB/cJ | MGI:2159737 | inbred strain | Afkhami S, bioRxiv 2021 Jul;(): Alsoussi WB, J Immunol 2020 Jun 26;(): Arevalo AP, bioRxiv 2020 Nov;(): Corbett KS, Nature 2020 Oct;586(7830):567-571 Dalvie NC, bioRxiv 2021 Mar;(): De Albuquerque N, J Virol 2006 Nov;80(21):10382-94 Gawish R, Elife 2022 Jan 13;11():e74623 Graham JB, iScience 2024 Mar 15;27(3):109103 Hassan AO, Cell 2020 Jun 10;(): Hassan AO, Cell Rep 2021 Jul 27;36(4):109452 Hu Q, bioRxiv 2022 Mar;(): Qu Y, Microbiol Spectr 2023 Jun 15;11(3):e0037823 Rujas E, bioRxiv 2020;(): Slamanig S, EBioMedicine 2024 Jun 6;105():105185 Sourimant J, bioRxiv 2021 May;(): Tummino TA, bioRxiv 2021 Mar;(): Walls AC, Cell 2020 Nov 25;183(5):1367-1382.e17 Wang L, Nat Commun 2015 Jul 28;6():7712 Zost SJ, Nature 2020 Jul 15;(): | J:308640 J:290255 J:296697 J:297398 J:302712 J:288204 J:318828 J:345413 J:290258 J:309629 J:321924 J:357765 J:296183 J:350298 J:308735 J:303456 J:298609 J:291618 J:291899 | SARS-CoV-2_virus|Vaccine|VOC_B.1.1.7_Alpha|VOC_B.1.351_Beta SARS-CoV-2_virus|Treatment Mouse_Hepatitis_virus|Treatment MERS-CoV_virus|SARS-CoV-2_virus|Vaccine SARS-CoV-2_virus|Vaccine Mouse_Hepatitis_virus|Pathology Pathology|SARS-CoV-2-MA_virus SARS-CoV-2-MA_virus Infection|SARS-CoV-2_virus|Treatment SARS-CoV-2_virus|Vaccine|VOC_B.1.1.529_Omicron|VOC_B.1.1.7_Alpha|VOC_B.1.351_Beta|VOC_B.1.617.2_Delta|VOC_P.1_Gamma Gene|Variant|VOC_B.1.1.529_Omicron MERS-CoV_virus|Vaccine SARS-CoV-2-MA_virus|SARS-CoV-2_virus|Treatment | BALB/cJinbred strain |
Afkhami S, bioRxiv 2021 Jul;(): Alsoussi WB, J Immunol 2020 Jun 26;(): Arevalo AP, bioRxiv 2020 Nov;(): Corbett KS, Nature 2020 Oct;586(7830):567-571 Dalvie NC, bioRxiv 2021 Mar;(): De Albuquerque N, J Virol 2006 Nov;80(21):10382-94 Gawish R, Elife 2022 Jan 13;11():e74623 Graham JB, iScience 2024 Mar 15;27(3):109103 Hassan AO, Cell 2020 Jun 10;(): Hassan AO, Cell Rep 2021 Jul 27;36(4):109452 Hu Q, bioRxiv 2022 Mar;(): Qu Y, Microbiol Spectr 2023 Jun 15;11(3):e0037823 Rujas E, bioRxiv 2020;(): Slamanig S, EBioMedicine 2024 Jun 6;105():105185 Sourimant J, bioRxiv 2021 May;(): Tummino TA, bioRxiv 2021 Mar;(): Walls AC, Cell 2020 Nov 25;183(5):1367-1382.e17 Wang L, Nat Commun 2015 Jul 28;6():7712 Zost SJ, Nature 2020 Jul 15;(): |
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BALB/cJRj | MGI:6357755 | inbred strain | Lapuente D, bioRxiv 2021 Aug;(): | J:308581 | SARS-CoV-2_virus|Vaccine | BALB/cJRjinbred strain |
Lapuente D, bioRxiv 2021 Aug;(): |
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(BALB/cJ x B6.Cg-Tg(K18-ACE2)2Prlmn/J)F1/J | MGI:6865665 | F1 hybrid|mutant strain|transgenic | Robertson SJ, Nat Commun 2023 Jul 25;14(1):4481 | J:338561 | Infection|SARS-CoV-2_virus | (BALB/cJ x B6.Cg-Tg(K18-ACE2)2Prlmn/J)F1/JF1 hybrid|mutant strain|transgenic |
Robertson SJ, Nat Commun 2023 Jul 25;14(1):4481 |
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BALB/c-Kctd9em1Beij | MGI:6382781 | coisogenic|endonuclease-mediated mutation|mutant strain | MGI:6382782 | Kctd9em1Beij | MGI:6382731 | Endonuclease-mediated | Null/knockout | hematopoietic system homeostasis/metabolism immune system mortality/aging | MP:0005397 MP:0005376 MP:0005387 MP:0010768 | Zhang X, Front Immunol 2019;10():744 | J:281803 | Mouse_Hepatitis_virus | BALB/c-Kctd9em1Beijcoisogenic|endonuclease-mediated mutation|mutant strain |
MGI:6382782 | hematopoietic system homeostasis/metabolism immune system mortality/aging |
Zhang X, Front Immunol 2019;10():744 |
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BALB/cN | MGI:2161229 | inbred strain | Kovacech B, bioRxiv 2021 Jun;(): | J:308649 | SARS-CoV-2_virus|VOC_B.1.1.7_Alpha|VOC_B.1.351_Beta | BALB/cNinbred strain |
Kovacech B, bioRxiv 2021 Jun;(): |
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BALB/cOlaHsd | MGI:3047778 | inbred strain | DeDiego ML, J Virol 2014 Jan;88(2):913-24 Hachim MY, Front Immunol 2020;11():1372 Jimenez-Guardeno JM, PLoS Pathog 2015 Oct;11(10):e1005215 Rothen DA, bioRxiv 2021 Sep;(): Spencer AJ, bioRxiv 2021 Jan;(): Spencer AJ, bioRxiv 2021 Jun;(): van der Ley PA, bioRxiv 2021 Aug;(): van Doremalen N, Nature 2020 Oct;586(7830):578-582 | J:286180 J:291898 J:291656 J:310118 J:302146 J:308644 J:309194 J:297406 | Pathology|SARS-CoV-MA_virus|Treatment Gene|SARS-CoV-2_virus|SARS-CoV-MA_virus|SARS-CoV_virus SARS-CoV-MA_virus SARS-CoV-2_virus|Vaccine|VOC_B.1.1.7_Alpha|VOC_B.1.351_Beta SARS-CoV-2_virus|Vaccine Vaccine|VOC_B.1.351_Beta|VOC_B.1.617.2_Delta | BALB/cOlaHsdinbred strain |
DeDiego ML, J Virol 2014 Jan;88(2):913-24 Hachim MY, Front Immunol 2020;11():1372 Jimenez-Guardeno JM, PLoS Pathog 2015 Oct;11(10):e1005215 Rothen DA, bioRxiv 2021 Sep;(): Spencer AJ, bioRxiv 2021 Jan;(): Spencer AJ, bioRxiv 2021 Jun;(): van der Ley PA, bioRxiv 2021 Aug;(): van Doremalen N, Nature 2020 Oct;586(7830):578-582 |
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BALB/c-Tg(Rela-luc)31Xen/Tac | MGI:6438428 | coisogenic|mutant strain|transgenic | Samsudin F, bioRxiv 2021 Nov;(): | J:313448 | Pathology|SARS-CoV-2_virus | BALB/c-Tg(Rela-luc)31Xen/Taccoisogenic|mutant strain|transgenic |
Samsudin F, bioRxiv 2021 Nov;(): |
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BXSB.129S2(B6)-Ifnar1tm1Agt/DcrJ | MGI:6159256 | congenic|mutant strain|recombinant inbred (RI)|targeted mutation | Miner JJ, Cell Rep 2020 Nov 3;33(5):108339 | J:300094 | SARS-CoV-2_virus | BXSB.129S2(B6)-Ifnar1tm1Agt/DcrJcongenic|mutant strain|recombinant inbred (RI)|targeted mutation |
Miner JJ, Cell Rep 2020 Nov 3;33(5):108339 |
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C.129P2(B6)-Fcer1gtm1Rav/Tac | MGI:6438695 | congenic|mutant strain|targeted mutation | Adams LE, Cell Rep 2023 Mar 30;42(4):112326 | J:349062 | SARS-CoV-2-MA_virus|Vaccine | C.129P2(B6)-Fcer1gtm1Rav/Taccongenic|mutant strain|targeted mutation |
Adams LE, Cell Rep 2023 Mar 30;42(4):112326 |
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C.129P2-Myd88tm1Aki/Obs | MGI:5577109 | congenic|mutant strain|targeted mutation | Nagai M, mBio 2021 Aug 31;12(4):e0159821 | J:313440 | SARS-CoV-2_virus|Vaccine | C.129P2-Myd88tm1Aki/Obscongenic|mutant strain|targeted mutation |
Nagai M, mBio 2021 Aug 31;12(4):e0159821 |
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C.129S2-Cd1tm1Gru/J | MGI:2174232 | congenic|mutant strain|targeted mutation | Glass WG, J Immunol 2004 Sep 15;173(6):4030-9 | J:92752 | Infection|SARS-CoV_virus | C.129S2-Cd1tm1Gru/Jcongenic|mutant strain|targeted mutation |
Glass WG, J Immunol 2004 Sep 15;173(6):4030-9 |
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C.129S7(B6)-Rag1tm1Mom/J | MGI:2161492 | congenic|mutant strain|targeted mutation | Mao T, bioRxiv 2021 Jun;(): | J:308656 | Treatment|VOC_B.1.1.7_Alpha|VOC_B.1.351_Beta|VOC_P.1_Gamma | C.129S7(B6)-Rag1tm1Mom/Jcongenic|mutant strain|targeted mutation |
Mao T, bioRxiv 2021 Jun;(): |
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C.129X1-Ifngtm1Yiw | MGI:6430486 | congenic|mutant strain|targeted mutation | MGI:6430488 | Ifngtm1Yiw | MGI:3036127 | Targeted | Null/knockout | homeostasis/metabolism immune system liver/biliary system mortality/aging | MP:0005376 MP:0005387 MP:0005370 MP:0010768 | Kyuwa S, Virus Res 2002 Feb 26;83(1-2):169-77 | J:91691 | Infection|Mouse_Hepatitis_virus|Pathology | C.129X1-Ifngtm1Yiwcongenic|mutant strain|targeted mutation |
MGI:6430488 | homeostasis/metabolism immune system liver/biliary system mortality/aging |
Kyuwa S, Virus Res 2002 Feb 26;83(1-2):169-77 |
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C3H/HeJ | MGI:2159741 | inbred strain | Dhanyalayam D, bioRxiv 2021 Sep;(): Khanolkar A, J Immunol 2010 Jul 15;185(2):1132-41 | J:310121 J:161935 | Comorbidity|SARS-CoV-2_virus Mouse_Hepatitis_virus|Pathology | C3H/HeJinbred strain |
Dhanyalayam D, bioRxiv 2021 Sep;(): Khanolkar A, J Immunol 2010 Jul 15;185(2):1132-41 |
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C3H/HeJCr | MGI:2165380 | inbred strain | Hartwig SM, PLoS One 2014;9(3):e90720 Khanolkar A, J Virol 2009 Sep;83(17):8946-56 | J:291635 J:153918 | Mouse_Hepatitis_virus|Pathology | C3H/HeJCrinbred strain |
Hartwig SM, PLoS One 2014;9(3):e90720 Khanolkar A, J Virol 2009 Sep;83(17):8946-56 |
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C3H/HeNCr | MGI:2160592 | inbred strain | Hartwig SM, PLoS One 2014;9(3):e90720 Khanolkar A, J Virol 2009 Sep;83(17):8946-56 | J:291635 J:153918 | Mouse_Hepatitis_virus|Pathology | C3H/HeNCrinbred strain |
Hartwig SM, PLoS One 2014;9(3):e90720 Khanolkar A, J Virol 2009 Sep;83(17):8946-56 |
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C3H/St | MGI:2159861 | inbred strain | De Albuquerque N, J Virol 2006 Nov;80(21):10382-94 | J:288204 | Mouse_Hepatitis_virus|Pathology | C3H/Stinbred strain |
De Albuquerque N, J Virol 2006 Nov;80(21):10382-94 |
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C57BL/10ScNJ | MGI:2165217 | inbred strain | Khanolkar A, J Virol 2009 Sep;83(17):8946-56 Kumaki Y, Antiviral Res 2017 Mar;139():1-12 | J:153918 J:286953 | Mouse_Hepatitis_virus|Pathology SARS-CoV-MA_virus|SARS-CoV_virus|Treatment | C57BL/10ScNJinbred strain |
Khanolkar A, J Virol 2009 Sep;83(17):8946-56 Kumaki Y, Antiviral Res 2017 Mar;139():1-12 |
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C57BL/10SnJ | MGI:2159909 | inbred strain | Greer CD, bioRxiv 2021 Aug;(): Khanolkar A, J Virol 2009 Sep;83(17):8946-56 | J:308745 J:153918 | SARS-CoV-2_virus|Vaccine Mouse_Hepatitis_virus|Pathology | C57BL/10SnJinbred strain |
Greer CD, bioRxiv 2021 Aug;(): Khanolkar A, J Virol 2009 Sep;83(17):8946-56 |
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C57BL/6 | MGI:2159769 | strain family | Ahan RE, bioRxiv 2021 Jul;(): Alimohammadi R, bioRxiv 2022 Mar;(): Almanza G, bioRxiv 2021;(): An Y, bioRxiv 2021 Mar;(): Bleau C, J Virol 2015 Oct;89(19):9896-908 Brechbuhl J, bioRxiv 2021 Mar;(): Brentville VA, bioRxiv 2021 Jun;(): Cao L, bioRxiv 2021;(): Castro JT, bioRxiv 2021 Sep;(): Chandrasekar SS, Vaccines (Basel) 2021 Feb 6;9(2): Channappanavar R, J Immunol 2017 May 15;198(10):4046-4053 Chen J, bioRxiv 2021 Nov;(): Conforti A, bioRxiv 2021 Jun;(): Coria LM, bioRxiv 2021 Dec;(): Counoupas C, bioRxiv 2020 Dec;(): Counoupas C, bioRxiv 2021;(): Dangi T, bioRxiv 2021 Jun;(): Dietert K, PLoS One 2017;12(11):e0188251 Erasmus JH, Sci Transl Med 2020 Aug 5;12(555): Ferrantelli F, bioRxiv 2020 Dec;(): Francis DM, bioRxiv 2021 Aug;(): Gale EC, bioRxiv 2021 Apr;(): Gale EC, bioRxiv 2021 Jul;(): Gawish R, bioRxiv 2021 Aug;(): Gerbre MS, bioRxiv 2021 Nov;(): Glass WG, J Immunol 2004 Apr 1;172(7):4018-25 Gray LT, bioRxiv 2021 May;(): Gu M, bioRxiv 2021 Apr;(): Guo Q, Cell Host Microbe 2021 Feb 10;29(2):222-235.e4 Hachim MY, Front Immunol 2020;11():1372 Hassler L, bioRxiv 2021 Mar;(): Hauser BM, bioRxiv 2021 Mar;(): Hawman DW, bioRxiv 2021 Dec;(): Heer CD, J Biol Chem 2020 Dec 25;295(52):17986-17996 He L, bioRxiv 2020;(): Hennighausen L, Cell Rep 2020 Sep 29;32(13):108199 Huang Q, Nat Commun 2021 Feb 3;12(1):776 Jackson MR, bioRxiv 2021 Mar;(): Jiang S, bioRxiv 2021 Aug;(): Joyce MGl Chen WH, bioRxiv 2021 May;(): Keyaerts E, Antimicrob Agents Chemother 2009 Aug;53(8):3416-21 Khanolkar A, J Immunol 2010 Jul 15;185(2):1132-41 Kim E, EBioMedicine 2020 May;55():102743 Kobiyama K, bioRxiv 2021 Mar;(): Koester ST, PLoS One 2021;16(3):e0248730 Lam JH, bioRxiv 2021 Jan;(): Lapuente D, bioRxiv 2021 Aug;(): Lartey NL, bioRxiv 2021 Apr;(): Lei L, PLoS One 2013;8(4):e61166 Liang Y, Zool Res 2020 Oct 12;():1-29 Li JQ, bioRxiv 2020 Oct;(): Li L, bioRxiv 2021 Jul;(): Liu A, J Pathol 2021 Jan;253(1):17-30 Liu J, bioRxiv 2021 May;(): Long Y, bioRxiv 2021 Apr;(): Luo S, bioRxiv 2020;(): Mohandas S, Indian J Med Res 2020 May;151(5):479-482 Montagutelli X, bioRxiv 2021 Mar;(): Nicolai L, bioRxiv 2021 Jun;(): Niu J, Antiviral Res 2020 Jan;173():104646 Paidi RK, J Immunol 2021 Nov 15;207(10):2521-2533 Pan P, Nat Commun 2021 Aug 2;12(1):4664 Perez-Shibayama C, PLoS One 2013;8(11):e81442 Raha AA, Biosci Rep 2020 Dec 23;40(12): Ryu JK, bioRxiv 2021;(): Ryu S, bioRxiv 2020;(): Sanchez S, bioRxiv 2021 Apr;(): Seephetdee C, bioRxiv 2021 Mar;(): Soni S, PLoS One 2021;16(2):e0247510 Subramani J, bioRxiv 2021 Aug;(): Sun Y, bioRxiv 2021 Jun;(): Tong J, bioRxiv 2021 Feb;(): Tseng CT, PLoS One 2012;7(4):e35421 Volpatti LR, bioRxiv 2021 Apr;(): Vo T, bioRxiv 2020 Nov;(): Wang W, bioRxiv 2020 Dec;(): Wang Y, FASEB J 2021 Mar;35(3):e21419 Wheeler DL, J Clin Invest 2018 Mar 1;128(3):931-943 Wong LR, Nature 2022 May;605(7908):146-151 WOng LY, bioRxiv 2021 Apr;(): Yang C, bioRxiv 2020;(): Yi C, Cell Mol Immunol 2020 Jun;17(6):621-630 Zabaleta N, bioRxiv 2021 Jan;(): Zhuang Z, J Exp Med 2021 Apr 5;218(4): | J:308572 J:321926 J:311920 J:302915 J:291878 J:303458 J:308658 J:311925 J:310123 J:302249 J:291593 J:315718 J:308652 J:316771 J:298265 J:308747 J:308670 J:291595 J:291885 J:299089 J:314179 J:303466 J:308622 J:308587 J:313462 J:88677 J:308736 J:303468 J:308901 J:291898 J:302921 J:302933 J:316766 J:300100 J:295372 J:297407 J:302315 J:302714 J:308668 J:308726 J:288028 J:161935 J:291871 J:302719 J:303461 J:300448 J:308581 J:304620 J:291629 J:296738 J:296674 J:308625 J:301197 J:308729 J:304618 J:295380 J:291897 J:303189 J:308623 J:290254 J:331805 J:313326 J:291632 J:313516 J:311923 J:295364 J:303470 J:302706 J:303459 J:308746 J:308645 J:302154 J:291628 J:304615 J:296710 J:299103 J:309535 J:291614 J:331760 J:304684 J:296070 J:291876 J:299310 J:308898 | SARS-CoV-2_virus|Treatment SARS-CoV-2_virus|Vaccine SARS-CoV-2_virus|VOC_B.1.351_Beta|VOC_B.1.617.2_Delta Infection|Mouse_Hepatitis_virus Gene SARS-CoV-2_virus|Treatment|VOC_B.1.617.2_Delta SARS-CoV-MA_virus|Sex_bias SARS-CoV-2_virus|SARS-CoV_virus|Vaccine MERS-CoV_virus|Pathology SARS-CoV-2_virus|Vaccine|VOC_B.1.351_Beta SARS-CoV-2-MA_virus Mouse_Hepatitis_virus Pathology|SARS-CoV-2_virus Gene|SARS-CoV-2_virus|SARS-CoV-MA_virus|SARS-CoV_virus SARS-CoV-2_virus|Vaccine|VOC_B.1.1.7_Alpha|VOC_B.1.351_Beta Infection|Mouse_Hepatitis_virus|SARS-CoV-2_virus Infection|SARS-CoV-2_virus Pathology Treatment Mouse_Hepatitis_virus|Pathology MERS-CoV_virus|SARS-CoV-2_virus|Vaccine Infection|Pathology|SARS-CoV-2_virus Comorbidity|Gene Vaccine Infection|SARS-CoV-2_virus|VOC_B.1.351_Beta|VOC_P.1_Gamma HCoV-OC43_virus|Infection SARS-CoV-2_virus|Vaccine|VOC_B.1.1.7_Alpha|VOC_B.1.351_Beta|VOC_B.1.617.2_Delta|VOC_P.1_Gamma Comorbidity|SARS-CoV-2_virus|Vaccine|VOC_B.1.1.7_Alpha SARS-CoV_virus|Vaccine Infection SARS-CoV-2-MA_virus|Treatment | C57BL/6strain family |
Ahan RE, bioRxiv 2021 Jul;(): Alimohammadi R, bioRxiv 2022 Mar;(): Almanza G, bioRxiv 2021;(): An Y, bioRxiv 2021 Mar;(): Bleau C, J Virol 2015 Oct;89(19):9896-908 Brechbuhl J, bioRxiv 2021 Mar;(): Brentville VA, bioRxiv 2021 Jun;(): Cao L, bioRxiv 2021;(): Castro JT, bioRxiv 2021 Sep;(): Chandrasekar SS, Vaccines (Basel) 2021 Feb 6;9(2): Channappanavar R, J Immunol 2017 May 15;198(10):4046-4053 Chen J, bioRxiv 2021 Nov;(): Conforti A, bioRxiv 2021 Jun;(): Coria LM, bioRxiv 2021 Dec;(): Counoupas C, bioRxiv 2020 Dec;(): Counoupas C, bioRxiv 2021;(): Dangi T, bioRxiv 2021 Jun;(): Dietert K, PLoS One 2017;12(11):e0188251 Erasmus JH, Sci Transl Med 2020 Aug 5;12(555): Ferrantelli F, bioRxiv 2020 Dec;(): Francis DM, bioRxiv 2021 Aug;(): Gale EC, bioRxiv 2021 Apr;(): Gale EC, bioRxiv 2021 Jul;(): Gawish R, bioRxiv 2021 Aug;(): Gerbre MS, bioRxiv 2021 Nov;(): Glass WG, J Immunol 2004 Apr 1;172(7):4018-25 Gray LT, bioRxiv 2021 May;(): Gu M, bioRxiv 2021 Apr;(): Guo Q, Cell Host Microbe 2021 Feb 10;29(2):222-235.e4 Hachim MY, Front Immunol 2020;11():1372 Hassler L, bioRxiv 2021 Mar;(): Hauser BM, bioRxiv 2021 Mar;(): Hawman DW, bioRxiv 2021 Dec;(): Heer CD, J Biol Chem 2020 Dec 25;295(52):17986-17996 He L, bioRxiv 2020;(): Hennighausen L, Cell Rep 2020 Sep 29;32(13):108199 Huang Q, Nat Commun 2021 Feb 3;12(1):776 Jackson MR, bioRxiv 2021 Mar;(): Jiang S, bioRxiv 2021 Aug;(): Joyce MGl Chen WH, bioRxiv 2021 May;(): Keyaerts E, Antimicrob Agents Chemother 2009 Aug;53(8):3416-21 Khanolkar A, J Immunol 2010 Jul 15;185(2):1132-41 Kim E, EBioMedicine 2020 May;55():102743 Kobiyama K, bioRxiv 2021 Mar;(): Koester ST, PLoS One 2021;16(3):e0248730 Lam JH, bioRxiv 2021 Jan;(): Lapuente D, bioRxiv 2021 Aug;(): Lartey NL, bioRxiv 2021 Apr;(): Lei L, PLoS One 2013;8(4):e61166 Liang Y, Zool Res 2020 Oct 12;():1-29 Li JQ, bioRxiv 2020 Oct;(): Li L, bioRxiv 2021 Jul;(): Liu A, J Pathol 2021 Jan;253(1):17-30 Liu J, bioRxiv 2021 May;(): Long Y, bioRxiv 2021 Apr;(): Luo S, bioRxiv 2020;(): Mohandas S, Indian J Med Res 2020 May;151(5):479-482 Montagutelli X, bioRxiv 2021 Mar;(): Nicolai L, bioRxiv 2021 Jun;(): Niu J, Antiviral Res 2020 Jan;173():104646 Paidi RK, J Immunol 2021 Nov 15;207(10):2521-2533 Pan P, Nat Commun 2021 Aug 2;12(1):4664 Perez-Shibayama C, PLoS One 2013;8(11):e81442 Raha AA, Biosci Rep 2020 Dec 23;40(12): Ryu JK, bioRxiv 2021;(): Ryu S, bioRxiv 2020;(): Sanchez S, bioRxiv 2021 Apr;(): Seephetdee C, bioRxiv 2021 Mar;(): Soni S, PLoS One 2021;16(2):e0247510 Subramani J, bioRxiv 2021 Aug;(): Sun Y, bioRxiv 2021 Jun;(): Tong J, bioRxiv 2021 Feb;(): Tseng CT, PLoS One 2012;7(4):e35421 Volpatti LR, bioRxiv 2021 Apr;(): Vo T, bioRxiv 2020 Nov;(): Wang W, bioRxiv 2020 Dec;(): Wang Y, FASEB J 2021 Mar;35(3):e21419 Wheeler DL, J Clin Invest 2018 Mar 1;128(3):931-943 Wong LR, Nature 2022 May;605(7908):146-151 WOng LY, bioRxiv 2021 Apr;(): Yang C, bioRxiv 2020;(): Yi C, Cell Mol Immunol 2020 Jun;17(6):621-630 Zabaleta N, bioRxiv 2021 Jan;(): Zhuang Z, J Exp Med 2021 Apr 5;218(4): |
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C57BL/6-Ace2em1(ACE2)Yowa | MGI:6431338 | coisogenic|endonuclease-mediated mutation|mutant strain | MGI:6431340 | Ace2em1(ACE2)Yowa | MGI:6431336 | Endonuclease-mediated | Humanized sequence|Null/knockout|Reporter | COVID-19 | DOID:0080600 | cardiovascular system homeostasis/metabolism immune system respiratory system | MP:0005385 MP:0005376 MP:0005387 MP:0005388 | Sun SH, Cell Host Microbe 2020;20():1-10 | J:288243 | Infection|Pathology|SARS-CoV-2_virus | C57BL/6-Ace2em1(ACE2)Yowacoisogenic|endonuclease-mediated mutation|mutant strain |
MGI:6431340 | cardiovascular system homeostasis/metabolism immune system respiratory system COVID-19 |
Sun SH, Cell Host Microbe 2020;20():1-10 |
C57BL/6(FVB)-Ceacam1tm1.1Fta | MGI:5496838 | mutant strain|targeted mutation | MGI:5496535 | Ceacam1tm1.1Fta | MGI:5496530 | Targeted | Inserted expressed sequence | immune system mortality/aging | MP:0005387 MP:0010768 | Hirai A, J Virol 2010 Jul;84(13):6654-66 | J:198335 | Infection|Mouse_Hepatitis_virus | C57BL/6(FVB)-Ceacam1tm1.1Ftamutant strain|targeted mutation |
MGI:5496535 | immune system mortality/aging |
Hirai A, J Virol 2010 Jul;84(13):6654-66 |
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C57BL/6-Gt(ROSA)26Sorem1(DPP4)Yowa | MGI:6403445 | coisogenic|endonuclease-mediated mutation|mutant strain | MGI:6403447 | Gt(ROSA)26Sorem1(DPP4)Yowa | MGI:6403442 | Endonuclease-mediated | Humanized sequence|Inserted expressed sequence|Reporter | Middle East respiratory syndrome | DOID:0080642 | immune system nervous system | MP:0005387 MP:0003631 | Fan C, Viruses 2018 Aug 23;10(9): | J:279060 | Infection|MERS-CoV_virus|Pathology|Treatment | C57BL/6-Gt(ROSA)26Sorem1(DPP4)Yowacoisogenic|endonuclease-mediated mutation|mutant strain |
MGI:6403447 | immune system nervous system Middle East respiratory syndrome |
Fan C, Viruses 2018 Aug 23;10(9): |
C57BL/6-Irf5tm1Ppr/J | MGI:5291921 | coisogenic|mutant strain|targeted mutation | Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 | J:296686 | Pathology|SARS-CoV-2_virus|Treatment | C57BL/6-Irf5tm1Ppr/Jcoisogenic|mutant strain|targeted mutation |
Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 |
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C57BL/6J | MGI:3028467 | inbred strain | MGI:2166311 | cardiovascular system endocrine/exocrine glands homeostasis/metabolism immune system muscle nervous system | MP:0005385 MP:0005379 MP:0005376 MP:0005387 MP:0005369 MP:0003631 | Afkhami S, bioRxiv 2021 Jul;(): Alsoussi WB, J Immunol 2020 Jun 26;(): Anand G, bioRxiv 2020 Dec;(): Benard A, Nat Commun 2021 Feb 18;12(1):1112 Biering SB, bioRxiv 2021 Dec;(): Bilinska K, bioRxiv 2021 Apr;(): Borriello F, bioRxiv 2021 Sep;(): Brady M, bioRxiv 2021 Aug;(): Brooks SD, bioRxiv 2021;(): Cao X, bioRxiv 2020 Dec;(): Chaparian RR, bioRxiv 2021 Apr;(): Chen JS, J Virol 2021 Jan 13;(): Chen Y, bioRxiv 2021 Nov;(): Chong Z, bioRxiv 2022;(): Chong Z, Cell Rep 2022 May 10;39(6):110799 Colunga Biancatelli R, Am J Physiol Lung Cell Mol Physiol 2021 Jun;(): Corbett KS, Nature 2020 Oct;586(7830):567-571 Das Sarma J, J Virol 2000 Oct;74(19):9206-13 De Albuquerque N, J Virol 2006 Nov;80(21):10382-94 Deng Q, bioRxiv 2020;(): Deng X, J Virol 2014 Oct 15;88(20):11886-98 dos Santos Pereira Andrade AC, bioRxiv 2021 May;(): Eldi P, bioRxiv 2021 Sep;(): Gawish R, Elife 2022 Jan 13;11():e74623 Geng T, bioRxiv 2021 Jun;(): Graham JB, iScience 2024 Mar 15;27(3):109103 Gralinski LE, mBio 2013 Aug 6;4(4): Gralinski LE, PLoS Genet 2015 Oct;11(10):e1005504 Hachim MY, Front Immunol 2020;11():1372 Han K, Am J Respir Cell Mol Biol 2021 Jan;64(1):79-88 Houtman JJ, J Neurovirol 1996 APR;2(2):101-110 Jia L, bioRxiv 2022 Feb;(): Joag V, J Immunol 2021 Mar 1;206(5):931-935 Josset L, RNA Biol 2014;11(7):875-90 Khaddaj-Mallat R, bioRxiv 2021 May;(): Kim E, Proc Natl Acad Sci U S A 2021 Aug 24;118(34):e2102435118 Kim TY, bioRxiv 2020 Dec;(): King RG, bioRxiv 2020;(): Kumaki Y, Antiviral Res 2017 Mar;139():1-12 Leist SR, Cell 2020 Sep 23;(): Li S, JCI Insight 2021 Jan 25;6(2): Madar-Balakirski N, bioRxiv 2021 Jul;(): Mandal P, PLoS One 2021;16(7):e0246270 Ngo VL, Cell Host Microbe 2024 Jan 23;(): Pewe L, J Virol 1997 Oct;71(10):7640-7 Radvak P, bioRxiv 2021 Jun;(): Roberts A, Virus Res 2008 Apr;133(1):20-32 Salvi V, bioRxiv 2021 Apr;(): Salvi V, JCI Insight 2021 Sep 22;6(18):e150542 Salzer R, bioRxiv 2021 May;(): Sarver DC, Biochem Biophys Res Commun 2021 Jan 29;538():92-96 Satta S, Theranostics 2022;12(6):2639-2657 Schafer A, mBio 2022 Aug 30;13(4):e0145422 Sepe S, bioRxiv 2021 Jun;(): Sheahan TP, Sci Transl Med 2020 Apr 29;12(541): Shirato K, bioRxiv 2021 Jul;(): Sims JJ, bioRxiv 2021 Apr;(): Subbarao K, Trends Microbiol 2006 Jul;14(7):299-303 Sun CP, PLoS Pathog 2021 Aug;17(8):e1009758 Szurgot I, Sci Rep 2021 Feb 4;11(1):3125 Tsai SJ, bioRxiv 2020 Nov;(): Ullah I, iScience 2024 Mar 15;27(3):109049 Vanderheiden A, bioRxiv 2021 May;(): Vanderheiden A, mBio 2021 Nov 9;():e0274921 Wang H, bioRxiv 2021 Jul;(): Wang J, Protein Cell 2020 Aug 4;(): White KM, Science 2021 Feb 26;371(6532):926-931 Xiong H, G3 (Bethesda) 2014 Jun 5;4(8):1429-44 Xu H, bioRxiv 2020;(): Zhou B, Nature 2021 Apr;592(7852):122-127 Zhuang X, iScience 2021 Oct 22;24(10):103144 | J:308640 J:290255 J:298270 J:303473 J:316773 J:304622 J:310116 J:308577 J:311924 J:298259 J:308713 J:300110 J:315729 J:321761 J:325089 J:309512 J:297398 J:64499 J:288204 J:296182 J:214600 J:308662 J:310113 J:318828 J:308624 J:345413 J:288556 J:268979 J:291898 J:331824 J:33974 J:321887 J:303898 J:276026 J:308715 J:313327 J:299070 J:296068 J:286953 J:296277 J:302826 J:308635 J:308899 J:345954 J:42952 J:308643 J:286331 J:304651 J:313336 J:308749 J:309632 J:331825 J:327836 J:309195 J:286320 J:308576 J:304613 J:286332 J:322631 J:302250 J:296707 J:348954 J:308718 J:317454 J:308641 J:291872 J:303457 J:276183 J:295377 J:305777 J:341699 | SARS-CoV-2_virus|Vaccine|VOC_B.1.1.7_Alpha|VOC_B.1.351_Beta SARS-CoV-2_virus|Treatment Pathology|SARS-CoV-2_virus SARS-CoV-2_virus Gene SARS-CoV-2_virus|Vaccine Infection|SARS-CoV-2_virus SARS-CoV-2_virus|Treatment|VOC_B.1.1.529_Omicron|VOC_B.1.351_Beta MERS-CoV_virus|SARS-CoV-2_virus|Vaccine Mouse_Hepatitis_virus|Pathology SARS-CoV-2_virus|Sex_bias Mouse_Hepatitis_virus Pathology|SARS-CoV-2-MA_virus SARS-CoV-2-MA_virus Infection|Pathology|SARS-CoV-MA_virus Infection|SARS-CoV-MA_virus Gene|SARS-CoV-2_virus|SARS-CoV-MA_virus|SARS-CoV_virus Infection|Pathology|SARS-CoV-2_virus SARS-CoV-2_virus|Vaccine|VOC_B.1.1.529_Omicron SARS-CoV-MA_virus SARS-CoV-MA_virus|SARS-CoV_virus|Treatment Infection|Pathology|SARS-CoV-2-MA_virus Infection|MERS-CoV-MA_virus Pathology|SARS-CoV-2_virus|VOC_B.1.1.7_Alpha|VOC_B.1.351_Beta Infection|SARS-CoV_virus|Vaccine Comorbidity SARS-CoV-2_virus|Variant SARS-CoV-2-MA_virus|SARS-CoV-MA_virus Comorbidity|Gene MERS-CoV_virus|SARS-CoV-2_virus|SARS-CoV-MA_virus|SARS-CoV_virus|Treatment SARS-CoV_virus SARS-CoV-2_virus|Treatment|VOC_B.1.1.529_Omicron|VOC_B.1.617.2_Delta SARS-CoV-2-MA_virus|SARS-CoV-2_virus|VOC_B.1.351_Beta Infection|SARS-CoV-2-MA_virus|VOC_B.1.351_Beta SARS-CoV-2-MA_virus|SARS-CoV-2_virus Treatment | C57BL/6Jinbred strain |
MGI:2166311 | cardiovascular system endocrine/exocrine glands homeostasis/metabolism immune system muscle nervous system |
Afkhami S, bioRxiv 2021 Jul;(): Alsoussi WB, J Immunol 2020 Jun 26;(): Anand G, bioRxiv 2020 Dec;(): Benard A, Nat Commun 2021 Feb 18;12(1):1112 Biering SB, bioRxiv 2021 Dec;(): Bilinska K, bioRxiv 2021 Apr;(): Borriello F, bioRxiv 2021 Sep;(): Brady M, bioRxiv 2021 Aug;(): Brooks SD, bioRxiv 2021;(): Cao X, bioRxiv 2020 Dec;(): Chaparian RR, bioRxiv 2021 Apr;(): Chen JS, J Virol 2021 Jan 13;(): Chen Y, bioRxiv 2021 Nov;(): Chong Z, bioRxiv 2022;(): Chong Z, Cell Rep 2022 May 10;39(6):110799 Colunga Biancatelli R, Am J Physiol Lung Cell Mol Physiol 2021 Jun;(): Corbett KS, Nature 2020 Oct;586(7830):567-571 Das Sarma J, J Virol 2000 Oct;74(19):9206-13 De Albuquerque N, J Virol 2006 Nov;80(21):10382-94 Deng Q, bioRxiv 2020;(): Deng X, J Virol 2014 Oct 15;88(20):11886-98 dos Santos Pereira Andrade AC, bioRxiv 2021 May;(): Eldi P, bioRxiv 2021 Sep;(): Gawish R, Elife 2022 Jan 13;11():e74623 Geng T, bioRxiv 2021 Jun;(): Graham JB, iScience 2024 Mar 15;27(3):109103 Gralinski LE, mBio 2013 Aug 6;4(4): Gralinski LE, PLoS Genet 2015 Oct;11(10):e1005504 Hachim MY, Front Immunol 2020;11():1372 Han K, Am J Respir Cell Mol Biol 2021 Jan;64(1):79-88 Houtman JJ, J Neurovirol 1996 APR;2(2):101-110 Jia L, bioRxiv 2022 Feb;(): Joag V, J Immunol 2021 Mar 1;206(5):931-935 Josset L, RNA Biol 2014;11(7):875-90 Khaddaj-Mallat R, bioRxiv 2021 May;(): Kim E, Proc Natl Acad Sci U S A 2021 Aug 24;118(34):e2102435118 Kim TY, bioRxiv 2020 Dec;(): King RG, bioRxiv 2020;(): Kumaki Y, Antiviral Res 2017 Mar;139():1-12 Leist SR, Cell 2020 Sep 23;(): Li S, JCI Insight 2021 Jan 25;6(2): Madar-Balakirski N, bioRxiv 2021 Jul;(): Mandal P, PLoS One 2021;16(7):e0246270 Ngo VL, Cell Host Microbe 2024 Jan 23;(): Pewe L, J Virol 1997 Oct;71(10):7640-7 Radvak P, bioRxiv 2021 Jun;(): Roberts A, Virus Res 2008 Apr;133(1):20-32 Salvi V, bioRxiv 2021 Apr;(): Salvi V, JCI Insight 2021 Sep 22;6(18):e150542 Salzer R, bioRxiv 2021 May;(): Sarver DC, Biochem Biophys Res Commun 2021 Jan 29;538():92-96 Satta S, Theranostics 2022;12(6):2639-2657 Schafer A, mBio 2022 Aug 30;13(4):e0145422 Sepe S, bioRxiv 2021 Jun;(): Sheahan TP, Sci Transl Med 2020 Apr 29;12(541): Shirato K, bioRxiv 2021 Jul;(): Sims JJ, bioRxiv 2021 Apr;(): Subbarao K, Trends Microbiol 2006 Jul;14(7):299-303 Sun CP, PLoS Pathog 2021 Aug;17(8):e1009758 Szurgot I, Sci Rep 2021 Feb 4;11(1):3125 Tsai SJ, bioRxiv 2020 Nov;(): Ullah I, iScience 2024 Mar 15;27(3):109049 Vanderheiden A, bioRxiv 2021 May;(): Vanderheiden A, mBio 2021 Nov 9;():e0274921 Wang H, bioRxiv 2021 Jul;(): Wang J, Protein Cell 2020 Aug 4;(): White KM, Science 2021 Feb 26;371(6532):926-931 Xiong H, G3 (Bethesda) 2014 Jun 5;4(8):1429-44 Xu H, bioRxiv 2020;(): Zhou B, Nature 2021 Apr;592(7852):122-127 Zhuang X, iScience 2021 Oct 22;24(10):103144 |
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C57BL/6J-Ace2em1Cya/Cya | MGI:6500741 | coisogenic|endonuclease-mediated mutation|mutant strain | MGI:6500742 | Ace2em1Cya | MGI:6500740 | Endonuclease-mediated | Null/knockout | cellular digestive/alimentary system growth/size/body homeostasis/metabolism immune system | MP:0005384 MP:0005381 MP:0005378 MP:0005376 MP:0005387 | Yu W, Biochem Biophys Res Commun 2020 Dec 17;533(4):1276-1282 | J:299383 | Gene | C57BL/6J-Ace2em1Cya/Cyacoisogenic|endonuclease-mediated mutation|mutant strain |
MGI:6500742 | cellular digestive/alimentary system growth/size/body homeostasis/metabolism immune system |
Yu W, Biochem Biophys Res Commun 2020 Dec 17;533(4):1276-1282 |
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C57BL/6J-Ace2em1Guru/Mmjax | MGI:6763024 | coisogenic|endonuclease-mediated mutation|mutant strain | Gurumurthy CB, Nat Protoc 2020 Dec;15(12):3777-3787 | J:298750 | SARS-CoV-2_virus | C57BL/6J-Ace2em1Guru/Mmjaxcoisogenic|endonuclease-mediated mutation|mutant strain |
Gurumurthy CB, Nat Protoc 2020 Dec;15(12):3777-3787 |
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C57BL/6J-Ace2em2Guru/Mmjax | MGI:6763026 | coisogenic|endonuclease-mediated mutation|mutant strain | Gurumurthy CB, Nat Protoc 2020 Dec;15(12):3777-3787 | J:298750 | SARS-CoV-2_virus | C57BL/6J-Ace2em2Guru/Mmjaxcoisogenic|endonuclease-mediated mutation|mutant strain |
Gurumurthy CB, Nat Protoc 2020 Dec;15(12):3777-3787 |
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C57BL/6J-Dpp4em1Rba | MGI:6400424 | coisogenic|endonuclease-mediated mutation|mutant strain | MGI:6400425 MGI:6400427 | Dpp4em1Rba | MGI:6400423 | Endonuclease-mediated | Humanized sequence | Middle East respiratory syndrome | DOID:0080642 | cardiovascular system growth/size/body hematopoietic system homeostasis/metabolism immune system respiratory system mortality/aging | MP:0005385 MP:0005378 MP:0005397 MP:0005376 MP:0005387 MP:0005388 MP:0010768 | Cockrell AS, Nat Microbiol 2016 Nov 28;2():16226 Leist SR, PLoS One 2019;14(7):e0220126 Sheahan TP, Sci Transl Med 2020 Apr 29;12(541): | J:279834 J:279723 J:286320 | MERS-CoV_virus MERS-CoV_virus|Pathology MERS-CoV_virus|SARS-CoV-2_virus|SARS-CoV-MA_virus|SARS-CoV_virus|Treatment | C57BL/6J-Dpp4em1Rbacoisogenic|endonuclease-mediated mutation|mutant strain |
MGI:6400425 MGI:6400427 | cardiovascular system growth/size/body hematopoietic system homeostasis/metabolism immune system respiratory system mortality/aging Middle East respiratory syndrome |
Cockrell AS, Nat Microbiol 2016 Nov 28;2():16226 Leist SR, PLoS One 2019;14(7):e0220126 Sheahan TP, Sci Transl Med 2020 Apr 29;12(541): |
C57BL/6JJcl | MGI:3055581 | inbred strain | Nagai M, Nat Commun 2023 Jun 30;14(1):3863 | J:337953 | SARS-CoV-2_virus|VOC_B.1.1.7_Alpha | C57BL/6JJclinbred strain |
Nagai M, Nat Commun 2023 Jun 30;14(1):3863 |
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C57BL/6J-Lystbg-J/J | MGI:2163994 | coisogenic|mutant strain|spontaneous mutation | Glass WG, J Immunol 2004 Sep 15;173(6):4030-9 | J:92752 | Infection|SARS-CoV_virus | C57BL/6J-Lystbg-J/Jcoisogenic|mutant strain|spontaneous mutation |
Glass WG, J Immunol 2004 Sep 15;173(6):4030-9 |
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C57BL/6J-Sting1gt/J | MGI:5292744 | chemically induced mutation|coisogenic|mutant strain | Yang J, Nature 2020 Jul 29;(): | J:292665 | SARS-CoV-2_virus|Vaccine | C57BL/6J-Sting1gt/Jchemically induced mutation|coisogenic|mutant strain |
Yang J, Nature 2020 Jul 29;(): |
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C57BL/6J-Tg(CAG-ACE2)GT5-027Cyt/J | MGI:6711187 | coisogenic|mutant strain|transgenic | Tsai C-Y, bioRxiv 2021;(): | J:305559 | SARS-CoV-2_virus | C57BL/6J-Tg(CAG-ACE2)GT5-027Cyt/Jcoisogenic|mutant strain|transgenic |
Tsai C-Y, bioRxiv 2021;(): |
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C57BL/6J-Ticam1Lps2/J | MGI:3051113 | chemically induced mutation|coisogenic|mutant strain | MGI:5520919 | Ticam1Lps2 | MGI:2679794 | Chemically induced (ENU) | Not Specified | cardiovascular system hematopoietic system homeostasis/metabolism immune system respiratory system mortality/aging | MP:0005385 MP:0005397 MP:0005376 MP:0005387 MP:0005388 MP:0010768 | Totura AL, mBio 2015 May 26;6(3):e00638-15 | J:288471 | Infection|SARS-CoV-MA_virus | C57BL/6J-Ticam1Lps2/Jchemically induced mutation|coisogenic|mutant strain |
MGI:5520919 | cardiovascular system hematopoietic system homeostasis/metabolism immune system respiratory system mortality/aging |
Totura AL, mBio 2015 May 26;6(3):e00638-15 |
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(C57BL/6J x C3H/HeJ)F1/J | MGI:5654213 | F1 hybrid | Corbett KS, Nature 2020 Oct;586(7830):567-571 | J:297398 | MERS-CoV_virus|SARS-CoV-2_virus|Vaccine | (C57BL/6J x C3H/HeJ)F1/JF1 hybrid |
Corbett KS, Nature 2020 Oct;586(7830):567-571 |
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C57BL/6-Mcph1Tg(HLA-A2.1)1Enge/J | MGI:2164434 | mutant strain|transgenic | Carter B, bioRxiv 2021 May;(): | J:308712 | SARS-CoV-2_virus|Vaccine | C57BL/6-Mcph1Tg(HLA-A2.1)1Enge/Jmutant strain|transgenic |
Carter B, bioRxiv 2021 May;(): |
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C57BL/6N | MGI:2159965 | inbred strain | Cantuti-Castelvetri L, Science 2020 Nov 13;370(6518):856-860 Rai P, bioRxiv 2021 Jun;(): | J:297122 J:308665 | Infection|SARS-CoV-2_virus Pathology|SARS-CoV-2_virus | C57BL/6Ninbred strain |
Cantuti-Castelvetri L, Science 2020 Nov 13;370(6518):856-860 Rai P, bioRxiv 2021 Jun;(): |
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C57BL/6NCr | MGI:2160593 | inbred strain | Fang Z, bioRxiv 2022 Mar;(): Khanolkar A, J Virol 2009 Sep;83(17):8946-56 | J:324933 J:153918 | Vaccine|VOC_B.1.1.529_Omicron Mouse_Hepatitis_virus|Pathology | C57BL/6NCrinbred strain |
Fang Z, bioRxiv 2022 Mar;(): Khanolkar A, J Virol 2009 Sep;83(17):8946-56 |
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C57BL/6NCrl | MGI:2683688 | inbred strain | De Gasparo R, bioRxiv 2021 Jan;(): Rujas E, bioRxiv 2020;(): Sariol A, Proc Natl Acad Sci U S A 2020 Sep 29;117(39):24464-24474 | J:300432 J:296183 J:298608 | SARS-CoV-2_virus|Treatment Mouse_Hepatitis_virus | C57BL/6NCrlinbred strain |
De Gasparo R, bioRxiv 2021 Jan;(): Rujas E, bioRxiv 2020;(): Sariol A, Proc Natl Acad Sci U S A 2020 Sep 29;117(39):24464-24474 |
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C57BL/6NCrSlc | MGI:5295404 | inbred strain | Nishikawa T, bioRxiv 2021 Jan;(): | J:300443 | SARS-CoV-2-MA_virus|Vaccine | C57BL/6NCrSlcinbred strain |
Nishikawa T, bioRxiv 2021 Jan;(): |
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C57BL/6N-Gsdmdem4Fcw/J | MGI:6196335 | coisogenic|endonuclease-mediated mutation|mutant strain | Wu J, Immunity 2021 Nov 9;54(11):2632-2649.e6 | J:323769 | Gene|Pathology | C57BL/6N-Gsdmdem4Fcw/Jcoisogenic|endonuclease-mediated mutation|mutant strain |
Wu J, Immunity 2021 Nov 9;54(11):2632-2649.e6 |
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C57BL/6NJ | MGI:3056279 | inbred strain | Hachim MY, Front Immunol 2020;11():1372 Schafer A, bioRxiv 2021 May;(): Schafer A, mBio 2022 Aug 30;13(4):e0145422 | J:291898 J:308730 J:327836 | Gene|SARS-CoV-2_virus|SARS-CoV-MA_virus|SARS-CoV_virus Pathology|SARS-CoV-2-MA_virus|SARS-CoV-2_virus|SARS-CoV-MA_virus|SARS-CoV_virus SARS-CoV-2-MA_virus|SARS-CoV-MA_virus | C57BL/6NJinbred strain |
Hachim MY, Front Immunol 2020;11():1372 Schafer A, bioRxiv 2021 May;(): Schafer A, mBio 2022 Aug 30;13(4):e0145422 |
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C57BL/6N-Parp12tm1.1(KOMP)Vlcg/MbpMmucd | MGI:6346855 | coisogenic|mutant strain|targeted mutation | Kerr CM, J Virol 2023 Sep 28;97(9):e0088523 | J:340885 | Gene|Infection|Mouse_Hepatitis_virus | C57BL/6N-Parp12tm1.1(KOMP)Vlcg/MbpMmucdcoisogenic|mutant strain|targeted mutation |
Kerr CM, J Virol 2023 Sep 28;97(9):e0088523 |
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C57BL/6NTac | MGI:2164831 | inbred strain | Ngo VL, Cell Host Microbe 2024 Jan 23;(): | J:345954 | Infection|MERS-CoV-MA_virus | C57BL/6NTacinbred strain |
Ngo VL, Cell Host Microbe 2024 Jan 23;(): |
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C57BL/6-Tg(Aicda/EGFP)1Rcas/J | MGI:5318090 | coisogenic|mutant strain|transgenic | Luo Y, Signal Transduct Target Ther 2022 Jan 4;7(1):7 | J:333746 | SARS-CoV-2_virus|Vaccine | C57BL/6-Tg(Aicda/EGFP)1Rcas/Jcoisogenic|mutant strain|transgenic |
Luo Y, Signal Transduct Target Ther 2022 Jan 4;7(1):7 |
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C57BL/6-Tg(CAG-ACE2,-luc)1Smoc/Smoc | MGI:6476454 | coisogenic|mutant strain|transgenic | Yang S, J Med Virol 2022 Aug;94(8):3605-3612 | J:339218 | Pathology|SARS-CoV-2_virus|VOC_B.1.617.2_Delta | C57BL/6-Tg(CAG-ACE2,-luc)1Smoc/Smoccoisogenic|mutant strain|transgenic |
Yang S, J Med Virol 2022 Aug;94(8):3605-3612 |
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C57BL/6-Tg(CAG-DPP4)4Yuzh | MGI:6402444 | coisogenic|mutant strain|transgenic | MGI:6402445 | Tg(CAG-DPP4)4Yuzh | MGI:6402443 | Transgenic | Humanized sequence|Inserted expressed sequence | Middle East respiratory syndrome | DOID:0080642 | behavior/neurological cardiovascular system hematopoietic system homeostasis/metabolism immune system liver/biliary system nervous system renal/urinary system respiratory system mortality/aging | MP:0005386 MP:0005385 MP:0005397 MP:0005376 MP:0005387 MP:0005370 MP:0003631 MP:0005367 MP:0005388 MP:0010768 | Zhao G, PLoS One 2015;10(12):e0145561 | J:286175 | Infection|MERS-CoV_virus | C57BL/6-Tg(CAG-DPP4)4Yuzhcoisogenic|mutant strain|transgenic |
MGI:6402445 | behavior/neurological cardiovascular system hematopoietic system homeostasis/metabolism immune system liver/biliary system nervous system renal/urinary system respiratory system mortality/aging Middle East respiratory syndrome |
Zhao G, PLoS One 2015;10(12):e0145561 |
C57BL/6-Tg(CAG-EGFP)131Osb/LeySopJ | MGI:3706817 | coisogenic|mutant strain|transgenic | Hohsfield LA, Glia 2022 May;70(5):875-891 | J:324342 | Mouse_Hepatitis_virus | C57BL/6-Tg(CAG-EGFP)131Osb/LeySopJcoisogenic|mutant strain|transgenic |
Hohsfield LA, Glia 2022 May;70(5):875-891 |
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CAST/EiJ | MGI:2159793 | inbred strain|wild-derived | MGI:2659102 | cellular immune system nervous system mortality/aging | MP:0005384 MP:0005387 MP:0003631 MP:0010768 | Gralinski LE, PLoS Genet 2015 Oct;11(10):e1005504 Josset L, RNA Biol 2014;11(7):875-90 Peng X, mBio 2010 Oct 26;1(5): Peng X, mBio 2011;2(6): Xiong H, G3 (Bethesda) 2014 Jun 5;4(8):1429-44 | J:268979 J:276026 J:276986 J:276989 J:276183 | Infection|SARS-CoV-MA_virus SARS-CoV-MA_virus | CAST/EiJinbred strain|wild-derived |
MGI:2659102 | cellular immune system nervous system mortality/aging |
Gralinski LE, PLoS Genet 2015 Oct;11(10):e1005504 Josset L, RNA Biol 2014;11(7):875-90 Peng X, mBio 2010 Oct 26;1(5): Peng X, mBio 2011;2(6): Xiong H, G3 (Bethesda) 2014 Jun 5;4(8):1429-44 |
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(CAST/EiJ x B6.Cg-Tg(K18-ACE2)2Prlmn/J)F1/J | MGI:6865669 | F1 hybrid|mutant strain|transgenic | Robertson SJ, Nat Commun 2023 Jul 25;14(1):4481 | J:338561 | Infection|SARS-CoV-2_virus | (CAST/EiJ x B6.Cg-Tg(K18-ACE2)2Prlmn/J)F1/JF1 hybrid|mutant strain|transgenic |
Robertson SJ, Nat Commun 2023 Jul 25;14(1):4481 |
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C.B10-H2b/LilMcdJ | MGI:2161599 | congenic|major histocompatibility congenic|mutant strain | Khanolkar A, J Virol 2009 Sep;83(17):8946-56 | J:153918 | Mouse_Hepatitis_virus|Pathology | C.B10-H2b/LilMcdJcongenic|major histocompatibility congenic|mutant strain |
Khanolkar A, J Virol 2009 Sep;83(17):8946-56 |
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CBA/J | MGI:2159756 | inbred strain | Khanolkar A, J Virol 2009 Sep;83(17):8946-56 | J:153918 | Mouse_Hepatitis_virus|Pathology | CBA/Jinbred strain |
Khanolkar A, J Virol 2009 Sep;83(17):8946-56 |
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CC001/Unc | MGI:6202009 | recombinant inbred (RI) | Graham JB, iScience 2024 Mar 15;27(3):109103 | J:345413 | SARS-CoV-2-MA_virus | CC001/Uncrecombinant inbred (RI) |
Graham JB, iScience 2024 Mar 15;27(3):109103 |
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CC001/UncJ | MGI:5649079 | recombinant inbred (RI) | Graham JB, bioRxiv 2020 Sep 21;(): | J:296262 | SARS-CoV-MA_virus | CC001/UncJrecombinant inbred (RI) |
Graham JB, bioRxiv 2020 Sep 21;(): |
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(CC001/Unc x CC055/TauUnc)F1 | MGI:7596177 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC001/Unc x CC055/TauUnc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
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(CC001/Unc x CC074/Unc)F1 | MGI:7596178 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC001/Unc x CC074/Unc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
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CC002/Unc | MGI:6188584 | recombinant inbred (RI) | Graham JB, iScience 2024 Mar 15;27(3):109103 | J:345413 | SARS-CoV-2-MA_virus | CC002/Uncrecombinant inbred (RI) |
Graham JB, iScience 2024 Mar 15;27(3):109103 |
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(CC002/Unc x CC011/Unc)F1 | MGI:7596179 | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC002/Unc x CC011/Unc)F1 |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
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(CC002/Unc x CC021/Unc)F1 | MGI:7596180 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC002/Unc x CC021/Unc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
CC003/Unc | MGI:6188583 | recombinant inbred (RI) | Graham JB, iScience 2024 Mar 15;27(3):109103 Gralinski LE, G3 (Bethesda) 2017 Jun 7;7(6):1653-1663 | J:345413 J:270045 | SARS-CoV-2-MA_virus Pathology|SARS-CoV-MA_virus | CC003/Uncrecombinant inbred (RI) |
Graham JB, iScience 2024 Mar 15;27(3):109103 Gralinski LE, G3 (Bethesda) 2017 Jun 7;7(6):1653-1663 |
|||||||||||
(CC003/Unc x CC051/TauUnc)F1 | MGI:7596181 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC003/Unc x CC051/TauUnc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
(CC003/Unc x CC062/Unc)F1 | MGI:7596182 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC003/Unc x CC062/Unc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
CC004/TauUnc | MGI:6188582 | recombinant inbred (RI) | Graham JB, iScience 2024 Mar 15;27(3):109103 | J:345413 | SARS-CoV-2-MA_virus | CC004/TauUncrecombinant inbred (RI) |
Graham JB, iScience 2024 Mar 15;27(3):109103 |
|||||||||||
CC004/TauUncJ | MGI:5649082 | recombinant inbred (RI) | Graham JB, bioRxiv 2020 Sep 21;(): | J:296262 | SARS-CoV-MA_virus | CC004/TauUncJrecombinant inbred (RI) |
Graham JB, bioRxiv 2020 Sep 21;(): |
|||||||||||
(CC004/TauUnc x CC011/Unc)F1 | MGI:6307729 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC004/TauUnc x CC011/Unc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
(CC004/TauUnc x CC012/GeniUnc)F1 | MGI:7596183 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC004/TauUnc x CC012/GeniUnc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
CC005/TauUnc | MGI:6188581 | recombinant inbred (RI) | Graham JB, iScience 2024 Mar 15;27(3):109103 | J:345413 | SARS-CoV-2-MA_virus | CC005/TauUncrecombinant inbred (RI) |
Graham JB, iScience 2024 Mar 15;27(3):109103 |
|||||||||||
(CC005/TauUnc x CC001/Unc)F1 | MGI:6307730 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC005/TauUnc x CC001/Unc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
(CC005/TauUnc x CC038/GeniUnc)F1 | MGI:7596184 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC005/TauUnc x CC038/GeniUnc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
(CC005/TauUnc x CC040/TauUnc)F1 | MGI:6307737 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC005/TauUnc x CC040/TauUnc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
CC006/TauUnc | MGI:6188580 | recombinant inbred (RI) | Graham JB, iScience 2024 Mar 15;27(3):109103 | J:345413 | SARS-CoV-2-MA_virus | CC006/TauUncrecombinant inbred (RI) |
Graham JB, iScience 2024 Mar 15;27(3):109103 |
|||||||||||
CC006/TauUncJ | MGI:5649237 | recombinant inbred (RI) | Graham JB, bioRxiv 2020 Sep 21;(): | J:296262 | SARS-CoV-MA_virus | CC006/TauUncJrecombinant inbred (RI) |
Graham JB, bioRxiv 2020 Sep 21;(): |
|||||||||||
(CC006/TauUnc x CC007/Unc)F1 | MGI:7596185 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC006/TauUnc x CC007/Unc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
(CC006/TauUnc x CC039/Unc)F1 | MGI:7596186 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC006/TauUnc x CC039/Unc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
CC007/Unc | MGI:6188579 | recombinant inbred (RI) | Graham JB, iScience 2024 Mar 15;27(3):109103 | J:345413 | SARS-CoV-2-MA_virus | CC007/Uncrecombinant inbred (RI) |
Graham JB, iScience 2024 Mar 15;27(3):109103 |
|||||||||||
(CC007/Unc x CC070/TauUnc)F1 | MGI:7596187 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC007/Unc x CC070/TauUnc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
(CC007/Unc x CC075/Unc)F1 | MGI:7596188 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC007/Unc x CC075/Unc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
CC008/GeniUnc | MGI:6188578 | recombinant inbred (RI) | Graham JB, iScience 2024 Mar 15;27(3):109103 | J:345413 | SARS-CoV-2-MA_virus | CC008/GeniUncrecombinant inbred (RI) |
Graham JB, iScience 2024 Mar 15;27(3):109103 |
|||||||||||
(CC008/GeniUnc x CC009/Unc)F1 | MGI:7596189 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC008/GeniUnc x CC009/Unc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
(CC008/GeniUnc x CC010/GeniUnc)F1 | MGI:7596190 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC008/GeniUnc x CC010/GeniUnc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
(CC008/GeniUnc x CC018/Unc)F1 | MGI:7596191 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC008/GeniUnc x CC018/Unc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
CC009/Unc | MGI:6188577 | recombinant inbred (RI) | Graham JB, iScience 2024 Mar 15;27(3):109103 | J:345413 | SARS-CoV-2-MA_virus | CC009/Uncrecombinant inbred (RI) |
Graham JB, iScience 2024 Mar 15;27(3):109103 |
|||||||||||
(CC009/Unc x CC040/TauUnc)F1 | MGI:7596192 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC009/Unc x CC040/TauUnc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
CC010/GeniUnc | MGI:6188576 | recombinant inbred (RI) | Graham JB, iScience 2024 Mar 15;27(3):109103 | J:345413 | SARS-CoV-2-MA_virus | CC010/GeniUncrecombinant inbred (RI) |
Graham JB, iScience 2024 Mar 15;27(3):109103 |
|||||||||||
CC010/GeniUncJ | MGI:5649239 | recombinant inbred (RI) | Graham JB, bioRxiv 2020 Sep 21;(): | J:296262 | SARS-CoV-MA_virus | CC010/GeniUncJrecombinant inbred (RI) |
Graham JB, bioRxiv 2020 Sep 21;(): |
|||||||||||
(CC010/GeniUnc x CC015/Unc)F1 | MGI:7596193 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC010/GeniUnc x CC015/Unc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
(CC010/GeniUnc x CC060/Unc)F1 | MGI:7596194 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC010/GeniUnc x CC060/Unc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
CC011/Unc | MGI:5749398 | recombinant inbred (RI) | Graham JB, iScience 2024 Mar 15;27(3):109103 Schafer A, mBio 2022 Aug 30;13(4):e0145422 | J:345413 J:327836 | SARS-CoV-2-MA_virus SARS-CoV-2-MA_virus|SARS-CoV-MA_virus | CC011/Uncrecombinant inbred (RI) |
Graham JB, iScience 2024 Mar 15;27(3):109103 Schafer A, mBio 2022 Aug 30;13(4):e0145422 |
|||||||||||
CC011/UncJ | MGI:5649240 | recombinant inbred (RI) | Graham JB, bioRxiv 2020 Sep 21;(): | J:296262 | SARS-CoV-MA_virus | CC011/UncJrecombinant inbred (RI) |
Graham JB, bioRxiv 2020 Sep 21;(): |
|||||||||||
(CC011/Unc x CC032/GeniUnc)F1 | MGI:7596195 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC011/Unc x CC032/GeniUnc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
(CC011/Unc x CC042/GeniUnc)F1 | MGI:7596196 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC011/Unc x CC042/GeniUnc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
CC012/GeniUnc | MGI:6188575 | recombinant inbred (RI) | Graham JB, iScience 2024 Mar 15;27(3):109103 | J:345413 | SARS-CoV-2-MA_virus | CC012/GeniUncrecombinant inbred (RI) |
Graham JB, iScience 2024 Mar 15;27(3):109103 |
|||||||||||
CC012/GeniUncJ | MGI:5694080 | recombinant inbred (RI) | Graham JB, bioRxiv 2020 Sep 21;(): | J:296262 | SARS-CoV-MA_virus | CC012/GeniUncJrecombinant inbred (RI) |
Graham JB, bioRxiv 2020 Sep 21;(): |
|||||||||||
(CC012/GeniUnc x CC004/TauUnc)F1 | MGI:7596198 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC012/GeniUnc x CC004/TauUnc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
(CC012/GeniUnc x CC032/GeniUnc)F1 | MGI:7596200 | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC012/GeniUnc x CC032/GeniUnc)F1 |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
||||||||||||
(CC012/GeniUnc x CC038/GeniUnc)F1 | MGI:7596202 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC012/GeniUnc x CC038/GeniUnc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
CC013/GeniUnc | MGI:6188574 | recombinant inbred (RI) | Graham JB, iScience 2024 Mar 15;27(3):109103 | J:345413 | SARS-CoV-2-MA_virus | CC013/GeniUncrecombinant inbred (RI) |
Graham JB, iScience 2024 Mar 15;27(3):109103 |
|||||||||||
CC013/GeniUncJ | MGI:5649241 | recombinant inbred (RI) | Graham JB, bioRxiv 2020 Sep 21;(): | J:296262 | SARS-CoV-MA_virus | CC013/GeniUncJrecombinant inbred (RI) |
Graham JB, bioRxiv 2020 Sep 21;(): |
|||||||||||
(CC013/GeniUnc x CC026/GeniUnc)F1 | MGI:7596203 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC013/GeniUnc x CC026/GeniUnc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
(CC013/GeniUnc x CC041/TauUnc)F1 | MGI:7596204 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC013/GeniUnc x CC041/TauUnc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
CC014/UncJ | MGI:5659477 | recombinant inbred (RI) | Graham JB, bioRxiv 2020 Sep 21;(): | J:296262 | SARS-CoV-MA_virus | CC014/UncJrecombinant inbred (RI) |
Graham JB, bioRxiv 2020 Sep 21;(): |
|||||||||||
(CC014/Unc x CC059/TauUnc)F1 | MGI:7596205 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC014/Unc x CC059/TauUnc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
CC015/Unc | MGI:6188573 | recombinant inbred (RI) | Graham JB, iScience 2024 Mar 15;27(3):109103 | J:345413 | SARS-CoV-2-MA_virus | CC015/Uncrecombinant inbred (RI) |
Graham JB, iScience 2024 Mar 15;27(3):109103 |
|||||||||||
CC015/UncJ | MGI:5659478 | recombinant inbred (RI) | Graham JB, bioRxiv 2020 Sep 21;(): | J:296262 | SARS-CoV-MA_virus | CC015/UncJrecombinant inbred (RI) |
Graham JB, bioRxiv 2020 Sep 21;(): |
|||||||||||
(CC015/Unc x CC018/Unc)F1 | MGI:7596206 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC015/Unc x CC018/Unc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
(CC015/Unc x CC059/TauUnc)F1 | MGI:7596207 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC015/Unc x CC059/TauUnc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
CC016/GeniUnc | MGI:6188572 | recombinant inbred (RI) | Graham JB, iScience 2024 Mar 15;27(3):109103 | J:345413 | SARS-CoV-2-MA_virus | CC016/GeniUncrecombinant inbred (RI) |
Graham JB, iScience 2024 Mar 15;27(3):109103 |
|||||||||||
CC016/GeniUncJ | MGI:5659479 | recombinant inbred (RI) | Graham JB, bioRxiv 2020 Sep 21;(): | J:296262 | SARS-CoV-MA_virus | CC016/GeniUncJrecombinant inbred (RI) |
Graham JB, bioRxiv 2020 Sep 21;(): |
|||||||||||
(CC016/GeniUnc x CC038/GeniUnc)F1 | MGI:7596208 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC016/GeniUnc x CC038/GeniUnc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
(CC016/GeniUnc x CC061/GeniUnc)F1 | MGI:7596209 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC016/GeniUnc x CC061/GeniUnc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
CC017/Unc | MGI:6188571 | recombinant inbred (RI) | Graham JB, iScience 2024 Mar 15;27(3):109103 Schafer A, mBio 2022 Aug 30;13(4):e0145422 | J:345413 J:327836 | SARS-CoV-2-MA_virus SARS-CoV-2-MA_virus|SARS-CoV-MA_virus | CC017/Uncrecombinant inbred (RI) |
Graham JB, iScience 2024 Mar 15;27(3):109103 Schafer A, mBio 2022 Aug 30;13(4):e0145422 |
|||||||||||
(CC017/Unc x CC004/TauUnc)F1 | MGI:6307731 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC017/Unc x CC004/TauUnc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
(CC017/Unc x CC041/TauUnc)F1 | MGI:7596210 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC017/Unc x CC041/TauUnc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
CC018/Unc | MGI:6188570 | recombinant inbred (RI) | Graham JB, iScience 2024 Mar 15;27(3):109103 | J:345413 | SARS-CoV-2-MA_virus | CC018/Uncrecombinant inbred (RI) |
Graham JB, iScience 2024 Mar 15;27(3):109103 |
|||||||||||
CC018/UncJ | MGI:5649243 | recombinant inbred (RI) | Graham JB, bioRxiv 2020 Sep 21;(): | J:296262 | SARS-CoV-MA_virus | CC018/UncJrecombinant inbred (RI) |
Graham JB, bioRxiv 2020 Sep 21;(): |
|||||||||||
(CC018/Unc x CC009/Unc)F1 | MGI:7596211 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC018/Unc x CC009/Unc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
(CC018/Unc x CC065/Unc)F1 | MGI:7596212 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC018/Unc x CC065/Unc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
CC019/TauUnc | MGI:6188569 | recombinant inbred (RI) | Graham JB, iScience 2024 Mar 15;27(3):109103 | J:345413 | SARS-CoV-2-MA_virus | CC019/TauUncrecombinant inbred (RI) |
Graham JB, iScience 2024 Mar 15;27(3):109103 |
|||||||||||
CC019/TauUncJ | MGI:5649244 | recombinant inbred (RI) | Graham JB, bioRxiv 2020 Sep 21;(): | J:296262 | SARS-CoV-MA_virus | CC019/TauUncJrecombinant inbred (RI) |
Graham JB, bioRxiv 2020 Sep 21;(): |
|||||||||||
(CC019/TauUnc x CC002/Unc)F1 | MGI:7596213 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC019/TauUnc x CC002/Unc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
(CC019/TauUnc x CC004/TauUnc)F1 | MGI:7596214 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC019/TauUnc x CC004/TauUnc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
(CC019/TauUnc x CC027/GeniUnc)F1 | MGI:7596215 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC019/TauUnc x CC027/GeniUnc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
(CC020/GeniUnc x CC008/GeniUnc)F1 | MGI:7596216 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC020/GeniUnc x CC008/GeniUnc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
CC021/Unc | MGI:6188567 | recombinant inbred (RI) | Graham JB, iScience 2024 Mar 15;27(3):109103 | J:345413 | SARS-CoV-2-MA_virus | CC021/Uncrecombinant inbred (RI) |
Graham JB, iScience 2024 Mar 15;27(3):109103 |
|||||||||||
(CC021/Unc x CC023/GeniUnc)F1 | MGI:7596217 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC021/Unc x CC023/GeniUnc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
(CC022/GeniUnc x CC024/GeniUnc)F1 | MGI:7596218 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC022/GeniUnc x CC024/GeniUnc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
(CC022/GeniUnc x CC044/Unc)F1 | MGI:7596219 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC022/GeniUnc x CC044/Unc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
CC023/GeniUnc | MGI:6188565 | recombinant inbred (RI) | Graham JB, iScience 2024 Mar 15;27(3):109103 | J:345413 | SARS-CoV-2-MA_virus | CC023/GeniUncrecombinant inbred (RI) |
Graham JB, iScience 2024 Mar 15;27(3):109103 |
|||||||||||
CC023/GeniUncJ | MGI:5659483 | recombinant inbred (RI) | Graham JB, bioRxiv 2020 Sep 21;(): | J:296262 | SARS-CoV-MA_virus | CC023/GeniUncJrecombinant inbred (RI) |
Graham JB, bioRxiv 2020 Sep 21;(): |
|||||||||||
(CC023/GeniUnc x CC025/GeniUnc)F1 | MGI:7596220 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC023/GeniUnc x CC025/GeniUnc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
CC024/GeniUnc | MGI:6188564 | recombinant inbred (RI) | Graham JB, iScience 2024 Mar 15;27(3):109103 | J:345413 | SARS-CoV-2-MA_virus | CC024/GeniUncrecombinant inbred (RI) |
Graham JB, iScience 2024 Mar 15;27(3):109103 |
|||||||||||
CC024/GeniUncJ | MGI:5649245 | recombinant inbred (RI) | Graham JB, bioRxiv 2020 Sep 21;(): | J:296262 | SARS-CoV-MA_virus | CC024/GeniUncJrecombinant inbred (RI) |
Graham JB, bioRxiv 2020 Sep 21;(): |
|||||||||||
(CC024/GeniUnc x CC023/GeniUnc)F1 | MGI:6307732 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC024/GeniUnc x CC023/GeniUnc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
CC025/GeniUnc | MGI:6188563 | recombinant inbred (RI) | Graham JB, iScience 2024 Mar 15;27(3):109103 | J:345413 | SARS-CoV-2-MA_virus | CC025/GeniUncrecombinant inbred (RI) |
Graham JB, iScience 2024 Mar 15;27(3):109103 |
|||||||||||
CC025/GeniUncJ | MGI:5649246 | recombinant inbred (RI) | Graham JB, bioRxiv 2020 Sep 21;(): | J:296262 | SARS-CoV-MA_virus | CC025/GeniUncJrecombinant inbred (RI) |
Graham JB, bioRxiv 2020 Sep 21;(): |
|||||||||||
(CC025/GeniUnc x CC028/GeniUnc)F1 | MGI:7596222 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC025/GeniUnc x CC028/GeniUnc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
CC026/GeniUnc | MGI:6188562 | recombinant inbred (RI) | Graham JB, iScience 2024 Mar 15;27(3):109103 | J:345413 | SARS-CoV-2-MA_virus | CC026/GeniUncrecombinant inbred (RI) |
Graham JB, iScience 2024 Mar 15;27(3):109103 |
|||||||||||
CC026/GeniUncJ | MGI:5649247 | recombinant inbred (RI) | Graham JB, bioRxiv 2020 Sep 21;(): | J:296262 | SARS-CoV-MA_virus | CC026/GeniUncJrecombinant inbred (RI) |
Graham JB, bioRxiv 2020 Sep 21;(): |
|||||||||||
(CC026/GeniUnc x CC034/Unc)F1 | MGI:7596223 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC026/GeniUnc x CC034/Unc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
CC027/GeniUnc | MGI:6188561 | recombinant inbred (RI) | Graham JB, iScience 2024 Mar 15;27(3):109103 | J:345413 | SARS-CoV-2-MA_virus | CC027/GeniUncrecombinant inbred (RI) |
Graham JB, iScience 2024 Mar 15;27(3):109103 |
|||||||||||
(CC027/GeniUnc x CC036/Unc)F1 | MGI:7596224 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC027/GeniUnc x CC036/Unc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
(CC027/GeniUnc x CC045/GeniUnc)F1 | MGI:7596225 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC027/GeniUnc x CC045/GeniUnc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
CC028/GeniUnc | MGI:6188560 | recombinant inbred (RI) | Graham JB, iScience 2024 Mar 15;27(3):109103 | J:345413 | SARS-CoV-2-MA_virus | CC028/GeniUncrecombinant inbred (RI) |
Graham JB, iScience 2024 Mar 15;27(3):109103 |
|||||||||||
CC028/GeniUncJ | MGI:5659485 | recombinant inbred (RI) | Graham JB, bioRxiv 2020 Sep 21;(): | J:296262 | SARS-CoV-MA_virus | CC028/GeniUncJrecombinant inbred (RI) |
Graham JB, bioRxiv 2020 Sep 21;(): |
|||||||||||
(CC028/GeniUnc x CC024/GeniUnc)F1 | MGI:7596226 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC028/GeniUnc x CC024/GeniUnc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
(CC028/GeniUnc x CC030/GeniUnc)F1 | MGI:7596227 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC028/GeniUnc x CC030/GeniUnc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
CC029/Unc | MGI:6188559 | recombinant inbred (RI) | Graham JB, iScience 2024 Mar 15;27(3):109103 | J:345413 | SARS-CoV-2-MA_virus | CC029/Uncrecombinant inbred (RI) |
Graham JB, iScience 2024 Mar 15;27(3):109103 |
|||||||||||
CC029/UncJ | MGI:5659486 | recombinant inbred (RI) | Graham JB, bioRxiv 2020 Sep 21;(): | J:296262 | SARS-CoV-MA_virus | CC029/UncJrecombinant inbred (RI) |
Graham JB, bioRxiv 2020 Sep 21;(): |
|||||||||||
(CC029/Unc x CC027/GeniUnc)F1 | MGI:7596228 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC029/Unc x CC027/GeniUnc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
(CC029/Unc x CC071/TauUnc)F1 | MGI:7596229 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC029/Unc x CC071/TauUnc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
CC030/GeniUnc | MGI:6188558 | recombinant inbred (RI) | Graham JB, iScience 2024 Mar 15;27(3):109103 | J:345413 | SARS-CoV-2-MA_virus | CC030/GeniUncrecombinant inbred (RI) |
Graham JB, iScience 2024 Mar 15;27(3):109103 |
|||||||||||
CC030/GeniUncJ | MGI:5659487 | recombinant inbred (RI) | Graham JB, bioRxiv 2020 Sep 21;(): | J:296262 | SARS-CoV-MA_virus | CC030/GeniUncJrecombinant inbred (RI) |
Graham JB, bioRxiv 2020 Sep 21;(): |
|||||||||||
(CC030/GeniUnc x CC023/GeniUnc)F1 | MGI:7596230 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC030/GeniUnc x CC023/GeniUnc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
(CC030/GeniUnc x CC042/GeniUnc)F1 | MGI:7596231 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC030/GeniUnc x CC042/GeniUnc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
(CC030/GeniUnc x CC061/GeniUnc)F1 | MGI:7596232 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC030/GeniUnc x CC061/GeniUnc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
CC031/GeniUnc | MGI:6188557 | recombinant inbred (RI) | Graham JB, iScience 2024 Mar 15;27(3):109103 | J:345413 | SARS-CoV-2-MA_virus | CC031/GeniUncrecombinant inbred (RI) |
Graham JB, iScience 2024 Mar 15;27(3):109103 |
|||||||||||
CC032/GeniUnc | MGI:6188556 | recombinant inbred (RI) | Graham JB, iScience 2024 Mar 15;27(3):109103 | J:345413 | SARS-CoV-2-MA_virus | CC032/GeniUncrecombinant inbred (RI) |
Graham JB, iScience 2024 Mar 15;27(3):109103 |
|||||||||||
CC032/GeniUncJ | MGI:5649248 | recombinant inbred (RI) | Graham JB, bioRxiv 2020 Sep 21;(): | J:296262 | SARS-CoV-MA_virus | CC032/GeniUncJrecombinant inbred (RI) |
Graham JB, bioRxiv 2020 Sep 21;(): |
|||||||||||
(CC032/GeniUnc x CC013/GeniUnc)F1 | MGI:7596233 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC032/GeniUnc x CC013/GeniUnc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
(CC032/GeniUnc x CC017/Unc)F1 | MGI:7596234 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC032/GeniUnc x CC017/Unc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
CC033/GeniUnc | MGI:6188555 | recombinant inbred (RI) | Graham JB, iScience 2024 Mar 15;27(3):109103 | J:345413 | SARS-CoV-2-MA_virus | CC033/GeniUncrecombinant inbred (RI) |
Graham JB, iScience 2024 Mar 15;27(3):109103 |
|||||||||||
CC033/GeniUncJ | MGI:5659488 | recombinant inbred (RI) | Graham JB, bioRxiv 2020 Sep 21;(): | J:296262 | SARS-CoV-MA_virus | CC033/GeniUncJrecombinant inbred (RI) |
Graham JB, bioRxiv 2020 Sep 21;(): |
|||||||||||
(CC033/GeniUnc x CC046/Unc)F1 | MGI:7596235 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC033/GeniUnc x CC046/Unc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
(CC033/GeniUnc x CC068/TauUnc)F1 | MGI:7596236 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC033/GeniUnc x CC068/TauUnc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
CC034/Unc | MGI:6188554 | recombinant inbred (RI) | Graham JB, bioRxiv 2020 Sep 21;(): | J:296262 | SARS-CoV-MA_virus | CC034/Uncrecombinant inbred (RI) |
Graham JB, bioRxiv 2020 Sep 21;(): |
|||||||||||
(CC034/Unc x CC016/GeniUnc)F1 | MGI:7596237 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC034/Unc x CC016/GeniUnc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
CC035/Unc | MGI:6188553 | recombinant inbred (RI) | Graham JB, iScience 2024 Mar 15;27(3):109103 | J:345413 | SARS-CoV-2-MA_virus | CC035/Uncrecombinant inbred (RI) |
Graham JB, iScience 2024 Mar 15;27(3):109103 |
|||||||||||
(CC035/Unc x CC020/GeniUnc)F1 | MGI:7596238 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC035/Unc x CC020/GeniUnc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
(CC035/Unc x CC071/TauUnc)F1 | MGI:7596239 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC035/Unc x CC071/TauUnc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
CC036/Unc | MGI:6188552 | recombinant inbred (RI) | Graham JB, iScience 2024 Mar 15;27(3):109103 | J:345413 | SARS-CoV-2-MA_virus | CC036/Uncrecombinant inbred (RI) |
Graham JB, iScience 2024 Mar 15;27(3):109103 |
|||||||||||
(CC036/Unc x CC051/TauUnc)F1 | MGI:7596240 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC036/Unc x CC051/TauUnc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
CC037/TauUnc | MGI:6188551 | recombinant inbred (RI) | Graham JB, iScience 2024 Mar 15;27(3):109103 | J:345413 | SARS-CoV-2-MA_virus | CC037/TauUncrecombinant inbred (RI) |
Graham JB, iScience 2024 Mar 15;27(3):109103 |
|||||||||||
CC037/TauUncJ | MGI:5649249 | recombinant inbred (RI) | Graham JB, bioRxiv 2020 Sep 21;(): | J:296262 | SARS-CoV-MA_virus | CC037/TauUncJrecombinant inbred (RI) |
Graham JB, bioRxiv 2020 Sep 21;(): |
|||||||||||
(CC037/TauUnc x CC046/Unc)F1 | MGI:7596242 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC037/TauUnc x CC046/Unc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
(CC037/TauUnc x CC057/Unc)F1 | MGI:7596243 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC037/TauUnc x CC057/Unc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
CC038/GeniUnc | MGI:6188550 | recombinant inbred (RI) | Graham JB, iScience 2024 Mar 15;27(3):109103 | J:345413 | SARS-CoV-2-MA_virus | CC038/GeniUncrecombinant inbred (RI) |
Graham JB, iScience 2024 Mar 15;27(3):109103 |
|||||||||||
CC038/GeniUncJ | MGI:5659491 | recombinant inbred (RI) | Graham JB, bioRxiv 2020 Sep 21;(): | J:296262 | SARS-CoV-MA_virus | CC038/GeniUncJrecombinant inbred (RI) |
Graham JB, bioRxiv 2020 Sep 21;(): |
|||||||||||
(CC038/GeniUnc x CC013/GeniUnc)F1 | MGI:7596244 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC038/GeniUnc x CC013/GeniUnc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
CC039/Unc | MGI:6188549 | recombinant inbred (RI) | Graham JB, iScience 2024 Mar 15;27(3):109103 | J:345413 | SARS-CoV-2-MA_virus | CC039/Uncrecombinant inbred (RI) |
Graham JB, iScience 2024 Mar 15;27(3):109103 |
|||||||||||
CC039/UncJ | MGI:5659492 | recombinant inbred (RI) | Graham JB, bioRxiv 2020 Sep 21;(): | J:296262 | SARS-CoV-MA_virus | CC039/UncJrecombinant inbred (RI) |
Graham JB, bioRxiv 2020 Sep 21;(): |
|||||||||||
CC040/TauUnc | MGI:6188548 | recombinant inbred (RI) | Graham JB, iScience 2024 Mar 15;27(3):109103 | J:345413 | SARS-CoV-2-MA_virus | CC040/TauUncrecombinant inbred (RI) |
Graham JB, iScience 2024 Mar 15;27(3):109103 |
|||||||||||
(CC040/TauUnc x CC003/Unc)F1 | MGI:7596247 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC040/TauUnc x CC003/Unc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
(CC040/TauUnc x CC015/Unc)F1 | MGI:7596248 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC040/TauUnc x CC015/Unc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
CC041/TauUnc | MGI:6188547 | recombinant inbred (RI) | Graham JB, iScience 2024 Mar 15;27(3):109103 | J:345413 | SARS-CoV-2-MA_virus | CC041/TauUncrecombinant inbred (RI) |
Graham JB, iScience 2024 Mar 15;27(3):109103 |
|||||||||||
CC041/TauUncJ | MGI:5649251 | recombinant inbred (RI) | Graham JB, bioRxiv 2020 Sep 21;(): | J:296262 | SARS-CoV-MA_virus | CC041/TauUncJrecombinant inbred (RI) |
Graham JB, bioRxiv 2020 Sep 21;(): |
|||||||||||
(CC041/TauUnc x CC012/GeniUnc)F1 | MGI:6307733 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC041/TauUnc x CC012/GeniUnc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
(CC041/TauUnc x CC016/GeniUnc)F1 | MGI:7596249 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC041/TauUnc x CC016/GeniUnc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
CC042/GeniUnc | MGI:6188546 | recombinant inbred (RI) | Graham JB, iScience 2024 Mar 15;27(3):109103 | J:345413 | SARS-CoV-2-MA_virus | CC042/GeniUncrecombinant inbred (RI) |
Graham JB, iScience 2024 Mar 15;27(3):109103 |
|||||||||||
CC042/GeniUncJ | MGI:5649255 | recombinant inbred (RI) | Graham JB, bioRxiv 2020 Sep 21;(): | J:296262 | SARS-CoV-MA_virus | CC042/GeniUncJrecombinant inbred (RI) |
Graham JB, bioRxiv 2020 Sep 21;(): |
|||||||||||
(CC042/GeniUnc x CC017/Unc)F1 | MGI:7596250 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC042/GeniUnc x CC017/Unc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
(CC042/GeniUnc x CC019/TauUnc)F1 | MGI:7596251 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC042/GeniUnc x CC019/TauUnc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
(CC042/GeniUnc x CC025/GeniUnc)F1 | MGI:7596316 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC042/GeniUnc x CC025/GeniUnc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
CC043/GeniUnc | MGI:6188545 | recombinant inbred (RI) | Graham JB, iScience 2024 Mar 15;27(3):109103 | J:345413 | SARS-CoV-2-MA_virus | CC043/GeniUncrecombinant inbred (RI) |
Graham JB, iScience 2024 Mar 15;27(3):109103 |
|||||||||||
CC043/GeniUncJ | MGI:5649256 | recombinant inbred (RI) | Graham JB, bioRxiv 2020 Sep 21;(): | J:296262 | SARS-CoV-MA_virus | CC043/GeniUncJrecombinant inbred (RI) |
Graham JB, bioRxiv 2020 Sep 21;(): |
|||||||||||
(CC043/GeniUnc x CC033/GeniUnc)F1 | MGI:7596254 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC043/GeniUnc x CC033/GeniUnc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
(CC043/GeniUnc x CC037/TauUnc)F1 | MGI:7596257 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC043/GeniUnc x CC037/TauUnc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
CC044/Unc | MGI:6188544 | recombinant inbred (RI) | Graham JB, iScience 2024 Mar 15;27(3):109103 | J:345413 | SARS-CoV-2-MA_virus | CC044/Uncrecombinant inbred (RI) |
Graham JB, iScience 2024 Mar 15;27(3):109103 |
|||||||||||
(CC044/Unc x CC060/Unc)F1 | MGI:7596258 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC044/Unc x CC060/Unc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
CC045/GeniUnc | MGI:6188543 | recombinant inbred (RI) | Graham JB, iScience 2024 Mar 15;27(3):109103 | J:345413 | SARS-CoV-2-MA_virus | CC045/GeniUncrecombinant inbred (RI) |
Graham JB, iScience 2024 Mar 15;27(3):109103 |
|||||||||||
(CC045/GeniUnc x CC044/Unc)F1 | MGI:7596260 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC045/GeniUnc x CC044/Unc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
CC046/Unc | MGI:6188542 | recombinant inbred (RI) | Graham JB, iScience 2024 Mar 15;27(3):109103 | J:345413 | SARS-CoV-2-MA_virus | CC046/Uncrecombinant inbred (RI) |
Graham JB, iScience 2024 Mar 15;27(3):109103 |
|||||||||||
CC046/UncJ | MGI:5659495 | recombinant inbred (RI) | Graham JB, bioRxiv 2020 Sep 21;(): | J:296262 | SARS-CoV-MA_virus | CC046/UncJrecombinant inbred (RI) |
Graham JB, bioRxiv 2020 Sep 21;(): |
|||||||||||
(CC046/Unc x CC068/TauUnc)F1 | MGI:7596262 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC046/Unc x CC068/TauUnc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
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CC049/TauUnc | MGI:6188540 | recombinant inbred (RI) | Graham JB, iScience 2024 Mar 15;27(3):109103 | J:345413 | SARS-CoV-2-MA_virus | CC049/TauUncrecombinant inbred (RI) |
Graham JB, iScience 2024 Mar 15;27(3):109103 |
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(CC049/TauUnc x CC036/Unc)F1 | MGI:7596264 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC049/TauUnc x CC036/Unc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
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CC051/TauUnc | MGI:6188538 | recombinant inbred (RI) | Graham JB, iScience 2024 Mar 15;27(3):109103 | J:345413 | SARS-CoV-2-MA_virus | CC051/TauUncrecombinant inbred (RI) |
Graham JB, iScience 2024 Mar 15;27(3):109103 |
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(CC051/TauUnc x CC005/TauUnc)F1 | MGI:7596265 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC051/TauUnc x CC005/TauUnc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
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(CC051/TauUnc x CC009/Unc)F1 | MGI:7596267 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC051/TauUnc x CC009/Unc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
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CC052/GeniUncJ | MGI:5659498 | recombinant inbred (RI) | Graham JB, bioRxiv 2020 Sep 21;(): | J:296262 | SARS-CoV-MA_virus | CC052/GeniUncJrecombinant inbred (RI) |
Graham JB, bioRxiv 2020 Sep 21;(): |
|||||||||||
(CC052/GeniUnc x CC007/Unc)F1 | MGI:7596268 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC052/GeniUnc x CC007/Unc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
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(CC052/GeniUnc x CC014/Unc)F1 | MGI:7596269 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC052/GeniUnc x CC014/Unc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
CC053/Unc | MGI:6188536 | recombinant inbred (RI) | MGI:6402903 | severe acute respiratory syndrome | DOID:2945 | immune system mortality/aging | MP:0005387 MP:0010768 | Graham JB, iScience 2024 Mar 15;27(3):109103 Gralinski LE, G3 (Bethesda) 2017 Jun 7;7(6):1653-1663 | J:345413 J:270045 | SARS-CoV-2-MA_virus Pathology|SARS-CoV-MA_virus | CC053/Uncrecombinant inbred (RI) |
MGI:6402903 | immune system mortality/aging severe acute respiratory syndrome |
Graham JB, iScience 2024 Mar 15;27(3):109103 Gralinski LE, G3 (Bethesda) 2017 Jun 7;7(6):1653-1663 |
||||
CC055/TauUncJ | MGI:5659644 | recombinant inbred (RI) | Graham JB, bioRxiv 2020 Sep 21;(): | J:296262 | SARS-CoV-MA_virus | CC055/TauUncJrecombinant inbred (RI) |
Graham JB, bioRxiv 2020 Sep 21;(): |
|||||||||||
(CC055/TauUnc x CC006/TauUnc)F1 | MGI:7596270 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC055/TauUnc x CC006/TauUnc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
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(CC055/TauUnc x CC028/GeniUnc)F1 | MGI:7596271 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC055/TauUnc x CC028/GeniUnc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
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CC056/GeniUncJ | MGI:5816616 | mutant strain|recombinant inbred (RI) | Graham JB, bioRxiv 2020 Sep 21;(): | J:296262 | SARS-CoV-MA_virus | CC056/GeniUncJmutant strain|recombinant inbred (RI) |
Graham JB, bioRxiv 2020 Sep 21;(): |
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(CC056/GeniUnc x CC033/GeniUnc)F1 | MGI:7596272 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC056/GeniUnc x CC033/GeniUnc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
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CC057/Unc | MGI:6188533 | recombinant inbred (RI) | Graham JB, iScience 2024 Mar 15;27(3):109103 | J:345413 | SARS-CoV-2-MA_virus | CC057/Uncrecombinant inbred (RI) |
Graham JB, iScience 2024 Mar 15;27(3):109103 |
|||||||||||
CC057/UncJ | MGI:5659646 | recombinant inbred (RI) | Graham JB, bioRxiv 2020 Sep 21;(): | J:296262 | SARS-CoV-MA_virus | CC057/UncJrecombinant inbred (RI) |
Graham JB, bioRxiv 2020 Sep 21;(): |
|||||||||||
(CC057/Unc x CC052/GeniUnc)F1 | MGI:7596273 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC057/Unc x CC052/GeniUnc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
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CC058/Unc | MGI:6188532 | recombinant inbred (RI) | Graham JB, iScience 2024 Mar 15;27(3):109103 | J:345413 | SARS-CoV-2-MA_virus | CC058/Uncrecombinant inbred (RI) |
Graham JB, iScience 2024 Mar 15;27(3):109103 |
|||||||||||
CC058/UncJ | MGI:5659649 | recombinant inbred (RI) | Graham JB, bioRxiv 2020 Sep 21;(): | J:296262 | SARS-CoV-MA_virus | CC058/UncJrecombinant inbred (RI) |
Graham JB, bioRxiv 2020 Sep 21;(): |
|||||||||||
(CC058/Unc x CC022/GeniUnc)F1 | MGI:7596274 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC058/Unc x CC022/GeniUnc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
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CC059/TauUnc | MGI:6188531 | recombinant inbred (RI) | Graham JB, iScience 2024 Mar 15;27(3):109103 | J:345413 | SARS-CoV-2-MA_virus | CC059/TauUncrecombinant inbred (RI) |
Graham JB, iScience 2024 Mar 15;27(3):109103 |
|||||||||||
CC059/TauUncJ | MGI:5659650 | recombinant inbred (RI) | Graham JB, bioRxiv 2020 Sep 21;(): | J:296262 | SARS-CoV-MA_virus | CC059/TauUncJrecombinant inbred (RI) |
Graham JB, bioRxiv 2020 Sep 21;(): |
|||||||||||
(CC059/TauUnc x CC065/Unc)F1 | MGI:7596275 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC059/TauUnc x CC065/Unc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
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CC060/Unc | MGI:6188530 | recombinant inbred (RI) | Graham JB, iScience 2024 Mar 15;27(3):109103 | J:345413 | SARS-CoV-2-MA_virus | CC060/Uncrecombinant inbred (RI) |
Graham JB, iScience 2024 Mar 15;27(3):109103 |
|||||||||||
CC060/UncJ | MGI:5659652 | recombinant inbred (RI) | Graham JB, bioRxiv 2020 Sep 21;(): | J:296262 | SARS-CoV-MA_virus | CC060/UncJrecombinant inbred (RI) |
Graham JB, bioRxiv 2020 Sep 21;(): |
|||||||||||
(CC060/Unc x CC006/TauUnc)F1 | MGI:7596276 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC060/Unc x CC006/TauUnc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
(CC060/Unc x CC037/TauUnc)F1 | MGI:7596277 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC060/Unc x CC037/TauUnc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
CC061/GeniUnc | MGI:6188529 | recombinant inbred (RI) | Graham JB, iScience 2024 Mar 15;27(3):109103 | J:345413 | SARS-CoV-2-MA_virus | CC061/GeniUncrecombinant inbred (RI) |
Graham JB, iScience 2024 Mar 15;27(3):109103 |
|||||||||||
CC061/GeniUncJ | MGI:5649258 | recombinant inbred (RI) | Graham JB, bioRxiv 2020 Sep 21;(): | J:296262 | SARS-CoV-MA_virus | CC061/GeniUncJrecombinant inbred (RI) |
Graham JB, bioRxiv 2020 Sep 21;(): |
|||||||||||
(CC061/GeniUnc x CC025/GeniUnc)F1 | MGI:7596278 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC061/GeniUnc x CC025/GeniUnc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
(CC061/GeniUnc x CC026/GeniUnc)F1 | MGI:7596279 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC061/GeniUnc x CC026/GeniUnc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
(CC061/GeniUnc x CC039/Unc)F1 | MGI:7596280 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC061/GeniUnc x CC039/Unc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
CC062/Unc | MGI:6188528 | recombinant inbred (RI) | Graham JB, iScience 2024 Mar 15;27(3):109103 | J:345413 | SARS-CoV-2-MA_virus | CC062/Uncrecombinant inbred (RI) |
Graham JB, iScience 2024 Mar 15;27(3):109103 |
|||||||||||
CC062/UncJ | MGI:5906018 | recombinant inbred (RI) | Graham JB, bioRxiv 2020 Sep 21;(): | J:296262 | SARS-CoV-MA_virus | CC062/UncJrecombinant inbred (RI) |
Graham JB, bioRxiv 2020 Sep 21;(): |
|||||||||||
(CC062/Unc x CC046/Unc)F1 | MGI:7596281 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC062/Unc x CC046/Unc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
(CC062/Unc x CC072/TauUnc)F1 | MGI:7596282 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC062/Unc x CC072/TauUnc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
(CC063/Unc x CC001/Unc)F1 | MGI:7596283 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC063/Unc x CC001/Unc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
(CC063/Unc x CC002/Unc)F1 | MGI:7596284 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC063/Unc x CC002/Unc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
CC065/Unc | MGI:6188526 | recombinant inbred (RI) | Graham JB, iScience 2024 Mar 15;27(3):109103 | J:345413 | SARS-CoV-2-MA_virus | CC065/Uncrecombinant inbred (RI) |
Graham JB, iScience 2024 Mar 15;27(3):109103 |
|||||||||||
CC065/UncJ | MGI:5659659 | recombinant inbred (RI) | Graham JB, bioRxiv 2020 Sep 21;(): | J:296262 | SARS-CoV-MA_virus | CC065/UncJrecombinant inbred (RI) |
Graham JB, bioRxiv 2020 Sep 21;(): |
|||||||||||
(CC065/Unc x CC010/GeniUnc)F1 | MGI:7596285 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC065/Unc x CC010/GeniUnc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
(CC065/Unc x CC018/Unc)F1 | MGI:7596286 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC065/Unc x CC018/Unc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
(CC065/Unc x CC072/TauUnc)F1 | MGI:7596287 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC065/Unc x CC072/TauUnc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
CC068/TauUnc | MGI:6188525 | recombinant inbred (RI) | Graham JB, iScience 2024 Mar 15;27(3):109103 | J:345413 | SARS-CoV-2-MA_virus | CC068/TauUncrecombinant inbred (RI) |
Graham JB, iScience 2024 Mar 15;27(3):109103 |
|||||||||||
CC068/TauUncJ | MGI:5649259 | recombinant inbred (RI) | Graham JB, bioRxiv 2020 Sep 21;(): | J:296262 | SARS-CoV-MA_virus | CC068/TauUncJrecombinant inbred (RI) |
Graham JB, bioRxiv 2020 Sep 21;(): |
|||||||||||
(CC068/TauUnc x CC035/Unc)F1 | MGI:7596288 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC068/TauUnc x CC035/Unc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
(CC068/TauUnc x CC043/GeniUnc)F1 | MGI:7596289 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC068/TauUnc x CC043/GeniUnc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
(CC070/TauUnc x CC003/Unc)F1 | MGI:7596290 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC070/TauUnc x CC003/Unc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
CC071/TauUnc | MGI:6188523 | recombinant inbred (RI) | Graham JB, iScience 2024 Mar 15;27(3):109103 | J:345413 | SARS-CoV-2-MA_virus | CC071/TauUncrecombinant inbred (RI) |
Graham JB, iScience 2024 Mar 15;27(3):109103 |
|||||||||||
CC071/TauUncJ | MGI:5659663 | recombinant inbred (RI) | Graham JB, bioRxiv 2020 Sep 21;(): | J:296262 | SARS-CoV-MA_virus | CC071/TauUncJrecombinant inbred (RI) |
Graham JB, bioRxiv 2020 Sep 21;(): |
|||||||||||
(CC071/TauUnc x CC053/Unc)F1 | MGI:7596291 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC071/TauUnc x CC053/Unc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
(CC071/TauUnc x CC058/Unc)F1 | MGI:7596292 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC071/TauUnc x CC058/Unc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
CC072/TauUnc | MGI:6188522 | recombinant inbred (RI) | Graham JB, iScience 2024 Mar 15;27(3):109103 | J:345413 | SARS-CoV-2-MA_virus | CC072/TauUncrecombinant inbred (RI) |
Graham JB, iScience 2024 Mar 15;27(3):109103 |
|||||||||||
(CC072/TauUnc x CC063/Unc)F1 | MGI:7596293 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC072/TauUnc x CC063/Unc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
(CC072/TauUnc x CC075/Unc)F1 | MGI:7596294 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC072/TauUnc x CC075/Unc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
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CC074/Unc | MGI:6188520 | recombinant inbred (RI) | Graham JB, iScience 2024 Mar 15;27(3):109103 | J:345413 | SARS-CoV-2-MA_virus | CC074/Uncrecombinant inbred (RI) |
Graham JB, iScience 2024 Mar 15;27(3):109103 |
|||||||||||
CC074/UncJ | MGI:5659666 | recombinant inbred (RI) | Graham JB, bioRxiv 2020 Sep 21;(): | J:296262 | SARS-CoV-MA_virus | CC074/UncJrecombinant inbred (RI) |
Graham JB, bioRxiv 2020 Sep 21;(): |
|||||||||||
(CC074/Unc x CC002/Unc)F1 | MGI:7596295 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC074/Unc x CC002/Unc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
(CC074/Unc x CC058/Unc)F1 | MGI:7596296 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC074/Unc x CC058/Unc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
(CC074/Unc x CC062/Unc)F1 | MGI:7596297 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC074/Unc x CC062/Unc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
CC075/Unc | MGI:6188519 | recombinant inbred (RI) | Graham JB, iScience 2024 Mar 15;27(3):109103 | J:345413 | SARS-CoV-2-MA_virus | CC075/Uncrecombinant inbred (RI) |
Graham JB, iScience 2024 Mar 15;27(3):109103 |
|||||||||||
(CC075/Unc x CC021/Unc)F1 | MGI:7596298 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC075/Unc x CC021/Unc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
(CC075/Unc x CC035/Unc)F1 | MGI:7596299 | F1 hybrid | Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 | J:303526 | Infection|SARS-CoV-2-MA_virus | (CC075/Unc x CC035/Unc)F1F1 hybrid |
Graham JB, PLoS Pathog 2021 Jan;17(1):e1009287 |
|||||||||||
CC078/TauUnc | MGI:6188517 | recombinant inbred (RI) | Graham JB, iScience 2024 Mar 15;27(3):109103 | J:345413 | SARS-CoV-2-MA_virus | CC078/TauUncrecombinant inbred (RI) |
Graham JB, iScience 2024 Mar 15;27(3):109103 |
|||||||||||
CC079/TauUnc | MGI:6188516 | recombinant inbred (RI) | Graham JB, iScience 2024 Mar 15;27(3):109103 | J:345413 | SARS-CoV-2-MA_virus | CC079/TauUncrecombinant inbred (RI) |
Graham JB, iScience 2024 Mar 15;27(3):109103 |
|||||||||||
CC080/TauUnc | MGI:6188515 | recombinant inbred (RI) | Graham JB, iScience 2024 Mar 15;27(3):109103 | J:345413 | SARS-CoV-2-MA_virus | CC080/TauUncrecombinant inbred (RI) |
Graham JB, iScience 2024 Mar 15;27(3):109103 |
|||||||||||
CC081/Unc | MGI:6188514 | recombinant inbred (RI) | Graham JB, iScience 2024 Mar 15;27(3):109103 | J:345413 | SARS-CoV-2-MA_virus | CC081/Uncrecombinant inbred (RI) |
Graham JB, iScience 2024 Mar 15;27(3):109103 |
|||||||||||
CC083/Unc | MGI:6188512 | recombinant inbred (RI) | Graham JB, iScience 2024 Mar 15;27(3):109103 | J:345413 | SARS-CoV-2-MA_virus | CC083/Uncrecombinant inbred (RI) |
Graham JB, iScience 2024 Mar 15;27(3):109103 |
|||||||||||
CC084/TauUnc | MGI:7596534 | recombinant inbred (RI) | Graham JB, iScience 2024 Mar 15;27(3):109103 | J:345413 | SARS-CoV-2-MA_virus | CC084/TauUncrecombinant inbred (RI) |
Graham JB, iScience 2024 Mar 15;27(3):109103 |
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C.C3-H2k/LilMcdJ | MGI:2163605 | congenic|major histocompatibility congenic|mutant strain | Khanolkar A, J Virol 2009 Sep;83(17):8946-56 | J:153918 | Mouse_Hepatitis_virus|Pathology | C.C3-H2k/LilMcdJcongenic|major histocompatibility congenic|mutant strain |
Khanolkar A, J Virol 2009 Sep;83(17):8946-56 |
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C.Cg-Cd19tm1(cre)Cgn Ighb/J | MGI:2174231 | congenic|mutant strain|targeted mutation | Kotagiri P, EBioMedicine 2022 Feb 18;77():103878 | J:322643 | SARS-CoV-2_virus | C.Cg-Cd19tm1(cre)Cgn Ighb/Jcongenic|mutant strain|targeted mutation |
Kotagiri P, EBioMedicine 2022 Feb 18;77():103878 |
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C.Cg-Tg(K18-ACE2)2Prlmn/J | MGI:6479852 | congenic|mutant strain|transgenic | McCray PB Jr, J Virol 2007 Jan;81(2):813-21 | J:283648 | Infection|SARS-CoV_virus | C.Cg-Tg(K18-ACE2)2Prlmn/Jcongenic|mutant strain|transgenic |
McCray PB Jr, J Virol 2007 Jan;81(2):813-21 |
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CD-1 | MGI:5649524 | outbred stock | Borriello F, bioRxiv 2021 Sep;(): Chadchan SB, Biol Reprod 2021 Feb 11;104(2):336-343 Dai W, Science 2020 Jun 19;368(6497):1331-1335 Duty JA, Med 2022 Oct 14;3(10):705-721.e11 Falach R, bioRxiv 2020 Nov;(): Fernandez-Castaneda A, bioRxiv 2022;(): Grandi A, bioRxiv 2021 Jul;(): Hassler L, bioRxiv 2021 Mar;(): King RG, bioRxiv 2020;(): Rice A, bioRxiv 2021 Mar;(): Rice A, bioRxiv 2021 Nov;(): Rice A, Sci Rep 2021 Jul 21;11(1):14917 Spencer AJ, bioRxiv 2021 Jan;(): Tummino TA, bioRxiv 2021 Mar;(): | J:310116 J:302245 J:290792 J:349963 J:296678 J:321759 J:308639 J:302921 J:296068 J:303210 J:315738 J:308902 J:302146 J:303456 | SARS-CoV-2_virus|Vaccine Gene SARS-CoV_virus|Treatment SARS-CoV-2_virus|Treatment|VOC_B.1.1.529_Omicron Comorbidity|Infection|SARS-CoV-2_virus Pathology|SARS-CoV-2_virus SARS-CoV-2_virus|Treatment | CD-1outbred stock |
Borriello F, bioRxiv 2021 Sep;(): Chadchan SB, Biol Reprod 2021 Feb 11;104(2):336-343 Dai W, Science 2020 Jun 19;368(6497):1331-1335 Duty JA, Med 2022 Oct 14;3(10):705-721.e11 Falach R, bioRxiv 2020 Nov;(): Fernandez-Castaneda A, bioRxiv 2022;(): Grandi A, bioRxiv 2021 Jul;(): Hassler L, bioRxiv 2021 Mar;(): King RG, bioRxiv 2020;(): Rice A, bioRxiv 2021 Mar;(): Rice A, bioRxiv 2021 Nov;(): Rice A, Sci Rep 2021 Jul 21;11(1):14917 Spencer AJ, bioRxiv 2021 Jan;(): Tummino TA, bioRxiv 2021 Mar;(): |
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CD1.129S-Stat1+/Cnbc | MGI:6119400 | congenic | Lassnig C, Proc Natl Acad Sci U S A 2005 Jun 7;102(23):8275-80 | J:99728 | HCoV-229E_virus | CD1.129S-Stat1+/Cnbccongenic |
Lassnig C, Proc Natl Acad Sci U S A 2005 Jun 7;102(23):8275-80 |
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CD1(129S)-Tg(ANPEP)270Mmul/Cnbc | MGI:6119398 | congenic|mutant strain|transgenic | Lassnig C, Proc Natl Acad Sci U S A 2005 Jun 7;102(23):8275-80 | J:99728 | HCoV-229E_virus | CD1(129S)-Tg(ANPEP)270Mmul/Cnbccongenic|mutant strain|transgenic |
Lassnig C, Proc Natl Acad Sci U S A 2005 Jun 7;102(23):8275-80 |
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CD1(129S)-Tg(ANPEP)861Mmul/Cnbc | MGI:6119399 | congenic|mutant strain|targeted mutation | Lassnig C, Proc Natl Acad Sci U S A 2005 Jun 7;102(23):8275-80 | J:99728 | HCoV-229E_virus | CD1(129S)-Tg(ANPEP)861Mmul/Cnbccongenic|mutant strain|targeted mutation |
Lassnig C, Proc Natl Acad Sci U S A 2005 Jun 7;102(23):8275-80 |
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CD1.Cg-Stat1tm1Dlv/Cnbc | MGI:6119401 | congenic|mutant strain|targeted mutation|transgenic | Lassnig C, Proc Natl Acad Sci U S A 2005 Jun 7;102(23):8275-80 | J:99728 | HCoV-229E_virus | CD1.Cg-Stat1tm1Dlv/Cnbccongenic|mutant strain|targeted mutation|transgenic |
Lassnig C, Proc Natl Acad Sci U S A 2005 Jun 7;102(23):8275-80 |
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CD1.Cg-Stat1tm1Dlv Tg(ANPEP)270Mmul/Cnbc | MGI:6120539 | congenic|mutant strain|targeted mutation|transgenic | Lassnig C, Proc Natl Acad Sci U S A 2005 Jun 7;102(23):8275-80 | J:99728 | HCoV-229E_virus | CD1.Cg-Stat1tm1Dlv Tg(ANPEP)270Mmul/Cnbccongenic|mutant strain|targeted mutation|transgenic |
Lassnig C, Proc Natl Acad Sci U S A 2005 Jun 7;102(23):8275-80 |
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CD1.Cg-Stat1tm1Dlv Tg(ANPEP)861Mmul/Cnbc | MGI:6120528 | congenic|mutant strain|targeted mutation|transgenic | Lassnig C, Proc Natl Acad Sci U S A 2005 Jun 7;102(23):8275-80 | J:99728 | HCoV-229E_virus | CD1.Cg-Stat1tm1Dlv Tg(ANPEP)861Mmul/Cnbccongenic|mutant strain|targeted mutation|transgenic |
Lassnig C, Proc Natl Acad Sci U S A 2005 Jun 7;102(23):8275-80 |
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Crl:CD-1 | MGI:5652673 | outbred stock | Wang Y, Invest Ophthalmol Vis Sci 1996 Jan;37(1):250-4 Wang Y, Invest Ophthalmol Vis Sci 2000 Sep;41(10):3011-8 | J:36900 J:64200 | Mouse_Hepatitis_virus Mouse_Hepatitis_virus|Pathology | Crl:CD-1outbred stock |
Wang Y, Invest Ophthalmol Vis Sci 1996 Jan;37(1):250-4 Wang Y, Invest Ophthalmol Vis Sci 2000 Sep;41(10):3011-8 |
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DBA/1J | MGI:2159759 | inbred strain | Shen ZT, Sci Rep 2016 Jun 28;6():28672 | J:291625 | SARS-CoV_virus | DBA/1Jinbred strain |
Shen ZT, Sci Rep 2016 Jun 28;6():28672 |
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DBA/2J | MGI:2684695 | inbred strain | Hassan AO, Cell 2020 Jun 10;(): Khanolkar A, J Virol 2009 Sep;83(17):8946-56 | J:290258 J:153918 | Infection|SARS-CoV-2_virus|Treatment Mouse_Hepatitis_virus|Pathology | DBA/2Jinbred strain |
Hassan AO, Cell 2020 Jun 10;(): Khanolkar A, J Virol 2009 Sep;83(17):8946-56 |
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(DBA/2J x B6.Cg-Tg(K18-ACE2)2Prlmn/J)F1/J | MGI:6865662 | F1 hybrid|mutant strain|transgenic | Robertson SJ, Nat Commun 2023 Jul 25;14(1):4481 | J:338561 | Infection|SARS-CoV-2_virus | (DBA/2J x B6.Cg-Tg(K18-ACE2)2Prlmn/J)F1/JF1 hybrid|mutant strain|transgenic |
Robertson SJ, Nat Commun 2023 Jul 25;14(1):4481 |
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FVB-Tg(Cdh5-tTA)D5Lbjn/J | MGI:4839338 | coisogenic|mutant strain|transgenic | Wu J, Immunity 2021 Nov 9;54(11):2632-2649.e6 | J:323769 | Gene|Pathology | FVB-Tg(Cdh5-tTA)D5Lbjn/Jcoisogenic|mutant strain|transgenic |
Wu J, Immunity 2021 Nov 9;54(11):2632-2649.e6 |
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ICR | MGI:2160272 | strain family | Rao L, Proc Natl Acad Sci U S A 2020 Nov 3;117(44):27141-27147 Sagawa T, Environ Res 2021 Apr;195():110722 Spencer AJ, bioRxiv 2021 Jan;(): | J:297098 J:305462 J:302146 | SARS-CoV-2_virus|Treatment Comorbidity|Gene SARS-CoV-2_virus|Vaccine | ICRstrain family |
Rao L, Proc Natl Acad Sci U S A 2020 Nov 3;117(44):27141-27147 Sagawa T, Environ Res 2021 Apr;195():110722 Spencer AJ, bioRxiv 2021 Jan;(): |
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ICR-Tg(Ace2-ACE2)1Cqin/J | MGI:6401293 | mutant stock|transgenic | Yang XH, Comp Med 2007 Oct;57(5):450-9 | J:141460 | Infection|SARS-CoV_virus | ICR-Tg(Ace2-ACE2)1Cqin/Jmutant stock|transgenic |
Yang XH, Comp Med 2007 Oct;57(5):450-9 |
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NOD.Cg-Prkdcscid Il2rgtm1Wjl Ace2tm1(ACE2)Dwnt/J | MGI:6865656 | congenic|mutant strain|spontaneous mutation|targeted mutation | Zhou B, bioRxiv 2020;(): | J:296356 | Infection|SARS-CoV-2_virus | NOD.Cg-Prkdcscid Il2rgtm1Wjl Ace2tm1(ACE2)Dwnt/Jcongenic|mutant strain|spontaneous mutation|targeted mutation |
Zhou B, bioRxiv 2020;(): |
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NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ | MGI:3577020 | congenic|mutant strain|spontaneous mutation|targeted mutation | Harb H, Immunity 2021 Apr 22;(): | J:347529 | Infection | NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJcongenic|mutant strain|spontaneous mutation|targeted mutation |
Harb H, Immunity 2021 Apr 22;(): |
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NOD.Cg-Rag1tm1Mom Il2rgtm1Wjl/SzJ | MGI:3804477 | congenic|targeted mutation | Halwe S, bioRxiv 2021 Jun;(): Ngo VL, Cell Host Microbe 2024 Jan 23;(): | J:308648 J:345954 | SARS-CoV-2_virus|Treatment|VOC_B.1.1.7_Alpha|VOC_B.1.351_Beta Infection|MERS-CoV-MA_virus | NOD.Cg-Rag1tm1Mom Il2rgtm1Wjl/SzJcongenic|targeted mutation |
Halwe S, bioRxiv 2021 Jun;(): Ngo VL, Cell Host Microbe 2024 Jan 23;(): |
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NOD/ShiLtJ | MGI:2162056 | inbred strain | Gralinski LE, PLoS Genet 2015 Oct;11(10):e1005504 Josset L, RNA Biol 2014;11(7):875-90 Xiong H, G3 (Bethesda) 2014 Jun 5;4(8):1429-44 | J:268979 J:276026 J:276183 | Infection|SARS-CoV-MA_virus SARS-CoV-MA_virus | NOD/ShiLtJinbred strain |
Gralinski LE, PLoS Genet 2015 Oct;11(10):e1005504 Josset L, RNA Biol 2014;11(7):875-90 Xiong H, G3 (Bethesda) 2014 Jun 5;4(8):1429-44 |
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(NOD/ShiLtJ x B6.Cg-Tg(K18-ACE2)2Prlmn/J)F1/J | MGI:6865671 | F1 hybrid|mutant strain|transgenic | Robertson SJ, Nat Commun 2023 Jul 25;14(1):4481 | J:338561 | Infection|SARS-CoV-2_virus | (NOD/ShiLtJ x B6.Cg-Tg(K18-ACE2)2Prlmn/J)F1/JF1 hybrid|mutant strain|transgenic |
Robertson SJ, Nat Commun 2023 Jul 25;14(1):4481 |
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NZB/BlNJ | MGI:2180844 | inbred strain | Khanolkar A, J Virol 2009 Sep;83(17):8946-56 | J:153918 | Mouse_Hepatitis_virus|Pathology | NZB/BlNJinbred strain |
Khanolkar A, J Virol 2009 Sep;83(17):8946-56 |
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NZO/HlLtJ | MGI:2173835 | inbred strain | MGI:5902927 | immune system | MP:0005387 | Gralinski LE, PLoS Genet 2015 Oct;11(10):e1005504 Josset L, RNA Biol 2014;11(7):875-90 Xiong H, G3 (Bethesda) 2014 Jun 5;4(8):1429-44 | J:268979 J:276026 J:276183 | Infection|SARS-CoV-MA_virus SARS-CoV-MA_virus | NZO/HlLtJinbred strain |
MGI:5902927 | immune system |
Gralinski LE, PLoS Genet 2015 Oct;11(10):e1005504 Josset L, RNA Biol 2014;11(7):875-90 Xiong H, G3 (Bethesda) 2014 Jun 5;4(8):1429-44 |
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(NZO/HlLtJ x B6.Cg-Tg(K18-ACE2)2Prlmn/J)F1/J | MGI:6865670 | F1 hybrid|mutant strain|transgenic | Robertson SJ, Nat Commun 2023 Jul 25;14(1):4481 | J:338561 | Infection|SARS-CoV-2_virus | (NZO/HlLtJ x B6.Cg-Tg(K18-ACE2)2Prlmn/J)F1/JF1 hybrid|mutant strain|transgenic |
Robertson SJ, Nat Commun 2023 Jul 25;14(1):4481 |
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PWK/PhJ | MGI:2160654 | inbred strain|wild-derived | MGI:5902923 | immune system mortality/aging | MP:0005387 MP:0010768 | Gralinski LE, PLoS Genet 2015 Oct;11(10):e1005504 Josset L, RNA Biol 2014;11(7):875-90 Peng X, mBio 2010 Oct 26;1(5): Peng X, mBio 2011;2(6): Xiong H, G3 (Bethesda) 2014 Jun 5;4(8):1429-44 | J:268979 J:276026 J:276986 J:276989 J:276183 | Infection|SARS-CoV-MA_virus SARS-CoV-MA_virus | PWK/PhJinbred strain|wild-derived |
MGI:5902923 | immune system mortality/aging |
Gralinski LE, PLoS Genet 2015 Oct;11(10):e1005504 Josset L, RNA Biol 2014;11(7):875-90 Peng X, mBio 2010 Oct 26;1(5): Peng X, mBio 2011;2(6): Xiong H, G3 (Bethesda) 2014 Jun 5;4(8):1429-44 |
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(PWK/PhJ x B6.Cg-Tg(K18-ACE2)2Prlmn/J)F1/J | MGI:6865668 | F1 hybrid|mutant strain|transgenic | Robertson SJ, Nat Commun 2023 Jul 25;14(1):4481 | J:338561 | Infection|SARS-CoV-2_virus | (PWK/PhJ x B6.Cg-Tg(K18-ACE2)2Prlmn/J)F1/JF1 hybrid|mutant strain|transgenic |
Robertson SJ, Nat Commun 2023 Jul 25;14(1):4481 |
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SJL | MGI:2159833 | strain family | Compton SR, Virology 1994 Aug 15;203(1):197-201 | J:19444 | Infection|Mouse_Hepatitis_virus | SJLstrain family |
Compton SR, Virology 1994 Aug 15;203(1):197-201 |
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SJL/J | MGI:2159739 | inbred strain | MGI:3719417 | Ceacam1Hv2-r | MGI:3053078 | Spontaneous | immune system | MP:0005387 | Barthold SW, Lab Anim Sci 1993 Aug;43(4):276-84 Dveksler GS, J Virol 1993 Jan;67(1):1-8 Stohlman SA, J Immunol 1980 Apr;124(4):1733-9 Williams RK, Proc Natl Acad Sci U S A 1991 Jul 1;88(13):5533-6 Yokomori K, J Virol 1992 Dec;66(12):6931-8 | J:14457 J:92495 J:25384 J:25438 J:3241 | Infection|Mouse_Hepatitis_virus Mouse_Hepatitis_virus | SJL/Jinbred strain |
MGI:3719417 | immune system |
Barthold SW, Lab Anim Sci 1993 Aug;43(4):276-84 Dveksler GS, J Virol 1993 Jan;67(1):1-8 Stohlman SA, J Immunol 1980 Apr;124(4):1733-9 Williams RK, Proc Natl Acad Sci U S A 1991 Jul 1;88(13):5533-6 Yokomori K, J Virol 1992 Dec;66(12):6931-8 |
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STOCK Hopxtm2.1(cre/ERT2)Joe/J | MGI:5320285 | mutant stock|targeted mutation | Tang AT, PLoS Biol 2023 Feb;21(2):e3001989 | J:337814 | Pathology|SARS-CoV-2_virus|VOC_B.1.1.529_Omicron | STOCK Hopxtm2.1(cre/ERT2)Joe/Jmutant stock|targeted mutation |
Tang AT, PLoS Biol 2023 Feb;21(2):e3001989 |
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STOCK Tg(Actl6b-Cre)4092Jiwu/J | MGI:5699265 | mutant stock|transgenic | Tang AT, PLoS Biol 2023 Feb;21(2):e3001989 | J:337814 | Pathology|SARS-CoV-2_virus|VOC_B.1.1.529_Omicron | STOCK Tg(Actl6b-Cre)4092Jiwu/Jmutant stock|transgenic |
Tang AT, PLoS Biol 2023 Feb;21(2):e3001989 |
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STOCK Tg(Mx1-cre)1Cgn/J | MGI:2162199 | mutant stock|transgenic | Bombaci G, Life Sci Alliance 2022 Jun;5(6):e202101226 | J:331827 | SARS-CoV-2_virus | STOCK Tg(Mx1-cre)1Cgn/Jmutant stock|transgenic |
Bombaci G, Life Sci Alliance 2022 Jun;5(6):e202101226 |
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Swiss albino | MGI:5652853 | outbred stock | Saleh AA, bioRxiv 2021 Mar;(): | J:302705 | SARS-CoV-2_virus|Vaccine | Swiss albinooutbred stock |
Saleh AA, bioRxiv 2021 Mar;(): |
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Swiss Webster | MGI:2160840 | outbred stock | Lai CY, bioRxiv 2021 Mar;(): Ngo VL, Cell Host Microbe 2024 Jan 23;(): Staquicini DI, bioRxiv 2021 Mar;(): | J:302709 J:345954 J:302940 | SARS-CoV-2_virus|Vaccine Infection|MERS-CoV-MA_virus | Swiss Websteroutbred stock |
Lai CY, bioRxiv 2021 Mar;(): Ngo VL, Cell Host Microbe 2024 Jan 23;(): Staquicini DI, bioRxiv 2021 Mar;(): |
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WSB/EiJ | MGI:2160667 | inbred strain|wild-derived | MGI:5818477 | immune system mortality/aging | MP:0005387 MP:0010768 | Gralinski LE, PLoS Genet 2015 Oct;11(10):e1005504 Josset L, RNA Biol 2014;11(7):875-90 Peng X, mBio 2010 Oct 26;1(5): Peng X, mBio 2011;2(6): Xiong H, G3 (Bethesda) 2014 Jun 5;4(8):1429-44 | J:268979 J:276026 J:276986 J:276989 J:276183 | Infection|SARS-CoV-MA_virus SARS-CoV-MA_virus | WSB/EiJinbred strain|wild-derived |
MGI:5818477 | immune system mortality/aging |
Gralinski LE, PLoS Genet 2015 Oct;11(10):e1005504 Josset L, RNA Biol 2014;11(7):875-90 Peng X, mBio 2010 Oct 26;1(5): Peng X, mBio 2011;2(6): Xiong H, G3 (Bethesda) 2014 Jun 5;4(8):1429-44 |
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(WSB/EiJ x B6.Cg-Tg(K18-ACE2)2Prlmn/J)F1/J | MGI:6865667 | F1 hybrid|mutant strain|transgenic | Robertson SJ, Nat Commun 2023 Jul 25;14(1):4481 | J:338561 | Infection|SARS-CoV-2_virus | (WSB/EiJ x B6.Cg-Tg(K18-ACE2)2Prlmn/J)F1/JF1 hybrid|mutant strain|transgenic |
Robertson SJ, Nat Commun 2023 Jul 25;14(1):4481 |
Alleles for Laboratory Mouse Strains Used in Coronavirus Research
1-allele | 2-mgi | 3-type | 4-subtypes | 5-geno-id | 6-do-term | 7-do-id | 8-mp-term | 9-mp-id | 10-cite | 11-jnum | 12-tags | Allele | Genotype Details | Human Disease and Mouse Phenotype Categories | References | Keywords |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Ace2em1(ACE2)Gpt | MGI:6452437 | Endonuclease-mediated | Inserted expressed sequence | Li C, Cell 2022 Apr 14;185(8):1389-1401.e18 Liu D, Proc Natl Acad Sci U S A 2023 Jan 24;120(4):e2202820120 | J:324335 J:340364 | SARS-CoV-2_virus|Treatment|VOC_B.1.1.529_Omicron SARS-CoV-2_virus|VOC_B.1.351_Beta | Ace2em1(ACE2)GptEndonuclease-mediated |
Li C, Cell 2022 Apr 14;185(8):1389-1401.e18 Liu D, Proc Natl Acad Sci U S A 2023 Jan 24;120(4):e2202820120 |
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Ace2em1(ACE2)Mlkn | MGI:6842318 | Endonuclease-mediated | Conditional ready|Humanized sequence|Inserted expressed sequence|Null/knockout | Tang AT, bioRxiv 2021 Dec;(): Tang AT, PLoS Biol 2023 Feb;21(2):e3001989 Gao S, Front Cardiovasc Med 2023;10():1266276 | J:315719 J:337814 J:346048 | Pathology|SARS-CoV-2_virus Pathology|SARS-CoV-2_virus|VOC_B.1.1.529_Omicron Infection|SARS-CoV-2_virus | Ace2em1(ACE2)MlknEndonuclease-mediated |
Tang AT, bioRxiv 2021 Dec;(): Tang AT, PLoS Biol 2023 Feb;21(2):e3001989 Gao S, Front Cardiovasc Med 2023;10():1266276 |
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Ace2em1(ACE2)Rlu | MGI:7524682 | Endonuclease-mediated | Humanized sequence|Inserted expressed sequence | Romero MJ, Front Immunol 2023;14():1241448 | J:339692 | SARS-CoV-2_virus | Ace2em1(ACE2)RluEndonuclease-mediated |
Romero MJ, Front Immunol 2023;14():1241448 |
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Ace2em1(ACE2)Yowa | MGI:6431336 | Endonuclease-mediated | Humanized sequence|Null/knockout|Reporter | MGI:6431340 | COVID-19 | DOID:0080600 | cardiovascular system homeostasis/metabolism immune system respiratory system | MP:0005385 MP:0005376 MP:0005387 MP:0005388 | Sun SH, Cell Host Microbe 2020;20():1-10 Wu Y, Science 2020 Jun 12;368(6496):1274-1278 Yang J, Nature 2020 Jul 29;(): Singh A, Virol Sin 2020 Jun;35(3):290-304 Johansen MD, Mucosal Immunol 2020 Aug 20;(): Munoz-Fontela C, Nature 2020 Sep 23;(): Ye Q, bioRxiv 2020 Nov;(): Pinto D, bioRxiv 2020 Apr 9;(): Zhu L, bioRxiv 2020 Nov;(): Gurumurthy CB, Nat Protoc 2020 Dec;15(12):3777-3787 Chen J, bioRxiv 2021 Nov;(): | J:288243 J:290802 J:292665 J:295349 J:295350 J:295351 J:296708 J:297123 J:298147 J:298750 J:315718 | Infection|Pathology|SARS-CoV-2_virus SARS-CoV-2_virus|Treatment SARS-CoV-2_virus|Vaccine MERS-CoV-MA_virus|MERS-CoV_virus|SARS-CoV-2-MA_virus|SARS-CoV-2_virus|SARS-CoV_virus MERS-CoV-MA_virus|MERS-CoV_virus|SARS-CoV-2-MA_virus|SARS-CoV-2_virus|SARS-CoV-MA_virus|SARS-CoV_virus SARS-CoV-2-MA_virus|SARS-CoV-2_virus|SARS-CoV_virus Pathology|SARS-CoV-2_virus SARS-CoV-2-MA_virus|SARS-CoV-2_virus|Treatment SARS-CoV-2_virus | Ace2em1(ACE2)YowaEndonuclease-mediated |
MGI:6431340 | cardiovascular system homeostasis/metabolism immune system respiratory system COVID-19 |
Sun SH, Cell Host Microbe 2020;20():1-10 Wu Y, Science 2020 Jun 12;368(6496):1274-1278 Yang J, Nature 2020 Jul 29;(): Singh A, Virol Sin 2020 Jun;35(3):290-304 Johansen MD, Mucosal Immunol 2020 Aug 20;(): Munoz-Fontela C, Nature 2020 Sep 23;(): Ye Q, bioRxiv 2020 Nov;(): Pinto D, bioRxiv 2020 Apr 9;(): Zhu L, bioRxiv 2020 Nov;(): Gurumurthy CB, Nat Protoc 2020 Dec;15(12):3777-3787 Chen J, bioRxiv 2021 Nov;(): |
Ace2em1Cya | MGI:6500740 | Endonuclease-mediated | Null/knockout | MGI:6500742 | cellular digestive/alimentary system growth/size/body homeostasis/metabolism immune system | MP:0005384 MP:0005381 MP:0005378 MP:0005376 MP:0005387 | Yu W, Biochem Biophys Res Commun 2020 Dec 17;533(4):1276-1282 | J:299383 | Gene | Ace2em1CyaEndonuclease-mediated |
MGI:6500742 | cellular digestive/alimentary system growth/size/body homeostasis/metabolism immune system |
Yu W, Biochem Biophys Res Commun 2020 Dec 17;533(4):1276-1282 |
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Ace2em1Diam | MGI:7398548 | Endonuclease-mediated | Null/knockout | Winkler ES, J Virol 2022 Jan 12;96(1):e0151121 | J:331773 | Infection|SARS-CoV-2_virus|VOC_B.1.1.7_Alpha|VOC_B.1.351_Beta | Ace2em1DiamEndonuclease-mediated |
Winkler ES, J Virol 2022 Jan 12;96(1):e0151121 |
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Ace2em1Guru | MGI:6763023 | Endonuclease-mediated | Humanized sequence | Gurumurthy CB, Nat Protoc 2020 Dec;15(12):3777-3787 | J:298750 | SARS-CoV-2_virus | Ace2em1GuruEndonuclease-mediated |
Gurumurthy CB, Nat Protoc 2020 Dec;15(12):3777-3787 |
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Ace2em1Mccc | MGI:7468713 | Endonuclease-mediated | Humanized sequence | Nakandakari-Higa S, Front Immunol 2022;13():1007080 | J:335150 | Infection|SARS-CoV-2_virus|VOC_B.1.1.529_Omicron | Ace2em1McccEndonuclease-mediated |
Nakandakari-Higa S, Front Immunol 2022;13():1007080 |
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Ace2em1Qhs | MGI:6415670 | Endonuclease-mediated | Null/knockout | Jia H, Nat Commun 2020 Oct 14;11(1):5165 | J:296535 | SARS-CoV-2_virus | Ace2em1QhsEndonuclease-mediated |
Jia H, Nat Commun 2020 Oct 14;11(1):5165 |
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Ace2em1Smoc | MGI:6415213 | Endonuclease-mediated | Null/knockout | Qin WH, Cell Mol Gastroenterol Hepatol 2021;12(4):1514-1516.e4 Li D, J Med Virol 2022 Oct;94(10):4878-4889 | J:319435 J:339217 | Gene|Infection Infection|SARS-CoV-2_virus | Ace2em1SmocEndonuclease-mediated |
Qin WH, Cell Mol Gastroenterol Hepatol 2021;12(4):1514-1516.e4 Li D, J Med Virol 2022 Oct;94(10):4878-4889 |
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Ace2em2(ACE2/GFP)Mlkn | MGI:6842319 | Endonuclease-mediated | Conditional ready|Humanized sequence|Inserted expressed sequence|Null/knockout|Reporter | Tang AT, bioRxiv 2021 Dec;(): | J:315719 | Pathology|SARS-CoV-2_virus | Ace2em2(ACE2/GFP)MlknEndonuclease-mediated |
Tang AT, bioRxiv 2021 Dec;(): |
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Ace2em2(ACE2)Gpt | MGI:6452442 | Endonuclease-mediated | Inserted expressed sequence | MGI:6514876 | growth/size/body immune system respiratory system | MP:0005378 MP:0005387 MP:0005388 | Wu X, bioRxiv 2021 Feb;(): | J:302150 | SARS-CoV-2_virus|Treatment | Ace2em2(ACE2)GptEndonuclease-mediated |
MGI:6514876 | growth/size/body immune system respiratory system |
Wu X, bioRxiv 2021 Feb;(): |
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Ace2em2(ACE2)Mlkn | MGI:7507528 | Endonuclease-mediated | Conditional ready|Humanized sequence|Inserted expressed sequence|Null/knockout | Tang AT, PLoS Biol 2023 Feb;21(2):e3001989 | J:337814 | Pathology|SARS-CoV-2_virus|VOC_B.1.1.529_Omicron | Ace2em2(ACE2)MlknEndonuclease-mediated |
Tang AT, PLoS Biol 2023 Feb;21(2):e3001989 |
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Ace2em2Guru | MGI:6763025 | Endonuclease-mediated | Humanized sequence | Gurumurthy CB, Nat Protoc 2020 Dec;15(12):3777-3787 | J:298750 | SARS-CoV-2_virus | Ace2em2GuruEndonuclease-mediated |
Gurumurthy CB, Nat Protoc 2020 Dec;15(12):3777-3787 |
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Ace2em2Mccc | MGI:7468714 | Endonuclease-mediated | Humanized sequence | Nakandakari-Higa S, Front Immunol 2022;13():1007080 | J:335150 | Infection|SARS-CoV-2_virus|VOC_B.1.1.529_Omicron | Ace2em2McccEndonuclease-mediated |
Nakandakari-Higa S, Front Immunol 2022;13():1007080 |
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Ace2em2Shyy | MGI:6406965 | Endonuclease-mediated | Not Specified | Jia H, Nat Commun 2020 Oct 14;11(1):5165 | J:296535 | SARS-CoV-2_virus | Ace2em2ShyyEndonuclease-mediated |
Jia H, Nat Commun 2020 Oct 14;11(1):5165 |
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Ace2em#Yngh | MGI:5752578 | Endonuclease-mediated | Null/knockout | Jia H, Nat Commun 2020 Oct 14;11(1):5165 | J:296535 | SARS-CoV-2_virus | Ace2em#YnghEndonuclease-mediated |
Jia H, Nat Commun 2020 Oct 14;11(1):5165 |
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Ace2tm1(ACE2)Dwnt | MGI:6469881 | Targeted | Humanized sequence|Inserted expressed sequence | Zhou B, bioRxiv 2020;(): Zhou B, Nature 2021 Apr;592(7852):122-127 Ulrich L, bioRxiv 2021 Jun;(): Winkler ES, J Virol 2022 Jan 12;96(1):e0151121 Perico L, Sci Rep 2023 Jul 14;13(1):11392 Tada T, Proc Natl Acad Sci U S A 2023 Jun 6;120(23):e2303509120 | J:296356 J:305777 J:308620 J:331773 J:338324 J:338414 | Infection|SARS-CoV-2_virus Infection|SARS-CoV-2_virus|VOC_B.1.1.7_Alpha|VOC_B.1.351_Beta Pathology|SARS-CoV-2_virus|Treatment SARS-CoV-2_virus|Treatment|VOC_B.1.1.529_Omicron | Ace2tm1(ACE2)DwntTargeted |
Zhou B, bioRxiv 2020;(): Zhou B, Nature 2021 Apr;592(7852):122-127 Ulrich L, bioRxiv 2021 Jun;(): Winkler ES, J Virol 2022 Jan 12;96(1):e0151121 Perico L, Sci Rep 2023 Jul 14;13(1):11392 Tada T, Proc Natl Acad Sci U S A 2023 Jun 6;120(23):e2303509120 |
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Ace2tm1a(KOMP)Wtsi | MGI:4820112 | Targeted | Conditional ready|Null/knockout|Reporter | Jia H, Nat Commun 2020 Oct 14;11(1):5165 | J:296535 | SARS-CoV-2_virus | Ace2tm1a(KOMP)WtsiTargeted |
Jia H, Nat Commun 2020 Oct 14;11(1):5165 |
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Ace2tm1c(KOMP)Wtsi | MGI:6415205 | Targeted | Conditional ready | Jia H, Nat Commun 2020 Oct 14;11(1):5165 | J:296535 | SARS-CoV-2_virus | Ace2tm1c(KOMP)WtsiTargeted |
Jia H, Nat Commun 2020 Oct 14;11(1):5165 |
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Ace2tm1Cof | MGI:3665270 | Targeted | Null/knockout | Ji H, Hypertension 2020 Aug;76(2):478-487 Jia H, Nat Commun 2020 Oct 14;11(1):5165 | J:290256 J:296535 | Gene SARS-CoV-2_virus | Ace2tm1CofTargeted |
Ji H, Hypertension 2020 Aug;76(2):478-487 Jia H, Nat Commun 2020 Oct 14;11(1):5165 |
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Ace2tm1Hira | MGI:3794966 | Targeted | Null/knockout | Jia H, Nat Commun 2020 Oct 14;11(1):5165 Wang Y, FASEB J 2021 Mar;35(3):e21419 | J:296535 J:309535 | SARS-CoV-2_virus Gene | Ace2tm1HiraTargeted |
Jia H, Nat Commun 2020 Oct 14;11(1):5165 |
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Ace2tm1Lex | MGI:5007005 | Targeted | Null/knockout | Jia H, Nat Commun 2020 Oct 14;11(1):5165 Bilinska K, bioRxiv 2021 Apr;(): | J:296535 J:304622 | SARS-CoV-2_virus Gene | Ace2tm1LexTargeted |
Jia H, Nat Commun 2020 Oct 14;11(1):5165 |
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Ace2tm1Pngr | MGI:2661723 | Targeted | Null/knockout | MGI:5912243 MGI:6402915 | cardiovascular system immune system | MP:0005385 MP:0005387 | Kuba K, Nat Med 2005 Aug;11(8):875-9 Mullick JB, Cell Mol Bioeng 2020 Jul 27;():1-11 Jia H, Nat Commun 2020 Oct 14;11(1):5165 Gawish R, Elife 2022 Jan 13;11():e74623 | J:286299 J:294026 J:296535 J:318828 | Infection|SARS-CoV_virus SARS-CoV-2_virus|SARS-CoV_virus SARS-CoV-2_virus Pathology|SARS-CoV-2-MA_virus | Ace2tm1PngrTargeted |
MGI:5912243 MGI:6402915 | cardiovascular system immune system |
Kuba K, Nat Med 2005 Aug;11(8):875-9 Mullick JB, Cell Mol Bioeng 2020 Jul 27;():1-11 Jia H, Nat Commun 2020 Oct 14;11(1):5165 Gawish R, Elife 2022 Jan 13;11():e74623 |
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Acetm4Keb | MGI:2665017 | Targeted | Null/knockout | Wysocki J, J Am Soc Nephrol 2020 Sep;31(9):1941-1943 | J:294060 | SARS-CoV-2_virus | Acetm4KebTargeted |
Wysocki J, J Am Soc Nephrol 2020 Sep;31(9):1941-1943 |
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Acetm7Keb | MGI:3783350 | Targeted | Modified isoform(s) | Wysocki J, J Am Soc Nephrol 2020 Sep;31(9):1941-1943 | J:294060 | SARS-CoV-2_virus | Acetm7KebTargeted |
Wysocki J, J Am Soc Nephrol 2020 Sep;31(9):1941-1943 |
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Adartm1.1Phs | MGI:3828307 | Targeted | Conditional ready|No functional change | Adamska JZ, Cell Rep 2023 Jan 31;42(1):112038 | J:333092 | Gene|VOC_B.1.351_Beta | Adartm1.1PhsTargeted |
Adamska JZ, Cell Rep 2023 Jan 31;42(1):112038 |
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Adh5Gt(IST12290F1)Tigm | MGI:4065198 | Gene trapped | Null/knockout|Reporter | Kim J, Front Pharmacol 2023;14():1304697 | J:343781 | SARS-CoV-2_virus|Treatment | Adh5Gt(IST12290F1)TigmGene trapped |
Kim J, Front Pharmacol 2023;14():1304697 |
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Aicdatm1.1(cre/ERT2)Crey | MGI:4437052 | Targeted | Inducible|Null/knockout|Recombinase | Gregoire C, bioRxiv 2021 Dec;(): | J:316768 | SARS-CoV-2_virus | Aicdatm1.1(cre/ERT2)CreyTargeted |
Gregoire C, bioRxiv 2021 Dec;(): |
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Aicdatm1Hon | MGI:2156156 | Targeted | Null/knockout | Luo Y, Signal Transduct Target Ther 2022 Jan 4;7(1):7 | J:333746 | SARS-CoV-2_virus|Vaccine | Aicdatm1HonTargeted |
Luo Y, Signal Transduct Target Ther 2022 Jan 4;7(1):7 |
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Aim2tm1.1Vmd | MGI:5428935 | Targeted | Null/knockout | Zheng M, J Biol Chem 2020 Oct 9;295(41):14040-14052 | J:298138 | Mouse_Hepatitis_virus | Aim2tm1.1VmdTargeted |
Zheng M, J Biol Chem 2020 Oct 9;295(41):14040-14052 |
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Apaf1tm1Her | MGI:1860245 | Targeted | Null/knockout | Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 | J:296686 | Pathology|SARS-CoV-2_virus|Treatment | Apaf1tm1HerTargeted |
Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 |
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Apoetm1(APOE*2)Mae | MGI:2158396 | Targeted | Humanized sequence|Inserted expressed sequence | Ostendorf BN, Nature 2022 Nov;611(7935):346-351 | J:340480 | Gene|SARS-CoV-2-MA_virus | Apoetm1(APOE*2)MaeTargeted |
Ostendorf BN, Nature 2022 Nov;611(7935):346-351 |
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Apoetm2(APOE*3)Mae | MGI:2157240 | Targeted | Humanized sequence|Inserted expressed sequence|Modified isoform(s)|Null/knockout | Rhea EM, Nat Neurosci 2021 Mar;24(3):368-378 | J:305558 | SARS-CoV-2_virus | Apoetm2(APOE*3)MaeTargeted |
Rhea EM, Nat Neurosci 2021 Mar;24(3):368-378 |
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Apoetm3(APOE*4)Mae | MGI:2158398 | Targeted | Humanized sequence|Inserted expressed sequence | Rhea EM, Nat Neurosci 2021 Mar;24(3):368-378 Ostendorf BN, Nature 2022 Nov;611(7935):346-351 | J:305558 J:340480 | SARS-CoV-2_virus Gene|SARS-CoV-2-MA_virus | Apoetm3(APOE*4)MaeTargeted |
Rhea EM, Nat Neurosci 2021 Mar;24(3):368-378 Ostendorf BN, Nature 2022 Nov;611(7935):346-351 |
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Apptm3.1Tcs | MGI:5637817 | Targeted | Humanized sequence | Magusali N, bioRxiv 2021 Mar;(): | J:303205 | Comorbidity | Apptm3.1TcsTargeted |
Magusali N, bioRxiv 2021 Mar;(): |
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Atg5tm1Myok | MGI:3663625 | Targeted | Conditional ready|No functional change | Zhao Z, Autophagy 2007 Nov-Dec;3(6):581-5 | J:282479 | Mouse_Hepatitis_virus | Atg5tm1MyokTargeted |
Zhao Z, Autophagy 2007 Nov-Dec;3(6):581-5 |
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B2mtm1Unc | MGI:1857133 | Targeted | Null/knockout | Brentville VA, bioRxiv 2021 Jun;(): Houtman JJ, J Neurovirol 1996 APR;2(2):101-110 Lavi E, Pathobiology 1999 Mar-Apr;67(2):75-83 | J:308658 J:33974 J:54035 | SARS-CoV-2_virus|Vaccine Mouse_Hepatitis_virus Mouse_Hepatitis_virus|Pathology | B2mtm1UncTargeted |
Brentville VA, bioRxiv 2021 Jun;(): Houtman JJ, J Neurovirol 1996 APR;2(2):101-110 Lavi E, Pathobiology 1999 Mar-Apr;67(2):75-83 |
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Batf3tm1Kmm | MGI:3817232 | Targeted | Null/knockout | Ndeupen S, bioRxiv 2021 Aug;(): Ngo VL, Cell Host Microbe 2024 Jan 23;(): | J:308580 J:345954 | SARS-CoV-2_virus|Vaccine Infection|MERS-CoV-MA_virus | Batf3tm1KmmTargeted |
Ndeupen S, bioRxiv 2021 Aug;(): Ngo VL, Cell Host Microbe 2024 Jan 23;(): |
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Bcl6tm1.1Dent | MGI:5518542 | Targeted | Conditional ready|No functional change | Chen JS, bioRxiv 2021 Jun;(): | J:308655 | SARS-CoV-2_virus|VOC_B.1.351_Beta | Bcl6tm1.1DentTargeted |
Chen JS, bioRxiv 2021 Jun;(): |
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Bsgtm1(BSG)Smoc | MGI:6430241 | Targeted | Humanized sequence|Inserted expressed sequence | Geng J, bioRxiv 2021 May;(): | J:308748 | SARS-CoV-2_virus | Bsgtm1(BSG)SmocTargeted |
Geng J, bioRxiv 2021 May;(): |
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C1qatm1d(EUCOMM)Wtsi | MGI:6151469 | Targeted | Null/knockout | Ngo VL, Cell Host Microbe 2024 Jan 23;(): | J:345954 | Infection|MERS-CoV-MA_virus | C1qatm1d(EUCOMM)WtsiTargeted |
Ngo VL, Cell Host Microbe 2024 Jan 23;(): |
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C3tm1Crr | MGI:1861799 | Targeted | Null/knockout | MGI:3799624 | homeostasis/metabolism immune system nervous system vision/eye | MP:0005376 MP:0005387 MP:0003631 MP:0005391 | Gralinski LE, mBio 2018 Oct 9;9(5): | J:286325 | Pathology|SARS-CoV-MA_virus | C3tm1CrrTargeted |
MGI:3799624 | homeostasis/metabolism immune system nervous system vision/eye |
Gralinski LE, mBio 2018 Oct 9;9(5): |
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C4btm1Crr | MGI:1889070 | Targeted | Null/knockout | MGI:5296003 | homeostasis/metabolism immune system renal/urinary system | MP:0005376 MP:0005387 MP:0005367 | Gralinski LE, mBio 2018 Oct 9;9(5): | J:286325 | Pathology|SARS-CoV-MA_virus | C4btm1CrrTargeted |
MGI:5296003 | homeostasis/metabolism immune system renal/urinary system |
Gralinski LE, mBio 2018 Oct 9;9(5): |
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C5ar1tm1.1(C5AR1)Cmac | MGI:6449073 | Targeted | Humanized sequence|Inserted expressed sequence|Null/knockout | Carvelli J, Nature 2020 Jul 29;(): | J:291890 | Pathology|SARS-CoV-2_virus|Treatment | C5ar1tm1.1(C5AR1)CmacTargeted |
Carvelli J, Nature 2020 Jul 29;(): |
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Casp1tm1Flv | MGI:2158744 | Targeted | Null/knockout | Yang J, Nature 2020 Jul 29;(): Zheng M, J Biol Chem 2020 Oct 9;295(41):14040-14052 Wu J, Immunity 2021 Nov 9;54(11):2632-2649.e6 Duhalde Vega M, Sci Adv 2022 Sep 23;8(38):eabn6545 Zalinger ZB, J Neurovirol 2017 Dec;23(6):845-854 | J:292665 J:298138 J:323769 J:331762 J:331829 | SARS-CoV-2_virus|Vaccine Mouse_Hepatitis_virus Gene|Pathology | Casp1tm1FlvTargeted |
Yang J, Nature 2020 Jul 29;(): Zheng M, J Biol Chem 2020 Oct 9;295(41):14040-14052 Wu J, Immunity 2021 Nov 9;54(11):2632-2649.e6 Duhalde Vega M, Sci Adv 2022 Sep 23;8(38):eabn6545 Zalinger ZB, J Neurovirol 2017 Dec;23(6):845-854 |
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Casp1tm1Gne | MGI:5882087 | Targeted | Null/knockout | Kim E, Proc Natl Acad Sci U S A 2021 Aug 24;118(34):e2102435118 | J:313327 | SARS-CoV-2_virus|Vaccine | Casp1tm1GneTargeted |
Kim E, Proc Natl Acad Sci U S A 2021 Aug 24;118(34):e2102435118 |
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Casp1tm1Sesh | MGI:1927822 | Targeted | Null/knockout | Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 | J:296686 | Pathology|SARS-CoV-2_virus|Treatment | Casp1tm1SeshTargeted |
Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 |
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Casp3tm1Flv | MGI:2158753 | Targeted | Null/knockout | Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 | J:296686 | Pathology|SARS-CoV-2_virus|Treatment | Casp3tm1FlvTargeted |
Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 |
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Casp4del | MGI:5473345 | Spontaneous | Null/knockout | Zheng M, J Biol Chem 2020 Oct 9;295(41):14040-14052 | J:298138 | Mouse_Hepatitis_virus | Casp4delSpontaneous |
Zheng M, J Biol Chem 2020 Oct 9;295(41):14040-14052 |
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Casp4tm1.1Vmd | MGI:5468949 | Targeted | Null/knockout | Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 | J:296686 | Pathology|SARS-CoV-2_virus|Treatment | Casp4tm1.1VmdTargeted |
Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 |
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Casp4tm1Yuan | MGI:2159366 | Targeted | Null/knockout | Eltobgy M, bioRxiv 2021;(): Eltobgy MM, Proc Natl Acad Sci U S A 2022 May 24;119(21):e2202012119 | J:311911 J:331823 | Gene|SARS-CoV-2-MA_virus Gene|SARS-CoV-2-MA_virus|SARS-CoV-2_virus | Casp4tm1YuanTargeted |
Eltobgy M, bioRxiv 2021;(): Eltobgy MM, Proc Natl Acad Sci U S A 2022 May 24;119(21):e2202012119 |
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Casp7tm1Flv | MGI:3603317 | Targeted | Null/knockout | Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 | J:296686 | Pathology|SARS-CoV-2_virus|Treatment | Casp7tm1FlvTargeted |
Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 |
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Casp8tm1.1Raz | MGI:5546196 | Targeted | Null/knockout | Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 Zheng M, J Biol Chem 2020 Oct 9;295(41):14040-14052 | J:296686 J:298138 | Pathology|SARS-CoV-2_virus|Treatment Mouse_Hepatitis_virus | Casp8tm1.1RazTargeted |
Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 Zheng M, J Biol Chem 2020 Oct 9;295(41):14040-14052 |
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Ccl2tm1Rol | MGI:2175911 | Targeted | Null/knockout | Held KS, Virology 2004 Nov 24;329(2):251-60 | J:102446 | Infection|Mouse_Hepatitis_virus | Ccl2tm1RolTargeted |
Held KS, Virology 2004 Nov 24;329(2):251-60 |
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Ccr1tm1Gao | MGI:1931850 | Targeted | Null/knockout | MGI:3614443 | Coronavirus infectious disease | DOID:0080599 | cardiovascular system cellular hematopoietic system homeostasis/metabolism immune system respiratory system mortality/aging | MP:0005385 MP:0005384 MP:0005397 MP:0005376 MP:0005387 MP:0005388 MP:0010768 | Sheahan T, PLoS Pathog 2008 Dec;4(12):e1000240 | J:162707 | Pathology|SARS-CoV-MA_virus | Ccr1tm1GaoTargeted |
MGI:3614443 | cardiovascular system cellular hematopoietic system homeostasis/metabolism immune system respiratory system mortality/aging Coronavirus infectious disease |
Sheahan T, PLoS Pathog 2008 Dec;4(12):e1000240 |
Ccr2tm1Ifc | MGI:2158213 | Targeted | Null/knockout | MGI:3580323 | cellular hematopoietic system immune system nervous system skeleton neoplasm mortality/aging | MP:0005384 MP:0005397 MP:0005387 MP:0003631 MP:0005390 MP:0002006 MP:0010768 | Chen BP, J Immunol 2001 Oct 15;167(8):4585-92 | J:106738 | Mouse_Hepatitis_virus|Pathology | Ccr2tm1IfcTargeted |
MGI:3580323 | cellular hematopoietic system immune system nervous system skeleton neoplasm mortality/aging |
Chen BP, J Immunol 2001 Oct 15;167(8):4585-92 |
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Ccr2tm1Mae | MGI:2158345 | Targeted | Null/knockout | MGI:3841005 | age related macular degeneration Coronavirus infectious disease | DOID:10871 DOID:0080599 | behavior/neurological cardiovascular system hematopoietic system immune system nervous system pigmentation respiratory system vision/eye | MP:0005386 MP:0005385 MP:0005397 MP:0005387 MP:0003631 MP:0001186 MP:0005388 MP:0005391 | Held KS, Virology 2004 Nov 24;329(2):251-60 Glass WG, Virology 2001 Sep 15;288(1):8-17 Sheahan T, PLoS Pathog 2008 Dec;4(12):e1000240 | J:102446 J:102561 J:162707 | Infection|Mouse_Hepatitis_virus Mouse_Hepatitis_virus Pathology|SARS-CoV-MA_virus | Ccr2tm1MaeTargeted |
MGI:3841005 | behavior/neurological cardiovascular system hematopoietic system immune system nervous system pigmentation respiratory system vision/eye age related macular degeneration Coronavirus infectious disease |
Held KS, Virology 2004 Nov 24;329(2):251-60 Glass WG, Virology 2001 Sep 15;288(1):8-17 Sheahan T, PLoS Pathog 2008 Dec;4(12):e1000240 |
Ccr5tm1Kuz | MGI:1861911 | Targeted | Null/knockout | MGI:4418655 | Coronavirus infectious disease | DOID:0080599 | behavior/neurological cardiovascular system immune system nervous system respiratory system vision/eye mortality/aging | MP:0005386 MP:0005385 MP:0005387 MP:0003631 MP:0005388 MP:0005391 MP:0010768 | Sheahan T, PLoS Pathog 2008 Dec;4(12):e1000240 | J:162707 | Pathology|SARS-CoV-MA_virus | Ccr5tm1KuzTargeted |
MGI:4418655 | behavior/neurological cardiovascular system immune system nervous system respiratory system vision/eye mortality/aging Coronavirus infectious disease |
Sheahan T, PLoS Pathog 2008 Dec;4(12):e1000240 |
Ccr9tm1Lov | MGI:3654108 | Targeted | Null/knockout | Schafer A, bioRxiv 2021 May;(): Schafer A, mBio 2022 Aug 30;13(4):e0145422 | J:308730 J:327836 | Pathology|SARS-CoV-2-MA_virus|SARS-CoV-2_virus|SARS-CoV-MA_virus|SARS-CoV_virus SARS-CoV-2-MA_virus|SARS-CoV-MA_virus | Ccr9tm1LovTargeted |
Schafer A, bioRxiv 2021 May;(): Schafer A, mBio 2022 Aug 30;13(4):e0145422 |
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Cd19tm1(cre)Cgn | MGI:1931143 | Targeted | Recombinase | Cervantes-Barragan L, J Immunol 2009 Jan 15;182(2):1099-106 Atkinson JR, J Virol 2017 Dec 1;91(23): Kotagiri P, EBioMedicine 2022 Feb 18;77():103878 Luo Y, Signal Transduct Target Ther 2022 Jan 4;7(1):7 Sarden N, Sci Transl Med 2022 Dec 7;14(674):eabq6682 | J:143484 J:253411 J:322643 J:333746 J:336666 | Mouse_Hepatitis_virus SARS-CoV-2_virus SARS-CoV-2_virus|Vaccine Comorbidity|SARS-CoV-2_virus | Cd19tm1(cre)CgnTargeted |
Cervantes-Barragan L, J Immunol 2009 Jan 15;182(2):1099-106 Atkinson JR, J Virol 2017 Dec 1;91(23): Kotagiri P, EBioMedicine 2022 Feb 18;77():103878 Luo Y, Signal Transduct Target Ther 2022 Jan 4;7(1):7 Sarden N, Sci Transl Med 2022 Dec 7;14(674):eabq6682 |
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Cd1tm1Gru | MGI:1857482 | Targeted | Null/knockout | Johansen MD, Mucosal Immunol 2020 Aug 20;(): Glass WG, J Immunol 2004 Sep 15;173(6):4030-9 | J:295350 J:92752 | MERS-CoV-MA_virus|MERS-CoV_virus|SARS-CoV-2-MA_virus|SARS-CoV-2_virus|SARS-CoV-MA_virus|SARS-CoV_virus Infection|SARS-CoV_virus | Cd1tm1GruTargeted |
Johansen MD, Mucosal Immunol 2020 Aug 20;(): Glass WG, J Immunol 2004 Sep 15;173(6):4030-9 |
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Cd274tm1Lpc | MGI:3043876 | Targeted | Null/knockout | Phares TW, J Immunol 2009 May 1;182(9):5430-8 Phares TW, J Immunol 2010 Nov 1;185(9):5607-18 Phares TW, J Neuroinflammation 2012 Dec 14;9():269 | J:147948 J:165192 J:331800 | Mouse_Hepatitis_virus Gene|Mouse_Hepatitis_virus | Cd274tm1LpcTargeted |
Phares TW, J Immunol 2009 May 1;182(9):5430-8 Phares TW, J Immunol 2010 Nov 1;185(9):5607-18 Phares TW, J Neuroinflammation 2012 Dec 14;9():269 |
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Cd47tm1Fpl | MGI:1861955 | Targeted | Null/knockout | Wenzek C, iScience 2022 Dec 22;25(12):105540 | J:331693 | SARS-CoV-2_virus | Cd47tm1FplTargeted |
Wenzek C, iScience 2022 Dec 22;25(12):105540 |
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Cd4tm1Knw | MGI:1857143 | Targeted | Null/knockout | Yang J, Nature 2020 Jul 29;(): | J:292665 | SARS-CoV-2_virus|Vaccine | Cd4tm1KnwTargeted |
Yang J, Nature 2020 Jul 29;(): |
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Cd4tm1Litt | MGI:1857281 | Targeted | Null/knockout | Brentville VA, bioRxiv 2021 Jun;(): | J:308658 | SARS-CoV-2_virus|Vaccine | Cd4tm1LittTargeted |
Brentville VA, bioRxiv 2021 Jun;(): |
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Cd4tm1Mak | MGI:1857144 | Targeted | Null/knockout | Heemskerk MH, Eur J Immunol 1995 Apr;25(4):1109-12 Chakravarty D, J Virol 2020 Jul 1;94(14): | J:112983 J:290222 | Mouse_Hepatitis_virus Mouse_Hepatitis_virus|Pathology | Cd4tm1MakTargeted |
Heemskerk MH, Eur J Immunol 1995 Apr;25(4):1109-12 Chakravarty D, J Virol 2020 Jul 1;94(14): |
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Cd79atm1(cre)Reth | MGI:3687451 | Targeted | Null/knockout|Recombinase | Kotagiri P, EBioMedicine 2022 Feb 18;77():103878 | J:322643 | SARS-CoV-2_virus | Cd79atm1(cre)RethTargeted |
Kotagiri P, EBioMedicine 2022 Feb 18;77():103878 |
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Cd8atm1Mak | MGI:1857149 | Targeted | Null/knockout | Yang J, Nature 2020 Jul 29;(): | J:292665 | SARS-CoV-2_virus|Vaccine | Cd8atm1MakTargeted |
Yang J, Nature 2020 Jul 29;(): |
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Ceacam1Hv2-r | MGI:3053078 | Spontaneous | MGI:3719417 | immune system | MP:0005387 | Peng G, J Biol Chem 2017 Feb 10;292(6):2174-2181 Yokomori K, J Virol 1992 Dec;66(12):6931-8 Dveksler GS, J Virol 1991 Dec;65(12):6881-91 Dveksler GS, J Virol 1993 Jan;67(1):1-8 | J:240703 J:3241 J:701 J:92495 | Mouse_Hepatitis_virus Infection|Mouse_Hepatitis_virus | Ceacam1Hv2-rSpontaneous |
MGI:3719417 | immune system |
Peng G, J Biol Chem 2017 Feb 10;292(6):2174-2181 Yokomori K, J Virol 1992 Dec;66(12):6931-8 Dveksler GS, J Virol 1991 Dec;65(12):6881-91 Dveksler GS, J Virol 1993 Jan;67(1):1-8 |
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Ceacam1Hv2-s | MGI:3027072 | Spontaneous | MGI:3719418 | immune system | MP:0005387 | Peng G, J Biol Chem 2017 Feb 10;292(6):2174-2181 Yokomori K, J Virol 1992 Dec;66(12):6931-8 Dveksler GS, J Virol 1991 Dec;65(12):6881-91 Dveksler GS, J Virol 1993 Jan;67(1):1-8 | J:240703 J:3241 J:701 J:92495 | Mouse_Hepatitis_virus Infection|Mouse_Hepatitis_virus | Ceacam1Hv2-sSpontaneous |
MGI:3719418 | immune system |
Peng G, J Biol Chem 2017 Feb 10;292(6):2174-2181 Yokomori K, J Virol 1992 Dec;66(12):6931-8 Dveksler GS, J Virol 1991 Dec;65(12):6881-91 Dveksler GS, J Virol 1993 Jan;67(1):1-8 |
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Ceacam1tm1.1Fta | MGI:5496530 | Targeted | Inserted expressed sequence | MGI:5496535 | immune system mortality/aging | MP:0005387 MP:0010768 | Hirai A, J Virol 2010 Jul;84(13):6654-66 | J:198335 | Infection|Mouse_Hepatitis_virus | Ceacam1tm1.1FtaTargeted |
MGI:5496535 | immune system mortality/aging |
Hirai A, J Virol 2010 Jul;84(13):6654-66 |
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Ceacam1tm1Bcn | MGI:2180785 | Targeted | Null/knockout | MGI:2656211 | immune system mortality/aging | MP:0005387 MP:0010768 | Blau DM, J Virol 2001 Sep;75(17):8173-86 Hemmila E, J Virol 2004 Sep;78(18):10156-65 | J:70815 J:92376 | Infection|Mouse_Hepatitis_virus | Ceacam1tm1BcnTargeted |
MGI:2656211 | immune system mortality/aging |
Blau DM, J Virol 2001 Sep;75(17):8173-86 Hemmila E, J Virol 2004 Sep;78(18):10156-65 |
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Ceacam1tm2Bcn | MGI:3053071 | Targeted | Null/knockout | MGI:3053437 | digestive/alimentary system homeostasis/metabolism immune system neoplasm | MP:0005381 MP:0005376 MP:0005387 MP:0002006 | Miura TA, J Virol 2008 Jan;82(2):755-63 Hemmila E, J Virol 2004 Sep;78(18):10156-65 | J:130131 J:92376 | Mouse_Hepatitis_virus Infection|Mouse_Hepatitis_virus | Ceacam1tm2BcnTargeted |
MGI:3053437 | digestive/alimentary system homeostasis/metabolism immune system neoplasm |
Miura TA, J Virol 2008 Jan;82(2):755-63 Hemmila E, J Virol 2004 Sep;78(18):10156-65 |
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Ces1ctm1.1Loc | MGI:4938302 | Targeted | Null/knockout | Sheahan TP, Sci Transl Med 2017 Jun 28;9(396): Sheahan TP, Nat Commun 2020 Jan 10;11(1):222 Pruijssers AJ, Cell Rep 2020 Jul 21;32(3):107940 Martinez DR, bioRxiv 2021 Jan;(): Zhu C, Nat Commun 2022 Aug 3;13(1):4503 | J:286362 J:286402 J:298752 J:302135 J:335969 | MERS-CoV_virus|SARS-CoV_virus|Treatment MERS-CoV_virus|Treatment SARS-CoV-2-MA_virus|SARS-CoV-2_virus|Treatment SARS-CoV-2_virus|Treatment | Ces1ctm1.1LocTargeted |
Sheahan TP, Sci Transl Med 2017 Jun 28;9(396): Sheahan TP, Nat Commun 2020 Jan 10;11(1):222 Pruijssers AJ, Cell Rep 2020 Jul 21;32(3):107940 Martinez DR, bioRxiv 2021 Jan;(): Zhu C, Nat Commun 2022 Aug 3;13(1):4503 |
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Cfbtm1Hrc | MGI:1861129 | Targeted | Null/knockout | MGI:3771614 | immune system | MP:0005387 | Gralinski LE, mBio 2018 Oct 9;9(5): | J:286325 | Pathology|SARS-CoV-MA_virus | Cfbtm1HrcTargeted |
MGI:3771614 | immune system |
Gralinski LE, mBio 2018 Oct 9;9(5): |
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Ch25htm1Rus | MGI:4947407 | Targeted | Null/knockout | Fessler MB, Am J Respir Cell Mol Biol 2023 Dec;69(6):638-648 | J:343658 | SARS-CoV-2_virus | Ch25htm1RusTargeted |
Fessler MB, Am J Respir Cell Mol Biol 2023 Dec;69(6):638-648 |
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Ciitatm1Ccum | MGI:1857456 | Targeted | Null/knockout | Chen JS, bioRxiv 2021 Jun;(): | J:308655 | SARS-CoV-2_virus|VOC_B.1.351_Beta | Ciitatm1CcumTargeted |
Chen JS, bioRxiv 2021 Jun;(): |
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Cmpk2tm1c(KOMP)Wtsi | MGI:6753388 | Targeted | Conditional ready | Xian H, Immunity 2021 Jul 13;54(7):1463-1477.e11 | J:308159 | Pathology|SARS-CoV-2_virus|Treatment | Cmpk2tm1c(KOMP)WtsiTargeted |
Xian H, Immunity 2021 Jul 13;54(7):1463-1477.e11 |
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Col1a1tm1(tetO-Cpt1a,-GFP)Slms | MGI:7564295 | Targeted | Inducible|Inserted expressed sequence | Miguel V, Redox Biol 2023 Dec;68():102957 | J:343262 | Treatment | Col1a1tm1(tetO-Cpt1a,-GFP)SlmsTargeted |
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Commd10Tg(Vav1-icre)A2Kio | MGI:2449949 | Transgenic | Null/knockout|Recombinase | Pfaender S, Nat Microbiol 2020 Jul 23;(): | J:291868 | Gene|HCoV-229E_virus|HCoV-OC43_virus|MERS-CoV_virus|Mouse_Hepatitis_virus|SARS-CoV-2_virus|SARS-CoV_virus | Commd10Tg(Vav1-icre)A2KioTransgenic |
Pfaender S, Nat Microbiol 2020 Jul 23;(): |
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Csf1tm1.1(CSF1)Flv | MGI:5296679 | Targeted | Humanized sequence|Inserted expressed sequence | Sefik E, bioRxiv 2021;(): | J:311907 | SARS-CoV-2_virus | Csf1tm1.1(CSF1)FlvTargeted |
Sefik E, bioRxiv 2021;(): |
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Csf2/Il3tm1.1(CSF2,IL3)Flv | MGI:4887881 | Targeted | Humanized sequence|Inserted expressed sequence | Sefik E, bioRxiv 2021;(): | J:311907 | SARS-CoV-2_virus | Csf2/Il3tm1.1(CSF2,IL3)FlvTargeted |
Sefik E, bioRxiv 2021;(): |
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Csf2tm1Mlg | MGI:1930996 | Targeted | Null/knockout | Ngo VL, Cell Host Microbe 2024 Jan 23;(): | J:345954 | Infection|MERS-CoV-MA_virus | Csf2tm1MlgTargeted |
Ngo VL, Cell Host Microbe 2024 Jan 23;(): |
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Ctnnb1tm1Knw | MGI:3767601 | Targeted | Conditional ready | Harb H, Immunity 2021 Apr 22;(): | J:347529 | Infection | Ctnnb1tm1KnwTargeted |
Harb H, Immunity 2021 Apr 22;(): |
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Cx3cr1tm1Litt | MGI:2670351 | Targeted | Null/knockout|Reporter | Wheeler DL, J Clin Invest 2018 Mar 1;128(3):931-943 | J:291614 | Mouse_Hepatitis_virus | Cx3cr1tm1LittTargeted |
Wheeler DL, J Clin Invest 2018 Mar 1;128(3):931-943 |
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Cx3cr1tm2.1(cre/ERT2)Litt | MGI:5450813 | Targeted | Inducible|Recombinase|Reporter | Verma AK, mBio 2021 Oct 26;12(5):e0196921 | J:313438 | Mouse_Hepatitis_virus | Cx3cr1tm2.1(cre/ERT2)LittTargeted |
Verma AK, mBio 2021 Oct 26;12(5):e0196921 |
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Cxcl10tm1Adl | MGI:2180678 | Targeted | Null/knockout | Stiles LN, J Immunol 2006 Dec 15;177(12):8372-80 | J:140673 | Mouse_Hepatitis_virus | Cxcl10tm1AdlTargeted |
Stiles LN, J Immunol 2006 Dec 15;177(12):8372-80 |
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Cxcl13tm1Cys | MGI:2384500 | Targeted | Null/knockout|Reporter | Phares TW, Brain Behav Immun 2016 May;54():128-139 | J:316468 | Mouse_Hepatitis_virus | Cxcl13tm1CysTargeted |
Phares TW, Brain Behav Immun 2016 May;54():128-139 |
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Cxcl5tm1Gscw | MGI:4819800 | Targeted | Null/knockout | Liang Y, Zool Res 2020 Oct 12;():1-29 | J:296738 | Infection|Pathology|SARS-CoV-2_virus | Cxcl5tm1GscwTargeted |
Liang Y, Zool Res 2020 Oct 12;():1-29 |
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Cxcr3tm1Dgen | MGI:3604545 | Targeted | Null/knockout|Reporter | McDermott JE, BMC Syst Biol 2016 Sep 23;10(1):93 | J:288523 | Pathology|SARS-CoV-MA_virus | Cxcr3tm1DgenTargeted |
McDermott JE, BMC Syst Biol 2016 Sep 23;10(1):93 |
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Cxcr6tm1Litt | MGI:3613526 | Targeted | Null/knockout|Reporter | Schafer A, mBio 2022 Aug 30;13(4):e0145422 | J:327836 | SARS-CoV-2-MA_virus|SARS-CoV-MA_virus | Cxcr6tm1LittTargeted |
Schafer A, mBio 2022 Aug 30;13(4):e0145422 |
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Dpp4em1Rba | MGI:6400423 | Endonuclease-mediated | Humanized sequence | MGI:6400425 | Middle East respiratory syndrome | DOID:0080642 | cardiovascular system growth/size/body hematopoietic system homeostasis/metabolism immune system respiratory system mortality/aging | MP:0005385 MP:0005378 MP:0005397 MP:0005376 MP:0005387 MP:0005388 MP:0010768 | Leist SR, PLoS One 2019;14(7):e0220126 Cockrell AS, Nat Microbiol 2016 Nov 28;2():16226 Leist SR, Methods Mol Biol 2020;2099():137-159 Sheahan TP, Sci Transl Med 2020 Apr 29;12(541): Sheahan TP, Nat Commun 2020 Jan 10;11(1):222 Menachery VD, mBio 2017 Aug 22;8(4): Singh A, Virol Sin 2020 Jun;35(3):290-304 Johansen MD, Mucosal Immunol 2020 Aug 20;(): Gutierrez-Alvarez J, J Virol 2021 Jan 13;95(3): | J:279723 J:279834 J:285962 J:286320 J:286402 J:287147 J:295349 J:295350 J:300138 | MERS-CoV_virus|Pathology MERS-CoV_virus MERS-CoV_virus|SARS-CoV-2_virus|SARS-CoV-MA_virus|SARS-CoV_virus|Treatment MERS-CoV_virus|Treatment Infection|MERS-CoV_virus MERS-CoV-MA_virus|MERS-CoV_virus|SARS-CoV-2-MA_virus|SARS-CoV-2_virus|SARS-CoV_virus MERS-CoV-MA_virus|MERS-CoV_virus|SARS-CoV-2-MA_virus|SARS-CoV-2_virus|SARS-CoV-MA_virus|SARS-CoV_virus | Dpp4em1RbaEndonuclease-mediated |
MGI:6400425 | cardiovascular system growth/size/body hematopoietic system homeostasis/metabolism immune system respiratory system mortality/aging Middle East respiratory syndrome |
Leist SR, PLoS One 2019;14(7):e0220126 Cockrell AS, Nat Microbiol 2016 Nov 28;2():16226 Leist SR, Methods Mol Biol 2020;2099():137-159 Sheahan TP, Sci Transl Med 2020 Apr 29;12(541): Sheahan TP, Nat Commun 2020 Jan 10;11(1):222 Menachery VD, mBio 2017 Aug 22;8(4): Singh A, Virol Sin 2020 Jun;35(3):290-304 Johansen MD, Mucosal Immunol 2020 Aug 20;(): Gutierrez-Alvarez J, J Virol 2021 Jan 13;95(3): |
Dpp4em2(DPP4)Smoc | MGI:6415291 | Endonuclease-mediated | Inserted expressed sequence | Xia LY, Nat Commun 2024 Feb 5;15(1):1048 | J:353426 | Infection | Dpp4em2(DPP4)SmocEndonuclease-mediated |
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Dpp4tm1.1(DPP4)Pbmj | MGI:6400999 | Targeted | Humanized sequence|Inserted expressed sequence | MGI:6401000 | Middle East respiratory syndrome | DOID:0080642 | cardiovascular system homeostasis/metabolism immune system respiratory system mortality/aging | MP:0005385 MP:0005376 MP:0005387 MP:0005388 MP:0010768 | Li K, Proc Natl Acad Sci U S A 2017 Apr 11;114(15):E3119-E3128 Leist SR, Methods Mol Biol 2020;2099():137-159 Jia W, Emerg Microbes Infect 2019;8(1):760-772 Li K, mBio 2020 Apr 7;11(2): Channappanavar R, J Clin Invest 2019 Jul 29;130():3625-3639 Singh A, Virol Sin 2020 Jun;35(3):290-304 Johansen MD, Mucosal Immunol 2020 Aug 20;(): Yuan L, Emerg Microbes Infect 2020 Dec;9(1):949-961 Gutierrez-Alvarez J, J Virol 2021 Jan 13;95(3): Zheng J, J Clin Invest 2021 Jun 1;131(11): Gutierrez-Alvarez J, Proc Natl Acad Sci U S A 2021 Oct 26;118(43):e2111075118 Wong L-YR, mBio 2023 Oct 26;14(6):e0247623 | J:242025 J:285962 J:286329 J:287921 J:288107 J:295349 J:295350 J:300104 J:300138 J:311966 J:315826 J:343780 | Infection|MERS-CoV-MA_virus|Pathology MERS-CoV_virus MERS-CoV-MA_virus|MERS-CoV_virus|Vaccine Infection|MERS-CoV-MA_virus|Treatment MERS-CoV-MA_virus|MERS-CoV_virus|SARS-CoV-2-MA_virus|SARS-CoV-2_virus|SARS-CoV_virus MERS-CoV-MA_virus|MERS-CoV_virus|SARS-CoV-2-MA_virus|SARS-CoV-2_virus|SARS-CoV-MA_virus|SARS-CoV_virus MERS-CoV_virus|SARS-CoV-2_virus|SARS-CoV_virus Comorbidity|MERS-CoV_virus MERS-CoV_virus|Vaccine MERS-CoV-MA_virus|Pathology|SARS-CoV-2_virus | Dpp4tm1.1(DPP4)PbmjTargeted |
MGI:6401000 | cardiovascular system homeostasis/metabolism immune system respiratory system mortality/aging Middle East respiratory syndrome |
Li K, Proc Natl Acad Sci U S A 2017 Apr 11;114(15):E3119-E3128 Leist SR, Methods Mol Biol 2020;2099():137-159 Jia W, Emerg Microbes Infect 2019;8(1):760-772 Li K, mBio 2020 Apr 7;11(2): Channappanavar R, J Clin Invest 2019 Jul 29;130():3625-3639 Singh A, Virol Sin 2020 Jun;35(3):290-304 Johansen MD, Mucosal Immunol 2020 Aug 20;(): Yuan L, Emerg Microbes Infect 2020 Dec;9(1):949-961 Gutierrez-Alvarez J, J Virol 2021 Jan 13;95(3): Zheng J, J Clin Invest 2021 Jun 1;131(11): Gutierrez-Alvarez J, Proc Natl Acad Sci U S A 2021 Oct 26;118(43):e2111075118 Wong L-YR, mBio 2023 Oct 26;14(6):e0247623 |
Dpp4tm1(DPP4)Vlcg | MGI:5788094 | Targeted | Inserted expressed sequence|Null/knockout | MGI:6400455 MGI:6435210 | Middle East respiratory syndrome | DOID:0080642 | immune system respiratory system hematopoietic system homeostasis/metabolism | MP:0005387 MP:0005388 MP:0005397 MP:0005376 | Pascal KE, Proc Natl Acad Sci U S A 2015 Jul 14;112(28):8738-43 Coleman CM, J Virol 2017 Jan 01;91(1): Leist SR, Methods Mol Biol 2020;2099():137-159 Kulcsar KA, JCI Insight 2019 Oct 17;4(20): Singh A, Virol Sin 2020 Jun;35(3):290-304 | J:223728 J:238079 J:285962 J:286238 J:295349 | Infection|MERS-CoV_virus|Treatment MERS-CoV_virus|Pathology MERS-CoV_virus Comorbidity|MERS-CoV_virus|Pathology MERS-CoV-MA_virus|MERS-CoV_virus|SARS-CoV-2-MA_virus|SARS-CoV-2_virus|SARS-CoV_virus | Dpp4tm1(DPP4)VlcgTargeted |
MGI:6400455 MGI:6435210 | immune system respiratory system Middle East respiratory syndrome hematopoietic system homeostasis/metabolism |
Pascal KE, Proc Natl Acad Sci U S A 2015 Jul 14;112(28):8738-43 Coleman CM, J Virol 2017 Jan 01;91(1): Leist SR, Methods Mol Biol 2020;2099():137-159 Kulcsar KA, JCI Insight 2019 Oct 17;4(20): Singh A, Virol Sin 2020 Jun;35(3):290-304 |
Dyrk1atm1Jdc | MGI:5648391 | Targeted | Conditional ready|No functional change | Strine MS, PLoS Biol 2023 Jun;21(6):e3002097 | J:341033 | Gene|MERS-CoV_virus|SARS-CoV-2_virus|SARS-CoV_virus | Dyrk1atm1JdcTargeted |
Strine MS, PLoS Biol 2023 Jun;21(6):e3002097 |
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Ebi3Gt716Lex | MGI:3793965 | Gene trapped | Null/knockout|Reporter | MGI:6442003 | hematopoietic system immune system nervous system mortality/aging | MP:0005397 MP:0005387 MP:0003631 MP:0010768 | Tirotta E, J Neuroimmunol 2013 Jan 15;254(1-2):110-6 | J:286951 | Infection|Mouse_Hepatitis_virus | Ebi3Gt716LexGene trapped |
MGI:6442003 | hematopoietic system immune system nervous system mortality/aging |
Tirotta E, J Neuroimmunol 2013 Jan 15;254(1-2):110-6 |
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Edil3Tg(Sox2-cre)1Amc | MGI:2656539 | Transgenic | Null/knockout|Recombinase | Tang AT, bioRxiv 2021 Dec;(): Tang AT, PLoS Biol 2023 Feb;21(2):e3001989 | J:315719 J:337814 | Pathology|SARS-CoV-2_virus Pathology|SARS-CoV-2_virus|VOC_B.1.1.529_Omicron | Edil3Tg(Sox2-cre)1AmcTransgenic |
Tang AT, bioRxiv 2021 Dec;(): Tang AT, PLoS Biol 2023 Feb;21(2):e3001989 |
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EgfrMhdadsk5 | MGI:2682255 | Chemically induced (ENU) | Venkataraman T, J Virol 2017 Jun 15;91(12): | J:243599 | Pathology|SARS-CoV-MA_virus | EgfrMhdadsk5Chemically induced (ENU) |
Venkataraman T, J Virol 2017 Jun 15;91(12): |
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Eif2ak2tm1Cwe | MGI:2182566 | Targeted | Null/knockout | Kindler E, PLoS Pathog 2017 Feb;13(2):e1006195 | J:291588 | HCoV-229E_virus|Mouse_Hepatitis_virus | Eif2ak2tm1CweTargeted |
Kindler E, PLoS Pathog 2017 Feb;13(2):e1006195 |
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Elanetm1Sds | MGI:2182771 | Targeted | Null/knockout | Kim E, Proc Natl Acad Sci U S A 2021 Aug 24;118(34):e2102435118 | J:313327 | SARS-CoV-2_virus|Vaccine | Elanetm1SdsTargeted |
Kim E, Proc Natl Acad Sci U S A 2021 Aug 24;118(34):e2102435118 |
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Eportm1.1(EGFP/icre)Uk | MGI:3052727 | Targeted | Null/knockout|Recombinase|Reporter | Lam LKM, Sci Transl Med 2021 Oct 20;13(616):eabj1008 | J:325468 | SARS-CoV-2_virus | Eportm1.1(EGFP/icre)UkTargeted |
Lam LKM, Sci Transl Med 2021 Oct 20;13(616):eabj1008 |
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Faddtm1Mak | MGI:2159360 | Targeted | Null/knockout | Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 | J:296686 | Pathology|SARS-CoV-2_virus|Treatment | Faddtm1MakTargeted |
Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 |
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Faddtm1Mpa | MGI:3700154 | Targeted | Conditional ready|No functional change | Wenzel J, Nat Neurosci 2021 Nov;24(11):1522-1533 | J:323957 | Pathology|SARS-CoV-2_virus|VOC_B.1.351_Beta | Faddtm1MpaTargeted |
Wenzel J, Nat Neurosci 2021 Nov;24(11):1522-1533 |
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Fcer1gtm1Rav | MGI:1857165 | Targeted | Null/knockout | Adams LE, Cell Rep 2023 Mar 30;42(4):112326 | J:349062 | SARS-CoV-2-MA_virus|Vaccine | Fcer1gtm1RavTargeted |
Adams LE, Cell Rep 2023 Mar 30;42(4):112326 |
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Fcgrttm1Dcr | MGI:3511510 | Targeted | Null/knockout | Halwe S, bioRxiv 2021 Jun;(): | J:308648 | SARS-CoV-2_virus|Treatment|VOC_B.1.1.7_Alpha|VOC_B.1.351_Beta | Fcgrttm1DcrTargeted |
Halwe S, bioRxiv 2021 Jun;(): |
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Fgatm1Jld | MGI:2152976 | Targeted | Null/knockout | Ryu JK, bioRxiv 2021;(): | J:311923 | SARS-CoV-2_virus|Treatment | Fgatm1JldTargeted |
Ryu JK, bioRxiv 2021;(): |
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Fggtm2Jld | MGI:3046446 | Targeted | Ryu JK, bioRxiv 2021;(): | J:311923 | SARS-CoV-2_virus|Treatment | Fggtm2JldTargeted |
Ryu JK, bioRxiv 2021;(): |
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Fgl2tm1Pam | MGI:3582343 | Targeted | Null/knockout|Reporter | MGI:3583696 MGI:3583697 | autoimmune glomerulonephritis | DOID:0040094 | cardiovascular system homeostasis/metabolism immune system mortality/aging cellular growth/size/body hematopoietic system renal/urinary system | MP:0005385 MP:0005376 MP:0005387 MP:0010768 MP:0005384 MP:0005378 MP:0005397 MP:0005367 | Marsden PA, J Clin Invest 2003 Jul;112(1):58-66 | J:99453 | Mouse_Hepatitis_virus | Fgl2tm1PamTargeted |
MGI:3583696 MGI:3583697 | cardiovascular system homeostasis/metabolism immune system mortality/aging cellular growth/size/body hematopoietic system renal/urinary system autoimmune glomerulonephritis |
Marsden PA, J Clin Invest 2003 Jul;112(1):58-66 |
Foxg1tm1.1(cre)Ddmo | MGI:5818697 | Targeted | Recombinase | Tang AT, bioRxiv 2021 Dec;(): Tang AT, PLoS Biol 2023 Feb;21(2):e3001989 | J:315719 J:337814 | Pathology|SARS-CoV-2_virus Pathology|SARS-CoV-2_virus|VOC_B.1.1.529_Omicron | Foxg1tm1.1(cre)DdmoTargeted |
Tang AT, bioRxiv 2021 Dec;(): Tang AT, PLoS Biol 2023 Feb;21(2):e3001989 |
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Foxp3tm2Ayr | MGI:3574964 | Targeted | No functional change|Reporter | Zhao J, J Exp Med 2011 Aug 1;208(8):1571-7 | J:177608 | Mouse_Hepatitis_virus | Foxp3tm2AyrTargeted |
Zhao J, J Exp Med 2011 Aug 1;208(8):1571-7 |
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Foxp3tm2Tch | MGI:3699400 | Targeted | Reporter | Zhao J, PLoS Pathog 2014 Aug;10(8):e1004279 Sariol A, J Immunol 2022 Apr 15;208(8):1989-1997 | J:247329 J:324704 | Mouse_Hepatitis_virus Infection|Mouse_Hepatitis_virus | Foxp3tm2TchTargeted |
Zhao J, PLoS Pathog 2014 Aug;10(8):e1004279 Sariol A, J Immunol 2022 Apr 15;208(8):1989-1997 |
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Foxp3tm3(HBEGF/GFP)Ayr | MGI:3698131 | Targeted | Inserted expressed sequence|Reporter | Uraki R, PLoS Pathog 2021 Dec;17(12):e1010085 | J:327784 | SARS-CoV-2_virus | Foxp3tm3(HBEGF/GFP)AyrTargeted |
Uraki R, PLoS Pathog 2021 Dec;17(12):e1010085 |
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Foxp3tm4(YFP/icre)Ayr | MGI:3790499 | Targeted | Recombinase | Harb H, Immunity 2021 Apr 22;(): | J:347529 | Infection | Foxp3tm4(YFP/icre)AyrTargeted |
Harb H, Immunity 2021 Apr 22;(): |
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Foxp3tm9(EGFP/cre/ERT2)Ayr | MGI:4950935 | Targeted | Inducible|Recombinase|Reporter | Sariol A, J Immunol 2022 Apr 15;208(8):1989-1997 | J:324704 | Infection|Mouse_Hepatitis_virus | Foxp3tm9(EGFP/cre/ERT2)AyrTargeted |
Sariol A, J Immunol 2022 Apr 15;208(8):1989-1997 |
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G3bp1em1Gpt | MGI:7299354 | Endonuclease-mediated | Conditional ready|No functional change | Liu H, J Virol 2022 Jun 22;96(12):e0041222 | J:342298 | Gene|SARS-CoV-2-MA_virus|SARS-CoV-2_virus | G3bp1em1GptEndonuclease-mediated |
Liu H, J Virol 2022 Jun 22;96(12):e0041222 |
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Gbp2tm1.1Kpf | MGI:5475104 | Targeted | Null/knockout|Reporter | Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 | J:296686 | Pathology|SARS-CoV-2_virus|Treatment | Gbp2tm1.1KpfTargeted |
Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 |
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Gpr183tm1.1(KOMP)Vlcg | MGI:5617257 | Targeted | Null/knockout|Reporter | Fessler MB, Am J Respir Cell Mol Biol 2023 Dec;69(6):638-648 | J:343658 | SARS-CoV-2_virus | Gpr183tm1.1(KOMP)VlcgTargeted |
Fessler MB, Am J Respir Cell Mol Biol 2023 Dec;69(6):638-648 |
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Gsdmdem1Tdk | MGI:6342025 | Endonuclease-mediated | Null/knockout | Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 Zheng M, J Biol Chem 2020 Oct 9;295(41):14040-14052 Eltobgy MM, Proc Natl Acad Sci U S A 2022 May 24;119(21):e2202012119 | J:296686 J:298138 J:331823 | Pathology|SARS-CoV-2_virus|Treatment Mouse_Hepatitis_virus Gene|SARS-CoV-2-MA_virus|SARS-CoV-2_virus | Gsdmdem1TdkEndonuclease-mediated |
Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 Zheng M, J Biol Chem 2020 Oct 9;295(41):14040-14052 Eltobgy MM, Proc Natl Acad Sci U S A 2022 May 24;119(21):e2202012119 |
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Gsdmdem4Fcw | MGI:6196334 | Endonuclease-mediated | Null/knockout | Wu J, Immunity 2021 Nov 9;54(11):2632-2649.e6 | J:323769 | Gene|Pathology | Gsdmdem4FcwEndonuclease-mediated |
Wu J, Immunity 2021 Nov 9;54(11):2632-2649.e6 |
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Gsdmetm1a(KOMP)Wtsi | MGI:4363231 | Targeted | Conditional ready|Null/knockout|Reporter | Zheng M, J Biol Chem 2020 Oct 9;295(41):14040-14052 | J:298138 | Mouse_Hepatitis_virus | Gsdmetm1a(KOMP)WtsiTargeted |
Zheng M, J Biol Chem 2020 Oct 9;295(41):14040-14052 |
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Gt(ROSA)26Sorem1(CAG-ACE2)Mlkn | MGI:6842323 | Endonuclease-mediated | Conditional ready|Humanized sequence|Inserted expressed sequence | Tang AT, bioRxiv 2021 Dec;(): Tang AT, PLoS Biol 2023 Feb;21(2):e3001989 Gao S, Front Cardiovasc Med 2023;10():1266276 | J:315719 J:337814 J:346048 | Pathology|SARS-CoV-2_virus Pathology|SARS-CoV-2_virus|VOC_B.1.1.529_Omicron Infection|SARS-CoV-2_virus | Gt(ROSA)26Sorem1(CAG-ACE2)MlknEndonuclease-mediated |
Tang AT, bioRxiv 2021 Dec;(): Tang AT, PLoS Biol 2023 Feb;21(2):e3001989 Gao S, Front Cardiovasc Med 2023;10():1266276 |
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Gt(ROSA)26Sorem1(CAG-N,CAG-ACE2)Liwe | MGI:7570165 | Endonuclease-mediated | Conditional ready|Epitope tag|Humanized sequence|Inserted expressed sequence | Yang B, Cell Discov 2023 Apr 20;9(1):43 | J:338826 | Infection|Pathology|SARS-CoV-2_virus | Gt(ROSA)26Sorem1(CAG-N,CAG-ACE2)LiweEndonuclease-mediated |
Yang B, Cell Discov 2023 Apr 20;9(1):43 |
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Gt(ROSA)26Sorem1(DPP4)Yowa | MGI:6403442 | Endonuclease-mediated | Humanized sequence|Inserted expressed sequence|Reporter | MGI:6403447 | Middle East respiratory syndrome | DOID:0080642 | immune system nervous system | MP:0005387 MP:0003631 | Fan C, Viruses 2018 Aug 23;10(9): Zhou H, Nat Commun 2019 Jul 11;10(1):3068 Singh A, Virol Sin 2020 Jun;35(3):290-304 | J:279060 J:279324 J:295349 | Infection|MERS-CoV_virus|Pathology|Treatment MERS-CoV_virus MERS-CoV-MA_virus|MERS-CoV_virus|SARS-CoV-2-MA_virus|SARS-CoV-2_virus|SARS-CoV_virus | Gt(ROSA)26Sorem1(DPP4)YowaEndonuclease-mediated |
MGI:6403447 | immune system nervous system Middle East respiratory syndrome |
Fan C, Viruses 2018 Aug 23;10(9): Zhou H, Nat Commun 2019 Jul 11;10(1):3068 Singh A, Virol Sin 2020 Jun;35(3):290-304 |
Gt(ROSA)26Sortm1.1(Ace2)Spo | MGI:6406372 | Targeted | Inserted expressed sequence | Jia H, Nat Commun 2020 Oct 14;11(1):5165 | J:296535 | SARS-CoV-2_virus | Gt(ROSA)26Sortm1.1(Ace2)SpoTargeted |
Jia H, Nat Commun 2020 Oct 14;11(1):5165 |
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Gt(ROSA)26Sortm14(CAG-tdTomato)Hze | MGI:3809524 | Targeted | Conditional ready|Reporter | Pan R, Proc Natl Acad Sci U S A 2020 Jul 7;117(27):15902-15910 Tang AT, bioRxiv 2021 Dec;(): Nakandakari-Higa S, Front Immunol 2022;13():1007080 Tang AT, PLoS Biol 2023 Feb;21(2):e3001989 | J:291543 J:315719 J:335150 J:337814 | Infection|Mouse_Hepatitis_virus Pathology|SARS-CoV-2_virus Infection|SARS-CoV-2_virus|VOC_B.1.1.529_Omicron Pathology|SARS-CoV-2_virus|VOC_B.1.1.529_Omicron | Gt(ROSA)26Sortm14(CAG-tdTomato)HzeTargeted |
Pan R, Proc Natl Acad Sci U S A 2020 Jul 7;117(27):15902-15910 Tang AT, bioRxiv 2021 Dec;(): Nakandakari-Higa S, Front Immunol 2022;13():1007080 Tang AT, PLoS Biol 2023 Feb;21(2):e3001989 |
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Gt(ROSA)26Sortm1(cre/ERT)Nat | MGI:2669525 | Targeted | Inducible|Recombinase | Sepe S, EMBO Rep 2022 Feb 3;23(2):e53658 | J:326929 | Gene | Gt(ROSA)26Sortm1(cre/ERT)NatTargeted |
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Gt(ROSA)26Sortm1(EYFP)Cos | MGI:2449038 | Targeted | Conditional ready|Reporter | Gregoire C, bioRxiv 2021 Dec;(): | J:316768 | SARS-CoV-2_virus | Gt(ROSA)26Sortm1(EYFP)CosTargeted |
Gregoire C, bioRxiv 2021 Dec;(): |
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Gt(ROSA)26Sortm1(FLP1)Dym | MGI:2429412 | Targeted | Recombinase | Pfaender S, Nat Microbiol 2020 Jul 23;(): | J:291868 | Gene|HCoV-229E_virus|HCoV-OC43_virus|MERS-CoV_virus|Mouse_Hepatitis_virus|SARS-CoV-2_virus|SARS-CoV_virus | Gt(ROSA)26Sortm1(FLP1)DymTargeted |
Pfaender S, Nat Microbiol 2020 Jul 23;(): |
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Gt(ROSA)26Sortm1(gp80,EGFP)Eces | MGI:5004724 | Targeted | Conditional ready|Inserted expressed sequence|Reporter | Musiu C, Cell Death Differ 2021 Sep 13;(): | J:313338 | Pathology|SARS-CoV-2_virus | Gt(ROSA)26Sortm1(gp80,EGFP)EcesTargeted |
Musiu C, Cell Death Differ 2021 Sep 13;(): |
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Gt(ROSA)26Sortm1(rtTA,EGFP)Nagy | MGI:3583817 | Targeted | Conditional ready|Reporter|Transactivator | Wu J, Immunity 2021 Nov 9;54(11):2632-2649.e6 | J:323769 | Gene|Pathology | Gt(ROSA)26Sortm1(rtTA,EGFP)NagyTargeted |
Wu J, Immunity 2021 Nov 9;54(11):2632-2649.e6 |
|||||||
Gt(ROSA)26Sortm9(CAG-tdTomato)Hze | MGI:3809523 | Targeted | Conditional ready|Reporter | Sariol A, J Immunol 2022 Apr 15;208(8):1989-1997 | J:324704 | Infection|Mouse_Hepatitis_virus | Gt(ROSA)26Sortm9(CAG-tdTomato)HzeTargeted |
Sariol A, J Immunol 2022 Apr 15;208(8):1989-1997 |
|||||||
H2-Ab1b-tm1Doi | MGI:1927483 | Targeted | Null/knockout | Brentville VA, bioRxiv 2021 Jun;(): Houtman JJ, J Neurovirol 1996 APR;2(2):101-110 | J:308658 J:33974 | SARS-CoV-2_virus|Vaccine Mouse_Hepatitis_virus | H2-Ab1b-tm1DoiTargeted |
Brentville VA, bioRxiv 2021 Jun;(): Houtman JJ, J Neurovirol 1996 APR;2(2):101-110 |
|||||||
H2b | MGI:3579319 | Not Applicable | Bergmann CC, J Immunol 2001 Aug 1;167(3):1575-83 | J:120484 | Mouse_Hepatitis_virus | H2bNot Applicable |
Bergmann CC, J Immunol 2001 Aug 1;167(3):1575-83 |
||||||||
H2-Kbm1 | MGI:3618114 | Spontaneous | Khanolkar A, J Immunol 2010 Jul 15;185(2):1132-41 | J:161935 | Mouse_Hepatitis_virus|Pathology | H2-Kbm1Spontaneous |
Khanolkar A, J Immunol 2010 Jul 15;185(2):1132-41 |
||||||||
Hopxtm2.1(cre/ERT2)Joe | MGI:5300731 | Targeted | Inducible|Recombinase | Tang AT, PLoS Biol 2023 Feb;21(2):e3001989 | J:337814 | Pathology|SARS-CoV-2_virus|VOC_B.1.1.529_Omicron | Hopxtm2.1(cre/ERT2)JoeTargeted |
Tang AT, PLoS Biol 2023 Feb;21(2):e3001989 |
|||||||
Hrsq10C57BL/6J | MGI:6404145 | QTL | Gralinski LE, G3 (Bethesda) 2017 Jun 7;7(6):1653-1663 | J:270045 | Pathology|SARS-CoV-MA_virus | Hrsq10C57BL/6JQTL |
Gralinski LE, G3 (Bethesda) 2017 Jun 7;7(6):1653-1663 |
||||||||
Hrsq10PWK/PhJ | MGI:6404144 | QTL | Gralinski LE, G3 (Bethesda) 2017 Jun 7;7(6):1653-1663 | J:270045 | Pathology|SARS-CoV-MA_virus | Hrsq10PWK/PhJQTL |
Gralinski LE, G3 (Bethesda) 2017 Jun 7;7(6):1653-1663 |
||||||||
Hrsq11C57BL/6J | MGI:6404147 | QTL | Gralinski LE, G3 (Bethesda) 2017 Jun 7;7(6):1653-1663 | J:270045 | Pathology|SARS-CoV-MA_virus | Hrsq11C57BL/6JQTL |
Gralinski LE, G3 (Bethesda) 2017 Jun 7;7(6):1653-1663 |
||||||||
Hrsq11PWK/PhJ | MGI:6404146 | QTL | Gralinski LE, G3 (Bethesda) 2017 Jun 7;7(6):1653-1663 | J:270045 | Pathology|SARS-CoV-MA_virus | Hrsq11PWK/PhJQTL |
Gralinski LE, G3 (Bethesda) 2017 Jun 7;7(6):1653-1663 |
||||||||
Hrsq12C57BL/6J | MGI:6404149 | QTL | Gralinski LE, G3 (Bethesda) 2017 Jun 7;7(6):1653-1663 | J:270045 | Pathology|SARS-CoV-MA_virus | Hrsq12C57BL/6JQTL |
Gralinski LE, G3 (Bethesda) 2017 Jun 7;7(6):1653-1663 |
||||||||
Hrsq12PWK/PhJ | MGI:6404148 | QTL | Gralinski LE, G3 (Bethesda) 2017 Jun 7;7(6):1653-1663 | J:270045 | Pathology|SARS-CoV-MA_virus | Hrsq12PWK/PhJQTL |
Gralinski LE, G3 (Bethesda) 2017 Jun 7;7(6):1653-1663 |
||||||||
Hrsq1C57BL/6J | MGI:6403775 | QTL | Gralinski LE, PLoS Genet 2015 Oct;11(10):e1005504 | J:268979 | Infection|SARS-CoV-MA_virus | Hrsq1C57BL/6JQTL |
Gralinski LE, PLoS Genet 2015 Oct;11(10):e1005504 |
||||||||
Hrsq1WSB/EiJ | MGI:6403776 | QTL | Gralinski LE, PLoS Genet 2015 Oct;11(10):e1005504 | J:268979 | Infection|SARS-CoV-MA_virus | Hrsq1WSB/EiJQTL |
Gralinski LE, PLoS Genet 2015 Oct;11(10):e1005504 |
||||||||
Hrsq2PWK/PhJ | MGI:6403777 | QTL | Gralinski LE, PLoS Genet 2015 Oct;11(10):e1005504 | J:268979 | Infection|SARS-CoV-MA_virus | Hrsq2PWK/PhJQTL |
Gralinski LE, PLoS Genet 2015 Oct;11(10):e1005504 |
||||||||
Hrsq3A/J | MGI:6403778 | QTL | Gralinski LE, PLoS Genet 2015 Oct;11(10):e1005504 | J:268979 | Infection|SARS-CoV-MA_virus | Hrsq3A/JQTL |
Gralinski LE, PLoS Genet 2015 Oct;11(10):e1005504 |
||||||||
Hrsq4CAST/EiJ | MGI:6403779 | QTL | Gralinski LE, PLoS Genet 2015 Oct;11(10):e1005504 | J:268979 | Infection|SARS-CoV-MA_virus | Hrsq4CAST/EiJQTL |
Gralinski LE, PLoS Genet 2015 Oct;11(10):e1005504 |
||||||||
Hrsq5C57BL/6J | MGI:6404143 | QTL | Gralinski LE, G3 (Bethesda) 2017 Jun 7;7(6):1653-1663 | J:270045 | Pathology|SARS-CoV-MA_virus | Hrsq5C57BL/6JQTL |
Gralinski LE, G3 (Bethesda) 2017 Jun 7;7(6):1653-1663 |
||||||||
Hrsq5PWK/PhJ | MGI:6404142 | QTL | Gralinski LE, G3 (Bethesda) 2017 Jun 7;7(6):1653-1663 | J:270045 | Pathology|SARS-CoV-MA_virus | Hrsq5PWK/PhJQTL |
Gralinski LE, G3 (Bethesda) 2017 Jun 7;7(6):1653-1663 |
||||||||
Hrsq6C57BL/6J | MGI:6404175 | QTL | Gralinski LE, G3 (Bethesda) 2017 Jun 7;7(6):1653-1663 | J:270045 | Pathology|SARS-CoV-MA_virus | Hrsq6C57BL/6JQTL |
Gralinski LE, G3 (Bethesda) 2017 Jun 7;7(6):1653-1663 |
||||||||
Hrsq6WSB/EiJ | MGI:6404176 | QTL | Gralinski LE, G3 (Bethesda) 2017 Jun 7;7(6):1653-1663 | J:270045 | Pathology|SARS-CoV-MA_virus | Hrsq6WSB/EiJQTL |
Gralinski LE, G3 (Bethesda) 2017 Jun 7;7(6):1653-1663 |
||||||||
Hrsq7129S1/SvImJ | MGI:6404180 | QTL | Gralinski LE, G3 (Bethesda) 2017 Jun 7;7(6):1653-1663 | J:270045 | Pathology|SARS-CoV-MA_virus | Hrsq7129S1/SvImJQTL |
Gralinski LE, G3 (Bethesda) 2017 Jun 7;7(6):1653-1663 |
||||||||
Hrsq7C57BL/6J | MGI:6404178 | QTL | Gralinski LE, G3 (Bethesda) 2017 Jun 7;7(6):1653-1663 | J:270045 | Pathology|SARS-CoV-MA_virus | Hrsq7C57BL/6JQTL |
Gralinski LE, G3 (Bethesda) 2017 Jun 7;7(6):1653-1663 |
||||||||
Hrsq7PWK/PhJ | MGI:6404177 | QTL | Gralinski LE, G3 (Bethesda) 2017 Jun 7;7(6):1653-1663 | J:270045 | Pathology|SARS-CoV-MA_virus | Hrsq7PWK/PhJQTL |
Gralinski LE, G3 (Bethesda) 2017 Jun 7;7(6):1653-1663 |
||||||||
Hrsq7WSB/EiJ | MGI:6404182 | QTL | Gralinski LE, G3 (Bethesda) 2017 Jun 7;7(6):1653-1663 | J:270045 | Pathology|SARS-CoV-MA_virus | Hrsq7WSB/EiJQTL |
Gralinski LE, G3 (Bethesda) 2017 Jun 7;7(6):1653-1663 |
||||||||
Hrsq8CAST/EiJ | MGI:6404186 | QTL | Gralinski LE, G3 (Bethesda) 2017 Jun 7;7(6):1653-1663 | J:270045 | Pathology|SARS-CoV-MA_virus | Hrsq8CAST/EiJQTL |
Gralinski LE, G3 (Bethesda) 2017 Jun 7;7(6):1653-1663 |
||||||||
Hrsq8NOD/ShiLtJ | MGI:6404183 | QTL | Gralinski LE, G3 (Bethesda) 2017 Jun 7;7(6):1653-1663 | J:270045 | Pathology|SARS-CoV-MA_virus | Hrsq8NOD/ShiLtJQTL |
Gralinski LE, G3 (Bethesda) 2017 Jun 7;7(6):1653-1663 |
||||||||
Hrsq8WSB/EiJ | MGI:6404185 | QTL | Gralinski LE, G3 (Bethesda) 2017 Jun 7;7(6):1653-1663 | J:270045 | Pathology|SARS-CoV-MA_virus | Hrsq8WSB/EiJQTL |
Gralinski LE, G3 (Bethesda) 2017 Jun 7;7(6):1653-1663 |
||||||||
Hrsq9129S1/SvImJ | MGI:6404194 | QTL | Gralinski LE, G3 (Bethesda) 2017 Jun 7;7(6):1653-1663 | J:270045 | Pathology|SARS-CoV-MA_virus | Hrsq9129S1/SvImJQTL |
Gralinski LE, G3 (Bethesda) 2017 Jun 7;7(6):1653-1663 |
||||||||
Hrsq9CAST/EiJ | MGI:6404195 | QTL | Gralinski LE, G3 (Bethesda) 2017 Jun 7;7(6):1653-1663 | J:270045 | Pathology|SARS-CoV-MA_virus | Hrsq9CAST/EiJQTL |
Gralinski LE, G3 (Bethesda) 2017 Jun 7;7(6):1653-1663 |
||||||||
Hrsq9NOD/ShiLtJ | MGI:6404192 | QTL | Gralinski LE, G3 (Bethesda) 2017 Jun 7;7(6):1653-1663 | J:270045 | Pathology|SARS-CoV-MA_virus | Hrsq9NOD/ShiLtJQTL |
Gralinski LE, G3 (Bethesda) 2017 Jun 7;7(6):1653-1663 |
||||||||
Hrsq9NZO/HlLtJ | MGI:6404190 | QTL | Gralinski LE, G3 (Bethesda) 2017 Jun 7;7(6):1653-1663 | J:270045 | Pathology|SARS-CoV-MA_virus | Hrsq9NZO/HlLtJQTL |
Gralinski LE, G3 (Bethesda) 2017 Jun 7;7(6):1653-1663 |
||||||||
Hrsq9PWK/PhJ | MGI:6404189 | QTL | Gralinski LE, G3 (Bethesda) 2017 Jun 7;7(6):1653-1663 | J:270045 | Pathology|SARS-CoV-MA_virus | Hrsq9PWK/PhJQTL |
Gralinski LE, G3 (Bethesda) 2017 Jun 7;7(6):1653-1663 |
||||||||
Ido1tm1.1Mkks | MGI:5775113 | Targeted | Null/knockout | Grunewald ME, J Virol 2020 Jan 17;94(3): | J:290586 | Infection|Mouse_Hepatitis_virus | Ido1tm1.1MkksTargeted |
Grunewald ME, J Virol 2020 Jan 17;94(3): |
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Ido1tm1Alm | MGI:3505776 | Targeted | Null/knockout | McDermott JE, BMC Syst Biol 2016 Sep 23;10(1):93 | J:288523 | Pathology|SARS-CoV-MA_virus | Ido1tm1AlmTargeted |
McDermott JE, BMC Syst Biol 2016 Sep 23;10(1):93 |
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Ifih1tm1.1Cln | MGI:3663677 | Targeted | Null/knockout | Menachery VD, J Virol 2014 Apr;88(8):4251-64 Zalinger ZB, J Virol 2015 Dec 15;89(24):12330-40 Deng X, Proc Natl Acad Sci U S A 2017 May 23;114(21):E4251-E4260 Zheng M, Nat Immunol 2021 Jul;22(7):829-838 Birdwell LD, J Virol 2016 Jan 6;90(6):3160-72 | J:213001 J:227926 J:242293 J:308903 J:318622 | SARS-CoV-MA_virus|SARS-CoV_virus|Treatment|Vaccine Infection|Mouse_Hepatitis_virus Pathology|SARS-CoV-2_virus Mouse_Hepatitis_virus | Ifih1tm1.1ClnTargeted |
Menachery VD, J Virol 2014 Apr;88(8):4251-64 Zalinger ZB, J Virol 2015 Dec 15;89(24):12330-40 Deng X, Proc Natl Acad Sci U S A 2017 May 23;114(21):E4251-E4260 Zheng M, Nat Immunol 2021 Jul;22(7):829-838 Birdwell LD, J Virol 2016 Jan 6;90(6):3160-72 |
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Ifih1tm1Aki | MGI:3801032 | Targeted | Null/knockout | Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 | J:296686 | Pathology|SARS-CoV-2_virus|Treatment | Ifih1tm1AkiTargeted |
Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 |
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Ifit1tm1(KOMP)Vlcg | MGI:3808310 | Targeted | Null/knockout|Reporter | MGI:6436931 | growth/size/body hematopoietic system homeostasis/metabolism immune system nervous system mortality/aging | MP:0005378 MP:0005397 MP:0005376 MP:0005387 MP:0003631 MP:0010768 | Daffis S, Nature 2010 Nov 18;468(7322):452-6 Butchi NB, J Virol 2014 Jan;88(2):1051-64 Menachery VD, J Virol 2014 Apr;88(8):4251-64 | J:187561 J:205203 J:213001 | Mouse_Hepatitis_virus SARS-CoV-MA_virus|SARS-CoV_virus|Treatment|Vaccine | Ifit1tm1(KOMP)VlcgTargeted |
MGI:6436931 | growth/size/body hematopoietic system homeostasis/metabolism immune system nervous system mortality/aging |
Daffis S, Nature 2010 Nov 18;468(7322):452-6 Butchi NB, J Virol 2014 Jan;88(2):1051-64 Menachery VD, J Virol 2014 Apr;88(8):4251-64 |
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Ifit2tm1(KOMP)Vlcg | MGI:3799963 | Targeted | Null/knockout|Reporter | Das Sarma J, PLoS Pathog 2020 Nov;16(11):e1009034 | J:313166 | Mouse_Hepatitis_virus | Ifit2tm1(KOMP)VlcgTargeted |
Das Sarma J, PLoS Pathog 2020 Nov;16(11):e1009034 |
|||||||
Ifitm3em1Jsy | MGI:6362958 | Endonuclease-mediated | Null/knockout | Zani A, bioRxiv 2021Dec;(): | J:316764 | Gene|SARS-CoV-2-MA_virus|SARS-CoV-2_virus | Ifitm3em1JsyEndonuclease-mediated |
Zani A, bioRxiv 2021Dec;(): |
|||||||
Ifnar1tm1.1Ees | MGI:5692160 | Targeted | Conditional ready|No functional change | Anand G, bioRxiv 2020 Dec;(): | J:298270 | Pathology|SARS-CoV-2_virus | Ifnar1tm1.1EesTargeted |
Anand G, bioRxiv 2020 Dec;(): |
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Ifnar1tm1.2Ees | MGI:5692167 | Targeted | Null/knockout | Israelow B, J Exp Med 2020 Dec 7;217(12): Sun J, Cell 2020 Jun 10;(): Yang J, Nature 2020 Jul 29;(): Mao T, bioRxiv 2021 Jun;(): Tada T, Proc Natl Acad Sci U S A 2023 Jun 6;120(23):e2303509120 Hilligan KL, Nat Commun 2023 Dec 12;14(1):8229 | J:291862 J:291881 J:292665 J:308656 J:338414 J:343550 | Infection|Pathology|SARS-CoV-2_virus Infection|Pathology|SARS-CoV-2_virus|Treatment SARS-CoV-2_virus|Vaccine Treatment|VOC_B.1.1.7_Alpha|VOC_B.1.351_Beta|VOC_P.1_Gamma SARS-CoV-2_virus|Treatment|VOC_B.1.1.529_Omicron Infection|SARS-CoV-2_virus|Treatment | Ifnar1tm1.2EesTargeted |
Israelow B, J Exp Med 2020 Dec 7;217(12): Sun J, Cell 2020 Jun 10;(): Yang J, Nature 2020 Jul 29;(): Mao T, bioRxiv 2021 Jun;(): Tada T, Proc Natl Acad Sci U S A 2023 Jun 6;120(23):e2303509120 Hilligan KL, Nat Commun 2023 Dec 12;14(1):8229 |
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Ifnar1tm1Agt | MGI:1930950 | Targeted | Null/knockout | MGI:2654514 MGI:3575517 MGI:6449667 | behavior/neurological cardiovascular system hematopoietic system homeostasis/metabolism immune system liver/biliary system vision/eye mortality/aging cellular | MP:0005386 MP:0005385 MP:0005397 MP:0005376 MP:0005387 MP:0005370 MP:0005391 MP:0010768 MP:0005384 | Cervantes-Barragan L, J Immunol 2009 Jan 15;182(2):1099-106 Cervantes-Barragan L, Blood 2007 Feb 1;109(3):1131-7 Ireland DD, J Virol 2008 Jan;82(1):300-10 Phares TW, J Immunol 2009 May 1;182(9):5430-8 Daffis S, Nature 2010 Nov 18;468(7322):452-6 Zhao J, Proc Natl Acad Sci U S A 2014 Apr 1;111(13):4970-5 Menachery VD, J Virol 2014 Apr;88(8):4251-64 Deng X, J Virol 2014 Oct 15;88(20):11886-98 Fehr AR, J Virol 2015 Feb;89(3):1523-36 Deng X, Proc Natl Acad Sci U S A 2017 May 23;114(21):E4251-E4260 Peng X, mBio 2010 Oct 26;1(5): Frieman MB, PLoS Pathog 2010 Apr 8;6(4):e1000849 Hassan AO, Cell 2020 Jun 10;(): Channappanavar R, Cell Host Microbe 2016 Feb 10;19(2):181-93 Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 Miner JJ, Cell Rep 2020 Nov 3;33(5):108339 Horner C, Proc Natl Acad Sci U S A 2020 Dec 22;117(51):32657-32666 Malczyk AH, J Virol 2015 Nov;89(22):11654-67 Xiao Y, Cell 2021 Dec 9;184(25):6037-6051.e14 Birdwell LD, J Virol 2016 Jan 6;90(6):3160-72 Hassert M, PLoS Pathog 2020 Dec;16(12):e1009163 Ngo VL, Cell Host Microbe 2024 Jan 23;(): | J:143484 J:144400 J:145215 J:147948 J:187561 J:207380 J:213001 J:214600 J:221981 J:242293 J:276986 J:286237 J:290258 J:291874 J:296686 J:300094 J:300105 J:312515 J:317125 J:318622 J:319459 J:345954 | Mouse_Hepatitis_virus Infection|Mouse_Hepatitis_virus|SARS-CoV_virus Infection|Mouse_Hepatitis_virus MERS-CoV_virus SARS-CoV-MA_virus|SARS-CoV_virus|Treatment|Vaccine Mouse_Hepatitis_virus|Pathology Infection|SARS-CoV-MA_virus Pathology|SARS-CoV-MA_virus Infection|SARS-CoV-2_virus|Treatment Gene|Infection|Pathology|SARS-CoV-MA_virus Pathology|SARS-CoV-2_virus|Treatment SARS-CoV-2_virus SARS-CoV-2_virus|Vaccine MERS-CoV_virus|Vaccine SARS-CoV-2_virus|Treatment|VOC_B.1.1.7_Alpha|VOC_B.1.427|VOC_B.1.617.2_Delta Infection|SARS-CoV-2_virus Infection|MERS-CoV-MA_virus | Ifnar1tm1AgtTargeted |
MGI:2654514 MGI:3575517 MGI:6449667 | behavior/neurological cardiovascular system hematopoietic system homeostasis/metabolism immune system liver/biliary system vision/eye mortality/aging cellular |
Cervantes-Barragan L, J Immunol 2009 Jan 15;182(2):1099-106 Cervantes-Barragan L, Blood 2007 Feb 1;109(3):1131-7 Ireland DD, J Virol 2008 Jan;82(1):300-10 Phares TW, J Immunol 2009 May 1;182(9):5430-8 Daffis S, Nature 2010 Nov 18;468(7322):452-6 Zhao J, Proc Natl Acad Sci U S A 2014 Apr 1;111(13):4970-5 Menachery VD, J Virol 2014 Apr;88(8):4251-64 Deng X, J Virol 2014 Oct 15;88(20):11886-98 Fehr AR, J Virol 2015 Feb;89(3):1523-36 Deng X, Proc Natl Acad Sci U S A 2017 May 23;114(21):E4251-E4260 Peng X, mBio 2010 Oct 26;1(5): Frieman MB, PLoS Pathog 2010 Apr 8;6(4):e1000849 Hassan AO, Cell 2020 Jun 10;(): Channappanavar R, Cell Host Microbe 2016 Feb 10;19(2):181-93 Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 Miner JJ, Cell Rep 2020 Nov 3;33(5):108339 Horner C, Proc Natl Acad Sci U S A 2020 Dec 22;117(51):32657-32666 Malczyk AH, J Virol 2015 Nov;89(22):11654-67 Xiao Y, Cell 2021 Dec 9;184(25):6037-6051.e14 Birdwell LD, J Virol 2016 Jan 6;90(6):3160-72 Hassert M, PLoS Pathog 2020 Dec;16(12):e1009163 Ngo VL, Cell Host Microbe 2024 Jan 23;(): |
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Ifnar1tm1Pjh | MGI:2667975 | Targeted | Null/knockout | Rawle DJ, bioRxiv 2021 Feb;(): Ogger PP, Eur J Immunol 2022 Nov;52(11):1768-1775 | J:302157 J:333792 | SARS-CoV-2_virus Infection|SARS-CoV-2_virus | Ifnar1tm1PjhTargeted |
Rawle DJ, bioRxiv 2021 Feb;(): Ogger PP, Eur J Immunol 2022 Nov;52(11):1768-1775 |
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Ifnar1tm1Uka | MGI:2655303 | Targeted | Conditional ready|No functional change | Cervantes-Barragan L, J Immunol 2009 Jan 15;182(2):1099-106 | J:143484 | Mouse_Hepatitis_virus | Ifnar1tm1UkaTargeted |
Cervantes-Barragan L, J Immunol 2009 Jan 15;182(2):1099-106 |
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Ifnar2tm1Pjh | MGI:2680693 | Targeted | Null/knockout | Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 Rawle DJ, bioRxiv 2021 Feb;(): | J:296686 J:302157 | Pathology|SARS-CoV-2_virus|Treatment SARS-CoV-2_virus | Ifnar2tm1PjhTargeted |
Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 Rawle DJ, bioRxiv 2021 Feb;(): |
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Ifngr1tm1Agt | MGI:1857286 | Targeted | Null/knockout | MGI:3575517 MGI:6403197 | hematopoietic system immune system mortality/aging | MP:0005397 MP:0005387 MP:0010768 | Templeton SP, J Neuroimmunol 2008 Feb;194(1-2):18-26 Frieman MB, PLoS Pathog 2010 Apr 8;6(4):e1000849 Hassan AO, Cell 2020 Jun 10;(): Miner JJ, Cell Rep 2020 Nov 3;33(5):108339 Schijns VE, J Immunol 1996 Jul 15;157(2):815-21 Hilligan KL, Nat Commun 2023 Dec 12;14(1):8229 | J:131907 J:286237 J:290258 J:300094 J:34040 J:343550 | Mouse_Hepatitis_virus Pathology|SARS-CoV-MA_virus Infection|SARS-CoV-2_virus|Treatment SARS-CoV-2_virus | Ifngr1tm1AgtTargeted |
MGI:3575517 MGI:6403197 | hematopoietic system immune system mortality/aging |
Templeton SP, J Neuroimmunol 2008 Feb;194(1-2):18-26 Frieman MB, PLoS Pathog 2010 Apr 8;6(4):e1000849 Hassan AO, Cell 2020 Jun 10;(): Miner JJ, Cell Rep 2020 Nov 3;33(5):108339 Schijns VE, J Immunol 1996 Jul 15;157(2):815-21 Hilligan KL, Nat Commun 2023 Dec 12;14(1):8229 |
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Ifngtm1Ts | MGI:1857184 | Targeted | Null/knockout | MGI:4365971 | endocrine/exocrine glands hematopoietic system immune system neoplasm mortality/aging | MP:0005379 MP:0005397 MP:0005387 MP:0002006 MP:0010768 | Parra B, J Immunol 1999 Feb 1;162(3):1641-7 Phares TW, J Immunol 2009 May 1;182(9):5430-8 Malone KE, Glia 2008 Mar;56(4):426-35 Sun J, Cell 2020 Jun 10;(): Savarin C, J Neuroinflammation 2012 May 29;9():104 France MP, Aust Vet J 1999 Sep;77(9):600-4 Dandekar AA, Am J Pathol 2004 Feb;164(2):363-9 | J:112048 J:147948 J:156284 J:291881 J:331807 J:59661 J:88552 | Infection|Mouse_Hepatitis_virus Mouse_Hepatitis_virus Infection|Pathology|SARS-CoV-2_virus|Treatment Mouse_Hepatitis_virus|Pathology | Ifngtm1TsTargeted |
MGI:4365971 | endocrine/exocrine glands hematopoietic system immune system neoplasm mortality/aging |
Parra B, J Immunol 1999 Feb 1;162(3):1641-7 Phares TW, J Immunol 2009 May 1;182(9):5430-8 Malone KE, Glia 2008 Mar;56(4):426-35 Sun J, Cell 2020 Jun 10;(): Savarin C, J Neuroinflammation 2012 May 29;9():104 France MP, Aust Vet J 1999 Sep;77(9):600-4 Dandekar AA, Am J Pathol 2004 Feb;164(2):363-9 |
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Ifngtm1Yiw | MGI:3036127 | Targeted | Null/knockout | MGI:6430478 MGI:6430488 | behavior/neurological digestive/alimentary system growth/size/body homeostasis/metabolism immune system liver/biliary system mortality/aging | MP:0005386 MP:0005381 MP:0005378 MP:0005376 MP:0005387 MP:0005370 MP:0010768 | Kyuwa S, J Virol 1998 Nov;72(11):9286-90 Kyuwa S, Virus Res 2002 Feb 26;83(1-2):169-77 | J:50405 J:91691 | Mouse_Hepatitis_virus|Pathology Infection|Mouse_Hepatitis_virus|Pathology | Ifngtm1YiwTargeted |
MGI:6430478 MGI:6430488 | behavior/neurological digestive/alimentary system growth/size/body homeostasis/metabolism immune system liver/biliary system mortality/aging |
Kyuwa S, J Virol 1998 Nov;72(11):9286-90 Kyuwa S, Virus Res 2002 Feb 26;83(1-2):169-77 |
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Ifnl2tm1.1Arte | MGI:7493919 | Targeted | No functional change|Reporter | Chong Z, Cell Rep 2022 May 10;39(6):110799 | J:325089 | SARS-CoV-2_virus|Treatment|VOC_B.1.1.529_Omicron|VOC_B.1.351_Beta | Ifnl2tm1.1ArteTargeted |
Chong Z, Cell Rep 2022 May 10;39(6):110799 |
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Ifnlr1tm1Palu | MGI:3775762 | Targeted | Null/knockout | MGI:6403849 | immune system | MP:0005387 | Frieman MB, PLoS Pathog 2010 Apr 8;6(4):e1000849 Miner JJ, Cell Rep 2020 Nov 3;33(5):108339 Chong Z, bioRxiv 2022;(): Chong Z, Cell Rep 2022 May 10;39(6):110799 | J:286237 J:300094 J:321761 J:325089 | Pathology|SARS-CoV-MA_virus SARS-CoV-2_virus SARS-CoV-2_virus|Treatment|VOC_B.1.1.529_Omicron|VOC_B.1.351_Beta | Ifnlr1tm1PaluTargeted |
MGI:6403849 | immune system |
Frieman MB, PLoS Pathog 2010 Apr 8;6(4):e1000849 Miner JJ, Cell Rep 2020 Nov 3;33(5):108339 Chong Z, bioRxiv 2022;(): Chong Z, Cell Rep 2022 May 10;39(6):110799 |
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Ighem1Rcas | MGI:6725128 | Endonuclease-mediated | Inserted expressed sequence | Xu J, Nature 2021 Jun 7;(): | J:307753 | SARS-CoV-2_virus|Treatment|VOC_B.1.1.7_Alpha|VOC_B.1.351_Beta|VOC_P.1_Gamma | Ighem1RcasEndonuclease-mediated |
Xu J, Nature 2021 Jun 7;(): |
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Igh-Jtm1Dhu | MGI:2158307 | Targeted | Null/knockout | Afkhami S, bioRxiv 2021 Jul;(): | J:308640 | SARS-CoV-2_virus|Vaccine|VOC_B.1.1.7_Alpha|VOC_B.1.351_Beta | Igh-Jtm1DhuTargeted |
Afkhami S, bioRxiv 2021 Jul;(): |
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Ighmtm1Cgn | MGI:1857187 | Targeted | Null/knockout | Bergmann CC, J Immunol 2001 Aug 1;167(3):1575-83 Zhao J, Proc Natl Acad Sci U S A 2014 Apr 1;111(13):4970-5 Israelow B, bioRxiv 2021 May;(): Sarden N, Sci Transl Med 2022 Dec 7;14(674):eabq6682 | J:120484 J:207380 J:308733 J:336666 | Mouse_Hepatitis_virus MERS-CoV_virus Infection|SARS-CoV-2_virus Comorbidity|SARS-CoV-2_virus | Ighmtm1CgnTargeted |
Bergmann CC, J Immunol 2001 Aug 1;167(3):1575-83 Zhao J, Proc Natl Acad Sci U S A 2014 Apr 1;111(13):4970-5 Israelow B, bioRxiv 2021 May;(): Sarden N, Sci Transl Med 2022 Dec 7;14(674):eabq6682 |
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Ightm3.1(VRC01)Nemz | MGI:5779356 | Targeted | Inserted expressed sequence | Luo Y, Signal Transduct Target Ther 2022 Jan 4;7(1):7 | J:333746 | SARS-CoV-2_virus|Vaccine | Ightm3.1(VRC01)NemzTargeted |
Luo Y, Signal Transduct Target Ther 2022 Jan 4;7(1):7 |
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Igs2em1(KRT18-ACE2)Gpt | MGI:6452440 | Endonuclease-mediated | Inserted expressed sequence | Yu S, Proc Natl Acad Sci U S A 2022 Jan 4;119(1):e2111199119 Yuan Y, bioRxiv 2022 Feb;(): | J:318831 J:321891 | Infection|SARS-CoV-2_virus Vaccine|VOC_B.1.617.2_Delta | Igs2em1(KRT18-ACE2)GptEndonuclease-mediated |
Yu S, Proc Natl Acad Sci U S A 2022 Jan 4;119(1):e2111199119 Yuan Y, bioRxiv 2022 Feb;(): |
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Ikbkbtm2Mka | MGI:2445462 | Targeted | Conditional ready|No functional change | Satta S, Theranostics 2022;12(6):2639-2657 | J:331825 | SARS-CoV-2_virus|Variant | Ikbkbtm2MkaTargeted |
Satta S, Theranostics 2022;12(6):2639-2657 |
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Ikbkgtm1.1Mpa | MGI:2679024 | Targeted | Conditional ready|No functional change | Wenzel J, Nat Neurosci 2021 Nov;24(11):1522-1533 | J:323957 | Pathology|SARS-CoV-2_virus|VOC_B.1.351_Beta | Ikbkgtm1.1MpaTargeted |
Wenzel J, Nat Neurosci 2021 Nov;24(11):1522-1533 |
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Il10tm1.1Karp | MGI:4355198 | Targeted | Reporter | Trandem K, J Immunol 2011 Mar 15;186(6):3642-52 | J:169759 | Mouse_Hepatitis_virus|Pathology | Il10tm1.1KarpTargeted |
Trandem K, J Immunol 2011 Mar 15;186(6):3642-52 |
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Il10tm1Cgn | MGI:1857199 | Targeted | Null/knockout | Trandem K, J Immunol 2011 Mar 15;186(6):3642-52 Puntambekar SS, Glia 2015 Jun 30;(): | J:169759 J:225834 | Mouse_Hepatitis_virus|Pathology Mouse_Hepatitis_virus | Il10tm1CgnTargeted |
Trandem K, J Immunol 2011 Mar 15;186(6):3642-52 Puntambekar SS, Glia 2015 Jun 30;(): |
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Il17aem1Cya | MGI:6695195 | Endonuclease-mediated | Null/knockout | Lin X, iScience 2021 Apr 23;24(4):102293 | J:304178 | Pathology|SARS-CoV-2_virus|Treatment | Il17aem1CyaEndonuclease-mediated |
Lin X, iScience 2021 Apr 23;24(4):102293 |
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Il18r1tm1Aki | MGI:2136765 | Targeted | Null/knockout | Sheahan T, PLoS Pathog 2008 Dec;4(12):e1000240 Zalinger ZB, J Neurovirol 2017 Dec;23(6):845-854 | J:162707 J:331829 | Pathology|SARS-CoV-MA_virus Mouse_Hepatitis_virus | Il18r1tm1AkiTargeted |
Sheahan T, PLoS Pathog 2008 Dec;4(12):e1000240 Zalinger ZB, J Neurovirol 2017 Dec;23(6):845-854 |
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Il1btm1Yiw | MGI:2157396 | Targeted | Null/knockout|Reporter | Yang J, Nature 2020 Jul 29;(): | J:292665 | SARS-CoV-2_virus|Vaccine | Il1btm1YiwTargeted |
Yang J, Nature 2020 Jul 29;(): |
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Il1r1tm1Imx | MGI:1861112 | Targeted | Null/knockout | Sheahan T, PLoS Pathog 2008 Dec;4(12):e1000240 Zalinger ZB, J Neurovirol 2017 Dec;23(6):845-854 | J:162707 J:331829 | Pathology|SARS-CoV-MA_virus Mouse_Hepatitis_virus | Il1r1tm1ImxTargeted |
Sheahan T, PLoS Pathog 2008 Dec;4(12):e1000240 Zalinger ZB, J Neurovirol 2017 Dec;23(6):845-854 |
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Il2rgem26Gpt | MGI:5827573 | Endonuclease-mediated | Not Specified | Hu Z, bioRxiv 2021 Nov;(): | J:313461 | Infection|SARS-CoV-2_virus | Il2rgem26GptEndonuclease-mediated |
Hu Z, bioRxiv 2021 Nov;(): |
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Il2rgtm1.1Flv | MGI:4887837 | Targeted | Null/knockout | Sefik E, bioRxiv 2021;(): | J:311907 | SARS-CoV-2_virus | Il2rgtm1.1FlvTargeted |
Sefik E, bioRxiv 2021;(): |
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Il2rgtm1Wjl | MGI:1857455 | Targeted | Null/knockout | Halwe S, bioRxiv 2021 Jun;(): Ngo VL, Cell Host Microbe 2024 Jan 23;(): | J:308648 J:345954 | SARS-CoV-2_virus|Treatment|VOC_B.1.1.7_Alpha|VOC_B.1.351_Beta Infection|MERS-CoV-MA_virus | Il2rgtm1WjlTargeted |
Halwe S, bioRxiv 2021 Jun;(): Ngo VL, Cell Host Microbe 2024 Jan 23;(): |
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Il6ratm1.1Drew | MGI:4456449 | Targeted | Conditional ready|No functional change | Harb H, Immunity 2021 Apr 22;(): | J:347529 | Infection | Il6ratm1.1DrewTargeted |
Harb H, Immunity 2021 Apr 22;(): |
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Il6tm1Kopf | MGI:1857197 | Targeted | Null/knockout | MGI:3837132 | hematopoietic system homeostasis/metabolism immune system liver/biliary system nervous system mortality/aging | MP:0005397 MP:0005376 MP:0005387 MP:0005370 MP:0003631 MP:0010768 | Imai Y, Cell 2008 Apr 18;133(2):235-49 Kumaki Y, Antiviral Res 2017 Mar;139():1-12 Ndeupen S, bioRxiv 2021 Aug;(): Alameh MG, Immunity 2021 Dec 14;54(12):2877-2892.e7 | J:145306 J:286953 J:308580 J:337329 | SARS-CoV_virus SARS-CoV-MA_virus|SARS-CoV_virus|Treatment SARS-CoV-2_virus|Vaccine | Il6tm1KopfTargeted |
MGI:3837132 | hematopoietic system homeostasis/metabolism immune system liver/biliary system nervous system mortality/aging |
Imai Y, Cell 2008 Apr 18;133(2):235-49 Kumaki Y, Antiviral Res 2017 Mar;139():1-12 Ndeupen S, bioRxiv 2021 Aug;(): Alameh MG, Immunity 2021 Dec 14;54(12):2877-2892.e7 |
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Il6tm2(IL6)Flv | MGI:6405713 | Targeted | Humanized sequence|Inserted expressed sequence|Null/knockout | Sefik E, bioRxiv 2021;(): | J:311907 | SARS-CoV-2_virus | Il6tm2(IL6)FlvTargeted |
Sefik E, bioRxiv 2021;(): |
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Irf1tm1Mak | MGI:1857205 | Targeted | Null/knockout | Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 | J:296686 | Pathology|SARS-CoV-2_virus|Treatment | Irf1tm1MakTargeted |
Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 |
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Irf3tm1Ttg | MGI:3577601 | Targeted | Null/knockout | Imai Y, Cell 2008 Apr 18;133(2):235-49 Daffis S, Nature 2010 Nov 18;468(7322):452-6 Israelow B, J Exp Med 2020 Dec 7;217(12): Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 | J:145306 J:187561 J:291862 J:296686 | SARS-CoV_virus Mouse_Hepatitis_virus Infection|Pathology|SARS-CoV-2_virus Pathology|SARS-CoV-2_virus|Treatment | Irf3tm1TtgTargeted |
Imai Y, Cell 2008 Apr 18;133(2):235-49 Daffis S, Nature 2010 Nov 18;468(7322):452-6 Israelow B, J Exp Med 2020 Dec 7;217(12): Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 |
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Irf5tm1Ppr | MGI:5291913 | Targeted | Conditional ready|No functional change | Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 | J:296686 | Pathology|SARS-CoV-2_virus|Treatment | Irf5tm1PprTargeted |
Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 |
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Irf7tm1Ttg | MGI:3577089 | Targeted | Null/knockout | Daffis S, Nature 2010 Nov 18;468(7322):452-6 Israelow B, J Exp Med 2020 Dec 7;217(12): Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 | J:187561 J:291862 J:296686 | Mouse_Hepatitis_virus Infection|Pathology|SARS-CoV-2_virus Pathology|SARS-CoV-2_virus|Treatment | Irf7tm1TtgTargeted |
Daffis S, Nature 2010 Nov 18;468(7322):452-6 Israelow B, J Exp Med 2020 Dec 7;217(12): Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 |
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Irf9tm1Ttg | MGI:2446102 | Targeted | Null/knockout | Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 | J:296686 | Pathology|SARS-CoV-2_virus|Treatment | Irf9tm1TtgTargeted |
Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 |
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Kctd9em1Beij | MGI:6382731 | Endonuclease-mediated | Null/knockout | MGI:6382782 | hematopoietic system homeostasis/metabolism immune system mortality/aging | MP:0005397 MP:0005376 MP:0005387 MP:0010768 | Zhang X, Front Immunol 2019;10():744 | J:281803 | Mouse_Hepatitis_virus | Kctd9em1BeijEndonuclease-mediated |
MGI:6382782 | hematopoietic system homeostasis/metabolism immune system mortality/aging |
Zhang X, Front Immunol 2019;10():744 |
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Ldlrtm1Her | MGI:1857212 | Targeted | Null/knockout | Ensor CM, bioRxiv 2021-09;(): | J:310122 | SARS-CoV-2_virus | Ldlrtm1HerTargeted |
Ensor CM, bioRxiv 2021-09;(): |
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Leprdb | MGI:1856009 | Spontaneous | Choi JY, Biochem Biophys Res Commun 2020 Jul 30;528(3):413-419 Vergara A, Mol Cell Endocrinol 2021 Jun 1;529():111263 | J:292007 J:308897 | Gene Comorbidity | LeprdbSpontaneous |
Choi JY, Biochem Biophys Res Commun 2020 Jul 30;528(3):413-419 Vergara A, Mol Cell Endocrinol 2021 Jun 1;529():111263 |
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Ltb4r1tm1Adl | MGI:2385786 | Targeted | Null/knockout | Sarden N, Sci Transl Med 2022 Dec 7;14(674):eabq6682 | J:336666 | Comorbidity|SARS-CoV-2_virus | Ltb4r1tm1AdlTargeted |
Sarden N, Sci Transl Med 2022 Dec 7;14(674):eabq6682 |
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Ly6etm1a(EUCOMM)Hmgu | MGI:5428615 | Targeted | Conditional ready|Null/knockout|Reporter | Pfaender S, Nat Microbiol 2020 Jul 23;(): | J:291868 | Gene|HCoV-229E_virus|HCoV-OC43_virus|MERS-CoV_virus|Mouse_Hepatitis_virus|SARS-CoV-2_virus|SARS-CoV_virus | Ly6etm1a(EUCOMM)HmguTargeted |
Pfaender S, Nat Microbiol 2020 Jul 23;(): |
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Ly6etm1c(EUCOMM)Hmgu | MGI:6448980 | Targeted | Conditional ready | Pfaender S, Nat Microbiol 2020 Jul 23;(): | J:291868 | Gene|HCoV-229E_virus|HCoV-OC43_virus|MERS-CoV_virus|Mouse_Hepatitis_virus|SARS-CoV-2_virus|SARS-CoV_virus | Ly6etm1c(EUCOMM)HmguTargeted |
Pfaender S, Nat Microbiol 2020 Jul 23;(): |
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Lystbg-J | MGI:1855969 | Spontaneous | Glass WG, J Immunol 2004 Sep 15;173(6):4030-9 | J:92752 | Infection|SARS-CoV_virus | Lystbg-JSpontaneous |
Glass WG, J Immunol 2004 Sep 15;173(6):4030-9 |
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Lyz2tm1(cre)Ifo | MGI:1934631 | Targeted | Recombinase | Cervantes-Barragan L, J Immunol 2009 Jan 15;182(2):1099-106 Imai Y, Cell 2008 Apr 18;133(2):235-49 Zhao Z, Autophagy 2007 Nov-Dec;3(6):581-5 Page C, J Virol 2012 Dec;86(24):13334-49 Melvin WJ, Proc Natl Acad Sci U S A 2021 Sep 21;118(38):e2101071118 Musiu C, Cell Death Differ 2021 Sep 13;(): Verma AK, mBio 2021 Oct 26;12(5):e0196921 Wang Y, Sci Adv 2021 Jan;7(1): de Almeida L, Sci Adv 2022 Sep 16;8(37):eabo5400 Satta S, Theranostics 2022;12(6):2639-2657 | J:143484 J:145306 J:282479 J:286337 J:311033 J:313338 J:313438 J:314537 J:331763 J:331825 | Mouse_Hepatitis_virus SARS-CoV_virus Pathology|SARS-CoV_virus Comorbidity|Gene|Mouse_Hepatitis_virus Pathology|SARS-CoV-2_virus SARS-CoV-2_virus SARS-CoV-2_virus|Variant | Lyz2tm1(cre)IfoTargeted |
Cervantes-Barragan L, J Immunol 2009 Jan 15;182(2):1099-106 Imai Y, Cell 2008 Apr 18;133(2):235-49 Zhao Z, Autophagy 2007 Nov-Dec;3(6):581-5 Page C, J Virol 2012 Dec;86(24):13334-49 Melvin WJ, Proc Natl Acad Sci U S A 2021 Sep 21;118(38):e2101071118 Musiu C, Cell Death Differ 2021 Sep 13;(): Verma AK, mBio 2021 Oct 26;12(5):e0196921 Wang Y, Sci Adv 2021 Jan;7(1): de Almeida L, Sci Adv 2022 Sep 16;8(37):eabo5400 Satta S, Theranostics 2022;12(6):2639-2657 |
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Mavstm1Aki | MGI:3773161 | Targeted | Null/knockout | Zhao J, Proc Natl Acad Sci U S A 2014 Apr 1;111(13):4970-5 Channappanavar R, J Clin Invest 2019 Jul 29;130():3625-3639 Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 Zheng M, Nat Immunol 2021 Jul;22(7):829-838 | J:207380 J:288107 J:296686 J:308903 | MERS-CoV_virus Infection|MERS-CoV-MA_virus|Treatment Pathology|SARS-CoV-2_virus|Treatment Pathology|SARS-CoV-2_virus | Mavstm1AkiTargeted |
Zhao J, Proc Natl Acad Sci U S A 2014 Apr 1;111(13):4970-5 Channappanavar R, J Clin Invest 2019 Jul 29;130():3625-3639 Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 Zheng M, Nat Immunol 2021 Jul;22(7):829-838 |
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Mavstm1Zjc | MGI:3654145 | Targeted | Null/knockout | Alameh MG, Immunity 2021 Dec 14;54(12):2877-2892.e7 | J:337329 | SARS-CoV-2_virus|Vaccine | Mavstm1ZjcTargeted |
Alameh MG, Immunity 2021 Dec 14;54(12):2877-2892.e7 |
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Mbd2em1Wgcy | MGI:6825813 | Endonuclease-mediated | Conditional ready|No functional change | Wang Y, Sci Adv 2021 Jan;7(1): | J:314537 | SARS-CoV-2_virus | Mbd2em1WgcyEndonuclease-mediated |
Wang Y, Sci Adv 2021 Jan;7(1): |
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Mcph1Tg(HLA-A2.1)1Enge | MGI:3056375 | Transgenic | Humanized sequence|Inserted expressed sequence|Null/knockout | Carter B, bioRxiv 2021 May;(): | J:308712 | SARS-CoV-2_virus|Vaccine | Mcph1Tg(HLA-A2.1)1EngeTransgenic |
Carter B, bioRxiv 2021 May;(): |
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Mlkltm1.2Wsa | MGI:5614464 | Targeted | Null/knockout | Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 Zheng M, J Biol Chem 2020 Oct 9;295(41):14040-14052 | J:296686 J:298138 | Pathology|SARS-CoV-2_virus|Treatment Mouse_Hepatitis_virus | Mlkltm1.2WsaTargeted |
Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 Zheng M, J Biol Chem 2020 Oct 9;295(41):14040-14052 |
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Mmp14tm1Ktry | MGI:2386246 | Targeted | Null/knockout | Guo X, Nat Commun 2022 Dec 23;13(1):7907 | J:333743 | SARS-CoV-2_virus | Mmp14tm1KtryTargeted |
Guo X, Nat Commun 2022 Dec 23;13(1):7907 |
|||||||
Muc16tm1Bhr | MGI:3840843 | Targeted | Null/knockout | Biering SB, Nat Genet 2022 Aug;54(8):1078-1089 | J:331758 | SARS-CoV-2-MA_virus|SARS-CoV-2_virus | Muc16tm1BhrTargeted |
Biering SB, Nat Genet 2022 Aug;54(8):1078-1089 |
|||||||
Muc1tm1Gend | MGI:2447730 | Targeted | Null/knockout | Biering SB, Nat Genet 2022 Aug;54(8):1078-1089 | J:331758 | SARS-CoV-2-MA_virus|SARS-CoV-2_virus | Muc1tm1GendTargeted |
Biering SB, Nat Genet 2022 Aug;54(8):1078-1089 |
|||||||
Muc4PWK/PhJ | MGI:6423091 | Not Applicable | Hypomorph | MGI:6423103 | immune system | MP:0005387 | Plante JA, bioRxiv 2020;(): | J:287566 | Infection|SARS-CoV-MA_virus|Sex_bias | Muc4PWK/PhJNot Applicable |
MGI:6423103 | immune system |
Plante JA, bioRxiv 2020;(): |
||
Muc4tm1Unc | MGI:6416171 | Targeted | Null/knockout | MGI:6423102 | Coronavirus infectious disease | DOID:0080599 | growth/size/body immune system respiratory system mortality/aging | MP:0005378 MP:0005387 MP:0005388 MP:0010768 | Plante JA, bioRxiv 2020;(): Biering SB, Nat Genet 2022 Aug;54(8):1078-1089 | J:287566 J:331758 | Infection|SARS-CoV-MA_virus|Sex_bias SARS-CoV-2-MA_virus|SARS-CoV-2_virus | Muc4tm1UncTargeted |
MGI:6423102 | growth/size/body immune system respiratory system mortality/aging Coronavirus infectious disease |
Plante JA, bioRxiv 2020;(): Biering SB, Nat Genet 2022 Aug;54(8):1078-1089 |
Mx1tm1.1Agsa | MGI:6275981 | Targeted | Inducible|Inserted expressed sequence|Null/knockout|Reporter | Anand G, bioRxiv 2020 Dec;(): | J:298270 | Pathology|SARS-CoV-2_virus | Mx1tm1.1AgsaTargeted |
Anand G, bioRxiv 2020 Dec;(): |
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Myd88tm1.1Defr | MGI:4421295 | Targeted | Null/knockout | MGI:6272304 | behavior/neurological hematopoietic system immune system nervous system mortality/aging | MP:0005386 MP:0005397 MP:0005387 MP:0003631 MP:0010768 | Butchi N, J Virol 2015 Sep 15;89(18):9299-312 Khan S, bioRxiv 2021 Mar;(): Alameh MG, Immunity 2021 Dec 14;54(12):2877-2892.e7 | J:224849 J:303202 J:337329 | Infection|Mouse_Hepatitis_virus|Pathology Infection|SARS-CoV-2_virus SARS-CoV-2_virus|Vaccine | Myd88tm1.1DefrTargeted |
MGI:6272304 | behavior/neurological hematopoietic system immune system nervous system mortality/aging |
Butchi N, J Virol 2015 Sep 15;89(18):9299-312 Khan S, bioRxiv 2021 Mar;(): Alameh MG, Immunity 2021 Dec 14;54(12):2877-2892.e7 |
||
Myd88tm1Aki | MGI:2385681 | Targeted | Null/knockout | MGI:3694811 MGI:3577712 | Coronavirus infectious disease | DOID:0080599 | digestive/alimentary system endocrine/exocrine glands hematopoietic system homeostasis/metabolism immune system liver/biliary system respiratory system vision/eye neoplasm cardiovascular system cellular hearing/vestibular/ear nervous system renal/urinary system mortality/aging | MP:0005381 MP:0005379 MP:0005397 MP:0005376 MP:0005387 MP:0005370 MP:0005388 MP:0005391 MP:0002006 MP:0005385 MP:0005384 MP:0005377 MP:0003631 MP:0005367 MP:0010768 | Cervantes-Barragan L, Blood 2007 Feb 1;109(3):1131-7 Imai Y, Cell 2008 Apr 18;133(2):235-49 Sheahan T, PLoS Pathog 2008 Dec;4(12):e1000240 Zhao J, Proc Natl Acad Sci U S A 2014 Apr 1;111(13):4970-5 Zheng M, J Biol Chem 2020 Oct 9;295(41):14040-14052 Salvi V, bioRxiv 2021 Apr;(): Zheng M, Nat Immunol 2021 Jul;22(7):829-838 Salvi V, JCI Insight 2021 Sep 22;6(18):e150542 Nagai M, mBio 2021 Aug 31;12(4):e0159821 | J:144400 J:145306 J:162707 J:207380 J:298138 J:304651 J:308903 J:313336 J:313440 | Infection|Mouse_Hepatitis_virus|SARS-CoV_virus SARS-CoV_virus Pathology|SARS-CoV-MA_virus MERS-CoV_virus Mouse_Hepatitis_virus Infection|SARS-CoV-2_virus Pathology|SARS-CoV-2_virus SARS-CoV-2_virus SARS-CoV-2_virus|Vaccine | Myd88tm1AkiTargeted |
MGI:3694811 MGI:3577712 | digestive/alimentary system endocrine/exocrine glands hematopoietic system homeostasis/metabolism immune system liver/biliary system respiratory system vision/eye neoplasm cardiovascular system cellular hearing/vestibular/ear nervous system renal/urinary system mortality/aging Coronavirus infectious disease |
Cervantes-Barragan L, Blood 2007 Feb 1;109(3):1131-7 Imai Y, Cell 2008 Apr 18;133(2):235-49 Sheahan T, PLoS Pathog 2008 Dec;4(12):e1000240 Zhao J, Proc Natl Acad Sci U S A 2014 Apr 1;111(13):4970-5 Zheng M, J Biol Chem 2020 Oct 9;295(41):14040-14052 Salvi V, bioRxiv 2021 Apr;(): Zheng M, Nat Immunol 2021 Jul;22(7):829-838 Salvi V, JCI Insight 2021 Sep 22;6(18):e150542 Nagai M, mBio 2021 Aug 31;12(4):e0159821 |
Ncf1m1J | MGI:2661962 | Spontaneous | MGI:2661972 | chronic granulomatous disease | DOID:3265 | hematopoietic system immune system | MP:0005397 MP:0005387 | Imai Y, Cell 2008 Apr 18;133(2):235-49 | J:145306 | SARS-CoV_virus | Ncf1m1JSpontaneous |
MGI:2661972 | hematopoietic system immune system chronic granulomatous disease |
Imai Y, Cell 2008 Apr 18;133(2):235-49 |
|
Nfe2l2tm1Ywk | MGI:2385926 | Targeted | Null/knockout | Qu Y, Microbiol Spectr 2023 Jun 15;11(3):e0037823 | J:357765 | Gene|Variant|VOC_B.1.1.529_Omicron | Nfe2l2tm1YwkTargeted |
Qu Y, Microbiol Spectr 2023 Jun 15;11(3):e0037823 |
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Nlrc4tm1Vmd | MGI:3046934 | Targeted | Null/knockout | Zheng M, J Biol Chem 2020 Oct 9;295(41):14040-14052 | J:298138 | Mouse_Hepatitis_virus | Nlrc4tm1VmdTargeted |
Zheng M, J Biol Chem 2020 Oct 9;295(41):14040-14052 |
|||||||
Nlrp3tm1Bhk | MGI:5465108 | Targeted | Null/knockout | Wu J, Immunity 2021 Nov 9;54(11):2632-2649.e6 Yalcinkaya M, Sci Rep 2021 Dec 24;11(1):24432 Duhalde Vega M, Sci Adv 2022 Sep 23;8(38):eabn6545 | J:323769 J:329139 J:331762 | Gene|Pathology Pathology|SARS-CoV-2_virus Mouse_Hepatitis_virus | Nlrp3tm1BhkTargeted |
Wu J, Immunity 2021 Nov 9;54(11):2632-2649.e6 Yalcinkaya M, Sci Rep 2021 Dec 24;11(1):24432 Duhalde Vega M, Sci Adv 2022 Sep 23;8(38):eabn6545 |
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Nlrp3tm1Flv | MGI:3686871 | Targeted | Null/knockout | Zheng M, J Biol Chem 2020 Oct 9;295(41):14040-14052 Zheng M, Nat Immunol 2021 Jul;22(7):829-838 | J:298138 J:308903 | Mouse_Hepatitis_virus Pathology|SARS-CoV-2_virus | Nlrp3tm1FlvTargeted |
Zheng M, J Biol Chem 2020 Oct 9;295(41):14040-14052 Zheng M, Nat Immunol 2021 Jul;22(7):829-838 |
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Nlrp3tm1Tsc | MGI:3721141 | Targeted | Null/knockout|Reporter | Zeng J, EBioMedicine 2021 Dec 31;75():103803 | J:319443 | Pathology|SARS-CoV-2_virus | Nlrp3tm1TscTargeted |
Zeng J, EBioMedicine 2021 Dec 31;75():103803 |
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Nlrp3tm1Vmd | MGI:3622094 | Targeted | Null/knockout | Yang J, Nature 2020 Jul 29;(): | J:292665 | SARS-CoV-2_virus|Vaccine | Nlrp3tm1VmdTargeted |
Yang J, Nature 2020 Jul 29;(): |
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Nos2tm1Lau | MGI:1857228 | Targeted | Null/knockout | Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 | J:296686 | Pathology|SARS-CoV-2_virus|Treatment | Nos2tm1LauTargeted |
Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 |
|||||||
Notch1tm2Rko | MGI:3044585 | Targeted | Conditional ready|No functional change | Harb H, Immunity 2021 Apr 22;(): | J:347529 | Infection | Notch1tm2RkoTargeted |
Harb H, Immunity 2021 Apr 22;(): |
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Notch2tm3Grid | MGI:3617328 | Targeted | Conditional ready|No functional change | Harb H, Immunity 2021 Apr 22;(): | J:347529 | Infection | Notch2tm3GridTargeted |
Harb H, Immunity 2021 Apr 22;(): |
|||||||
Notch3em1Tch | MGI:7624470 | Endonuclease-mediated | Conditional ready | Harb H, Immunity 2021 Apr 22;(): | J:347529 | Infection | Notch3em1TchEndonuclease-mediated |
Harb H, Immunity 2021 Apr 22;(): |
|||||||
Notch4tm1c(NCOM)Mfgc | MGI:6316296 | Targeted | Conditional ready | Harb H, Immunity 2021 Apr 22;(): | J:347529 | Infection | Notch4tm1c(NCOM)MfgcTargeted |
Harb H, Immunity 2021 Apr 22;(): |
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Omptm3Mom | MGI:3692201 | Targeted | Null/knockout|Reporter | Brechbuhl J, Commun Biol 2021 Jul 15;4(1):880 | J:319436 | Gene | Omptm3MomTargeted |
||||||||
Parp12tm1.1(KOMP)Vlcg | MGI:5548746 | Targeted | Null/knockout|Reporter | Kerr CM, J Virol 2023 Sep 28;97(9):e0088523 | J:340885 | Gene|Infection|Mouse_Hepatitis_virus | Parp12tm1.1(KOMP)VlcgTargeted |
Kerr CM, J Virol 2023 Sep 28;97(9):e0088523 |
|||||||
Pdgfbtm3.1Cbet | MGI:2670574 | Targeted | Null/knockout | He L, bioRxiv 2020;(): | J:295372 | Infection|SARS-CoV-2_virus | Pdgfbtm3.1CbetTargeted |
He L, bioRxiv 2020;(): |
|||||||
Pj1BALB/cHeA | MGI:3613181 | QTL | Kyuwa S, Microb Pathog 1992 Feb;12(2):95-104 | J:1357 | Mouse_Hepatitis_virus | Pj1BALB/cHeAQTL |
Kyuwa S, Microb Pathog 1992 Feb;12(2):95-104 |
||||||||
Pj1STS/A | MGI:3613177 | QTL | Kyuwa S, Microb Pathog 1992 Feb;12(2):95-104 | J:1357 | Mouse_Hepatitis_virus | Pj1STS/AQTL |
Kyuwa S, Microb Pathog 1992 Feb;12(2):95-104 |
||||||||
Pla2g2dtm1.1Mhg | MGI:5517549 | Targeted | Null/knockout | MGI:5520923 | cellular hematopoietic system homeostasis/metabolism immune system mortality/aging | MP:0005384 MP:0005397 MP:0005376 MP:0005387 MP:0010768 | Vijay R, J Exp Med 2015 Oct 19;212(11):1851-68 Zheng J, J Clin Invest 2021 Jun 1;131(11): | J:229035 J:311966 | Infection|SARS-CoV-MA_virus Comorbidity|MERS-CoV_virus | Pla2g2dtm1.1MhgTargeted |
MGI:5520923 | cellular hematopoietic system homeostasis/metabolism immune system mortality/aging |
Vijay R, J Exp Med 2015 Oct 19;212(11):1851-68 Zheng J, J Clin Invest 2021 Jun 1;131(11): |
||
Plattm1Mlg | MGI:1857288 | Targeted | Null/knockout | MGI:6433845 | immune system mortality/aging | MP:0005387 MP:0010768 | Gralinski LE, mBio 2013 Aug 6;4(4): | J:288556 | Infection|Pathology|SARS-CoV-MA_virus | Plattm1MlgTargeted |
MGI:6433845 | immune system mortality/aging |
Gralinski LE, mBio 2013 Aug 6;4(4): |
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Ppp1r14ctm1Uhl | MGI:4450989 | Targeted | Null/knockout | MGI:6433773 | Coronavirus infectious disease | DOID:0080599 | immune system | MP:0005387 | McDermott JE, BMC Syst Biol 2016 Sep 23;10(1):93 | J:288523 | Pathology|SARS-CoV-MA_virus | Ppp1r14ctm1UhlTargeted |
MGI:6433773 | immune system Coronavirus infectious disease |
McDermott JE, BMC Syst Biol 2016 Sep 23;10(1):93 |
Prkdcem26Gpt | MGI:5827572 | Endonuclease-mediated | Not Specified | Hu Z, bioRxiv 2021 Nov;(): | J:313461 | Infection|SARS-CoV-2_virus | Prkdcem26GptEndonuclease-mediated |
Hu Z, bioRxiv 2021 Nov;(): |
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Prkdcscid | MGI:1857113 | Spontaneous | Graham RL, Nat Med 2012 Dec;18(12):1820-6 Halwe S, bioRxiv 2021 Jun;(): Abdelnabi R, J Virol 2022 Aug 24;96(16):e0075822 Pewe L, J Virol 1997 Oct;71(10):7640-7 | J:286309 J:308648 J:331764 J:42952 | SARS-CoV_virus|Vaccine SARS-CoV-2_virus|Treatment|VOC_B.1.1.7_Alpha|VOC_B.1.351_Beta Treatment|VOC_B.1.351_Beta Mouse_Hepatitis_virus | PrkdcscidSpontaneous |
Graham RL, Nat Med 2012 Dec;18(12):1820-6 Halwe S, bioRxiv 2021 Jun;(): Abdelnabi R, J Virol 2022 Aug 24;96(16):e0075822 Pewe L, J Virol 1997 Oct;71(10):7640-7 |
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Ptgdrtm1.1Brey | MGI:6802150 | Targeted | Conditional ready|No functional change | Verma AK, mBio 2021 Oct 26;12(5):e0196921 | J:313438 | Mouse_Hepatitis_virus | Ptgdrtm1.1BreyTargeted |
Verma AK, mBio 2021 Oct 26;12(5):e0196921 |
|||||||
Ptgdrtm1Sna | MGI:2386956 | Targeted | Null/knockout | MGI:3057193 | hematopoietic system immune system nervous system respiratory system mortality/aging | MP:0005397 MP:0005387 MP:0003631 MP:0005388 MP:0010768 | Vijay R, Proc Natl Acad Sci U S A 2017 Jul 03;114(27):E5444-E5453 Verma AK, mBio 2021 Oct 26;12(5):e0196921 | J:243958 J:313438 | Mouse_Hepatitis_virus | Ptgdrtm1SnaTargeted |
MGI:3057193 | hematopoietic system immune system nervous system respiratory system mortality/aging |
Vijay R, Proc Natl Acad Sci U S A 2017 Jul 03;114(27):E5444-E5453 Verma AK, mBio 2021 Oct 26;12(5):e0196921 |
||
Ptges2tm1Bhk | MGI:3620552 | Targeted | Null/knockout | McDermott JE, BMC Syst Biol 2016 Sep 23;10(1):93 | J:288523 | Pathology|SARS-CoV-MA_virus | Ptges2tm1BhkTargeted |
McDermott JE, BMC Syst Biol 2016 Sep 23;10(1):93 |
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Ptpn2tm1c(EUCOMM)Wtsi | MGI:5902694 | Targeted | Conditional ready | Spalinger MR, bioRxiv 2020 Dec 9;(): | J:300213 | SARS-CoV-2_virus|Treatment | Ptpn2tm1c(EUCOMM)WtsiTargeted |
Spalinger MR, bioRxiv 2020 Dec 9;(): |
|||||||
Ptpn2tm1Mtr | MGI:3044910 | Targeted | Null/knockout | Spalinger MR, bioRxiv 2020 Dec 9;(): | J:300213 | SARS-CoV-2_virus|Treatment | Ptpn2tm1MtrTargeted |
Spalinger MR, bioRxiv 2020 Dec 9;(): |
|||||||
Ptx3tm1Zuk | MGI:2670952 | Targeted | Null/knockout | MGI:2670955 | endocrine/exocrine glands immune system reproductive system | MP:0005379 MP:0005387 MP:0005389 | Han B, Lab Invest 2012 Sep;92(9):1285-96 | J:188421 | Mouse_Hepatitis_virus | Ptx3tm1ZukTargeted |
MGI:2670955 | endocrine/exocrine glands immune system reproductive system |
Han B, Lab Invest 2012 Sep;92(9):1285-96 |
||
Pycardtm1Nnz | MGI:3771030 | Targeted | Null/knockout | Zheng M, J Biol Chem 2020 Oct 9;295(41):14040-14052 | J:298138 | Mouse_Hepatitis_virus | Pycardtm1NnzTargeted |
Zheng M, J Biol Chem 2020 Oct 9;295(41):14040-14052 |
|||||||
Rag1tm1Mom | MGI:1857241 | Targeted | Null/knockout | Chen BP, J Immunol 2001 Oct 15;167(8):4585-92 Templeton SP, J Neuroimmunol 2008 Feb;194(1-2):18-26 Graham RL, Nat Med 2012 Dec;18(12):1820-6 Channappanavar R, J Infect Dis 2015 Dec 15;212(12):1894-903 Hassan AO, Cell 2020 Jun 10;(): Johansen MD, Mucosal Immunol 2020 Aug 20;(): Halwe S, bioRxiv 2021 Jun;(): Mao T, bioRxiv 2021 Jun;(): Israelow B, bioRxiv 2021 May;(): Israelow B, Sci Immunol 2021 Oct 15;6(64):eabl4509 Ngo VL, Cell Host Microbe 2024 Jan 23;(): Glass WG, J Immunol 2004 Sep 15;173(6):4030-9 | J:106738 J:131907 J:286309 J:287959 J:290258 J:295350 J:308648 J:308656 J:308733 J:331753 J:345954 J:92752 | Mouse_Hepatitis_virus|Pathology Mouse_Hepatitis_virus SARS-CoV_virus|Vaccine MERS-CoV_virus|Treatment Infection|SARS-CoV-2_virus|Treatment MERS-CoV-MA_virus|MERS-CoV_virus|SARS-CoV-2-MA_virus|SARS-CoV-2_virus|SARS-CoV-MA_virus|SARS-CoV_virus SARS-CoV-2_virus|Treatment|VOC_B.1.1.7_Alpha|VOC_B.1.351_Beta Treatment|VOC_B.1.1.7_Alpha|VOC_B.1.351_Beta|VOC_P.1_Gamma Infection|SARS-CoV-2_virus Infection|MERS-CoV-MA_virus Infection|SARS-CoV_virus | Rag1tm1MomTargeted |
Chen BP, J Immunol 2001 Oct 15;167(8):4585-92 Templeton SP, J Neuroimmunol 2008 Feb;194(1-2):18-26 Graham RL, Nat Med 2012 Dec;18(12):1820-6 Channappanavar R, J Infect Dis 2015 Dec 15;212(12):1894-903 Hassan AO, Cell 2020 Jun 10;(): Johansen MD, Mucosal Immunol 2020 Aug 20;(): Halwe S, bioRxiv 2021 Jun;(): Mao T, bioRxiv 2021 Jun;(): Israelow B, bioRxiv 2021 May;(): Israelow B, Sci Immunol 2021 Oct 15;6(64):eabl4509 Ngo VL, Cell Host Microbe 2024 Jan 23;(): Glass WG, J Immunol 2004 Sep 15;173(6):4030-9 |
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Rag2tm1.1Flv | MGI:4887836 | Targeted | Null/knockout | Mao T, bioRxiv 2021 Jun;(): Sefik E, bioRxiv 2021;(): | J:308656 J:311907 | Treatment|VOC_B.1.1.7_Alpha|VOC_B.1.351_Beta|VOC_P.1_Gamma SARS-CoV-2_virus | Rag2tm1.1FlvTargeted |
Mao T, bioRxiv 2021 Jun;(): Sefik E, bioRxiv 2021;(): |
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Rapgef3tm1.1Chen | MGI:5559594 | Targeted | Null/knockout | Xiao J, J Biol Chem 2021 Oct 19;():101315 | J:313334 | Pathology | Rapgef3tm1.1ChenTargeted |
||||||||
Rbpjtm1Hon | MGI:3583755 | Targeted | Conditional ready|No functional change | Harb H, Immunity 2021 Apr 22;(): | J:347529 | Infection | Rbpjtm1HonTargeted |
Harb H, Immunity 2021 Apr 22;(): |
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Ripk3tm1.1Vmd | MGI:7256694 | Targeted | Null/knockout | Wenzel J, Nat Neurosci 2021 Nov;24(11):1522-1533 | J:323957 | Pathology|SARS-CoV-2_virus|VOC_B.1.351_Beta | Ripk3tm1.1VmdTargeted |
Wenzel J, Nat Neurosci 2021 Nov;24(11):1522-1533 |
|||||||
Ripk3tm1Vmd | MGI:3028853 | Targeted | Null/knockout | Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 Zheng M, J Biol Chem 2020 Oct 9;295(41):14040-14052 | J:296686 J:298138 | Pathology|SARS-CoV-2_virus|Treatment Mouse_Hepatitis_virus | Ripk3tm1VmdTargeted |
Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 Zheng M, J Biol Chem 2020 Oct 9;295(41):14040-14052 |
|||||||
Rnaseltm1Slvm | MGI:2182763 | Targeted | Null/knockout | Zhang R, Proc Natl Acad Sci U S A 2013 Aug 6;110(32):13114-9 Goldstein SA, J Virol 2017 Mar 01;91(5): Kindler E, PLoS Pathog 2017 Feb;13(2):e1006195 Thornbrough JM, mBio 2016 Mar 29;7(2):e00258 Birdwell LD, J Virol 2016 Jan 6;90(6):3160-72 Zhao L, J Virol 2013 Aug;87(15):8408-18 | J:200706 J:239306 J:291588 J:292006 J:318622 J:346257 | Mouse_Hepatitis_virus Infection|Mouse_Hepatitis_virus HCoV-229E_virus|Mouse_Hepatitis_virus MERS-CoV_virus|Mouse_Hepatitis_virus | Rnaseltm1SlvmTargeted |
Zhang R, Proc Natl Acad Sci U S A 2013 Aug 6;110(32):13114-9 Goldstein SA, J Virol 2017 Mar 01;91(5): Kindler E, PLoS Pathog 2017 Feb;13(2):e1006195 Thornbrough JM, mBio 2016 Mar 29;7(2):e00258 Birdwell LD, J Virol 2016 Jan 6;90(6):3160-72 Zhao L, J Virol 2013 Aug;87(15):8408-18 |
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Rnh1tm2.1Rall | MGI:7407148 | Targeted | Conditional ready | Bombaci G, Life Sci Alliance 2022 Jun;5(6):e202101226 | J:331827 | SARS-CoV-2_virus | Rnh1tm2.1RallTargeted |
Bombaci G, Life Sci Alliance 2022 Jun;5(6):e202101226 |
|||||||
Samhd1tm1d(EUCOMM)Wtsi | MGI:5551758 | Targeted | Null/knockout | Tada T, Proc Natl Acad Sci U S A 2023 Jun 6;120(23):e2303509120 | J:338414 | SARS-CoV-2_virus|Treatment|VOC_B.1.1.529_Omicron | Samhd1tm1d(EUCOMM)WtsiTargeted |
Tada T, Proc Natl Acad Sci U S A 2023 Jun 6;120(23):e2303509120 |
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Serpine1tm1Mlg | MGI:1857287 | Targeted | Null/knockout | MGI:3690223 | Coronavirus infectious disease | DOID:0080599 | cardiovascular system homeostasis/metabolism immune system liver/biliary system respiratory system mortality/aging | MP:0005385 MP:0005376 MP:0005387 MP:0005370 MP:0005388 MP:0010768 | Gralinski LE, mBio 2013 Aug 6;4(4): | J:288556 | Infection|Pathology|SARS-CoV-MA_virus | Serpine1tm1MlgTargeted |
MGI:3690223 | cardiovascular system homeostasis/metabolism immune system liver/biliary system respiratory system mortality/aging Coronavirus infectious disease |
Gralinski LE, mBio 2013 Aug 6;4(4): |
Setdb2tm1c(KOMP)Wtsi | MGI:5816257 | Targeted | Conditional ready | Melvin WJ, Proc Natl Acad Sci U S A 2021 Sep 21;118(38):e2101071118 | J:311033 | Comorbidity|Gene|Mouse_Hepatitis_virus | Setdb2tm1c(KOMP)WtsiTargeted |
Melvin WJ, Proc Natl Acad Sci U S A 2021 Sep 21;118(38):e2101071118 |
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Sftpctm1(cre/ERT2)Blh | MGI:5305340 | Targeted | Inducible|Recombinase | Tang AT, bioRxiv 2021 Dec;(): Tang AT, PLoS Biol 2023 Feb;21(2):e3001989 | J:315719 J:337814 | Pathology|SARS-CoV-2_virus Pathology|SARS-CoV-2_virus|VOC_B.1.1.529_Omicron | Sftpctm1(cre/ERT2)BlhTargeted |
Tang AT, bioRxiv 2021 Dec;(): Tang AT, PLoS Biol 2023 Feb;21(2):e3001989 |
|||||||
Shhtm1(EGFP/cre)Cjt | MGI:3053959 | Targeted | Null/knockout|Recombinase | Tang AT, bioRxiv 2021 Dec;(): Tang AT, PLoS Biol 2023 Feb;21(2):e3001989 | J:315719 J:337814 | Pathology|SARS-CoV-2_virus Pathology|SARS-CoV-2_virus|VOC_B.1.1.529_Omicron | Shhtm1(EGFP/cre)CjtTargeted |
Tang AT, bioRxiv 2021 Dec;(): Tang AT, PLoS Biol 2023 Feb;21(2):e3001989 |
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Shhtm2(cre/ERT2)Cjt | MGI:3053960 | Targeted | Inducible|Recombinase | Anand G, bioRxiv 2020 Dec;(): | J:298270 | Pathology|SARS-CoV-2_virus | Shhtm2(cre/ERT2)CjtTargeted |
Anand G, bioRxiv 2020 Dec;(): |
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Sirpatm1Nog | MGI:2388979 | Targeted | Null/knockout | Wenzek C, iScience 2022 Dec 22;25(12):105540 | J:331693 | SARS-CoV-2_virus | Sirpatm1NogTargeted |
Wenzek C, iScience 2022 Dec 22;25(12):105540 |
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Smad3tm1Cxd | MGI:1857695 | Targeted | Null/knockout | Wang W, Adv Sci (Weinh) 2022 Jan;9(3):e2103248 | J:333753 | Pathology|SARS-CoV-2_virus | Smad3tm1CxdTargeted |
Wang W, Adv Sci (Weinh) 2022 Jan;9(3):e2103248 |
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Srydl1Rlb | MGI:1857786 | Spontaneous | Ensor CM, bioRxiv 2021-09;(): | J:310122 | SARS-CoV-2_virus | Srydl1RlbSpontaneous |
Ensor CM, bioRxiv 2021-09;(): |
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Stat1tm1Dlv | MGI:1930947 | Targeted | Null/knockout | MGI:3806318 MGI:6403902 MGI:6403905 | Coronavirus infectious disease | DOID:0080599 | hematopoietic system homeostasis/metabolism immune system vision/eye cardiovascular system digestive/alimentary system respiratory system | MP:0005397 MP:0005376 MP:0005387 MP:0005391 MP:0005385 MP:0005381 MP:0005388 | Lassnig C, Transgenic Res 2005 Dec;14(6):803-6 Venkataraman T, J Virol 2017 Jun 15;91(12): Page C, J Virol 2012 Dec;86(24):13334-49 Hassan AO, Cell 2020 Jun 10;(): Sun J, Cell 2020 Jun 10;(): Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 Ngo VL, Cell Host Microbe 2024 Jan 23;(): Lassnig C, Proc Natl Acad Sci U S A 2005 Jun 7;102(23):8275-80 | J:103578 J:243599 J:286337 J:290258 J:291881 J:296686 J:345954 J:99728 | HCoV-229E_virus Pathology|SARS-CoV-MA_virus Pathology|SARS-CoV_virus Infection|SARS-CoV-2_virus|Treatment Infection|Pathology|SARS-CoV-2_virus|Treatment Pathology|SARS-CoV-2_virus|Treatment Infection|MERS-CoV-MA_virus | Stat1tm1DlvTargeted |
MGI:3806318 MGI:6403902 MGI:6403905 | hematopoietic system homeostasis/metabolism immune system vision/eye cardiovascular system digestive/alimentary system respiratory system Coronavirus infectious disease |
Lassnig C, Transgenic Res 2005 Dec;14(6):803-6 Venkataraman T, J Virol 2017 Jun 15;91(12): Page C, J Virol 2012 Dec;86(24):13334-49 Hassan AO, Cell 2020 Jun 10;(): Sun J, Cell 2020 Jun 10;(): Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 Ngo VL, Cell Host Microbe 2024 Jan 23;(): Lassnig C, Proc Natl Acad Sci U S A 2005 Jun 7;102(23):8275-80 |
Stat1tm1Mam | MGI:4821871 | Targeted | Conditional ready|No functional change | Page C, J Virol 2012 Dec;86(24):13334-49 | J:286337 | Pathology|SARS-CoV_virus | Stat1tm1MamTargeted |
Page C, J Virol 2012 Dec;86(24):13334-49 |
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Stat1tm1Rds | MGI:1861949 | Targeted | Null/knockout | MGI:3771372 | breast cancer severe acute respiratory syndrome | DOID:1612 DOID:2945 | cardiovascular system cellular digestive/alimentary system endocrine/exocrine glands hematopoietic system homeostasis/metabolism immune system integument liver/biliary system muscle nervous system respiratory system skeleton neoplasm mortality/aging | MP:0005385 MP:0005384 MP:0005381 MP:0005379 MP:0005397 MP:0005376 MP:0005387 MP:0010771 MP:0005370 MP:0005369 MP:0003631 MP:0005388 MP:0005390 MP:0002006 MP:0010768 | Zornetzer GA, J Virol 2010 Nov;84(21):11297-309 Peng X, mBio 2010 Oct 26;1(5): Frieman MB, PLoS Pathog 2010 Apr 8;6(4):e1000849 Graham RL, Nat Med 2012 Dec;18(12):1820-6 Singh A, Virol Sin 2020 Jun;35(3):290-304 Johansen MD, Mucosal Immunol 2020 Aug 20;(): | J:164586 J:276986 J:286237 J:286309 J:295349 J:295350 | Pathology|SARS-CoV-MA_virus Infection|SARS-CoV-MA_virus SARS-CoV_virus|Vaccine MERS-CoV-MA_virus|MERS-CoV_virus|SARS-CoV-2-MA_virus|SARS-CoV-2_virus|SARS-CoV_virus MERS-CoV-MA_virus|MERS-CoV_virus|SARS-CoV-2-MA_virus|SARS-CoV-2_virus|SARS-CoV-MA_virus|SARS-CoV_virus | Stat1tm1RdsTargeted |
MGI:3771372 | cardiovascular system cellular digestive/alimentary system endocrine/exocrine glands hematopoietic system homeostasis/metabolism immune system integument liver/biliary system muscle nervous system respiratory system skeleton neoplasm mortality/aging breast cancer severe acute respiratory syndrome |
Zornetzer GA, J Virol 2010 Nov;84(21):11297-309 Peng X, mBio 2010 Oct 26;1(5): Frieman MB, PLoS Pathog 2010 Apr 8;6(4):e1000849 Graham RL, Nat Med 2012 Dec;18(12):1820-6 Singh A, Virol Sin 2020 Jun;35(3):290-304 Johansen MD, Mucosal Immunol 2020 Aug 20;(): |
Stat6tm1Gru | MGI:1888385 | Targeted | Null/knockout | Page C, J Virol 2012 Dec;86(24):13334-49 | J:286337 | Pathology|SARS-CoV_virus | Stat6tm1GruTargeted |
Page C, J Virol 2012 Dec;86(24):13334-49 |
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Sting1gt | MGI:4939597 | Chemically induced (ENU) | Yang J, Nature 2020 Jul 29;(): Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 | J:292665 J:296686 | SARS-CoV-2_virus|Vaccine Pathology|SARS-CoV-2_virus|Treatment | Sting1gtChemically induced (ENU) |
Yang J, Nature 2020 Jul 29;(): Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 |
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Sting1tm1.2Camb | MGI:5639232 | Targeted | Null/knockout | Wu J, Immunity 2021 Nov 9;54(11):2632-2649.e6 | J:323769 | Gene|Pathology | Sting1tm1.2CambTargeted |
Wu J, Immunity 2021 Nov 9;54(11):2632-2649.e6 |
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Sting1tm1Gnb | MGI:3817418 | Targeted | Null/knockout | Humphries F, Sci Immunol 2021 May 18;6(59): | J:333769 | SARS-CoV-2_virus|Treatment | Sting1tm1GnbTargeted |
Humphries F, Sci Immunol 2021 May 18;6(59): |
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Tcratm1Mom | MGI:1857255 | Targeted | Null/knockout | Hilligan KL, Nat Commun 2023 Dec 12;14(1):8229 | J:343550 | Infection|SARS-CoV-2_virus|Treatment | Tcratm1MomTargeted |
Hilligan KL, Nat Commun 2023 Dec 12;14(1):8229 |
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Tcrbtm1Mom | MGI:1857256 | Targeted | Null/knockout | Dandekar AA, J Virol 2005 Aug;79(15):9388-96 | J:153339 | Mouse_Hepatitis_virus | Tcrbtm1MomTargeted |
Dandekar AA, J Virol 2005 Aug;79(15):9388-96 |
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Terctm1Rdp | MGI:1857930 | Targeted | Null/knockout | Sepe S, bioRxiv 2021 Jun;(): Sepe S, EMBO Rep 2022 Feb 3;23(2):e53658 | J:309195 J:326929 | Comorbidity|Gene Gene | Terctm1RdpTargeted |
Sepe S, bioRxiv 2021 Jun;(): |
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Terf2tm1Tdl | MGI:3619524 | Targeted | Conditional ready|No functional change | Sepe S, bioRxiv 2021 Jun;(): Sepe S, EMBO Rep 2022 Feb 3;23(2):e53658 | J:309195 J:326929 | Comorbidity|Gene Gene | Terf2tm1TdlTargeted |
Sepe S, bioRxiv 2021 Jun;(): |
|||||||
Tg(Ace2-ACE2)1Cqin | MGI:6401292 | Transgenic | Humanized sequence|Inserted expressed sequence | MGI:6402641 | COVID-19 severe acute respiratory syndrome | DOID:0080600 DOID:2945 | cardiovascular system digestive/alimentary system endocrine/exocrine glands growth/size/body homeostasis/metabolism immune system liver/biliary system nervous system renal/urinary system respiratory system | MP:0005385 MP:0005381 MP:0005379 MP:0005378 MP:0005376 MP:0005387 MP:0005370 MP:0003631 MP:0005367 MP:0005388 | Yang XH, Comp Med 2007 Oct;57(5):450-9 Bao L, Nature 2020 May 7;(): Natoli S, Eur J Neurol 2020 Apr 25;(): Bao L, J Infect Dis 2020 May 23;(): Lutz C, Hum Genomics 2020 Jun 4;14(1):20 Yang J, Nature 2020 Jul 29;(): Mullick JB, Cell Mol Bioeng 2020 Jul 27;():1-11 Leist SR, Dis Model Mech 2020 Sep 1;13(9):dmm046581 Singh A, Virol Sin 2020 Jun;35(3):290-304 Johansen MD, Mucosal Immunol 2020 Aug 20;(): Munoz-Fontela C, Nature 2020 Sep 23;(): Jia H, Nat Commun 2020 Oct 14;11(1):5165 Guo Q, Cell Host Microbe 2021 Feb 10;29(2):222-235.e4 Shang C, J Virol 2021 Nov 23;95(24):e0153721 | J:141460 J:287631 J:287925 J:288244 J:288402 J:292665 J:294026 J:295328 J:295349 J:295350 J:295351 J:296535 J:308901 J:331770 | Infection|SARS-CoV_virus Infection|Pathology|SARS-CoV-2_virus Infection|SARS-CoV-2_virus SARS-CoV-2_virus SARS-CoV-2_virus|Vaccine SARS-CoV-2_virus|SARS-CoV_virus MERS-CoV-MA_virus|MERS-CoV_virus|SARS-CoV-2-MA_virus|SARS-CoV-2_virus|SARS-CoV_virus MERS-CoV-MA_virus|MERS-CoV_virus|SARS-CoV-2-MA_virus|SARS-CoV-2_virus|SARS-CoV-MA_virus|SARS-CoV_virus SARS-CoV-2-MA_virus|SARS-CoV-2_virus|SARS-CoV_virus Pathology|SARS-CoV-2_virus SARS-CoV-2_virus|Treatment | Tg(Ace2-ACE2)1CqinTransgenic |
MGI:6402641 | cardiovascular system digestive/alimentary system endocrine/exocrine glands growth/size/body homeostasis/metabolism immune system liver/biliary system nervous system renal/urinary system respiratory system COVID-19 severe acute respiratory syndrome |
Yang XH, Comp Med 2007 Oct;57(5):450-9 Bao L, Nature 2020 May 7;(): Natoli S, Eur J Neurol 2020 Apr 25;(): Bao L, J Infect Dis 2020 May 23;(): Lutz C, Hum Genomics 2020 Jun 4;14(1):20 Yang J, Nature 2020 Jul 29;(): Mullick JB, Cell Mol Bioeng 2020 Jul 27;():1-11 Leist SR, Dis Model Mech 2020 Sep 1;13(9):dmm046581 Singh A, Virol Sin 2020 Jun;35(3):290-304 Johansen MD, Mucosal Immunol 2020 Aug 20;(): Munoz-Fontela C, Nature 2020 Sep 23;(): Jia H, Nat Commun 2020 Oct 14;11(1):5165 Guo Q, Cell Host Microbe 2021 Feb 10;29(2):222-235.e4 Shang C, J Virol 2021 Nov 23;95(24):e0153721 |
Tg(Acta2-GFP)1Pfk | MGI:5805225 | Transgenic | Inserted expressed sequence|Reporter | He L, bioRxiv 2020;(): | J:295372 | Infection|SARS-CoV-2_virus | Tg(Acta2-GFP)1PfkTransgenic |
He L, bioRxiv 2020;(): |
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Tg(ANPEP)270Mmul | MGI:5645778 | Transgenic | Inserted expressed sequence | MGI:6403902 MGI:6403906 | Coronavirus infectious disease | DOID:0080599 | cardiovascular system immune system | MP:0005385 MP:0005387 | Lassnig C, Proc Natl Acad Sci U S A 2005 Jun 7;102(23):8275-80 | J:99728 | HCoV-229E_virus | Tg(ANPEP)270MmulTransgenic |
MGI:6403902 MGI:6403906 | cardiovascular system immune system Coronavirus infectious disease |
Lassnig C, Proc Natl Acad Sci U S A 2005 Jun 7;102(23):8275-80 |
Tg(ANPEP)861Mmul | MGI:5645779 | Transgenic | Inserted expressed sequence | MGI:6403905 MGI:6403907 | Coronavirus infectious disease | DOID:0080599 | cardiovascular system digestive/alimentary system immune system respiratory system | MP:0005385 MP:0005381 MP:0005387 MP:0005388 | Lassnig C, Proc Natl Acad Sci U S A 2005 Jun 7;102(23):8275-80 | J:99728 | HCoV-229E_virus | Tg(ANPEP)861MmulTransgenic |
MGI:6403905 MGI:6403907 | cardiovascular system digestive/alimentary system immune system respiratory system Coronavirus infectious disease |
Lassnig C, Proc Natl Acad Sci U S A 2005 Jun 7;102(23):8275-80 |
Tg(ANPEP)#Mmul | MGI:5582782 | Transgenic | Inserted expressed sequence | Lassnig C, Proc Natl Acad Sci U S A 2005 Jun 7;102(23):8275-80 | J:99728 | HCoV-229E_virus | Tg(ANPEP)#MmulTransgenic |
Lassnig C, Proc Natl Acad Sci U S A 2005 Jun 7;102(23):8275-80 |
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Tg(APP695)3Dbo | MGI:2447334 | Transgenic | Humanized sequence|Inserted expressed sequence | Chen J, Transl Psychiatry 2023 Dec 16;13(1):396 | J:348471 | Gene|Infection|SARS-CoV-2_virus | Tg(APP695)3DboTransgenic |
Chen J, Transl Psychiatry 2023 Dec 16;13(1):396 |
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Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas | MGI:3693208 | Transgenic | Humanized sequence|Inserted expressed sequence | Lim KH, Front Genet 2021;12():741175 Hohsfield LA, Glia 2022 May;70(5):875-891 | J:319460 J:324342 | Gene|SARS-CoV-2_virus Mouse_Hepatitis_virus | Tg(APPSwFlLon,PSEN1*M146L*L286V)6799VasTransgenic |
Lim KH, Front Genet 2021;12():741175 Hohsfield LA, Glia 2022 May;70(5):875-891 |
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Tg(CAG-ACE2)AC22Ctkt | MGI:6402929 | Transgenic | Humanized sequence|Inserted expressed sequence | Tseng CT, J Virol 2007 Feb;81(3):1162-73 Yoshikawa N, J Virol 2009 Jun;83(11):5451-65 Lutz C, Hum Genomics 2020 Jun 4;14(1):20 | J:117824 J:148946 J:288402 | Infection|SARS-CoV_virus Pathology|SARS-CoV_virus SARS-CoV-2_virus | Tg(CAG-ACE2)AC22CtktTransgenic |
Tseng CT, J Virol 2007 Feb;81(3):1162-73 Yoshikawa N, J Virol 2009 Jun;83(11):5451-65 Lutz C, Hum Genomics 2020 Jun 4;14(1):20 |
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Tg(CAG-ACE2)AC63Ctkt | MGI:6402829 | Transgenic | Humanized sequence|Inserted expressed sequence | MGI:6402831 | immune system | MP:0005387 | Tseng CT, J Virol 2007 Feb;81(3):1162-73 Gretebeck LM, Curr Opin Virol 2015 Aug;13():123-9 Lutz C, Hum Genomics 2020 Jun 4;14(1):20 Mullick JB, Cell Mol Bioeng 2020 Jul 27;():1-11 | J:117824 J:284000 J:288402 J:294026 | Infection|SARS-CoV_virus MERS-CoV_virus|SARS-CoV_virus SARS-CoV-2_virus SARS-CoV-2_virus|SARS-CoV_virus | Tg(CAG-ACE2)AC63CtktTransgenic |
MGI:6402831 | immune system |
Tseng CT, J Virol 2007 Feb;81(3):1162-73 Gretebeck LM, Curr Opin Virol 2015 Aug;13():123-9 Lutz C, Hum Genomics 2020 Jun 4;14(1):20 Mullick JB, Cell Mol Bioeng 2020 Jul 27;():1-11 |
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Tg(CAG-ACE2)AC70Ctkt | MGI:6402828 | Transgenic | Humanized sequence|Inserted expressed sequence | MGI:6402832 | severe acute respiratory syndrome | DOID:2945 | cardiovascular system homeostasis/metabolism immune system respiratory system mortality/aging | MP:0005385 MP:0005376 MP:0005387 MP:0005388 MP:0010768 | Tseng CT, J Virol 2007 Feb;81(3):1162-73 Yoshikawa N, J Virol 2009 Jun;83(11):5451-65 Zumla A, Nat Rev Drug Discov 2016 May;15(5):327-47 Gretebeck LM, Curr Opin Virol 2015 Aug;13():123-9 Lutz C, Hum Genomics 2020 Jun 4;14(1):20 Mullick JB, Cell Mol Bioeng 2020 Jul 27;():1-11 Jia H, Nat Commun 2020 Oct 14;11(1):5165 Yuan L, Emerg Microbes Infect 2020 Dec;9(1):949-961 Ma H, bioRxiv 2021;(): | J:117824 J:148946 J:283999 J:284000 J:288402 J:294026 J:296535 J:300104 J:311906 | Infection|SARS-CoV_virus Pathology|SARS-CoV_virus MERS-CoV_virus|SARS-CoV_virus SARS-CoV-2_virus SARS-CoV-2_virus|SARS-CoV_virus MERS-CoV_virus|SARS-CoV-2_virus|SARS-CoV_virus SARS-CoV-2_virus|Treatment|VOC_B.1.1.7_Alpha|VOC_B.1.351_Beta|VOC_B.1.617.2_Delta|VOC_P.1_Gamma | Tg(CAG-ACE2)AC70CtktTransgenic |
MGI:6402832 | cardiovascular system homeostasis/metabolism immune system respiratory system mortality/aging severe acute respiratory syndrome |
Tseng CT, J Virol 2007 Feb;81(3):1162-73 Yoshikawa N, J Virol 2009 Jun;83(11):5451-65 Zumla A, Nat Rev Drug Discov 2016 May;15(5):327-47 Gretebeck LM, Curr Opin Virol 2015 Aug;13():123-9 Lutz C, Hum Genomics 2020 Jun 4;14(1):20 Mullick JB, Cell Mol Bioeng 2020 Jul 27;():1-11 Jia H, Nat Commun 2020 Oct 14;11(1):5165 Yuan L, Emerg Microbes Infect 2020 Dec;9(1):949-961 Ma H, bioRxiv 2021;(): |
Tg(CAG-ACE2)GT5-027Cyt | MGI:6711183 | Transgenic | Epitope tag|Humanized sequence|Inserted expressed sequence | Tsai C-Y, bioRxiv 2021;(): Liao HY, bioRxiv 2021 May;(): | J:305559 J:308661 | SARS-CoV-2_virus SARS-CoV-2_virus|Vaccine | Tg(CAG-ACE2)GT5-027CytTransgenic |
Tsai C-Y, bioRxiv 2021;(): Liao HY, bioRxiv 2021 May;(): |
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Tg(CAG-ACE2,-luc)1Smoc | MGI:7279190 | Transgenic | Humanized sequence|Inserted expressed sequence|Reporter | Li C, Cell 2022 Apr 14;185(8):1389-1401.e18 Li D, J Med Virol 2022 Oct;94(10):4878-4889 Yang S, J Med Virol 2022 Aug;94(8):3605-3612 | J:324335 J:339217 J:339218 | SARS-CoV-2_virus|Treatment|VOC_B.1.1.529_Omicron Infection|SARS-CoV-2_virus Pathology|SARS-CoV-2_virus|VOC_B.1.617.2_Delta | Tg(CAG-ACE2,-luc)1SmocTransgenic |
Li C, Cell 2022 Apr 14;185(8):1389-1401.e18 Li D, J Med Virol 2022 Oct;94(10):4878-4889 Yang S, J Med Virol 2022 Aug;94(8):3605-3612 |
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Tg(CAG-DPP4)4Yuzh | MGI:6402443 | Transgenic | Humanized sequence|Inserted expressed sequence | MGI:6402445 | Middle East respiratory syndrome | DOID:0080642 | behavior/neurological cardiovascular system hematopoietic system homeostasis/metabolism immune system liver/biliary system nervous system renal/urinary system respiratory system mortality/aging | MP:0005386 MP:0005385 MP:0005397 MP:0005376 MP:0005387 MP:0005370 MP:0003631 MP:0005367 MP:0005388 MP:0010768 | Zhao G, PLoS One 2015;10(12):e0145561 Jiang Y, Viruses 2019 Jan 9;11(1): Singh A, Virol Sin 2020 Jun;35(3):290-304 Tai W, Virology 2016 Dec;499():375-382 | J:286175 J:295108 J:295349 J:331809 | Infection|MERS-CoV_virus MERS-CoV_virus MERS-CoV-MA_virus|MERS-CoV_virus|SARS-CoV-2-MA_virus|SARS-CoV-2_virus|SARS-CoV_virus MERS-CoV_virus|Treatment | Tg(CAG-DPP4)4YuzhTransgenic |
MGI:6402445 | behavior/neurological cardiovascular system hematopoietic system homeostasis/metabolism immune system liver/biliary system nervous system renal/urinary system respiratory system mortality/aging Middle East respiratory syndrome |
Zhao G, PLoS One 2015;10(12):e0145561 Jiang Y, Viruses 2019 Jan 9;11(1): Singh A, Virol Sin 2020 Jun;35(3):290-304 Tai W, Virology 2016 Dec;499():375-382 |
Tg(CAG-DPP4)52Ctkt | MGI:6402051 | Transgenic | Humanized sequence|Inserted expressed sequence | MGI:6402055 | Middle East respiratory syndrome | DOID:0080642 | growth/size/body hematopoietic system immune system nervous system respiratory system mortality/aging | MP:0005378 MP:0005397 MP:0005387 MP:0003631 MP:0005388 MP:0010768 | Tao X, J Virol 2015;90(1):57-67 Agrawal AS, J Virol 2015 Apr;89(7):3659-70 Agrawal AS, Sci Rep 2016 Aug 19;6():31629 Gretebeck LM, Curr Opin Virol 2015 Aug;13():123-9 Leist SR, Methods Mol Biol 2020;2099():137-159 Algaissi A, J Infect Dis 2019 Feb 15;219(5):829-835 Hao XY, Animal Model Exp Med 2019 Dec;2(4):269-281 Natoli S, Eur J Neurol 2020 Apr 25;(): Choi JH, PLoS One 2020;15(5):e0232757 Agrawal AS, Hum Vaccin Immunother 2016 Sep;12(9):2351-6 Singh A, Virol Sin 2020 Jun;35(3):290-304 Johansen MD, Mucosal Immunol 2020 Aug 20;(): Yuan L, Emerg Microbes Infect 2020 Dec;9(1):949-961 | J:227925 J:258199 J:266753 J:284000 J:285962 J:286197 J:286454 J:287925 J:288262 J:291895 J:295349 J:295350 J:300104 | Infection|MERS-CoV_virus|Vaccine Infection|MERS-CoV_virus MERS-CoV_virus|Treatment MERS-CoV_virus|SARS-CoV_virus MERS-CoV_virus Infection|MERS-CoV_virus|Pathology MERS-CoV_virus|Pathology Infection|SARS-CoV-2_virus MERS-CoV_virus|Vaccine MERS-CoV-MA_virus|MERS-CoV_virus|SARS-CoV-2-MA_virus|SARS-CoV-2_virus|SARS-CoV_virus MERS-CoV-MA_virus|MERS-CoV_virus|SARS-CoV-2-MA_virus|SARS-CoV-2_virus|SARS-CoV-MA_virus|SARS-CoV_virus MERS-CoV_virus|SARS-CoV-2_virus|SARS-CoV_virus | Tg(CAG-DPP4)52CtktTransgenic |
MGI:6402055 | growth/size/body hematopoietic system immune system nervous system respiratory system mortality/aging Middle East respiratory syndrome |
Tao X, J Virol 2015;90(1):57-67 Agrawal AS, J Virol 2015 Apr;89(7):3659-70 Agrawal AS, Sci Rep 2016 Aug 19;6():31629 Gretebeck LM, Curr Opin Virol 2015 Aug;13():123-9 Leist SR, Methods Mol Biol 2020;2099():137-159 Algaissi A, J Infect Dis 2019 Feb 15;219(5):829-835 Hao XY, Animal Model Exp Med 2019 Dec;2(4):269-281 Natoli S, Eur J Neurol 2020 Apr 25;(): Choi JH, PLoS One 2020;15(5):e0232757 Agrawal AS, Hum Vaccin Immunother 2016 Sep;12(9):2351-6 Singh A, Virol Sin 2020 Jun;35(3):290-304 Johansen MD, Mucosal Immunol 2020 Aug 20;(): Yuan L, Emerg Microbes Infect 2020 Dec;9(1):949-961 |
Tg(CAG-EGFP/Map1lc3b)53Nmz | MGI:3759813 | Transgenic | Inserted expressed sequence|Reporter | Zhu H, FASEB J 2023 May;37(5):e22919 | J:341982 | Pathology|SARS-CoV-2_virus | Tg(CAG-EGFP/Map1lc3b)53NmzTransgenic |
Zhu H, FASEB J 2023 May;37(5):e22919 |
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Tg(CAG-OVAL)916Jen | MGI:3050829 | Transgenic | Inserted expressed sequence | Khanolkar A, J Immunol 2010 Jul 15;185(2):1132-41 | J:161935 | Mouse_Hepatitis_virus|Pathology | Tg(CAG-OVAL)916JenTransgenic |
Khanolkar A, J Immunol 2010 Jul 15;185(2):1132-41 |
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Tg(CAG-Serpine1)1Dgi | MGI:3763900 | Transgenic | Inserted expressed sequence | Jain KG, Am J Physiol Lung Cell Mol Physiol 2022 Nov 1;323(5):L515-L524 | J:329972 | Gene | Tg(CAG-Serpine1)1DgiTransgenic |
Jain KG, Am J Physiol Lung Cell Mol Physiol 2022 Nov 1;323(5):L515-L524 |
|||||||
Tg(CD207-Dta)312Dhka | MGI:3762048 | Transgenic | Inserted expressed sequence | Ndeupen S, bioRxiv 2021 Aug;(): | J:308580 | SARS-CoV-2_virus|Vaccine | Tg(CD207-Dta)312DhkaTransgenic |
Ndeupen S, bioRxiv 2021 Aug;(): |
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Tg(CD46)373Zbz | MGI:6501992 | Transgenic | Humanized sequence|Inserted expressed sequence | Horner C, Proc Natl Acad Sci U S A 2020 Dec 22;117(51):32657-32666 Malczyk AH, J Virol 2015 Nov;89(22):11654-67 | J:300105 J:312515 | SARS-CoV-2_virus|Vaccine MERS-CoV_virus|Vaccine | Tg(CD46)373ZbzTransgenic |
Horner C, Proc Natl Acad Sci U S A 2020 Dec 22;117(51):32657-32666 Malczyk AH, J Virol 2015 Nov;89(22):11654-67 |
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Tg(Cd4-CD4)2362Litt | MGI:3702083 | Transgenic | Humanized sequence|Inserted expressed sequence | Brentville VA, bioRxiv 2021 Jun;(): | J:308658 | SARS-CoV-2_virus|Vaccine | Tg(Cd4-CD4)2362LittTransgenic |
Brentville VA, bioRxiv 2021 Jun;(): |
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Tg(DPP4)2Nnag | MGI:6403115 | Transgenic | Humanized sequence|Inserted expressed sequence | MGI:6403636 MGI:6403118 | Middle East respiratory syndrome | DOID:0080642 | immune system homeostasis/metabolism respiratory system | MP:0005387 MP:0005376 MP:0005388 | Iwata-Yoshikawa N, J Virol 2019 Mar 15;93(6): Hao XY, Animal Model Exp Med 2019 Dec;2(4):269-281 Singh A, Virol Sin 2020 Jun;35(3):290-304 Yuan L, Emerg Microbes Infect 2020 Dec;9(1):949-961 | J:283077 J:286321 J:286454 J:295349 J:300104 | MERS-CoV-MA_virus|MERS-CoV_virus|Pathology Infection|MERS-CoV_virus MERS-CoV_virus|Pathology MERS-CoV-MA_virus|MERS-CoV_virus|SARS-CoV-2-MA_virus|SARS-CoV-2_virus|SARS-CoV_virus MERS-CoV_virus|SARS-CoV-2_virus|SARS-CoV_virus | Tg(DPP4)2NnagTransgenic |
MGI:6403636 MGI:6403118 | immune system homeostasis/metabolism respiratory system Middle East respiratory syndrome |
Iwata-Yoshikawa N, J Virol 2019 Mar 15;93(6): Iwata-Yoshikawa N, J Virol 2019 Mar 15;93(6): Hao XY, Animal Model Exp Med 2019 Dec;2(4):269-281 Singh A, Virol Sin 2020 Jun;35(3):290-304 Yuan L, Emerg Microbes Infect 2020 Dec;9(1):949-961 |
Tg(FCGRT)32Dcr | MGI:4944199 | Transgenic | Humanized sequence|Inserted expressed sequence | Halwe S, bioRxiv 2021 Jun;(): | J:308648 | SARS-CoV-2_virus|Treatment|VOC_B.1.1.7_Alpha|VOC_B.1.351_Beta | Tg(FCGRT)32DcrTransgenic |
Halwe S, bioRxiv 2021 Jun;(): |
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Tg(FOXJ1-ACE2)1Rba | MGI:6415223 | Transgenic | Inserted expressed sequence | MGI:6415340 | Coronavirus infectious disease COVID-19 severe acute respiratory syndrome | DOID:0080599 DOID:0080600 DOID:2945 | cardiovascular system hematopoietic system homeostasis/metabolism immune system muscle respiratory system mortality/aging | MP:0005385 MP:0005397 MP:0005376 MP:0005387 MP:0005369 MP:0005388 MP:0010768 | Menachery VD, Proc Natl Acad Sci U S A 2016 Mar 15;113(11):3048-53 Jiang RD, Cell 2020 May 21;(): Lutz C, Hum Genomics 2020 Jun 4;14(1):20 Dinnon KH 3rd, Nature 2020 Aug 27;(): Leist SR, Dis Model Mech 2020 Sep 1;13(9):dmm046581 Singh A, Virol Sin 2020 Jun;35(3):290-304 Johansen MD, Mucosal Immunol 2020 Aug 20;(): Hou Y, bioRxiv 2020;(): Jia H, Nat Commun 2020 Oct 14;11(1):5165 Li W, Proc Natl Acad Sci U S A 2020 Nov 24;117(47):29832-29838 Huang Q, Nat Commun 2021 Feb 3;12(1):776 Li D, Cell 2021 Aug 5;184(16):4203-4219.e32 | J:287092 J:288386 J:288402 J:294063 J:295328 J:295349 J:295350 J:295381 J:296535 J:299936 J:302315 J:313328 | Infection Pathology|SARS-CoV-2_virus SARS-CoV-2_virus Infection|SARS-CoV-2-MA_virus|Treatment Infection|SARS-CoV-2_virus MERS-CoV-MA_virus|MERS-CoV_virus|SARS-CoV-2-MA_virus|SARS-CoV-2_virus|SARS-CoV_virus MERS-CoV-MA_virus|MERS-CoV_virus|SARS-CoV-2-MA_virus|SARS-CoV-2_virus|SARS-CoV-MA_virus|SARS-CoV_virus SARS-CoV-2-MA_virus|SARS-CoV-2_virus|Treatment SARS-CoV-2_virus|Vaccine SARS-CoV-2-MA_virus|SARS-CoV-2_virus|SARS-CoV_virus|Treatment | Tg(FOXJ1-ACE2)1RbaTransgenic |
MGI:6415340 | cardiovascular system hematopoietic system homeostasis/metabolism immune system muscle respiratory system mortality/aging Coronavirus infectious disease COVID-19 severe acute respiratory syndrome |
Menachery VD, Proc Natl Acad Sci U S A 2016 Mar 15;113(11):3048-53 Jiang RD, Cell 2020 May 21;(): Lutz C, Hum Genomics 2020 Jun 4;14(1):20 Dinnon KH 3rd, Nature 2020 Aug 27;(): Leist SR, Dis Model Mech 2020 Sep 1;13(9):dmm046581 Singh A, Virol Sin 2020 Jun;35(3):290-304 Johansen MD, Mucosal Immunol 2020 Aug 20;(): Hou Y, bioRxiv 2020;(): Jia H, Nat Commun 2020 Oct 14;11(1):5165 Li W, Proc Natl Acad Sci U S A 2020 Nov 24;117(47):29832-29838 Huang Q, Nat Commun 2021 Feb 3;12(1):776 Li D, Cell 2021 Aug 5;184(16):4203-4219.e32 |
Tg(H2-Aa-HLA-DPA1)1Lone | MGI:5494673 | Transgenic | Inserted expressed sequence | Brentville VA, bioRxiv 2021 Jun;(): | J:308658 | SARS-CoV-2_virus|Vaccine | Tg(H2-Aa-HLA-DPA1)1LoneTransgenic |
Brentville VA, bioRxiv 2021 Jun;(): |
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Tg(H2-Ab1-HLA-DPB1)1Lone | MGI:5494677 | Transgenic | Inserted expressed sequence | Brentville VA, bioRxiv 2021 Jun;(): | J:308658 | SARS-CoV-2_virus|Vaccine | Tg(H2-Ab1-HLA-DPB1)1LoneTransgenic |
Brentville VA, bioRxiv 2021 Jun;(): |
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Tg(HLA-A2*/H2-Kb)273Rtct | MGI:3851006 | Transgenic | Inserted expressed sequence | Prakash S, bioRxiv 2020;(): | J:295374 | SARS-CoV-2_virus|Vaccine | Tg(HLA-A2*/H2-Kb)273RtctTransgenic |
Prakash S, bioRxiv 2020;(): |
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Tg(HLA-A/H2-D/B2M)1Bpe | MGI:3711164 | Transgenic | Inserted expressed sequence | Brentville VA, bioRxiv 2021 Jun;(): | J:308658 | SARS-CoV-2_virus|Vaccine | Tg(HLA-A/H2-D/B2M)1BpeTransgenic |
Brentville VA, bioRxiv 2021 Jun;(): |
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Tg(HLA-DRA*0101,HLA-DRB1*0101)1Dma | MGI:5312109 | Transgenic | Inserted expressed sequence | Brentville VA, bioRxiv 2021 Jun;(): | J:308658 | SARS-CoV-2_virus|Vaccine | Tg(HLA-DRA*0101,HLA-DRB1*0101)1DmaTransgenic |
Brentville VA, bioRxiv 2021 Jun;(): |
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Tg(HLA-DRA*0101,HLA-DRB1*0101)1Dmz | MGI:3809457 | Transgenic | Humanized sequence|Inserted expressed sequence | Prakash S, bioRxiv 2020;(): | J:295374 | SARS-CoV-2_virus|Vaccine | Tg(HLA-DRA*0101,HLA-DRB1*0101)1DmzTransgenic |
Prakash S, bioRxiv 2020;(): |
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Tg(K18-ACE2)2Prlmn | MGI:6389235 | Transgenic | Humanized sequence|Inserted expressed sequence | MGI:6399965 MGI:6455041 | severe acute respiratory syndrome COVID-19 | DOID:2945 DOID:0080600 | cardiovascular system immune system respiratory system mortality/aging behavior/neurological cellular growth/size/body hematopoietic system homeostasis/metabolism liver/biliary system nervous system vision/eye | MP:0005385 MP:0005387 MP:0005388 MP:0010768 MP:0005386 MP:0005384 MP:0005378 MP:0005397 MP:0005376 MP:0005370 MP:0003631 MP:0005391 | Netland J, J Virol 2008 Aug;82(15):7264-75 McCray PB Jr, J Virol 2007 Jan;81(2):813-21 Zhao J, J Virol 2009 Mar;83(5):2368-73 Dediego ML, Virology 2008 Jul 5;376(2):379-89 Zumla A, Nat Rev Drug Discov 2016 May;15(5):327-47 Gretebeck LM, Curr Opin Virol 2015 Aug;13():123-9 Netland J, Virology 2010 Mar 30;399(1):120-128 Natoli S, Eur J Neurol 2020 Apr 25;(): Lutz C, Hum Genomics 2020 Jun 4;14(1):20 Moreau GB, Am J Trop Med Hyg 2020 Jul 28;(): Cleary SJ, Br J Pharmacol 2020 May 27;(): Mullick JB, Cell Mol Bioeng 2020 Jul 27;():1-11 Case JB, Cell Host Microbe 2020 Sep 9;28(3):465-474.e4 Winkler ES, Nat Immunol 2020 Aug 24;(): Golden JW, JCI Insight 2020 Aug 25;(): Johansen MD, Mucosal Immunol 2020 Aug 20;(): Munoz-Fontela C, Nature 2020 Sep 23;(): Clark JJ, bioRxiv 2020;(): Bai L, bioRxiv 2020;(): Rathnasinghe R, Emerg Microbes Infect 2020 Oct 17;():1-19 Jia H, Nat Commun 2020 Oct 14;11(1):5165 Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 Ho JSY , bioRxiv 2020 Dec;(): Zhang H, bioRxiv 2020 Dec;(): Kumari P, bioRxiv 2020 Dec;(): Chen JS, bioRxiv 2020 Sep 25;(): Winkler ES, bioRxiv 2020 Dec;(): Soni DK, bioRxiv 2020 Dec;(): Liu R, bioRxiv 2021 Jan;(): Garcia-Arriaza J, J Virol 2021 Jan 7;(): Yuan L, Emerg Microbes Infect 2020 Dec;9(1):949-961 Chen JS, J Virol 2021 Jan 13;(): Carossino M, bioRxiv 2021 Jan;(): Oladunni FS, Nat Commun 2020 Nov 30;11(1):6122 Ku MW, bioRxiv 2021 Feb;(): Dampalla CS, bioRxiv 2021 Feb;(): Noy-Porat T, bioRxiv 2021 Feb;(): Biswas R, bioRxiv 2021 Feb;(): Brunaugh AD, PLoS One 2021;16(2):e0246803 Yinda CK, PLoS Pathog 2021 Jan;17(1):e1009195 Song E, J Exp Med 2021 Mar 1;218(3): Arce VM, Cell Mol Immunol 2021 Jan 14;(): Case JB, bioRxiv 2021 Mar;(): Silvas J, bioRxiv 2021 Mar;(): Zhai C, bioRxiv 2021 Mar;(): Hassler L, bioRxiv 2021 Mar;(): Napolitano V, bioRxiv 2021 Mar;(): Hanke L, bioRxiv 2021 Mar;(): Hoffmann D, bioRxiv 2021 Mar;(): Ullah i, bioRxiv 2021 Mar;(): Zheng J, Nature 2021 Jan;589(7843):603-607 White KM, Science 2021 Feb 26;371(6532):926-931 Elia U, bioRxiv 2021 Mar;(): Liu R, Proc Natl Acad Sci U S A 2021 Mar 23;118(12):e2026785118 Rosenfeld R, Nat Commun 2021 Feb 11;12(1):944 Joag V, J Immunol 2021 Mar 1;206(5):931-935 Sims JJ, bioRxiv 2021 Apr;(): Cao H, bioRxiv 2021 Apr;(): Seehusen F, bioRxiv 2021 Apr;(): Idris A, bioRxiv 2021 Apr;(): Matchett WE, bioRxiv 2021 Apr;(): Seibert B, bioRxiv 2021 Apr;(): Zhang X, Cell 2021 Apr 15;184(8):2229-2238.e13 Johnson BA, Nature 2021 Mar;591(7849):293-299 Xian H, Immunity 2021 Jul 13;54(7):1463-1477.e11 Marx S, bioRxiv 2021 Aug;(): Ryu DK, bioRxiv 2021 Jul;(): Alvaradov DM, bioRxiv 2021 Aug;(): Li W, bioRxiv 2021 Aug;(): Tarres-Frexas F, bioRxiv 2021 Aug;(): Ndeupen S, bioRxiv 2021 Aug;(): Fumagalli V, bioRxiv 2021 Aug;(): Wagner TR, bioRxiv 2021 Aug;(): Ulrich L, bioRxiv 2021 Jun;(): Belouzard S, bioRxiv 2021 Jun;(): Madar-Balakirski N, bioRxiv 2021 Jul;(): Hunt AC, bioRxiv 2021 Jul;(): Grandi A, bioRxiv 2021 Jul;(): Afkhami S, bioRxiv 2021 Jul;(): Venzon M, bioRxiv 2021 Jul;(): Radvak P, bioRxiv 2021 Jun;(): Dong W, bioRxiv 2021 Jun;(): Melamed S, bioRxiv 2021 Jun;(): Conforti A, bioRxiv 2021 Jun;(): Chen JS, bioRxiv 2021 Jun;(): Mao T, bioRxiv 2021 Jun;(): Scaglione A, bioRxiv 2021 Jun;(): Visualization of SARS-CoV-2 infection dynamic., bioRxiv 2021 Jun;(): Chaparian RR, bioRxiv 2021 Apr;(): Shapira T, bioRxiv 2021 May;(): Horspool AM, bioRxiv 2021 May;(): Van Dyke MC, bioRxiv 2021 May;(): Stefan MA, bioRxiv 2021 May;(): Amruta N, bioRxiv 2021 May;(): Dong W, bioRxiv 2021 May;(): Joyce MGl Chen WH, bioRxiv 2021 May;(): Israelow B, bioRxiv 2021 May;(): Greer CD, bioRxiv 2021 Aug;(): Salzer R, bioRxiv 2021 May;(): McMillan CL, bioRxiv 2021 May;(): Ho JSY, Cell 2021 May 13;184(10):2618-2632.e17 Caceres CJ, Sci Rep 2021 May 5;11(1):9609 Noy-Porat T, iScience 2021 May 21;24(5):102479 Zheng M, Nat Immunol 2021 Jul;22(7):829-838 Subramaniam S, bioRxiv 2021 Aug;(): Hilligan KL, bioRxiv 2021 Aug;(): Colunga Biancatelli R, Am J Physiol Lung Cell Mol Physiol 2021 Jun;(): Hassan AO, Cell Rep 2021 Jul 27;36(4):109452 Turan RD, Sci Rep 2021 Aug 4;11(1):15799 Chan CEZ, PLoS One 2021;16(6):e0253487 Beaudoin-Bussieres G, bioRxiv 2021 Sep;(): Dhanyalayam D, bioRxiv 2021 Sep;(): Castro JT, bioRxiv 2021 Sep;(): Robertson SJ, bioRxiv 2021 Sep;(): Eltobgy M, bioRxiv 2021;(): Puhl AC, bioRxiv 2021;(): Sohn SY, mBio 2021 Nov 2;():e0275621 Li K, mBio 2021 Aug 31;12(4):e0097021 Kaiser R, JCI Insight 2021 Sep 22;6(18):e150862 Zhou R, bioRxiv 2021 Oct;(): Tada T, Cell Rep 2020 Dec 22;33(12):108528 Hong J, bioRxiv 2021 Oct;(): Mejia OR, bioRxiv 2021 Nov;(): Olivarria GM, bioRxiv 2021 Nov;(): Barreiro A, bioRxiv 2021 Dec;(): Chen Y, bioRxiv 2021 Nov;(): Chaves OA, bioRxiv 2021 Nov;(): Ng KW, bioRxiv 2021 Dec;(): Lin X, bioRxiv 2021 Dec;(): Zhao Y, bioRxiv 2021 Dec;(): Zani A, bioRxiv 2021Dec;(): Zhang L, bioRxiv 2021 Dec;(): Gregoire C, bioRxiv 2021 Dec;(): Puhl AC, bioRxiv 2021 Dec;(): Xiao Y, Cell 2021 Dec 9;184(25):6037-6051.e14 Liu X, mBio 2021 Apr 20;12(2): Gawish R, Elife 2022 Jan 13;11():e74623 Ku MW, EMBO Mol Med 2021 Dec 7;13(12):e14459 Khaddaj-Mallat R, Neurobiol Dis 2021 Dec;161():105561 Awosanya OD, Bone 2022 Jan;154():116227 Kim GN, PLoS Pathog 2021 Dec;17(12):e1010092 Qin Z, Theranostics 2021;11(16):8076-8091 Hassert M, PLoS Pathog 2020 Dec;16(12):e1009163 Ceon E, bioRxiv 2022 Jan;(): Jeong GU, bioRxiv 2022;(): Chong Z, bioRxiv 2022;(): Lee KS, bioRxiv 2022;(): Duty A, bioRxiv 2022;(): Tatham L, bioRxiv 2022;(): Mao T, bioRxiv 2022;(): Ying B, bioRxiv 2022 Feb;(): Liu Y, bioRxiv 2022 Feb;(): Bishop CR, bioRxiv 2022 Feb;(): Mann BJ, bioRxiv 2022 Feb;(): Ye C, bioRxiv 2022 Mar;(): Sun CP, PLoS Pathog 2021 Aug;17(8):e1009758 Smeyne RJ, bioRxiv 2022 Feb;(): Wenzel J, Nat Neurosci 2021 Nov;24(11):1522-1533 Cohen AA, bioRxiv 2022 Mar;(): Zhang L, bioRxiv 2022 Mar;(): Natekar JP, bioRxiv 2022 Apr;(): Jeong GU, bioRxiv 2022 Apr;(): Rizvi ZA, bioRxiv 2022 Apr;(): Chong Z, Cell Rep 2022 May 10;39(6):110799 Walls AC, Cell Rep 2022 Aug 30;40(9):111299 Bishop CR, PLoS Pathog 2022 Sep;18(9):e1010867 Zhang L, EMBO Mol Med 2022 Sep 12;():e16109 Israelow B, Sci Immunol 2021 Oct 15;6(64):eabl4509 Kim SH, Front Immunol 2022;13():1055811 de Almeida L, Sci Adv 2022 Sep 16;8(37):eabo5400 Manangeeswaran M, Front Immunol 2022;13():919815 Su P, Mol Brain 2022 Aug 9;15(1):71 Chen IP, Cell Rep 2022 Jul 19;40(3):111088 Winkler ES, J Virol 2022 Jan 12;96(1):e0151121 Pan R, mBio 2022 Jan 25;():e0366221 Qin C, Proc Natl Acad Sci U S A 2022 Jun 28;119(26):e2122897119 Solopov PA, Am J Pathol 2022 Jul;192(7):990-1000 Eltobgy MM, Proc Natl Acad Sci U S A 2022 May 24;119(21):e2202012119 Dhanyalayam D, Front Cardiovasc Med 2022;9():783974 Parray HA, PLoS Pathog 2022 Dec;18(12):e1010994 Humphries F, Sci Immunol 2021 May 18;6(59): Lee S, Nature 2021 Nov;599(7884):283-289 Hassan AO, Cell 2020 Oct 1;183(1):169-184.e13 Amarilla AA, Nat Commun 2021 Jun 8;12(1):3431 Dugan HL, Immunity 2021 Jun 8;54(6):1290-1303.e7 Jennewein MF, Cell Rep 2021 Jul 13;36(2):109353 Garcia-Ayllon MS, FASEB J 2021 Aug;35(8):e21745 Li M, Sci Immunol 2021 May 18;6(59): Callahan V, Viruses 2021 Jun 3;13(6): Achdout H, Nat Commun 2021 Oct 5;12(1):5819 Scaglione A, Front Immunol 2021;12():719077 Vitner EB, Life Sci Alliance 2022 Jan;5(1): Roberts LM, J Immunol 2021 Nov 15;207(10):2399-2404 Chaouat AE, PLoS Pathog 2021 Dec;17(12):e1010175 El-Shennawy L, Nat Commun 2022 Jan 20;13(1):405 Chen EC, Cell Rep 2021 Aug 24;36(8):109604 Bertoglio F, Cell Rep 2021 Jul 27;36(4):109433 Makdasi E, Cell Rep 2021 Sep 7;36(10):109679 Li W, Cell Rep 2022 Jan 11;38(2):110210 Konrath KM, Cell Rep 2022 Feb 1;38(5):110318 Joyce MG, Cell Rep 2021 Dec 21;37(12):110143 Ordonez AA, Commun Biol 2022 Mar 18;5(1):242 Schepens B, Sci Transl Med 2021 Nov 24;13(621):eabi7826 Hauser BM, Cell Rep 2022 Mar 22;38(12):110561 Syenina A, PLoS Biol 2022 May;20(5):e3001643 Suryadevara N, J Clin Invest 2022 Jun 1;132(11):e159062 Hong J, Proc Natl Acad Sci U S A 2022 May 3;119(18):e2201433119 Americo JL, Proc Natl Acad Sci U S A 2022 Jun 14;119(24):e2202069119 Dubuc I, Front Immunol 2022;13():893792 Zhu C, Nat Commun 2022 Aug 3;13(1):4503 Perez P, Front Immunol 2022;13():995235 Mao T, Science 2022 Nov 25;378(6622):eabo2523 Yang JH, Sci Rep 2023 Feb 27;13(1):3303 Oktay E, Commun Biol 2023 Mar 23;6(1):308 Weiss S, Int J Mol Sci 2023 May 5;24(9): Ying B, Sci Transl Med 2022 Feb 2;14(630):eabm3302 Dampalla CS, Proc Natl Acad Sci U S A 2021 Jul 20;118(29): Zhao S, Nat Commun 2021 Aug 9;12(1):4887 Drayman N, Science 2021 Aug 20;373(6557):931-936 VanBlargan LA, Immunity 2021 Aug 19;(): van Oosten L, mBio 2021 Oct 26;12(5):e0181321 Dong W, J Virol 2022 Jan 12;96(1):e0096421 Kim EH, J Virol 2022 Mar 23;96(6):e0187321 Villadiego J, Nat Neurosci 2023 Feb;26(2):226-238 Nagai M, Nat Commun 2023 Jun 30;14(1):3863 Hastie KM, Cell Rep 2023 May 30;42(5):112421 Tada T, Proc Natl Acad Sci U S A 2023 Jun 6;120(23):e2303509120 Wei WC, Front Pharmacol 2023;14():1125414 Robertson SJ, Nat Commun 2023 Jul 25;14(1):4481 Yang S, J Med Virol 2022 Aug;94(8):3605-3612 Gioia U, Nat Cell Biol 2023 Apr;25(4):550-564 Rizvi ZA, Commun Biol 2023 Sep 13;6(1):935 Hilligan KL, Nat Commun 2023 Dec 12;14(1):8229 Fessler MB, Am J Respir Cell Mol Biol 2023 Dec;69(6):638-648 Perez P, Front Immunol 2023;14():1264323 Lee YJ, Am J Pathol 2023 Jul;193(7):866-882 Ewart G, PLoS Pathog 2023 Aug;19(8):e1011328 Wong L-YR, mBio 2023 Oct 26;14(6):e0247623 Suberi A, Sci Transl Med 2023 Aug 16;15(709):eabq0603 Oliveira VLS, Front Immunol 2024;15():1378591 Matchett WE, J Immunol 2021 Jun 30;(): Jeong H, Dis Model Mech 2022 Nov 1;15(11):dmm049632 Dangi T, J Clin Invest 2022 Dec 1;132(23): Goncalves R, iScience 2023 Feb 17;26(2):105972 Cao L, Sci Transl Med 2022 Sep 7;14(661):eabm7621 Jaki L, Nat Commun 2023 Apr 10;14(1):1999 Ullah I, iScience 2024 Mar 15;27(3):109049 Avila-Nieto C, Nat Commun 2024 Mar 21;15(1):2349 Martin-Lopez E, eNeuro 2024 Jun;11(6):ENEURO.0106-24.2024 Duty JA, Med 2022 Oct 14;3(10):705-721.e11 Do MH, PLoS One 2023;18(9):e0291537 Kim JW, Front Immunol 2023;14():1271508 Kehrer T, Cell Host Microbe 2023 Oct 11;31(10):1668-1684.e12 van Bergen J, JCI Insight 2023 Nov 8;8(21): Lu A, Int J Mol Sci 2024 Feb 8;25(4): van Huizen M, PLoS Pathog 2024 Mar;20(3):e1012100 Mao T, Proc Natl Acad Sci U S A 2024 Apr 30;121(18):e2319566121 Mei M, Proc Natl Acad Sci U S A 2024 May 28;121(22):e2314166121 Slamanig S, EBioMedicine 2024 Jun 6;105():105185 | J:138136 J:283648 J:283997 J:283998 J:283999 J:284000 J:286214 J:287925 J:288402 J:291888 J:292835 J:294026 J:294058 J:294083 J:294084 J:295350 J:295351 J:296067 J:296212 J:296397 J:296535 J:296686 J:298250 J:298262 J:298267 J:298866 J:299082 J:299096 J:299104 J:300041 J:300104 J:300110 J:300428 J:300960 J:302144 J:302145 J:302148 J:302158 J:302248 J:302313 J:302314 J:302316 J:302703 J:302912 J:302918 J:302921 J:303204 J:303206 J:303207 J:303209 J:303220 J:303457 J:303462 J:303465 J:303472 J:303898 J:304613 J:304616 J:304647 J:304677 J:304678 J:304698 J:305460 J:307033 J:308159 J:308571 J:308573 J:308575 J:308578 J:308579 J:308580 J:308584 J:308585 J:308620 J:308621 J:308635 J:308636 J:308637 J:308639 J:308640 J:308642 J:308643 J:308647 J:308651 J:308652 J:308655 J:308656 J:308666 J:308672 J:308713 J:308716 J:308719 J:308721 J:308723 J:308724 J:308725 J:308726 J:308733 J:308745 J:308749 J:308889 J:308894 J:308895 J:308896 J:308903 J:309192 J:309197 J:309512 J:309629 J:309630 J:309634 J:310110 J:310121 J:310123 J:310124 J:311911 J:311915 J:312952 J:313329 J:313337 J:313436 J:313439 J:313447 J:315717 J:315722 J:315723 J:315729 J:315731 J:315739 J:315744 J:316763 J:316764 J:316765 J:316768 J:316769 J:317125 J:317455 J:318828 J:319366 J:319440 J:319441 J:319447 J:319458 J:319459 J:321756 J:321757 J:321761 J:321763 J:321764 J:321766 J:321770 J:321873 J:321879 J:321906 J:321910 J:321927 J:322631 J:322638 J:323957 J:324935 J:324936 J:324941 J:324951 J:325034 J:325089 J:328107 J:330016 J:330045 J:331753 J:331754 J:331763 J:331765 J:331766 J:331767 J:331773 J:331808 J:331821 J:331822 J:331823 J:331826 J:333745 J:333769 J:334872 J:335892 J:335897 J:335898 J:335899 J:335902 J:335904 J:335906 J:335907 J:335910 J:335914 J:335918 J:335919 J:335924 J:335928 J:335929 J:335930 J:335931 J:335933 J:335935 J:335939 J:335943 J:335945 J:335947 J:335949 J:335952 J:335960 J:335961 J:335969 J:335976 J:335986 J:335996 J:335997 J:336005 J:336008 J:336014 J:336016 J:336017 J:336018 J:336021 J:336025 J:336026 J:336189 J:337953 J:338412 J:338414 J:338420 J:338561 J:339218 J:339694 J:340506 J:343550 J:343658 J:343770 J:343773 J:343775 J:343780 J:343790 J:348063 J:348320 J:348325 J:348326 J:348327 J:348328 J:348329 J:348954 J:349496 J:349938 J:349963 J:349970 J:349971 J:349972 J:349973 J:349976 J:349977 J:349979 J:349980 J:350298 | Infection|SARS-CoV_virus Infection|Mouse_Hepatitis_virus|SARS-CoV_virus MERS-CoV_virus|SARS-CoV_virus SARS-CoV-MA_virus|SARS-CoV_virus|Vaccine Infection|SARS-CoV-2_virus SARS-CoV-2_virus Infection|Pathology|SARS-CoV-2_virus SARS-CoV-2_virus|SARS-CoV_virus SARS-CoV-2_virus|Vaccine Infection|Pathology|SARS-CoV-2_virus|Sex_bias MERS-CoV-MA_virus|MERS-CoV_virus|SARS-CoV-2-MA_virus|SARS-CoV-2_virus|SARS-CoV-MA_virus|SARS-CoV_virus SARS-CoV-2-MA_virus|SARS-CoV-2_virus|SARS-CoV_virus Comorbidity|Pathology|SARS-CoV-2_virus Comorbidity|SARS-CoV-2_virus Pathology|SARS-CoV-2_virus|Treatment SARS-CoV-2_virus|Treatment Vaccine MERS-CoV_virus|SARS-CoV-2_virus|SARS-CoV_virus Pathology|SARS-CoV-2_virus Gene|SARS-CoV-2_virus MERS-CoV_virus|SARS-CoV-2_virus|Treatment SARS-CoV-2_virus|Treatment|VOC_B.1.1.7_Alpha|VOC_B.1.351_Beta SARS-CoV-2_virus|Treatment|VOC_B.1.351_Beta SARS-CoV-2_virus|Vaccine|VOC_B.1.351_Beta SARS-CoV-2_virus|Treatment|VOC_B.1.617.2_Delta Treatment|VOC_B.1.1.7_Alpha|VOC_B.1.351_Beta|VOC_B.1.429|VOC_B.1.617.2_Delta|VOC_P.1_Gamma Infection|SARS-CoV-2_virus|VOC_B.1.351_Beta Infection|SARS-CoV-2_virus|VOC_B.1.1.7_Alpha|VOC_B.1.351_Beta SARS-CoV-2_virus|Treatment|VOC_P.1_Gamma SARS-CoV-2_virus|Treatment|VOC_B.1.1.7_Alpha|VOC_B.1.351_Beta|VOC_P.1_Gamma SARS-CoV-2_virus|Vaccine|VOC_B.1.1.7_Alpha|VOC_B.1.351_Beta Pathology|SARS-CoV-2_virus|VOC_B.1.1.7_Alpha|VOC_B.1.351_Beta SARS-CoV-2_virus|Treatment|VOC_B.1.1.7_Alpha SARS-CoV-2_virus|VOC_B.1.351_Beta Treatment|VOC_B.1.1.7_Alpha|VOC_B.1.351_Beta|VOC_P.1_Gamma SARS-CoV-2_virus|VOC_B.1.1.7_Alpha|VOC_B.1.351_Beta Gene|SARS-CoV-2-MA_virus SARS-CoV-2_virus|Treatment|VOC_B.1.1.7_Alpha|VOC_B.1.351_Beta|VOC_B.1.617.2_Delta|VOC_P.1_Gamma Comorbidity|SARS-CoV-2-MA_virus|SARS-CoV-2_virus Gene|Pathology|SARS-CoV-2_virus Vaccine|VOC_B.1.1.7_Alpha|VOC_B.1.351_Beta|VOC_B.1.617.2_Delta Gene|SARS-CoV-2-MA_virus|SARS-CoV-2_virus Mouse_Hepatitis_virus|SARS-CoV-2_virus|Treatment SARS-CoV-2_virus|Treatment|VOC_B.1.1.7_Alpha|VOC_B.1.427|VOC_B.1.617.2_Delta Pathology|SARS-CoV-2-MA_virus SARS-CoV-2_virus|Vaccine|VOC_P.1_Gamma SARS-CoV-2_virus|Treatment|VOC_B.1.1.529_Omicron|VOC_B.1.351_Beta Pathology|VOC_B.1.617.2_Delta Treatment|VOC_B.1.1.529_Omicron|VOC_B.1.1.7_Alpha|VOC_B.1.351_Beta|VOC_B.1.617.2_Delta|VOC_P.1_Gamma Treatment|VOC_B.1.1.529_Omicron|VOC_B.1.617.2_Delta Vaccine|VOC_B.1.1.529_Omicron Pathology PASC|SARS-CoV-2_virus Pathology|SARS-CoV-2_virus|VOC_B.1.351_Beta SARS-CoV-2_virus|Treatment|Variant|VOC_B.1.1.529_Omicron|VOC_P.1_Gamma Infection|SARS-CoV-2-MA_virus|SARS-CoV-2_virus|VOC_B.1.1.529_Omicron|VOC_B.1.1.7_Alpha|VOC_B.1.351_Beta|VOC_B.1.617.2_Delta Infection|Pathology|SARS-CoV-2_virus|VOC_B.1.1.529_Omicron|VOC_B.1.617.2_Delta SARS-CoV-2_virus|Vaccine|Variant|VOC_B.1.351_Beta SARS-CoV-2-MA_virus|SARS-CoV-2_virus SARS-CoV-2_virus|Treatment|VOC_B.1.1.529_Omicron Infection|Mouse_Hepatitis_virus|SARS-CoV-2_virus Infection|SARS-CoV-2_virus|Treatment Comorbidity|SARS-CoV-2_virus|Sex_bias SARS-CoV-2_virus|Treatment|Variant SARS-CoV-2_virus|Treatment|Vaccine SARS-CoV-2_virus|Treatment|VOC_B.1.1.529_Omicron|VOC_B.1.617.2_Delta SARS-CoV-2_virus|Treatment|VOC_B.1.351_Beta|VOC_B.1.617.2_Delta SARS-CoV-2_virus|Vaccine|Variant SARS-CoV-2-MA_virus|SARS-CoV-2_virus|Vaccine|VOC_B.1.1.7_Alpha|VOC_B.1.351_Beta|VOC_B.1.617.2_Delta Comorbidity|Infection|SARS-CoV-2_virus Pathology|SARS-CoV-2_virus|Vaccine SARS-CoV-2_virus|VOC_B.1.1.7_Alpha Pathology|SARS-CoV-2_virus|VOC_B.1.617.2_Delta Pathology|SARS-CoV-2_virus|VOC_B.1.1.529_Omicron Pathology|SARS-CoV-2_virus|VOC_B.1.1.529_Omicron|VOC_B.1.617.2_Delta MERS-CoV-MA_virus|Pathology|SARS-CoV-2_virus Mouse_Hepatitis_virus|SARS-CoV-2_virus|Treatment|VOC_P.1_Gamma Pathology|SARS-CoV-2_virus|VOC_B.1.1.529_Omicron|VOC_B.1.1.7_Alpha|VOC_B.1.617.2_Delta SARS-CoV-2_virus|Vaccine|VOC_B.1.1.529_Omicron|VOC_B.1.351_Beta Infection|Pathology|SARS-CoV-2_virus|Variant SARS-CoV-2_virus|SARS-CoV_virus|Vaccine|VOC_B.1.1.529_Omicron | Tg(K18-ACE2)2PrlmnTransgenic |
MGI:6399965 MGI:6455041 | cardiovascular system immune system respiratory system mortality/aging severe acute respiratory syndrome behavior/neurological cellular growth/size/body hematopoietic system homeostasis/metabolism liver/biliary system nervous system vision/eye COVID-19 |
Netland J, J Virol 2008 Aug;82(15):7264-75 McCray PB Jr, J Virol 2007 Jan;81(2):813-21 Zhao J, J Virol 2009 Mar;83(5):2368-73 Dediego ML, Virology 2008 Jul 5;376(2):379-89 Zumla A, Nat Rev Drug Discov 2016 May;15(5):327-47 Gretebeck LM, Curr Opin Virol 2015 Aug;13():123-9 Netland J, Virology 2010 Mar 30;399(1):120-128 Natoli S, Eur J Neurol 2020 Apr 25;(): Lutz C, Hum Genomics 2020 Jun 4;14(1):20 Moreau GB, Am J Trop Med Hyg 2020 Jul 28;(): Cleary SJ, Br J Pharmacol 2020 May 27;(): Mullick JB, Cell Mol Bioeng 2020 Jul 27;():1-11 Case JB, Cell Host Microbe 2020 Sep 9;28(3):465-474.e4 Winkler ES, Nat Immunol 2020 Aug 24;(): Golden JW, JCI Insight 2020 Aug 25;(): Johansen MD, Mucosal Immunol 2020 Aug 20;(): Munoz-Fontela C, Nature 2020 Sep 23;(): Clark JJ, bioRxiv 2020;(): Bai L, bioRxiv 2020;(): Rathnasinghe R, Emerg Microbes Infect 2020 Oct 17;():1-19 Jia H, Nat Commun 2020 Oct 14;11(1):5165 Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 Ho JSY , bioRxiv 2020 Dec;(): Zhang H, bioRxiv 2020 Dec;(): Kumari P, bioRxiv 2020 Dec;(): Chen JS, bioRxiv 2020 Sep 25;(): Winkler ES, bioRxiv 2020 Dec;(): Soni DK, bioRxiv 2020 Dec;(): Liu R, bioRxiv 2021 Jan;(): Garcia-Arriaza J, J Virol 2021 Jan 7;(): Yuan L, Emerg Microbes Infect 2020 Dec;9(1):949-961 Chen JS, J Virol 2021 Jan 13;(): Carossino M, bioRxiv 2021 Jan;(): Oladunni FS, Nat Commun 2020 Nov 30;11(1):6122 Ku MW, bioRxiv 2021 Feb;(): Dampalla CS, bioRxiv 2021 Feb;(): Noy-Porat T, bioRxiv 2021 Feb;(): Biswas R, bioRxiv 2021 Feb;(): Brunaugh AD, PLoS One 2021;16(2):e0246803 Yinda CK, PLoS Pathog 2021 Jan;17(1):e1009195 Song E, J Exp Med 2021 Mar 1;218(3): Arce VM, Cell Mol Immunol 2021 Jan 14;(): Case JB, bioRxiv 2021 Mar;(): Silvas J, bioRxiv 2021 Mar;(): Zhai C, bioRxiv 2021 Mar;(): Hassler L, bioRxiv 2021 Mar;(): Napolitano V, bioRxiv 2021 Mar;(): Hanke L, bioRxiv 2021 Mar;(): Hoffmann D, bioRxiv 2021 Mar;(): Ullah i, bioRxiv 2021 Mar;(): Zheng J, Nature 2021 Jan;589(7843):603-607 White KM, Science 2021 Feb 26;371(6532):926-931 Elia U, bioRxiv 2021 Mar;(): Liu R, Proc Natl Acad Sci U S A 2021 Mar 23;118(12):e2026785118 Rosenfeld R, Nat Commun 2021 Feb 11;12(1):944 Joag V, J Immunol 2021 Mar 1;206(5):931-935 Sims JJ, bioRxiv 2021 Apr;(): Cao H, bioRxiv 2021 Apr;(): Seehusen F, bioRxiv 2021 Apr;(): Idris A, bioRxiv 2021 Apr;(): Matchett WE, bioRxiv 2021 Apr;(): Seibert B, bioRxiv 2021 Apr;(): Zhang X, Cell 2021 Apr 15;184(8):2229-2238.e13 Johnson BA, Nature 2021 Mar;591(7849):293-299 Xian H, Immunity 2021 Jul 13;54(7):1463-1477.e11 Marx S, bioRxiv 2021 Aug;(): Ryu DK, bioRxiv 2021 Jul;(): Alvaradov DM, bioRxiv 2021 Aug;(): Li W, bioRxiv 2021 Aug;(): Tarres-Frexas F, bioRxiv 2021 Aug;(): Ndeupen S, bioRxiv 2021 Aug;(): Fumagalli V, bioRxiv 2021 Aug;(): Wagner TR, bioRxiv 2021 Aug;(): Ulrich L, bioRxiv 2021 Jun;(): Belouzard S, bioRxiv 2021 Jun;(): Madar-Balakirski N, bioRxiv 2021 Jul;(): Ryu DK, bioRxiv 2021 Jul;(): Hunt AC, bioRxiv 2021 Jul;(): Grandi A, bioRxiv 2021 Jul;(): Afkhami S, bioRxiv 2021 Jul;(): Venzon M, bioRxiv 2021 Jul;(): Radvak P, bioRxiv 2021 Jun;(): Dong W, bioRxiv 2021 Jun;(): Melamed S, bioRxiv 2021 Jun;(): Conforti A, bioRxiv 2021 Jun;(): Chen JS, bioRxiv 2021 Jun;(): Mao T, bioRxiv 2021 Jun;(): Scaglione A, bioRxiv 2021 Jun;(): Visualization of SARS-CoV-2 infection dynamic., bioRxiv 2021 Jun;(): Chaparian RR, bioRxiv 2021 Apr;(): Shapira T, bioRxiv 2021 May;(): Horspool AM, bioRxiv 2021 May;(): Van Dyke MC, bioRxiv 2021 May;(): Stefan MA, bioRxiv 2021 May;(): Amruta N, bioRxiv 2021 May;(): Dong W, bioRxiv 2021 May;(): Joyce MGl Chen WH, bioRxiv 2021 May;(): Israelow B, bioRxiv 2021 May;(): Greer CD, bioRxiv 2021 Aug;(): Salzer R, bioRxiv 2021 May;(): McMillan CL, bioRxiv 2021 May;(): Ho JSY, Cell 2021 May 13;184(10):2618-2632.e17 Caceres CJ, Sci Rep 2021 May 5;11(1):9609 Noy-Porat T, iScience 2021 May 21;24(5):102479 Zheng M, Nat Immunol 2021 Jul;22(7):829-838 Subramaniam S, bioRxiv 2021 Aug;(): Hilligan KL, bioRxiv 2021 Aug;(): Colunga Biancatelli R, Am J Physiol Lung Cell Mol Physiol 2021 Jun;(): Hassan AO, Cell Rep 2021 Jul 27;36(4):109452 Turan RD, Sci Rep 2021 Aug 4;11(1):15799 Chan CEZ, PLoS One 2021;16(6):e0253487 Beaudoin-Bussieres G, bioRxiv 2021 Sep;(): Dhanyalayam D, bioRxiv 2021 Sep;(): Castro JT, bioRxiv 2021 Sep;(): Robertson SJ, bioRxiv 2021 Sep;(): Eltobgy M, bioRxiv 2021;(): Puhl AC, bioRxiv 2021;(): Sohn SY, mBio 2021 Nov 2;():e0275621 Li K, mBio 2021 Aug 31;12(4):e0097021 Kaiser R, JCI Insight 2021 Sep 22;6(18):e150862 Zhou R, bioRxiv 2021 Oct;(): Tada T, Cell Rep 2020 Dec 22;33(12):108528 Hong J, bioRxiv 2021 Oct;(): Mejia OR, bioRxiv 2021 Nov;(): Olivarria GM, bioRxiv 2021 Nov;(): Barreiro A, bioRxiv 2021 Dec;(): Chen Y, bioRxiv 2021 Nov;(): Chaves OA, bioRxiv 2021 Nov;(): Ng KW, bioRxiv 2021 Dec;(): Lin X, bioRxiv 2021 Dec;(): Zhao Y, bioRxiv 2021 Dec;(): Zani A, bioRxiv 2021Dec;(): Zhang L, bioRxiv 2021 Dec;(): Gregoire C, bioRxiv 2021 Dec;(): Puhl AC, bioRxiv 2021 Dec;(): Xiao Y, Cell 2021 Dec 9;184(25):6037-6051.e14 Liu X, mBio 2021 Apr 20;12(2): Gawish R, Elife 2022 Jan 13;11():e74623 Ku MW, EMBO Mol Med 2021 Dec 7;13(12):e14459 Khaddaj-Mallat R, Neurobiol Dis 2021 Dec;161():105561 Awosanya OD, Bone 2022 Jan;154():116227 Kim GN, PLoS Pathog 2021 Dec;17(12):e1010092 Qin Z, Theranostics 2021;11(16):8076-8091 Hassert M, PLoS Pathog 2020 Dec;16(12):e1009163 Ceon E, bioRxiv 2022 Jan;(): Jeong GU, bioRxiv 2022;(): Chong Z, bioRxiv 2022;(): Lee KS, bioRxiv 2022;(): Duty A, bioRxiv 2022;(): Tatham L, bioRxiv 2022;(): Mao T, bioRxiv 2022;(): Ying B, bioRxiv 2022 Feb;(): Liu Y, bioRxiv 2022 Feb;(): Bishop CR, bioRxiv 2022 Feb;(): Mann BJ, bioRxiv 2022 Feb;(): Ye C, bioRxiv 2022 Mar;(): Sun CP, PLoS Pathog 2021 Aug;17(8):e1009758 Smeyne RJ, bioRxiv 2022 Feb;(): Wenzel J, Nat Neurosci 2021 Nov;24(11):1522-1533 Cohen AA, bioRxiv 2022 Mar;(): Zhang L, bioRxiv 2022 Mar;(): Natekar JP, bioRxiv 2022 Apr;(): Jeong GU, bioRxiv 2022 Apr;(): Rizvi ZA, bioRxiv 2022 Apr;(): Chong Z, Cell Rep 2022 May 10;39(6):110799 Walls AC, Cell Rep 2022 Aug 30;40(9):111299 Bishop CR, PLoS Pathog 2022 Sep;18(9):e1010867 Zhang L, EMBO Mol Med 2022 Sep 12;():e16109 Israelow B, Sci Immunol 2021 Oct 15;6(64):eabl4509 Kim SH, Front Immunol 2022;13():1055811 de Almeida L, Sci Adv 2022 Sep 16;8(37):eabo5400 Manangeeswaran M, Front Immunol 2022;13():919815 Su P, Mol Brain 2022 Aug 9;15(1):71 Chen IP, Cell Rep 2022 Jul 19;40(3):111088 Winkler ES, J Virol 2022 Jan 12;96(1):e0151121 Pan R, mBio 2022 Jan 25;():e0366221 Qin C, Proc Natl Acad Sci U S A 2022 Jun 28;119(26):e2122897119 Solopov PA, Am J Pathol 2022 Jul;192(7):990-1000 Eltobgy MM, Proc Natl Acad Sci U S A 2022 May 24;119(21):e2202012119 Dhanyalayam D, Front Cardiovasc Med 2022;9():783974 Parray HA, PLoS Pathog 2022 Dec;18(12):e1010994 Humphries F, Sci Immunol 2021 May 18;6(59): Lee S, Nature 2021 Nov;599(7884):283-289 Hassan AO, Cell 2020 Oct 1;183(1):169-184.e13 Amarilla AA, Nat Commun 2021 Jun 8;12(1):3431 Dugan HL, Immunity 2021 Jun 8;54(6):1290-1303.e7 Jennewein MF, Cell Rep 2021 Jul 13;36(2):109353 Garcia-Ayllon MS, FASEB J 2021 Aug;35(8):e21745 Li M, Sci Immunol 2021 May 18;6(59): Callahan V, Viruses 2021 Jun 3;13(6): Achdout H, Nat Commun 2021 Oct 5;12(1):5819 Scaglione A, Front Immunol 2021;12():719077 Vitner EB, Life Sci Alliance 2022 Jan;5(1): Roberts LM, J Immunol 2021 Nov 15;207(10):2399-2404 Chaouat AE, PLoS Pathog 2021 Dec;17(12):e1010175 El-Shennawy L, Nat Commun 2022 Jan 20;13(1):405 Chen EC, Cell Rep 2021 Aug 24;36(8):109604 Bertoglio F, Cell Rep 2021 Jul 27;36(4):109433 Makdasi E, Cell Rep 2021 Sep 7;36(10):109679 Li W, Cell Rep 2022 Jan 11;38(2):110210 Konrath KM, Cell Rep 2022 Feb 1;38(5):110318 Joyce MG, Cell Rep 2021 Dec 21;37(12):110143 Ordonez AA, Commun Biol 2022 Mar 18;5(1):242 Schepens B, Sci Transl Med 2021 Nov 24;13(621):eabi7826 Hauser BM, Cell Rep 2022 Mar 22;38(12):110561 Syenina A, PLoS Biol 2022 May;20(5):e3001643 Suryadevara N, J Clin Invest 2022 Jun 1;132(11):e159062 Hong J, Proc Natl Acad Sci U S A 2022 May 3;119(18):e2201433119 Americo JL, Proc Natl Acad Sci U S A 2022 Jun 14;119(24):e2202069119 Dubuc I, Front Immunol 2022;13():893792 Zhu C, Nat Commun 2022 Aug 3;13(1):4503 Perez P, Front Immunol 2022;13():995235 Mao T, Science 2022 Nov 25;378(6622):eabo2523 Yang JH, Sci Rep 2023 Feb 27;13(1):3303 Oktay E, Commun Biol 2023 Mar 23;6(1):308 Weiss S, Int J Mol Sci 2023 May 5;24(9): Ying B, Sci Transl Med 2022 Feb 2;14(630):eabm3302 Dampalla CS, Proc Natl Acad Sci U S A 2021 Jul 20;118(29): Zhao S, Nat Commun 2021 Aug 9;12(1):4887 Drayman N, Science 2021 Aug 20;373(6557):931-936 VanBlargan LA, Immunity 2021 Aug 19;(): van Oosten L, mBio 2021 Oct 26;12(5):e0181321 Dong W, J Virol 2022 Jan 12;96(1):e0096421 Kim EH, J Virol 2022 Mar 23;96(6):e0187321 Villadiego J, Nat Neurosci 2023 Feb;26(2):226-238 Nagai M, Nat Commun 2023 Jun 30;14(1):3863 Hastie KM, Cell Rep 2023 May 30;42(5):112421 Tada T, Proc Natl Acad Sci U S A 2023 Jun 6;120(23):e2303509120 Wei WC, Front Pharmacol 2023;14():1125414 Robertson SJ, Nat Commun 2023 Jul 25;14(1):4481 Yang S, J Med Virol 2022 Aug;94(8):3605-3612 Gioia U, Nat Cell Biol 2023 Apr;25(4):550-564 Rizvi ZA, Commun Biol 2023 Sep 13;6(1):935 Hilligan KL, Nat Commun 2023 Dec 12;14(1):8229 Fessler MB, Am J Respir Cell Mol Biol 2023 Dec;69(6):638-648 Perez P, Front Immunol 2023;14():1264323 Lee YJ, Am J Pathol 2023 Jul;193(7):866-882 Ewart G, PLoS Pathog 2023 Aug;19(8):e1011328 Wong L-YR, mBio 2023 Oct 26;14(6):e0247623 Suberi A, Sci Transl Med 2023 Aug 16;15(709):eabq0603 Oliveira VLS, Front Immunol 2024;15():1378591 Matchett WE, J Immunol 2021 Jun 30;(): Jeong H, Dis Model Mech 2022 Nov 1;15(11):dmm049632 Dangi T, J Clin Invest 2022 Dec 1;132(23): Goncalves R, iScience 2023 Feb 17;26(2):105972 Cao L, Sci Transl Med 2022 Sep 7;14(661):eabm7621 Jaki L, Nat Commun 2023 Apr 10;14(1):1999 Ullah I, iScience 2024 Mar 15;27(3):109049 Avila-Nieto C, Nat Commun 2024 Mar 21;15(1):2349 Martin-Lopez E, eNeuro 2024 Jun;11(6):ENEURO.0106-24.2024 Duty JA, Med 2022 Oct 14;3(10):705-721.e11 Do MH, PLoS One 2023;18(9):e0291537 Kim JW, Front Immunol 2023;14():1271508 Kehrer T, Cell Host Microbe 2023 Oct 11;31(10):1668-1684.e12 van Bergen J, JCI Insight 2023 Nov 8;8(21): Lu A, Int J Mol Sci 2024 Feb 8;25(4): van Huizen M, PLoS Pathog 2024 Mar;20(3):e1012100 Mao T, Proc Natl Acad Sci U S A 2024 Apr 30;121(18):e2319566121 Mei M, Proc Natl Acad Sci U S A 2024 May 28;121(22):e2314166121 Slamanig S, EBioMedicine 2024 Jun 6;105():105185 |
Tg(KRT18-DPP4)3Pbmj | MGI:6402178 | Transgenic | Epitope tag|Humanized sequence|Inserted expressed sequence | MGI:6402203 | Middle East respiratory syndrome | DOID:0080642 | cardiovascular system digestive/alimentary system hematopoietic system homeostasis/metabolism immune system nervous system renal/urinary system respiratory system mortality/aging | MP:0005385 MP:0005381 MP:0005397 MP:0005376 MP:0005387 MP:0003631 MP:0005367 MP:0005388 MP:0010768 | Li K, J Infect Dis 2016 Mar 1;213(5):712-22 Leist SR, Methods Mol Biol 2020;2099():137-159 Zhou J, Sci Adv 2017 Nov;3(11):eaao4966 Yuan S, Nat Commun 2019 Jan 10;10(1):120 Rathnayake AD, Sci Transl Med 2020 Aug 3;(): Knaap RC, bioRxiv 2019;(): Gutierrez-Alvarez J, Proc Natl Acad Sci U S A 2021 Oct 26;118(43):e2111075118 | J:285467 J:285962 J:286231 J:291634 J:291887 J:295365 J:315826 | Infection|MERS-CoV_virus|Pathology MERS-CoV_virus Infection|MERS-CoV_virus MERS-CoV_virus|Treatment MERS-CoV_virus|SARS-CoV-2_virus|SARS-CoV_virus|Treatment MERS-CoV_virus|Vaccine | Tg(KRT18-DPP4)3PbmjTransgenic |
MGI:6402203 | cardiovascular system digestive/alimentary system hematopoietic system homeostasis/metabolism immune system nervous system renal/urinary system respiratory system mortality/aging Middle East respiratory syndrome |
Li K, J Infect Dis 2016 Mar 1;213(5):712-22 Leist SR, Methods Mol Biol 2020;2099():137-159 Zhou J, Sci Adv 2017 Nov;3(11):eaao4966 Yuan S, Nat Commun 2019 Jan 10;10(1):120 Rathnayake AD, Sci Transl Med 2020 Aug 3;(): Knaap RC, bioRxiv 2019;(): Gutierrez-Alvarez J, Proc Natl Acad Sci U S A 2021 Oct 26;118(43):e2111075118 |
Tg(Myh6-ACE2)1Rbre | MGI:6459902 | Transgenic | Humanized sequence|Inserted expressed sequence | Jia H, Nat Commun 2020 Oct 14;11(1):5165 | J:296535 | SARS-CoV-2_virus | Tg(Myh6-ACE2)1RbreTransgenic |
Jia H, Nat Commun 2020 Oct 14;11(1):5165 |
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Tg(Myh6-ACE2)2Rbre | MGI:6459903 | Transgenic | Humanized sequence|Inserted expressed sequence | Jia H, Nat Commun 2020 Oct 14;11(1):5165 | J:296535 | SARS-CoV-2_virus | Tg(Myh6-ACE2)2RbreTransgenic |
Jia H, Nat Commun 2020 Oct 14;11(1):5165 |
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Tg(PSEN1)5Dbo | MGI:2447335 | Transgenic | Humanized sequence|Inserted expressed sequence | Chen J, Transl Psychiatry 2023 Dec 16;13(1):396 | J:348471 | Gene|Infection|SARS-CoV-2_virus | Tg(PSEN1)5DboTransgenic |
Chen J, Transl Psychiatry 2023 Dec 16;13(1):396 |
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Tg(SFTPC-DPP4)3Pbmj | MGI:6402180 | Transgenic | Epitope tag|Humanized sequence|Inserted expressed sequence | MGI:6402208 | immune system | MP:0005387 | Li K, J Infect Dis 2016 Mar 1;213(5):712-22 | J:285467 | Infection|MERS-CoV_virus|Pathology | Tg(SFTPC-DPP4)3PbmjTransgenic |
MGI:6402208 | immune system |
Li K, J Infect Dis 2016 Mar 1;213(5):712-22 |
||
Tg(SIRPA)1Flv | MGI:5300383 | Transgenic | Humanized sequence|Inserted expressed sequence | Sefik E, bioRxiv 2021;(): | J:311907 | SARS-CoV-2_virus | Tg(SIRPA)1FlvTransgenic |
Sefik E, bioRxiv 2021;(): |
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Tg(Sry)2Ei | MGI:3041982 | Transgenic | Inserted expressed sequence | Ensor CM, bioRxiv 2021-09;(): | J:310122 | SARS-CoV-2_virus | Tg(Sry)2EiTransgenic |
Ensor CM, bioRxiv 2021-09;(): |
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Tg(Syn1-ACE2)10Sig | MGI:6401191 | Transgenic | Humanized sequence|Inserted expressed sequence | Jia H, Nat Commun 2020 Oct 14;11(1):5165 | J:296535 | SARS-CoV-2_virus | Tg(Syn1-ACE2)10SigTransgenic |
Jia H, Nat Commun 2020 Oct 14;11(1):5165 |
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Tg(TcraTcrb)425Cbn | MGI:3046083 | Transgenic | Inserted expressed sequence | Zhao J, J Exp Med 2011 Aug 1;208(8):1571-7 | J:177608 | Mouse_Hepatitis_virus | Tg(TcraTcrb)425CbnTransgenic |
Zhao J, J Exp Med 2011 Aug 1;208(8):1571-7 |
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Tg(TcrLCMV)#Sdz | MGI:4838215 | Transgenic | Inserted expressed sequence | Perez-Shibayama C, PLoS One 2013;8(11):e81442 | J:291632 | Mouse_Hepatitis_virus | Tg(TcrLCMV)#SdzTransgenic |
Perez-Shibayama C, PLoS One 2013;8(11):e81442 |
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Tg(Tek-cre)1Ywa | MGI:2450311 | Transgenic | Hypomorph|Recombinase | Gao S, Front Cardiovasc Med 2023;10():1266276 | J:346048 | Infection|SARS-CoV-2_virus | Tg(Tek-cre)1YwaTransgenic |
Gao S, Front Cardiovasc Med 2023;10():1266276 |
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Tg(tetO-GFP,-APOL1)#Susz | MGI:6331297 | Transgenic | Humanized sequence|Inducible|Inserted expressed sequence|Reporter | Wu J, Immunity 2021 Nov 9;54(11):2632-2649.e6 | J:323769 | Gene|Pathology | Tg(tetO-GFP,-APOL1)#SuszTransgenic |
Wu J, Immunity 2021 Nov 9;54(11):2632-2649.e6 |
|||||||
Tg(tetO-GFP,-APOL1*)#Susz | MGI:6331300 | Transgenic | Humanized sequence|Inducible|Inserted expressed sequence|Reporter | Wu J, Immunity 2021 Nov 9;54(11):2632-2649.e6 | J:323769 | Gene|Pathology | Tg(tetO-GFP,-APOL1*)#SuszTransgenic |
Wu J, Immunity 2021 Nov 9;54(11):2632-2649.e6 |
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Tg(Thy1-APPSwe,Prnp-PSEN2*N141I)152HLaoz | MGI:4412048 | Transgenic | Humanized sequence|Inserted expressed sequence | Magusali N, bioRxiv 2021 Mar;(): | J:303205 | Comorbidity | Tg(Thy1-APPSwe,Prnp-PSEN2*N141I)152HLaozTransgenic |
Magusali N, bioRxiv 2021 Mar;(): |
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Tg(Tk1-DPP4)27Ysj | MGI:6443611 | Transgenic | Epitope tag|Humanized sequence|Inserted expressed sequence | MGI:6443613 | Middle East respiratory syndrome | DOID:0080642 | behavior/neurological cardiovascular system growth/size/body hematopoietic system homeostasis/metabolism immune system integument nervous system respiratory system mortality/aging | MP:0005386 MP:0005385 MP:0005378 MP:0005397 MP:0005376 MP:0005387 MP:0010771 MP:0003631 MP:0005388 MP:0010768 | Kim J, J Microbiol Biotechnol 2020 Mar 28;30(3):427-438 | J:290259 | Infection|MERS-CoV_virus|Pathology | Tg(Tk1-DPP4)27YsjTransgenic |
MGI:6443613 | behavior/neurological cardiovascular system growth/size/body hematopoietic system homeostasis/metabolism immune system integument nervous system respiratory system mortality/aging Middle East respiratory syndrome |
Kim J, J Microbiol Biotechnol 2020 Mar 28;30(3):427-438 |
Thpotm1.1(TPO)Flv | MGI:4887867 | Targeted | Humanized sequence|Inserted expressed sequence | Sefik E, bioRxiv 2021;(): | J:311907 | SARS-CoV-2_virus | Thpotm1.1(TPO)FlvTargeted |
Sefik E, bioRxiv 2021;(): |
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Ticam1Lps2 | MGI:2679794 | Chemically induced (ENU) | Not Specified | MGI:5520919 | cardiovascular system hematopoietic system homeostasis/metabolism immune system respiratory system mortality/aging | MP:0005385 MP:0005397 MP:0005376 MP:0005387 MP:0005388 MP:0010768 | Totura AL, mBio 2015 May 26;6(3):e00638-15 | J:288471 | Infection|SARS-CoV-MA_virus | Ticam1Lps2Chemically induced (ENU) |
MGI:5520919 | cardiovascular system hematopoietic system homeostasis/metabolism immune system respiratory system mortality/aging |
Totura AL, mBio 2015 May 26;6(3):e00638-15 |
||
Ticam1tm1Aki | MGI:3029019 | Targeted | Null/knockout | MGI:3029024 | cellular hematopoietic system homeostasis/metabolism immune system nervous system | MP:0005384 MP:0005397 MP:0005376 MP:0005387 MP:0003631 | Imai Y, Cell 2008 Apr 18;133(2):235-49 Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 Zheng M, Nat Immunol 2021 Jul;22(7):829-838 | J:145306 J:296686 J:308903 | SARS-CoV_virus Pathology|SARS-CoV-2_virus|Treatment Pathology|SARS-CoV-2_virus | Ticam1tm1AkiTargeted |
MGI:3029024 | cellular hematopoietic system homeostasis/metabolism immune system nervous system |
Imai Y, Cell 2008 Apr 18;133(2):235-49 Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 Zheng M, Nat Immunol 2021 Jul;22(7):829-838 |
||
Ticam2tm1Aki | MGI:3040182 | Targeted | Null/knockout | MGI:3040184 | Coronavirus infectious disease | DOID:0080599 | immune system | MP:0005387 | Gralinski LE, G3 (Bethesda) 2017 Jun 7;7(6):1653-1663 | J:270045 | Pathology|SARS-CoV-MA_virus | Ticam2tm1AkiTargeted |
MGI:3040184 | immune system Coronavirus infectious disease |
Gralinski LE, G3 (Bethesda) 2017 Jun 7;7(6):1653-1663 |
Timp1tm1Pds | MGI:3512125 | Targeted | Null/knockout | Savarin C, ASN Neuro 2013 Nov 26;5(5):e00127 | J:331803 | Mouse_Hepatitis_virus | Timp1tm1PdsTargeted |
Savarin C, ASN Neuro 2013 Nov 26;5(5):e00127 |
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Tlr2tm1Aki | MGI:2178675 | Targeted | Null/knockout | Zheng M, Nat Immunol 2021 Jul;22(7):829-838 | J:308903 | Pathology|SARS-CoV-2_virus | Tlr2tm1AkiTargeted |
Zheng M, Nat Immunol 2021 Jul;22(7):829-838 |
|||||||
Tlr2tm1Kir | MGI:2674036 | Targeted | Null/knockout | Yang J, Nature 2020 Jul 29;(): Khan S, bioRxiv 2021 Mar;(): | J:292665 J:303202 | SARS-CoV-2_virus|Vaccine Infection|SARS-CoV-2_virus | Tlr2tm1KirTargeted |
Yang J, Nature 2020 Jul 29;(): Khan S, bioRxiv 2021 Mar;(): |
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Tlr3tm1Aki | MGI:3690535 | Targeted | Null/knockout | MGI:3698173 MGI:6403489 | cardiovascular system immune system muscle | MP:0005385 MP:0005387 MP:0005369 | Cervantes-Barragan L, Blood 2007 Feb 1;109(3):1131-7 Imai Y, Cell 2008 Apr 18;133(2):235-49 | J:144400 J:145306 | Infection|Mouse_Hepatitis_virus|SARS-CoV_virus SARS-CoV_virus | Tlr3tm1AkiTargeted |
MGI:3698173 MGI:6403489 | cardiovascular system immune system muscle |
Cervantes-Barragan L, Blood 2007 Feb 1;109(3):1131-7 Imai Y, Cell 2008 Apr 18;133(2):235-49 |
||
Tlr3tm1Flv | MGI:2653138 | Targeted | Null/knockout | MGI:6433074 | immune system respiratory system | MP:0005387 MP:0005388 | Totura AL, mBio 2015 May 26;6(3):e00638-15 | J:288471 | Infection|SARS-CoV-MA_virus | Tlr3tm1FlvTargeted |
MGI:6433074 | immune system respiratory system |
Totura AL, mBio 2015 May 26;6(3):e00638-15 |
||
Tlr4Lps-d | MGI:1857718 | Spontaneous | Imai Y, Cell 2008 Apr 18;133(2):235-49 Khanolkar A, J Virol 2009 Sep;83(17):8946-56 | J:145306 J:153918 | SARS-CoV_virus Mouse_Hepatitis_virus|Pathology | Tlr4Lps-dSpontaneous |
Imai Y, Cell 2008 Apr 18;133(2):235-49 Khanolkar A, J Virol 2009 Sep;83(17):8946-56 |
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Tlr4lps-del | MGI:1860755 | Spontaneous | Null/knockout | Yang J, Nature 2020 Jul 29;(): | J:292665 | SARS-CoV-2_virus|Vaccine | Tlr4lps-delSpontaneous |
Yang J, Nature 2020 Jul 29;(): |
|||||||
Tlr4tm1Aki | MGI:1860885 | Targeted | Null/knockout | MGI:3588775 | homeostasis/metabolism immune system | MP:0005376 MP:0005387 | Imai Y, Cell 2008 Apr 18;133(2):235-49 Zheng M, Nat Immunol 2021 Jul;22(7):829-838 | J:145306 J:308903 | SARS-CoV_virus Pathology|SARS-CoV-2_virus | Tlr4tm1AkiTargeted |
MGI:3588775 | homeostasis/metabolism immune system |
Imai Y, Cell 2008 Apr 18;133(2):235-49 Zheng M, Nat Immunol 2021 Jul;22(7):829-838 |
||
Tlr7tm1Aki | MGI:3045662 | Targeted | Null/knockout | MGI:6403489 MGI:6403490 | immune system | MP:0005387 | Cervantes-Barragan L, Blood 2007 Feb 1;109(3):1131-7 Channappanavar R, J Clin Invest 2019 Jul 29;130():3625-3639 Zheng M, Nat Immunol 2021 Jul;22(7):829-838 | J:144400 J:288107 J:308903 | Infection|Mouse_Hepatitis_virus|SARS-CoV_virus Infection|MERS-CoV-MA_virus|Treatment Pathology|SARS-CoV-2_virus | Tlr7tm1AkiTargeted |
MGI:6403489 MGI:6403490 | immune system |
Cervantes-Barragan L, Blood 2007 Feb 1;109(3):1131-7 Channappanavar R, J Clin Invest 2019 Jul 29;130():3625-3639 Zheng M, Nat Immunol 2021 Jul;22(7):829-838 |
||
Tlr9tm1Aki | MGI:2660562 | Targeted | Null/knockout | Imai Y, Cell 2008 Apr 18;133(2):235-49 Lam LKM, Sci Transl Med 2021 Oct 20;13(616):eabj1008 | J:145306 J:325468 | SARS-CoV_virus SARS-CoV-2_virus | Tlr9tm1AkiTargeted |
Imai Y, Cell 2008 Apr 18;133(2):235-49 Lam LKM, Sci Transl Med 2021 Oct 20;13(616):eabj1008 |
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Tmem41bem1Cya | MGI:6838393 | Endonuclease-mediated | Null/knockout | MGI:6838394 | mortality/aging | MP:0010768 | Sun L, PLoS Pathog 2021 Dec;17(12):e1010113 | J:316472 | Gene|Mouse_Hepatitis_virus|SARS-CoV-2_virus | Tmem41bem1CyaEndonuclease-mediated |
MGI:6838394 | mortality/aging |
Sun L, PLoS Pathog 2021 Dec;17(12):e1010113 |
||
Tmprss2tm1(KOMP)Vlcg | MGI:4399580 | Targeted | Null/knockout|Reporter | MGI:5705124 MGI:6403636 | embryo growth/size/body immune system reproductive system respiratory system mortality/aging | MP:0005380 MP:0005378 MP:0005387 MP:0005389 MP:0005388 MP:0010768 | Iwata-Yoshikawa N, J Virol 2019 Mar 15;93(6): Mullick JB, Cell Mol Bioeng 2020 Jul 27;():1-11 | J:283077 J:294026 | MERS-CoV-MA_virus|MERS-CoV_virus|Pathology SARS-CoV-2_virus|SARS-CoV_virus | Tmprss2tm1(KOMP)VlcgTargeted |
MGI:5705124 MGI:6403636 | embryo growth/size/body immune system reproductive system respiratory system mortality/aging |
Iwata-Yoshikawa N, J Virol 2019 Mar 15;93(6): Mullick JB, Cell Mol Bioeng 2020 Jul 27;():1-11 |
||
Tnfrsf1atm1Imx | MGI:1857468 | Targeted | Null/knockout | MGI:6433775 | immune system | MP:0005387 | McDermott JE, BMC Syst Biol 2016 Sep 23;10(1):93 Xu H, Immunol Lett 2014 Mar-Apr;158(1-2):25-32 | J:288523 J:315532 | Pathology|SARS-CoV-MA_virus Mouse_Hepatitis_virus | Tnfrsf1atm1ImxTargeted |
MGI:6433775 | immune system |
McDermott JE, BMC Syst Biol 2016 Sep 23;10(1):93 Xu H, Immunol Lett 2014 Mar-Apr;158(1-2):25-32 |
||
Tnfrsf1atm1Mak | MGI:1857261 | Targeted | Null/knockout | McDermott JE, BMC Syst Biol 2016 Sep 23;10(1):93 | J:288523 | Pathology|SARS-CoV-MA_virus | Tnfrsf1atm1MakTargeted |
McDermott JE, BMC Syst Biol 2016 Sep 23;10(1):93 |
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Tnfrsf1btm1Imx | MGI:1860087 | Targeted | Null/knockout | MGI:6433775 | immune system | MP:0005387 | McDermott JE, BMC Syst Biol 2016 Sep 23;10(1):93 Xu H, Immunol Lett 2014 Mar-Apr;158(1-2):25-32 | J:288523 J:315532 | Pathology|SARS-CoV-MA_virus Mouse_Hepatitis_virus | Tnfrsf1btm1ImxTargeted |
MGI:6433775 | immune system |
McDermott JE, BMC Syst Biol 2016 Sep 23;10(1):93 Xu H, Immunol Lett 2014 Mar-Apr;158(1-2):25-32 |
||
Tnfrsf1btm1Mwm | MGI:1857262 | Targeted | Null/knockout | MGI:3580520 | cellular hematopoietic system immune system | MP:0005384 MP:0005397 MP:0005387 | McDermott JE, BMC Syst Biol 2016 Sep 23;10(1):93 | J:288523 | Pathology|SARS-CoV-MA_virus | Tnfrsf1btm1MwmTargeted |
MGI:3580520 | cellular hematopoietic system immune system |
McDermott JE, BMC Syst Biol 2016 Sep 23;10(1):93 |
||
Tnftm1Gkl | MGI:2149024 | Targeted | Null/knockout | Xu H, Immunol Lett 2014 Mar-Apr;158(1-2):25-32 | J:315532 | Mouse_Hepatitis_virus | Tnftm1GklTargeted |
Xu H, Immunol Lett 2014 Mar-Apr;158(1-2):25-32 |
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Traf6tm1.1Mpa | MGI:3836555 | Targeted | Conditional ready|No functional change | Imai Y, Cell 2008 Apr 18;133(2):235-49 | J:145306 | SARS-CoV_virus | Traf6tm1.1MpaTargeted |
Imai Y, Cell 2008 Apr 18;133(2):235-49 |
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Trem2tm1(KOMP)Vlcg | MGI:3797897 | Targeted | Null/knockout|Reporter | Hwang M, J Neuroinflammation 2022 Nov 4;19(1):267 | J:331755 | Mouse_Hepatitis_virus | Trem2tm1(KOMP)VlcgTargeted |
Hwang M, J Neuroinflammation 2022 Nov 4;19(1):267 |
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Trim55tm1Slbt | MGI:3773035 | Targeted | Null/knockout | MGI:3773039 | cardiovascular system growth/size/body immune system limbs/digits/tail muscle | MP:0005385 MP:0005378 MP:0005387 MP:0005371 MP:0005369 | Gralinski LE, PLoS Genet 2015 Oct;11(10):e1005504 | J:268979 | Infection|SARS-CoV-MA_virus | Trim55tm1SlbtTargeted |
MGI:3773039 | cardiovascular system growth/size/body immune system limbs/digits/tail muscle |
Gralinski LE, PLoS Genet 2015 Oct;11(10):e1005504 |
||
Tyrc-2J | MGI:1855985 | Spontaneous | Null/knockout | Scaglione A, Front Immunol 2021;12():719077 | J:335910 | SARS-CoV-2_virus|Treatment|Vaccine | Tyrc-2JSpontaneous |
Scaglione A, Front Immunol 2021;12():719077 |
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Usp10em2Smoc | MGI:7442004 | Endonuclease-mediated | Conditional ready | Luo Y, Signal Transduct Target Ther 2022 Jan 4;7(1):7 | J:333746 | SARS-CoV-2_virus|Vaccine | Usp10em2SmocEndonuclease-mediated |
Luo Y, Signal Transduct Target Ther 2022 Jan 4;7(1):7 |
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Usp18tm1Dez | MGI:2387336 | Targeted | Null/knockout|Reporter | MGI:5908648 | homeostasis/metabolism immune system | MP:0005376 MP:0005387 | Ma XZ, J Virol 2014 Jun;88(11):6195-204 | J:214425 | Mouse_Hepatitis_virus | Usp18tm1DezTargeted |
MGI:5908648 | homeostasis/metabolism immune system |
Ma XZ, J Virol 2014 Jun;88(11):6195-204 |
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Vhltm1Jae | MGI:2136645 | Targeted | Conditional ready|No functional change | Kotagiri P, EBioMedicine 2022 Feb 18;77():103878 | J:322643 | SARS-CoV-2_virus | Vhltm1JaeTargeted |
Kotagiri P, EBioMedicine 2022 Feb 18;77():103878 |
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Wwtr1tm1.2Hmc | MGI:7581994 | Targeted | Conditional ready | Harb H, Immunity 2021 Apr 22;(): | J:347529 | Infection | Wwtr1tm1.2HmcTargeted |
Harb H, Immunity 2021 Apr 22;(): |
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Yap1tm1.1Dupa | MGI:4819826 | Targeted | Conditional ready|No functional change | Harb H, Immunity 2021 Apr 22;(): | J:347529 | Infection | Yap1tm1.1DupaTargeted |
Harb H, Immunity 2021 Apr 22;(): |
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Yif1bem1Hawu | MGI:7408565 | Endonuclease-mediated | Null/knockout | Lin X, bioRxiv 2021 Dec;(): | J:315744 | Gene|Pathology|SARS-CoV-2_virus | Yif1bem1HawuEndonuclease-mediated |
Lin X, bioRxiv 2021 Dec;(): |
Mouse Genes Associated with Coronavirus Infection and Pathology
1-gene-symbol | 2-gene-name | 3-feature-type | 4-mgi-id | 5-short-citation | 6-jnum-id | 7-covid-tags | Gene | Gene Details | References | Keywords |
---|---|---|---|---|---|---|---|---|---|
Abl2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | protein coding gene | MGI:87860 | Williams RK, Proc Natl Acad Sci U S A 1991 Jul 1;88(13):5533-6 | J:25438 | Infection | Mouse_Hepatitis_virus | Abl2ABL proto-oncogene 2, non-receptor tyrosine kinaseprotein coding gene |
MGI | Alliance | Williams RK, Proc Natl Acad Sci U S A 1991 Jul 1;88(13):5533-6 |
Ace | angiotensin I converting enzyme | protein coding gene | MGI:87874 | Wysocki J, J Am Soc Nephrol 2020 Sep;31(9):1941-1943 | J:294060 | SARS-CoV-2_virus | Aceangiotensin I converting enzymeprotein coding gene |
MGI | Alliance | Wysocki J, J Am Soc Nephrol 2020 Sep;31(9):1941-1943 |
Ace2 | angiotensin converting enzyme 2 | protein coding gene | MGI:1917258 | Adams LE, mBio 2021 Mar 16;12(2): Bao L, Nature 2020 May 7;(): Biagioli M, bioRxiv 2021 Feb;(): Bilinska K, ACS Chem Neurosci 2020 Jun 3;11(11):1555-1562 Bilinska K, bioRxiv 2021 Apr;(): Bourgonje AR, J Pathol 2020 Jul;251(3):228-248 Brechbuhl J, bioRxiv 2021 Mar;(): Brechbuhl J, Commun Biol 2021 Jul 15;4(1):880 Chen J, Aging Cell 2020 Jun 19;(): Chen J, bioRxiv 2021 Nov;(): Choi JY, Biochem Biophys Res Commun 2020 Jul 30;528(3):413-419 Deng Q, bioRxiv 2020;(): Gao S, Front Cardiovasc Med 2023;10():1266276 Gawish R, Elife 2022 Jan 13;11():e74623 Glass WG, J Immunol 2004 Sep 15;173(6):4030-9 Gurumurthy CB, Nat Protoc 2020 Dec;15(12):3777-3787 Hennighausen L, Cell Rep 2020 Sep 29;32(13):108199 Israelow B, J Exp Med 2020 Dec 7;217(12): Jia H, Nat Commun 2020 Oct 14;11(1):5165 Jiang S, bioRxiv 2021 Aug;(): Ji H, Hypertension 2020 Aug;76(2):478-487 Johansen MD, Mucosal Immunol 2020 Aug 20;(): Koester ST, PLoS One 2021;16(3):e0248730 Kuba K, Nat Med 2005 Aug;11(8):875-9 Li C, Cell 2022 Apr 14;185(8):1389-1401.e18 Li D, J Med Virol 2022 Oct;94(10):4878-4889 Li F, Nat Commun 2021 Feb 8;12(1):866 Liu A, J Pathol 2021 Jan;253(1):17-30 Liu D, Proc Natl Acad Sci U S A 2023 Jan 24;120(4):e2202820120 Liu Y, Proc Natl Acad Sci U S A 2021 Mar 23;118(12):e2025373118 Li Y, bioRxiv 2020 Oct;(): Martin-Lopez E, eNeuro 2024 Jun;11(6):ENEURO.0106-24.2024 Mullick JB, Cell Mol Bioeng 2020 Jul 27;():1-11 Munoz-Fontela C, Nature 2020 Sep 23;(): Nakandakari-Higa S, Front Immunol 2022;13():1007080 Perico L, Sci Rep 2023 Jul 14;13(1):11392 Pinto D, bioRxiv 2020 Apr 9;(): Qiao J, Biochem Biophys Res Commun 2020 Dec 17;533(4):867-871 Qin WH, Cell Mol Gastroenterol Hepatol 2021;12(4):1514-1516.e4 Romero MJ, Front Immunol 2023;14():1241448 Sagawa T, Environ Res 2021 Apr;195():110722 Sarver DC, Biochem Biophys Res Commun 2021 Jan 29;538():92-96 Sepe S, bioRxiv 2021 Jun;(): Sepe S, EMBO Rep 2022 Feb 3;23(2):e53658 Singh A, Virol Sin 2020 Jun;35(3):290-304 Song J, J Med Virol 2020 Nov;92(11):2556-2566 Soni S, PLoS One 2021;16(2):e0247510 Sun SH, Cell Host Microbe 2020;20():1-10 Tada T, Proc Natl Acad Sci U S A 2023 Jun 6;120(23):e2303509120 Tang AT, bioRxiv 2021 Dec;(): Tang AT, PLoS Biol 2023 Feb;21(2):e3001989 Tang X, bioRxiv 2020 Oct;(): Ulrich L, bioRxiv 2021 Jun;(): van de Veerdonk FL, Elife 2020 Apr 27;9():e57555 Vergara A, Mol Cell Endocrinol 2021 Jun 1;529():111263 Viveiros A, Am J Physiol Heart Circ Physiol 2021 Jan 1;320(1):H296-H304 Vo T, bioRxiv 2020 Nov;(): Wang Q, Cell 2020 May 14;181(4):894-904.e9 Wang Y, FASEB J 2021 Mar;35(3):e21419 Winkler ES, J Virol 2022 Jan 12;96(1):e0151121 Wu X, bioRxiv 2021 Feb;(): Wu Y, Science 2020 Jun 12;368(6496):1274-1278 Wysocki J, J Am Soc Nephrol 2020 Sep;31(9):1941-1943 Xu J, Theranostics 2021;11(15):7379-7390 Yang J, Nature 2020 Jul 29;(): Ye Q, bioRxiv 2020 Nov;(): Yu W, Biochem Biophys Res Commun 2020 Dec 17;533(4):1276-1282 Zhou B, bioRxiv 2020;(): Zhou B, Nature 2021 Apr;592(7852):122-127 Zhou P, Nature 2020 Mar;579(7798):270-273 Zhu L, bioRxiv 2020 Nov;(): Ziegler CGK, Cell 2020 May 28;181(5):1016-1035.e19 | J:305729 J:287631 J:302704 J:288137 J:304622 J:300087 J:303458 J:319436 J:291430 J:315718 J:292007 J:296182 J:346048 J:318828 J:92752 J:298750 J:297407 J:291862 J:296535 J:308668 J:290256 J:295350 J:303461 J:286299 J:324335 J:339217 J:303471 J:301197 J:340364 J:303469 J:296372 J:349938 J:294026 J:295351 J:335150 J:338324 J:297123 J:299392 J:319435 J:339692 J:305462 J:309632 J:309195 J:326929 J:295349 J:300096 J:303459 J:288243 J:338414 J:315719 J:337814 J:296386 J:308620 J:291465 J:308897 J:303463 J:296710 J:291441 J:309535 J:331773 J:302150 J:290802 J:294060 J:314372 J:292665 J:296708 J:299383 J:296356 J:305777 J:291451 J:298147 J:291435 | SARS-CoV-2-MA_virus Infection | Pathology | SARS-CoV-2_virus Infection | Treatment Infection | SARS-CoV-2_virus Gene SARS-CoV-2_virus SARS-CoV-2_virus | Sex_bias SARS-CoV-2_virus | Vaccine Pathology | SARS-CoV-2-MA_virus Infection | SARS-CoV_virus MERS-CoV-MA_virus | MERS-CoV_virus | SARS-CoV-2-MA_virus | SARS-CoV-2_virus | SARS-CoV-MA_virus | SARS-CoV_virus SARS-CoV-2_virus | Treatment | VOC_B.1.1.529_Omicron SARS-CoV-2_virus | Treatment Comorbidity | Gene SARS-CoV-2_virus | VOC_B.1.351_Beta Pathology | SARS-CoV-2_virus SARS-CoV-2_virus | SARS-CoV_virus SARS-CoV-2-MA_virus | SARS-CoV-2_virus | SARS-CoV_virus Infection | SARS-CoV-2_virus | VOC_B.1.1.529_Omicron Pathology | SARS-CoV-2_virus | Treatment Gene | Infection Comorbidity MERS-CoV-MA_virus | MERS-CoV_virus | SARS-CoV-2-MA_virus | SARS-CoV-2_virus | SARS-CoV_virus Pathology | SARS-CoV-2_virus | VOC_B.1.1.529_Omicron Infection | SARS-CoV-2_virus | VOC_B.1.1.7_Alpha | VOC_B.1.351_Beta Infection SARS-CoV-2-MA_virus | SARS-CoV-2_virus | Treatment | Ace2angiotensin converting enzyme 2protein coding gene |
MGI | Alliance | Adams LE, mBio 2021 Mar 16;12(2): Bao L, Nature 2020 May 7;(): Biagioli M, bioRxiv 2021 Feb;(): Bilinska K, ACS Chem Neurosci 2020 Jun 3;11(11):1555-1562 Bilinska K, bioRxiv 2021 Apr;(): Bourgonje AR, J Pathol 2020 Jul;251(3):228-248 Brechbuhl J, bioRxiv 2021 Mar;(): Brechbuhl J, Commun Biol 2021 Jul 15;4(1):880 Chen J, Aging Cell 2020 Jun 19;(): Chen J, bioRxiv 2021 Nov;(): Choi JY, Biochem Biophys Res Commun 2020 Jul 30;528(3):413-419 Deng Q, bioRxiv 2020;(): Gao S, Front Cardiovasc Med 2023;10():1266276 Gawish R, Elife 2022 Jan 13;11():e74623 Glass WG, J Immunol 2004 Sep 15;173(6):4030-9 Gurumurthy CB, Nat Protoc 2020 Dec;15(12):3777-3787 Hennighausen L, Cell Rep 2020 Sep 29;32(13):108199 Israelow B, J Exp Med 2020 Dec 7;217(12): Jia H, Nat Commun 2020 Oct 14;11(1):5165 Jiang S, bioRxiv 2021 Aug;(): Ji H, Hypertension 2020 Aug;76(2):478-487 Johansen MD, Mucosal Immunol 2020 Aug 20;(): Koester ST, PLoS One 2021;16(3):e0248730 Kuba K, Nat Med 2005 Aug;11(8):875-9 Li C, Cell 2022 Apr 14;185(8):1389-1401.e18 Li D, J Med Virol 2022 Oct;94(10):4878-4889 Li F, Nat Commun 2021 Feb 8;12(1):866 Liu A, J Pathol 2021 Jan;253(1):17-30 Liu D, Proc Natl Acad Sci U S A 2023 Jan 24;120(4):e2202820120 Liu Y, Proc Natl Acad Sci U S A 2021 Mar 23;118(12):e2025373118 Li Y, bioRxiv 2020 Oct;(): Martin-Lopez E, eNeuro 2024 Jun;11(6):ENEURO.0106-24.2024 Mullick JB, Cell Mol Bioeng 2020 Jul 27;():1-11 Munoz-Fontela C, Nature 2020 Sep 23;(): Nakandakari-Higa S, Front Immunol 2022;13():1007080 Perico L, Sci Rep 2023 Jul 14;13(1):11392 Pinto D, bioRxiv 2020 Apr 9;(): Qiao J, Biochem Biophys Res Commun 2020 Dec 17;533(4):867-871 Qin WH, Cell Mol Gastroenterol Hepatol 2021;12(4):1514-1516.e4 Romero MJ, Front Immunol 2023;14():1241448 Sagawa T, Environ Res 2021 Apr;195():110722 Sarver DC, Biochem Biophys Res Commun 2021 Jan 29;538():92-96 Sepe S, bioRxiv 2021 Jun;(): Sepe S, EMBO Rep 2022 Feb 3;23(2):e53658 Singh A, Virol Sin 2020 Jun;35(3):290-304 Song J, J Med Virol 2020 Nov;92(11):2556-2566 Soni S, PLoS One 2021;16(2):e0247510 Sun SH, Cell Host Microbe 2020;20():1-10 Tada T, Proc Natl Acad Sci U S A 2023 Jun 6;120(23):e2303509120 Tang AT, bioRxiv 2021 Dec;(): Tang AT, PLoS Biol 2023 Feb;21(2):e3001989 Tang X, bioRxiv 2020 Oct;(): Ulrich L, bioRxiv 2021 Jun;(): van de Veerdonk FL, Elife 2020 Apr 27;9():e57555 Vergara A, Mol Cell Endocrinol 2021 Jun 1;529():111263 Viveiros A, Am J Physiol Heart Circ Physiol 2021 Jan 1;320(1):H296-H304 Vo T, bioRxiv 2020 Nov;(): Wang Q, Cell 2020 May 14;181(4):894-904.e9 Wang Y, FASEB J 2021 Mar;35(3):e21419 Winkler ES, J Virol 2022 Jan 12;96(1):e0151121 Wu X, bioRxiv 2021 Feb;(): Wu Y, Science 2020 Jun 12;368(6496):1274-1278 Wysocki J, J Am Soc Nephrol 2020 Sep;31(9):1941-1943 Xu J, Theranostics 2021;11(15):7379-7390 Yang J, Nature 2020 Jul 29;(): Ye Q, bioRxiv 2020 Nov;(): Yu W, Biochem Biophys Res Commun 2020 Dec 17;533(4):1276-1282 Zhou B, bioRxiv 2020;(): Zhou B, Nature 2021 Apr;592(7852):122-127 Zhou P, Nature 2020 Mar;579(7798):270-273 Zhu L, bioRxiv 2020 Nov;(): Ziegler CGK, Cell 2020 May 28;181(5):1016-1035.e19 |
Adar | adenosine deaminase, RNA-specific | protein coding gene | MGI:1889575 | Adamska JZ, Cell Rep 2023 Jan 31;42(1):112038 | J:333092 | Gene | VOC_B.1.351_Beta | Adaradenosine deaminase, RNA-specificprotein coding gene |
MGI | Alliance | Adamska JZ, Cell Rep 2023 Jan 31;42(1):112038 |
Adh5 | alcohol dehydrogenase 5 (class III), chi polypeptide | protein coding gene | MGI:87929 | Kim J, Front Pharmacol 2023;14():1304697 | J:343781 | SARS-CoV-2_virus | Treatment | Adh5alcohol dehydrogenase 5 (class III), chi polypeptideprotein coding gene |
MGI | Alliance | Kim J, Front Pharmacol 2023;14():1304697 |
Ahr | aryl-hydrocarbon receptor | protein coding gene | MGI:105043 | Biagioli M, bioRxiv 2021 Feb;(): Grunewald ME, J Virol 2020 Jan 17;94(3): | J:302704 J:290586 | Infection | Treatment Infection | Mouse_Hepatitis_virus | Ahraryl-hydrocarbon receptorprotein coding gene |
MGI | Alliance | Biagioli M, bioRxiv 2021 Feb;(): Grunewald ME, J Virol 2020 Jan 17;94(3): |
Aicda | activation-induced cytidine deaminase | protein coding gene | MGI:1342279 | Gregoire C, bioRxiv 2021 Dec;(): Luo Y, Signal Transduct Target Ther 2022 Jan 4;7(1):7 | J:316768 J:333746 | SARS-CoV-2_virus SARS-CoV-2_virus | Vaccine | Aicdaactivation-induced cytidine deaminaseprotein coding gene |
MGI | Alliance | Gregoire C, bioRxiv 2021 Dec;(): Luo Y, Signal Transduct Target Ther 2022 Jan 4;7(1):7 |
Aim2 | absent in melanoma 2 | protein coding gene | MGI:2686159 | Zheng M, J Biol Chem 2020 Oct 9;295(41):14040-14052 | J:298138 | Mouse_Hepatitis_virus | Aim2absent in melanoma 2protein coding gene |
MGI | Alliance | Zheng M, J Biol Chem 2020 Oct 9;295(41):14040-14052 |
Apaf1 | apoptotic peptidase activating factor 1 | protein coding gene | MGI:1306796 | Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 | J:296686 | Pathology | SARS-CoV-2_virus | Treatment | Apaf1apoptotic peptidase activating factor 1protein coding gene |
MGI | Alliance | Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 |
Apoe | apolipoprotein E | protein coding gene | MGI:88057 | Ostendorf BN, Nature 2022 Nov;611(7935):346-351 Rhea EM, Nat Neurosci 2021 Mar;24(3):368-378 | J:340480 J:305558 | Gene | SARS-CoV-2-MA_virus SARS-CoV-2_virus | Apoeapolipoprotein Eprotein coding gene |
MGI | Alliance | Ostendorf BN, Nature 2022 Nov;611(7935):346-351 Rhea EM, Nat Neurosci 2021 Mar;24(3):368-378 |
App | amyloid beta precursor protein | protein coding gene | MGI:88059 | Magusali N, bioRxiv 2021 Mar;(): | J:303205 | Comorbidity | Appamyloid beta precursor proteinprotein coding gene |
MGI | Alliance | Magusali N, bioRxiv 2021 Mar;(): |
Arl8b | ADP-ribosylation factor-like 8B | protein coding gene | MGI:1914416 | Ghosh S, Cell 2020 Dec 10;183(6):1520-1535.e14 | J:302472 | Infection | Mouse_Hepatitis_virus | Arl8bADP-ribosylation factor-like 8Bprotein coding gene |
MGI | Alliance | Ghosh S, Cell 2020 Dec 10;183(6):1520-1535.e14 |
Atg5 | autophagy related 5 | protein coding gene | MGI:1277186 | de Almeida L, Sci Adv 2022 Sep 16;8(37):eabo5400 Zhao Z, Autophagy 2007 Nov-Dec;3(6):581-5 | J:331763 J:282479 | SARS-CoV-2_virus Mouse_Hepatitis_virus | Atg5autophagy related 5protein coding gene |
MGI | Alliance | de Almeida L, Sci Adv 2022 Sep 16;8(37):eabo5400 Zhao Z, Autophagy 2007 Nov-Dec;3(6):581-5 |
B2m | beta-2 microglobulin | protein coding gene | MGI:88127 | Brentville VA, bioRxiv 2021 Jun;(): Houtman JJ, J Neurovirol 1996 APR;2(2):101-110 Lavi E, Pathobiology 1999 Mar-Apr;67(2):75-83 | J:308658 J:33974 J:54035 | SARS-CoV-2_virus | Vaccine Mouse_Hepatitis_virus Mouse_Hepatitis_virus | Pathology | B2mbeta-2 microglobulinprotein coding gene |
MGI | Alliance | Brentville VA, bioRxiv 2021 Jun;(): Houtman JJ, J Neurovirol 1996 APR;2(2):101-110 Lavi E, Pathobiology 1999 Mar-Apr;67(2):75-83 |
Batf3 | basic leucine zipper transcription factor, ATF-like 3 | protein coding gene | MGI:1925491 | Ndeupen S, bioRxiv 2021 Aug;(): Ngo VL, Cell Host Microbe 2024 Jan 23;(): | J:308580 J:345954 | SARS-CoV-2_virus | Vaccine Infection | MERS-CoV-MA_virus | Batf3basic leucine zipper transcription factor, ATF-like 3protein coding gene |
MGI | Alliance | Ndeupen S, bioRxiv 2021 Aug;(): Ngo VL, Cell Host Microbe 2024 Jan 23;(): |
Bcl2l1 | BCL2-like 1 | protein coding gene | MGI:88139 | Yang Y, Biochem J 2005 Nov 15;392(Pt 1):135-43 | J:287050 | SARS-CoV_virus | Bcl2l1BCL2-like 1protein coding gene |
MGI | Alliance | Yang Y, Biochem J 2005 Nov 15;392(Pt 1):135-43 |
Bcl2l12 | BCL2 like 12 | protein coding gene | MGI:1922986 | Daffis S, Nature 2010 Nov 18;468(7322):452-6 Imai Y, Cell 2008 Apr 18;133(2):235-49 | J:187561 J:145306 | Mouse_Hepatitis_virus SARS-CoV_virus | Bcl2l12BCL2 like 12protein coding gene |
MGI | Alliance | Daffis S, Nature 2010 Nov 18;468(7322):452-6 Imai Y, Cell 2008 Apr 18;133(2):235-49 |
Bcl6 | B cell leukemia/lymphoma 6 | protein coding gene | MGI:107187 | Chen JS, bioRxiv 2021 Jun;(): | J:308655 | SARS-CoV-2_virus | VOC_B.1.351_Beta | Bcl6B cell leukemia/lymphoma 6protein coding gene |
MGI | Alliance | Chen JS, bioRxiv 2021 Jun;(): |
Bsg | basigin | protein coding gene | MGI:88208 | Geng J, bioRxiv 2021 May;(): Qiao J, Biochem Biophys Res Commun 2020 Dec 17;533(4):867-871 | J:308748 J:299392 | SARS-CoV-2_virus Gene | Bsgbasiginprotein coding gene |
MGI | Alliance | Geng J, bioRxiv 2021 May;(): Qiao J, Biochem Biophys Res Commun 2020 Dec 17;533(4):867-871 |
C1qa | complement component 1, q subcomponent, alpha polypeptide | protein coding gene | MGI:88223 | Ngo VL, Cell Host Microbe 2024 Jan 23;(): | J:345954 | Infection | MERS-CoV-MA_virus | C1qacomplement component 1, q subcomponent, alpha polypeptideprotein coding gene |
MGI | Alliance | Ngo VL, Cell Host Microbe 2024 Jan 23;(): |
C3 | complement component 3 | protein coding gene | MGI:88227 | Gralinski LE, mBio 2018 Oct 9;9(5): | J:286325 | Pathology | SARS-CoV-MA_virus | C3complement component 3protein coding gene |
MGI | Alliance | Gralinski LE, mBio 2018 Oct 9;9(5): |
C4b | complement C4B (Chido blood group) | protein coding gene | MGI:88228 | Gralinski LE, mBio 2018 Oct 9;9(5): | J:286325 | Pathology | SARS-CoV-MA_virus | C4bcomplement C4B (Chido blood group)protein coding gene |
MGI | Alliance | Gralinski LE, mBio 2018 Oct 9;9(5): |
C5ar1 | complement component 5a receptor 1 | protein coding gene | MGI:88232 | Carvelli J, Nature 2020 Jul 29;(): Jiang Y, Viruses 2019 Jan 9;11(1): | J:291890 J:295108 | Pathology | SARS-CoV-2_virus | Treatment MERS-CoV_virus | C5ar1complement component 5a receptor 1protein coding gene |
MGI | Alliance | Carvelli J, Nature 2020 Jul 29;(): Jiang Y, Viruses 2019 Jan 9;11(1): |
Casp1 | caspase 1 | protein coding gene | MGI:96544 | Duhalde Vega M, Sci Adv 2022 Sep 23;8(38):eabn6545 Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 Kim E, Proc Natl Acad Sci U S A 2021 Aug 24;118(34):e2102435118 Wu J, Immunity 2021 Nov 9;54(11):2632-2649.e6 Yang J, Nature 2020 Jul 29;(): Zalinger ZB, J Neurovirol 2017 Dec;23(6):845-854 Zheng M, J Biol Chem 2020 Oct 9;295(41):14040-14052 | J:331762 J:296686 J:313327 J:323769 J:292665 J:331829 J:298138 | Mouse_Hepatitis_virus Pathology | SARS-CoV-2_virus | Treatment SARS-CoV-2_virus | Vaccine Gene | Pathology | Casp1caspase 1protein coding gene |
MGI | Alliance | Duhalde Vega M, Sci Adv 2022 Sep 23;8(38):eabn6545 Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 Kim E, Proc Natl Acad Sci U S A 2021 Aug 24;118(34):e2102435118 Wu J, Immunity 2021 Nov 9;54(11):2632-2649.e6 Yang J, Nature 2020 Jul 29;(): Zalinger ZB, J Neurovirol 2017 Dec;23(6):845-854 Zheng M, J Biol Chem 2020 Oct 9;295(41):14040-14052 |
Casp3 | caspase 3 | protein coding gene | MGI:107739 | Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 | J:296686 | Pathology | SARS-CoV-2_virus | Treatment | Casp3caspase 3protein coding gene |
MGI | Alliance | Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 |
Casp4 | caspase 4, apoptosis-related cysteine peptidase | protein coding gene | MGI:107700 | Eltobgy M, bioRxiv 2021;(): Eltobgy MM, Proc Natl Acad Sci U S A 2022 May 24;119(21):e2202012119 Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 Zheng M, J Biol Chem 2020 Oct 9;295(41):14040-14052 | J:311911 J:331823 J:296686 J:298138 | Gene | SARS-CoV-2-MA_virus Gene | SARS-CoV-2-MA_virus | SARS-CoV-2_virus Pathology | SARS-CoV-2_virus | Treatment Mouse_Hepatitis_virus | Casp4caspase 4, apoptosis-related cysteine peptidaseprotein coding gene |
MGI | Alliance | Eltobgy M, bioRxiv 2021;(): Eltobgy MM, Proc Natl Acad Sci U S A 2022 May 24;119(21):e2202012119 Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 Zheng M, J Biol Chem 2020 Oct 9;295(41):14040-14052 |
Casp7 | caspase 7 | protein coding gene | MGI:109383 | Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 | J:296686 | Pathology | SARS-CoV-2_virus | Treatment | Casp7caspase 7protein coding gene |
MGI | Alliance | Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 |
Casp8 | caspase 8 | protein coding gene | MGI:1261423 | Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 Zheng M, J Biol Chem 2020 Oct 9;295(41):14040-14052 | J:296686 J:298138 | Pathology | SARS-CoV-2_virus | Treatment Mouse_Hepatitis_virus | Casp8caspase 8protein coding gene |
MGI | Alliance | Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 Zheng M, J Biol Chem 2020 Oct 9;295(41):14040-14052 |
Ccl2 | C-C motif chemokine ligand 2 | protein coding gene | MGI:98259 | Glass WG, J Immunol 2004 Sep 15;173(6):4030-9 Held KS, Virology 2004 Nov 24;329(2):251-60 | J:92752 J:102446 | Infection | SARS-CoV_virus Infection | Mouse_Hepatitis_virus | Ccl2C-C motif chemokine ligand 2protein coding gene |
MGI | Alliance | Glass WG, J Immunol 2004 Sep 15;173(6):4030-9 Held KS, Virology 2004 Nov 24;329(2):251-60 |
Ccl3 | C-C motif chemokine ligand 3 | protein coding gene | MGI:98260 | Glass WG, J Immunol 2004 Sep 15;173(6):4030-9 | J:92752 | Infection | SARS-CoV_virus | Ccl3C-C motif chemokine ligand 3protein coding gene |
MGI | Alliance | Glass WG, J Immunol 2004 Sep 15;173(6):4030-9 |
Ccl5 | C-C motif chemokine ligand 5 | protein coding gene | MGI:98262 | Glass WG, J Immunol 2004 Apr 1;172(7):4018-25 Glass WG, J Immunol 2004 Sep 15;173(6):4030-9 | J:88677 J:92752 | Mouse_Hepatitis_virus Infection | SARS-CoV_virus | Ccl5C-C motif chemokine ligand 5protein coding gene |
MGI | Alliance | Glass WG, J Immunol 2004 Apr 1;172(7):4018-25 Glass WG, J Immunol 2004 Sep 15;173(6):4030-9 |
Ccr1 | C-C motif chemokine receptor 1 | protein coding gene | MGI:104618 | Sheahan T, PLoS Pathog 2008 Dec;4(12):e1000240 | J:162707 | Pathology | SARS-CoV-MA_virus | Ccr1C-C motif chemokine receptor 1protein coding gene |
MGI | Alliance | Sheahan T, PLoS Pathog 2008 Dec;4(12):e1000240 |
Ccr2 | C-C motif chemokine receptor 2 | protein coding gene | MGI:106185 | Chen BP, J Immunol 2001 Oct 15;167(8):4585-92 Glass WG, Virology 2001 Sep 15;288(1):8-17 Held KS, Virology 2004 Nov 24;329(2):251-60 Sheahan T, PLoS Pathog 2008 Dec;4(12):e1000240 Vanderheiden A, bioRxiv 2021 May;(): Vanderheiden A, mBio 2021 Nov 9;():e0274921 | J:106738 J:102561 J:102446 J:162707 J:308718 J:317454 | Mouse_Hepatitis_virus | Pathology Mouse_Hepatitis_virus Infection | Mouse_Hepatitis_virus Pathology | SARS-CoV-MA_virus SARS-CoV-2-MA_virus | SARS-CoV-2_virus | VOC_B.1.351_Beta Infection | SARS-CoV-2-MA_virus | VOC_B.1.351_Beta | Ccr2C-C motif chemokine receptor 2protein coding gene |
MGI | Alliance | Chen BP, J Immunol 2001 Oct 15;167(8):4585-92 Glass WG, Virology 2001 Sep 15;288(1):8-17 Held KS, Virology 2004 Nov 24;329(2):251-60 Sheahan T, PLoS Pathog 2008 Dec;4(12):e1000240 Vanderheiden A, bioRxiv 2021 May;(): Vanderheiden A, mBio 2021 Nov 9;():e0274921 |
Ccr5 | C-C motif chemokine receptor 5 | protein coding gene | MGI:107182 | Sheahan T, PLoS Pathog 2008 Dec;4(12):e1000240 | J:162707 | Pathology | SARS-CoV-MA_virus | Ccr5C-C motif chemokine receptor 5protein coding gene |
MGI | Alliance | Sheahan T, PLoS Pathog 2008 Dec;4(12):e1000240 |
Ccr9 | C-C motif chemokine receptor 9 | protein coding gene | MGI:1341902 | Schafer A, bioRxiv 2021 May;(): Schafer A, mBio 2022 Aug 30;13(4):e0145422 | J:308730 J:327836 | Pathology | SARS-CoV-2-MA_virus | SARS-CoV-2_virus | SARS-CoV-MA_virus | SARS-CoV_virus SARS-CoV-2-MA_virus | SARS-CoV-MA_virus | Ccr9C-C motif chemokine receptor 9protein coding gene |
MGI | Alliance | Schafer A, bioRxiv 2021 May;(): Schafer A, mBio 2022 Aug 30;13(4):e0145422 |
Cd19 | CD19 antigen | protein coding gene | MGI:88319 | Atkinson JR, J Virol 2017 Dec 1;91(23): Cervantes-Barragan L, J Immunol 2009 Jan 15;182(2):1099-106 Kotagiri P, EBioMedicine 2022 Feb 18;77():103878 Luo Y, Signal Transduct Target Ther 2022 Jan 4;7(1):7 Sarden N, Sci Transl Med 2022 Dec 7;14(674):eabq6682 | J:253411 J:143484 J:322643 J:333746 J:336666 | Mouse_Hepatitis_virus SARS-CoV-2_virus SARS-CoV-2_virus | Vaccine Comorbidity | SARS-CoV-2_virus | Cd19CD19 antigenprotein coding gene |
MGI | Alliance | Atkinson JR, J Virol 2017 Dec 1;91(23): Cervantes-Barragan L, J Immunol 2009 Jan 15;182(2):1099-106 Kotagiri P, EBioMedicine 2022 Feb 18;77():103878 Luo Y, Signal Transduct Target Ther 2022 Jan 4;7(1):7 Sarden N, Sci Transl Med 2022 Dec 7;14(674):eabq6682 |
Cd274 | CD274 antigen | protein coding gene | MGI:1926446 | Phares TW, J Immunol 2009 May 1;182(9):5430-8 Phares TW, J Immunol 2010 Nov 1;185(9):5607-18 Phares TW, J Neuroinflammation 2012 Dec 14;9():269 | J:147948 J:165192 J:331800 | Mouse_Hepatitis_virus Gene | Mouse_Hepatitis_virus | Cd274CD274 antigenprotein coding gene |
MGI | Alliance | Phares TW, J Immunol 2009 May 1;182(9):5430-8 Phares TW, J Immunol 2010 Nov 1;185(9):5607-18 Phares TW, J Neuroinflammation 2012 Dec 14;9():269 |
Cd4 | CD4 antigen | protein coding gene | MGI:88335 | Brentville VA, bioRxiv 2021 Jun;(): Chakravarty D, J Virol 2020 Jul 1;94(14): Heemskerk MH, Eur J Immunol 1995 Apr;25(4):1109-12 Yang J, Nature 2020 Jul 29;(): | J:308658 J:290222 J:112983 J:292665 | SARS-CoV-2_virus | Vaccine Mouse_Hepatitis_virus | Pathology Mouse_Hepatitis_virus | Cd4CD4 antigenprotein coding gene |
MGI | Alliance | Brentville VA, bioRxiv 2021 Jun;(): Chakravarty D, J Virol 2020 Jul 1;94(14): Heemskerk MH, Eur J Immunol 1995 Apr;25(4):1109-12 Yang J, Nature 2020 Jul 29;(): |
Cd46 | CD46 antigen, complement regulatory protein | protein coding gene | MGI:1203290 | Lu M, Proc Natl Acad Sci U S A 2021 Mar 23;118(12):e2026153118 | J:303467 | SARS-CoV-2_virus | Vaccine | Cd46CD46 antigen, complement regulatory proteinprotein coding gene |
MGI | Alliance | Lu M, Proc Natl Acad Sci U S A 2021 Mar 23;118(12):e2026153118 |
Cd47 | CD47 antigen (Rh-related antigen, integrin-associated signal transducer) | protein coding gene | MGI:96617 | Tal MC, mBio 2020 Jun 23;11(3): Wenzek C, iScience 2022 Dec 22;25(12):105540 | J:291450 J:331693 | SARS-CoV-2_virus | Cd47CD47 antigen (Rh-related antigen, integrin-associated signal transducer)protein coding gene |
MGI | Alliance | Tal MC, mBio 2020 Jun 23;11(3): Wenzek C, iScience 2022 Dec 22;25(12):105540 |
Cd74 | CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) | protein coding gene | MGI:96534 | Bruchez A, Science 2020 Oct 9;370(6513):241-247 | J:297334 | Gene | Cd74CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)protein coding gene |
MGI | Alliance | |
Cd79a | CD79A antigen (immunoglobulin-associated alpha) | protein coding gene | MGI:101774 | Kotagiri P, EBioMedicine 2022 Feb 18;77():103878 | J:322643 | SARS-CoV-2_virus | Cd79aCD79A antigen (immunoglobulin-associated alpha)protein coding gene |
MGI | Alliance | Kotagiri P, EBioMedicine 2022 Feb 18;77():103878 |
Cd8a | CD8 subunit alpha | protein coding gene | MGI:88346 | Yang J, Nature 2020 Jul 29;(): | J:292665 | SARS-CoV-2_virus | Vaccine | Cd8aCD8 subunit alphaprotein coding gene |
MGI | Alliance | Yang J, Nature 2020 Jul 29;(): |
Cd9 | CD9 antigen | protein coding gene | MGI:88348 | Earnest JT, PLoS Pathog 2017 Jul;13(7):e1006546 | J:246218 | Infection | MERS-CoV_virus | Cd9CD9 antigenprotein coding gene |
MGI | Alliance | Earnest JT, PLoS Pathog 2017 Jul;13(7):e1006546 |
Ceacam1 | CEA cell adhesion molecule 1 | protein coding gene | MGI:1347245 | Blau DM, J Virol 2001 Sep;75(17):8173-86 Dveksler GS, J Virol 1991 Dec;65(12):6881-91 Dveksler GS, J Virol 1993 Jan;67(1):1-8 Hemmila E, J Virol 2004 Sep;78(18):10156-65 Hirai A, J Virol 2010 Jul;84(13):6654-66 Miura TA, J Virol 2008 Jan;82(2):755-63 Nedellec P, J Virol 1994 Jul;68(7):4525-37 Peng G, J Biol Chem 2017 Feb 10;292(6):2174-2181 Peng G, Proc Natl Acad Sci U S A 2011 Jun 28;108(26):10696-701 Shang J, PLoS Pathog 2020 Mar;16(3):e1008392 Williams RK, Proc Natl Acad Sci U S A 1991 Jul 1;88(13):5533-6 Yokomori K, J Virol 1992 Dec;66(12):6931-8 | J:70815 J:701 J:92495 J:92376 J:198335 J:130131 J:18755 J:240703 J:173546 J:296119 J:25438 J:3241 | Infection | Mouse_Hepatitis_virus Mouse_Hepatitis_virus | Ceacam1CEA cell adhesion molecule 1protein coding gene |
MGI | Alliance | Blau DM, J Virol 2001 Sep;75(17):8173-86 Dveksler GS, J Virol 1991 Dec;65(12):6881-91 Dveksler GS, J Virol 1993 Jan;67(1):1-8 Hemmila E, J Virol 2004 Sep;78(18):10156-65 Hirai A, J Virol 2010 Jul;84(13):6654-66 Miura TA, J Virol 2008 Jan;82(2):755-63 Nedellec P, J Virol 1994 Jul;68(7):4525-37 Peng G, J Biol Chem 2017 Feb 10;292(6):2174-2181 Peng G, Proc Natl Acad Sci U S A 2011 Jun 28;108(26):10696-701 Shang J, PLoS Pathog 2020 Mar;16(3):e1008392 Williams RK, Proc Natl Acad Sci U S A 1991 Jul 1;88(13):5533-6 Yokomori K, J Virol 1992 Dec;66(12):6931-8 |
Ceacam2 | CEA cell adhesion molecule 2 | protein coding gene | MGI:1347246 | Hirai A, J Virol 2010 Jul;84(13):6654-66 Nedellec P, J Virol 1994 Jul;68(7):4525-37 | J:198335 J:18755 | Infection | Mouse_Hepatitis_virus | Ceacam2CEA cell adhesion molecule 2protein coding gene |
MGI | Alliance | Hirai A, J Virol 2010 Jul;84(13):6654-66 Nedellec P, J Virol 1994 Jul;68(7):4525-37 |
Ces1c | carboxylesterase 1C | protein coding gene | MGI:95420 | Martinez DR, bioRxiv 2021 Jan;(): Pruijssers AJ, Cell Rep 2020 Jul 21;32(3):107940 Sheahan TP, Nat Commun 2020 Jan 10;11(1):222 Sheahan TP, Sci Transl Med 2017 Jun 28;9(396): Zhu C, Nat Commun 2022 Aug 3;13(1):4503 | J:302135 J:298752 J:286402 J:286362 J:335969 | SARS-CoV-2-MA_virus | SARS-CoV-2_virus | Treatment MERS-CoV_virus | Treatment MERS-CoV_virus | SARS-CoV_virus | Treatment SARS-CoV-2_virus | Treatment | Ces1ccarboxylesterase 1Cprotein coding gene |
MGI | Alliance | Martinez DR, bioRxiv 2021 Jan;(): Pruijssers AJ, Cell Rep 2020 Jul 21;32(3):107940 Sheahan TP, Nat Commun 2020 Jan 10;11(1):222 Sheahan TP, Sci Transl Med 2017 Jun 28;9(396): Zhu C, Nat Commun 2022 Aug 3;13(1):4503 |
Cfb | complement factor B | protein coding gene | MGI:105975 | Gralinski LE, mBio 2018 Oct 9;9(5): | J:286325 | Pathology | SARS-CoV-MA_virus | Cfbcomplement factor Bprotein coding gene |
MGI | Alliance | Gralinski LE, mBio 2018 Oct 9;9(5): |
Ch25h | cholesterol 25-hydroxylase | protein coding gene | MGI:1333869 | Fessler MB, Am J Respir Cell Mol Biol 2023 Dec;69(6):638-648 | J:343658 | SARS-CoV-2_virus | Ch25hcholesterol 25-hydroxylaseprotein coding gene |
MGI | Alliance | Fessler MB, Am J Respir Cell Mol Biol 2023 Dec;69(6):638-648 |
Ciita | class II transactivator | protein coding gene | MGI:108445 | Bruchez A, Science 2020 Oct 9;370(6513):241-247 Chen JS, bioRxiv 2021 Jun;(): | J:297334 J:308655 | Gene SARS-CoV-2_virus | VOC_B.1.351_Beta | Ciitaclass II transactivatorprotein coding gene |
MGI | Alliance | Bruchez A, Science 2020 Oct 9;370(6513):241-247 Chen JS, bioRxiv 2021 Jun;(): |
Cmpk2 | cytidine/uridine monophosphate kinase 2 | protein coding gene | MGI:99830 | Xian H, Immunity 2021 Jul 13;54(7):1463-1477.e11 | J:308159 | Pathology | SARS-CoV-2_virus | Treatment | Cmpk2cytidine/uridine monophosphate kinase 2protein coding gene |
MGI | Alliance | Xian H, Immunity 2021 Jul 13;54(7):1463-1477.e11 |
Col1a1 | collagen, type I, alpha 1 | protein coding gene | MGI:88467 | Miguel V, Redox Biol 2023 Dec;68():102957 | J:343262 | Treatment | Col1a1collagen, type I, alpha 1protein coding gene |
MGI | Alliance | |
Commd10 | COMM domain containing 10 | protein coding gene | MGI:1916706 | Pfaender S, Nat Microbiol 2020 Jul 23;(): | J:291868 | Gene | HCoV-229E_virus | HCoV-OC43_virus | MERS-CoV_virus | Mouse_Hepatitis_virus | SARS-CoV-2_virus | SARS-CoV_virus | Commd10COMM domain containing 10protein coding gene |
MGI | Alliance | Pfaender S, Nat Microbiol 2020 Jul 23;(): |
Csf1 | colony stimulating factor 1 (macrophage) | protein coding gene | MGI:1339753 | Sefik E, bioRxiv 2021;(): | J:311907 | SARS-CoV-2_virus | Csf1colony stimulating factor 1 (macrophage)protein coding gene |
MGI | Alliance | Sefik E, bioRxiv 2021;(): |
Csf2 | colony stimulating factor 2 (granulocyte-macrophage) | protein coding gene | MGI:1339752 | Ngo VL, Cell Host Microbe 2024 Jan 23;(): | J:345954 | Infection | MERS-CoV-MA_virus | Csf2colony stimulating factor 2 (granulocyte-macrophage)protein coding gene |
MGI | Alliance | Ngo VL, Cell Host Microbe 2024 Jan 23;(): |
Ctnnb1 | catenin beta 1 | protein coding gene | MGI:88276 | Harb H, Immunity 2021 Apr 22;(): | J:347529 | Infection | Ctnnb1catenin beta 1protein coding gene |
MGI | Alliance | Harb H, Immunity 2021 Apr 22;(): |
Cx3cr1 | C-X3-C motif chemokine receptor 1 | protein coding gene | MGI:1333815 | Verma AK, mBio 2021 Oct 26;12(5):e0196921 Wheeler DL, J Clin Invest 2018 Mar 1;128(3):931-943 | J:313438 J:291614 | Mouse_Hepatitis_virus | Cx3cr1C-X3-C motif chemokine receptor 1protein coding gene |
MGI | Alliance | Verma AK, mBio 2021 Oct 26;12(5):e0196921 Wheeler DL, J Clin Invest 2018 Mar 1;128(3):931-943 |
Cxcl10 | C-X-C motif chemokine ligand 10 | protein coding gene | MGI:1352450 | Callahan V, Viruses 2021 Jun 3;13(6): Glass WG, J Immunol 2004 Sep 15;173(6):4030-9 Stiles LN, J Immunol 2006 Dec 15;177(12):8372-80 | J:335906 J:92752 J:140673 | Infection | Pathology | SARS-CoV-2_virus Infection | SARS-CoV_virus Mouse_Hepatitis_virus | Cxcl10C-X-C motif chemokine ligand 10protein coding gene |
MGI | Alliance | Callahan V, Viruses 2021 Jun 3;13(6): Glass WG, J Immunol 2004 Sep 15;173(6):4030-9 Stiles LN, J Immunol 2006 Dec 15;177(12):8372-80 |
Cxcl13 | C-X-C motif chemokine ligand 13 | protein coding gene | MGI:1888499 | Phares TW, Brain Behav Immun 2016 May;54():128-139 | J:316468 | Mouse_Hepatitis_virus | Cxcl13C-X-C motif chemokine ligand 13protein coding gene |
MGI | Alliance | Phares TW, Brain Behav Immun 2016 May;54():128-139 |
Cxcl5 | C-X-C motif chemokine ligand 5 | protein coding gene | MGI:1096868 | Liang Y, Zool Res 2020 Oct 12;():1-29 | J:296738 | Infection | Pathology | SARS-CoV-2_virus | Cxcl5C-X-C motif chemokine ligand 5protein coding gene |
MGI | Alliance | Liang Y, Zool Res 2020 Oct 12;():1-29 |
Cxcl9 | C-X-C motif chemokine ligand 9 | protein coding gene | MGI:1352449 | Callahan V, Viruses 2021 Jun 3;13(6): Glass WG, J Immunol 2004 Sep 15;173(6):4030-9 | J:335906 J:92752 | Infection | Pathology | SARS-CoV-2_virus Infection | SARS-CoV_virus | Cxcl9C-X-C motif chemokine ligand 9protein coding gene |
MGI | Alliance | Callahan V, Viruses 2021 Jun 3;13(6): Glass WG, J Immunol 2004 Sep 15;173(6):4030-9 |
Cxcr3 | C-X-C motif chemokine receptor 3 | protein coding gene | MGI:1277207 | McDermott JE, BMC Syst Biol 2016 Sep 23;10(1):93 | J:288523 | Pathology | SARS-CoV-MA_virus | Cxcr3C-X-C motif chemokine receptor 3protein coding gene |
MGI | Alliance | McDermott JE, BMC Syst Biol 2016 Sep 23;10(1):93 |
Cxcr6 | C-X-C motif chemokine receptor 6 | protein coding gene | MGI:1934582 | Schafer A, mBio 2022 Aug 30;13(4):e0145422 | J:327836 | SARS-CoV-2-MA_virus | SARS-CoV-MA_virus | Cxcr6C-X-C motif chemokine receptor 6protein coding gene |
MGI | Alliance | Schafer A, mBio 2022 Aug 30;13(4):e0145422 |
Dpp4 | dipeptidylpeptidase 4 | protein coding gene | MGI:94919 | Brunaugh AD, PLoS One 2021;16(2):e0246803 Channappanavar R, J Clin Invest 2019 Jul 29;130():3625-3639 Cockrell AS, Nat Microbiol 2016 Nov 28;2():16226 Coleman CM, J Virol 2017 Jan 01;91(1): Du L, Nat Commun 2016 Nov 22;7():13473 Earnest JT, PLoS Pathog 2017 Jul;13(7):e1006546 Gutierrez-Alvarez J, J Virol 2021 Jan 13;95(3): Gutierrez-Alvarez J, Proc Natl Acad Sci U S A 2021 Oct 26;118(43):e2111075118 Iwata-Yoshikawa N, J Virol 2019 Mar 15;93(6): Jia W, Emerg Microbes Infect 2019;8(1):760-772 Johansen MD, Mucosal Immunol 2020 Aug 20;(): Kulcsar KA, JCI Insight 2019 Oct 17;4(20): Leist SR, Methods Mol Biol 2020;2099():137-159 Leist SR, PLoS One 2019;14(7):e0220126 Li K, mBio 2020 Apr 7;11(2): Li K, Proc Natl Acad Sci U S A 2017 Apr 11;114(15):E3119-E3128 Menachery VD, mBio 2017 Aug 22;8(4): Munster VJ, NPJ Vaccines 2017;2():28 Pascal KE, Proc Natl Acad Sci U S A 2015 Jul 14;112(28):8738-43 Raha AA, Biosci Rep 2020 Dec 23;40(12): Sheahan TP, Nat Commun 2020 Jan 10;11(1):222 Sheahan TP, Sci Transl Med 2020 Apr 29;12(541): Singh A, Virol Sin 2020 Jun;35(3):290-304 Tai W, Virology 2016 Dec;499():375-382 Wong L-YR, mBio 2023 Oct 26;14(6):e0247623 Xia LY, Nat Commun 2024 Feb 5;15(1):1048 Yuan L, Emerg Microbes Infect 2020 Dec;9(1):949-961 Zheng J, J Clin Invest 2021 Jun 1;131(11): | J:302248 J:288107 J:279834 J:238079 J:291617 J:246218 J:300138 J:315826 J:286321 J:286329 J:295350 J:286238 J:285962 J:279723 J:287921 J:242025 J:287147 J:292834 J:223728 J:313516 J:286402 J:286320 J:295349 J:331809 J:343780 J:353426 J:300104 J:311966 | MERS-CoV_virus | SARS-CoV-2_virus | Treatment Infection | MERS-CoV-MA_virus | Treatment MERS-CoV_virus MERS-CoV_virus | Pathology MERS-CoV_virus | Vaccine Infection | MERS-CoV_virus MERS-CoV-MA_virus | MERS-CoV_virus | Vaccine MERS-CoV-MA_virus | MERS-CoV_virus | SARS-CoV-2-MA_virus | SARS-CoV-2_virus | SARS-CoV-MA_virus | SARS-CoV_virus Comorbidity | MERS-CoV_virus | Pathology Infection | MERS-CoV-MA_virus | Pathology Infection | MERS-CoV_virus | Treatment Gene MERS-CoV_virus | Treatment MERS-CoV_virus | SARS-CoV-2_virus | SARS-CoV-MA_virus | SARS-CoV_virus | Treatment MERS-CoV-MA_virus | MERS-CoV_virus | SARS-CoV-2-MA_virus | SARS-CoV-2_virus | SARS-CoV_virus MERS-CoV-MA_virus | Pathology | SARS-CoV-2_virus Infection MERS-CoV_virus | SARS-CoV-2_virus | SARS-CoV_virus Comorbidity | MERS-CoV_virus | Dpp4dipeptidylpeptidase 4protein coding gene |
MGI | Alliance | Brunaugh AD, PLoS One 2021;16(2):e0246803 Channappanavar R, J Clin Invest 2019 Jul 29;130():3625-3639 Cockrell AS, Nat Microbiol 2016 Nov 28;2():16226 Coleman CM, J Virol 2017 Jan 01;91(1): Du L, Nat Commun 2016 Nov 22;7():13473 Earnest JT, PLoS Pathog 2017 Jul;13(7):e1006546 Gutierrez-Alvarez J, J Virol 2021 Jan 13;95(3): Gutierrez-Alvarez J, Proc Natl Acad Sci U S A 2021 Oct 26;118(43):e2111075118 Iwata-Yoshikawa N, J Virol 2019 Mar 15;93(6): Jia W, Emerg Microbes Infect 2019;8(1):760-772 Johansen MD, Mucosal Immunol 2020 Aug 20;(): Kulcsar KA, JCI Insight 2019 Oct 17;4(20): Leist SR, Methods Mol Biol 2020;2099():137-159 Leist SR, PLoS One 2019;14(7):e0220126 Li K, mBio 2020 Apr 7;11(2): Li K, Proc Natl Acad Sci U S A 2017 Apr 11;114(15):E3119-E3128 Menachery VD, mBio 2017 Aug 22;8(4): Munster VJ, NPJ Vaccines 2017;2():28 Pascal KE, Proc Natl Acad Sci U S A 2015 Jul 14;112(28):8738-43 Raha AA, Biosci Rep 2020 Dec 23;40(12): Sheahan TP, Nat Commun 2020 Jan 10;11(1):222 Sheahan TP, Sci Transl Med 2020 Apr 29;12(541): Singh A, Virol Sin 2020 Jun;35(3):290-304 Tai W, Virology 2016 Dec;499():375-382 Wong L-YR, mBio 2023 Oct 26;14(6):e0247623 Xia LY, Nat Commun 2024 Feb 5;15(1):1048 Yuan L, Emerg Microbes Infect 2020 Dec;9(1):949-961 Zheng J, J Clin Invest 2021 Jun 1;131(11): |
Dyrk1a | dual-specificity tyrosine phosphorylation regulated kinase 1a | protein coding gene | MGI:1330299 | Strine MS, PLoS Biol 2023 Jun;21(6):e3002097 | J:341033 | Gene | MERS-CoV_virus | SARS-CoV-2_virus | SARS-CoV_virus | Dyrk1adual-specificity tyrosine phosphorylation regulated kinase 1aprotein coding gene |
MGI | Alliance | Strine MS, PLoS Biol 2023 Jun;21(6):e3002097 |
Ebi3 | Epstein-Barr virus induced gene 3 | protein coding gene | MGI:1354171 | Tirotta E, J Neuroimmunol 2013 Jan 15;254(1-2):110-6 | J:286951 | Infection | Mouse_Hepatitis_virus | Ebi3Epstein-Barr virus induced gene 3protein coding gene |
MGI | Alliance | Tirotta E, J Neuroimmunol 2013 Jan 15;254(1-2):110-6 |
Edil3 | EGF-like repeats and discoidin I-like domains 3 | protein coding gene | MGI:1329025 | Tang AT, bioRxiv 2021 Dec;(): Tang AT, PLoS Biol 2023 Feb;21(2):e3001989 | J:315719 J:337814 | Pathology | SARS-CoV-2_virus Pathology | SARS-CoV-2_virus | VOC_B.1.1.529_Omicron | Edil3EGF-like repeats and discoidin I-like domains 3protein coding gene |
MGI | Alliance | Tang AT, bioRxiv 2021 Dec;(): Tang AT, PLoS Biol 2023 Feb;21(2):e3001989 |
Egfr | epidermal growth factor receptor | protein coding gene | MGI:95294 | Venkataraman T, J Virol 2017 Jun 15;91(12): | J:243599 | Pathology | SARS-CoV-MA_virus | Egfrepidermal growth factor receptorprotein coding gene |
MGI | Alliance | Venkataraman T, J Virol 2017 Jun 15;91(12): |
Egr1 | early growth response 1 | protein coding gene | MGI:95295 | Li SW, Sci Rep 2016 May 13;6():25754 | J:291621 | SARS-CoV_virus | Egr1early growth response 1protein coding gene |
MGI | Alliance | Li SW, Sci Rep 2016 May 13;6():25754 |
Eif2ak2 | eukaryotic translation initiation factor 2-alpha kinase 2 | protein coding gene | MGI:1353449 | Kapil P, J Neuroimmunol 2014 May 15;270(1-2):1-12 Kindler E, PLoS Pathog 2017 Feb;13(2):e1006195 | J:318208 J:291588 | Mouse_Hepatitis_virus HCoV-229E_virus | Mouse_Hepatitis_virus | Eif2ak2eukaryotic translation initiation factor 2-alpha kinase 2protein coding gene |
MGI | Alliance | Kapil P, J Neuroimmunol 2014 May 15;270(1-2):1-12 Kindler E, PLoS Pathog 2017 Feb;13(2):e1006195 |
Elane | elastase, neutrophil expressed | protein coding gene | MGI:2679229 | Kim E, Proc Natl Acad Sci U S A 2021 Aug 24;118(34):e2102435118 | J:313327 | SARS-CoV-2_virus | Vaccine | Elaneelastase, neutrophil expressedprotein coding gene |
MGI | Alliance | Kim E, Proc Natl Acad Sci U S A 2021 Aug 24;118(34):e2102435118 |
Epor | erythropoietin receptor | protein coding gene | MGI:95408 | Lam LKM, Sci Transl Med 2021 Oct 20;13(616):eabj1008 | J:325468 | SARS-CoV-2_virus | Eporerythropoietin receptorprotein coding gene |
MGI | Alliance | Lam LKM, Sci Transl Med 2021 Oct 20;13(616):eabj1008 |
Fadd | Fas associated via death domain | protein coding gene | MGI:109324 | Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 Wenzel J, Nat Neurosci 2021 Nov;24(11):1522-1533 | J:296686 J:323957 | Pathology | SARS-CoV-2_virus | Treatment Pathology | SARS-CoV-2_virus | VOC_B.1.351_Beta | FaddFas associated via death domainprotein coding gene |
MGI | Alliance | Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 Wenzel J, Nat Neurosci 2021 Nov;24(11):1522-1533 |
Fcer1g | Fc receptor, IgE, high affinity I, gamma polypeptide | protein coding gene | MGI:95496 | Adams LE, Cell Rep 2023 Mar 30;42(4):112326 | J:349062 | SARS-CoV-2-MA_virus | Vaccine | Fcer1gFc receptor, IgE, high affinity I, gamma polypeptideprotein coding gene |
MGI | Alliance | Adams LE, Cell Rep 2023 Mar 30;42(4):112326 |
Fcgrt | Fc fragment of IgG receptor and transporter | protein coding gene | MGI:103017 | Halwe S, bioRxiv 2021 Jun;(): | J:308648 | SARS-CoV-2_virus | Treatment | VOC_B.1.1.7_Alpha | VOC_B.1.351_Beta | FcgrtFc fragment of IgG receptor and transporterprotein coding gene |
MGI | Alliance | Halwe S, bioRxiv 2021 Jun;(): |
Fga | fibrinogen alpha chain | protein coding gene | MGI:1316726 | Ryu JK, bioRxiv 2021;(): | J:311923 | SARS-CoV-2_virus | Treatment | Fgafibrinogen alpha chainprotein coding gene |
MGI | Alliance | Ryu JK, bioRxiv 2021;(): |
Fgg | fibrinogen gamma chain | protein coding gene | MGI:95526 | Ryu JK, bioRxiv 2021;(): | J:311923 | SARS-CoV-2_virus | Treatment | Fggfibrinogen gamma chainprotein coding gene |
MGI | Alliance | Ryu JK, bioRxiv 2021;(): |
Fgl2 | fibrinogen-like protein 2 | protein coding gene | MGI:103266 | Marsden PA, J Clin Invest 2003 Jul;112(1):58-66 | J:99453 | Mouse_Hepatitis_virus | Fgl2fibrinogen-like protein 2protein coding gene |
MGI | Alliance | Marsden PA, J Clin Invest 2003 Jul;112(1):58-66 |
Foxg1 | forkhead box G1 | protein coding gene | MGI:1347464 | Tang AT, bioRxiv 2021 Dec;(): Tang AT, PLoS Biol 2023 Feb;21(2):e3001989 | J:315719 J:337814 | Pathology | SARS-CoV-2_virus Pathology | SARS-CoV-2_virus | VOC_B.1.1.529_Omicron | Foxg1forkhead box G1protein coding gene |
MGI | Alliance | Tang AT, bioRxiv 2021 Dec;(): Tang AT, PLoS Biol 2023 Feb;21(2):e3001989 |
Foxp3 | forkhead box P3 | protein coding gene | MGI:1891436 | Harb H, Immunity 2021 Apr 22;(): Sariol A, J Immunol 2022 Apr 15;208(8):1989-1997 Uraki R, PLoS Pathog 2021 Dec;17(12):e1010085 Zhao J, J Exp Med 2011 Aug 1;208(8):1571-7 Zhao J, PLoS Pathog 2014 Aug;10(8):e1004279 | J:347529 J:324704 J:327784 J:177608 J:247329 | Infection Infection | Mouse_Hepatitis_virus SARS-CoV-2_virus Mouse_Hepatitis_virus | Foxp3forkhead box P3protein coding gene |
MGI | Alliance | Harb H, Immunity 2021 Apr 22;(): Sariol A, J Immunol 2022 Apr 15;208(8):1989-1997 Uraki R, PLoS Pathog 2021 Dec;17(12):e1010085 Zhao J, J Exp Med 2011 Aug 1;208(8):1571-7 Zhao J, PLoS Pathog 2014 Aug;10(8):e1004279 |
G3bp1 | G3BP stress granule assembly factor 1 | protein coding gene | MGI:1351465 | Liu H, J Virol 2022 Jun 22;96(12):e0041222 | J:342298 | Gene | SARS-CoV-2-MA_virus | SARS-CoV-2_virus | G3bp1G3BP stress granule assembly factor 1protein coding gene |
MGI | Alliance | Liu H, J Virol 2022 Jun 22;96(12):e0041222 |
Gbp2 | guanylate binding protein 2 | protein coding gene | MGI:102772 | Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 | J:296686 | Pathology | SARS-CoV-2_virus | Treatment | Gbp2guanylate binding protein 2protein coding gene |
MGI | Alliance | Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 |
Golm1 | golgi membrane protein 1 | protein coding gene | MGI:1917329 | Wan L, Nat Metab 2022 Jan;4(1):29-43 | J:335014 | Pathology | SARS-CoV-2-MA_virus | Golm1golgi membrane protein 1protein coding gene |
MGI | Alliance | Wan L, Nat Metab 2022 Jan;4(1):29-43 |
Gpi1 | glucose-6-phosphate isomerase 1 | protein coding gene | MGI:95797 | Kyuwa S, Microb Pathog 1992 Feb;12(2):95-104 | J:1357 | Mouse_Hepatitis_virus | Gpi1glucose-6-phosphate isomerase 1protein coding gene |
MGI | Alliance | Kyuwa S, Microb Pathog 1992 Feb;12(2):95-104 |
Gpr183 | G protein-coupled receptor 183 | protein coding gene | MGI:2442034 | Fessler MB, Am J Respir Cell Mol Biol 2023 Dec;69(6):638-648 | J:343658 | SARS-CoV-2_virus | Gpr183G protein-coupled receptor 183protein coding gene |
MGI | Alliance | Fessler MB, Am J Respir Cell Mol Biol 2023 Dec;69(6):638-648 |
Gsdmd | gasdermin D | protein coding gene | MGI:1916396 | Eltobgy M, bioRxiv 2021;(): Eltobgy MM, Proc Natl Acad Sci U S A 2022 May 24;119(21):e2202012119 Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 Wu J, Immunity 2021 Nov 9;54(11):2632-2649.e6 Zheng M, J Biol Chem 2020 Oct 9;295(41):14040-14052 | J:311911 J:331823 J:296686 J:323769 J:298138 | Gene | SARS-CoV-2-MA_virus Gene | SARS-CoV-2-MA_virus | SARS-CoV-2_virus Pathology | SARS-CoV-2_virus | Treatment Gene | Pathology Mouse_Hepatitis_virus | Gsdmdgasdermin Dprotein coding gene |
MGI | Alliance | Eltobgy M, bioRxiv 2021;(): Eltobgy MM, Proc Natl Acad Sci U S A 2022 May 24;119(21):e2202012119 Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 Wu J, Immunity 2021 Nov 9;54(11):2632-2649.e6 Zheng M, J Biol Chem 2020 Oct 9;295(41):14040-14052 |
Gsdme | gasdermin E | protein coding gene | MGI:1889850 | Zheng M, J Biol Chem 2020 Oct 9;295(41):14040-14052 | J:298138 | Mouse_Hepatitis_virus | Gsdmegasdermin Eprotein coding gene |
MGI | Alliance | Zheng M, J Biol Chem 2020 Oct 9;295(41):14040-14052 |
H2-Ab1 | histocompatibility 2, class II antigen A, beta 1 | protein coding gene | MGI:103070 | Brentville VA, bioRxiv 2021 Jun;(): Houtman JJ, J Neurovirol 1996 APR;2(2):101-110 | J:308658 J:33974 | SARS-CoV-2_virus | Vaccine Mouse_Hepatitis_virus | H2-Ab1histocompatibility 2, class II antigen A, beta 1protein coding gene |
MGI | Alliance | Brentville VA, bioRxiv 2021 Jun;(): Houtman JJ, J Neurovirol 1996 APR;2(2):101-110 |
Havcr1 | hepatitis A virus cellular receptor 1 | protein coding gene | MGI:2159680 | Yang C, bioRxiv 2020;(): | J:296070 | Infection | SARS-CoV-2_virus | Havcr1hepatitis A virus cellular receptor 1protein coding gene |
MGI | Alliance | Yang C, bioRxiv 2020;(): |
Hey2 | hairy/enhancer-of-split related with YRPW motif 2 | protein coding gene | MGI:1341884 | Hassan AO, Cell Rep 2021 Jul 27;36(4):109452 | J:309629 | SARS-CoV-2_virus | Vaccine | Hey2hairy/enhancer-of-split related with YRPW motif 2protein coding gene |
MGI | Alliance | Hassan AO, Cell Rep 2021 Jul 27;36(4):109452 |
Hopx | HOP homeobox | protein coding gene | MGI:1916782 | Tang AT, PLoS Biol 2023 Feb;21(2):e3001989 | J:337814 | Pathology | SARS-CoV-2_virus | VOC_B.1.1.529_Omicron | HopxHOP homeoboxprotein coding gene |
MGI | Alliance | Tang AT, PLoS Biol 2023 Feb;21(2):e3001989 |
Hspb1 | heat shock protein 1 | protein coding gene | MGI:96240 | Bilinska K, ACS Chem Neurosci 2020 Jun 3;11(11):1555-1562 | J:288137 | Infection | SARS-CoV-2_virus | Hspb1heat shock protein 1protein coding gene |
MGI | Alliance | Bilinska K, ACS Chem Neurosci 2020 Jun 3;11(11):1555-1562 |
Ido1 | indoleamine 2,3-dioxygenase 1 | protein coding gene | MGI:96416 | Grunewald ME, J Virol 2020 Jan 17;94(3): McDermott JE, BMC Syst Biol 2016 Sep 23;10(1):93 | J:290586 J:288523 | Infection | Mouse_Hepatitis_virus Pathology | SARS-CoV-MA_virus | Ido1indoleamine 2,3-dioxygenase 1protein coding gene |
MGI | Alliance | Grunewald ME, J Virol 2020 Jan 17;94(3): McDermott JE, BMC Syst Biol 2016 Sep 23;10(1):93 |
Ifih1 | interferon induced with helicase C domain 1 | protein coding gene | MGI:1918836 | Birdwell LD, J Virol 2016 Jan 6;90(6):3160-72 Deng X, Proc Natl Acad Sci U S A 2017 May 23;114(21):E4251-E4260 Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 Kindler E, PLoS Pathog 2017 Feb;13(2):e1006195 Menachery VD, J Virol 2014 Apr;88(8):4251-64 Zalinger ZB, J Virol 2015 Dec 15;89(24):12330-40 Zheng M, Nat Immunol 2021 Jul;22(7):829-838 Zust R, Nat Immunol 2011 Feb;12(2):137-43 | J:318622 J:242293 J:296686 J:291588 J:213001 J:227926 J:308903 J:168254 | Mouse_Hepatitis_virus Infection | Mouse_Hepatitis_virus Pathology | SARS-CoV-2_virus | Treatment HCoV-229E_virus | Mouse_Hepatitis_virus SARS-CoV-MA_virus | SARS-CoV_virus | Treatment | Vaccine Pathology | SARS-CoV-2_virus | Ifih1interferon induced with helicase C domain 1protein coding gene |
MGI | Alliance | Birdwell LD, J Virol 2016 Jan 6;90(6):3160-72 Deng X, Proc Natl Acad Sci U S A 2017 May 23;114(21):E4251-E4260 Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 Kindler E, PLoS Pathog 2017 Feb;13(2):e1006195 Menachery VD, J Virol 2014 Apr;88(8):4251-64 Zalinger ZB, J Virol 2015 Dec 15;89(24):12330-40 Zheng M, Nat Immunol 2021 Jul;22(7):829-838 Zust R, Nat Immunol 2011 Feb;12(2):137-43 |
Ifit1 | interferon-induced protein with tetratricopeptide repeats 1 | protein coding gene | MGI:99450 | Butchi NB, J Virol 2014 Jan;88(2):1051-64 Daffis S, Nature 2010 Nov 18;468(7322):452-6 Mears HV, J Biol Chem 2020 Dec 18;295(51):17781-17801 Menachery VD, J Virol 2014 Apr;88(8):4251-64 | J:205203 J:187561 J:302651 J:213001 | Mouse_Hepatitis_virus SARS-CoV-MA_virus | SARS-CoV_virus | Treatment | Vaccine | Ifit1interferon-induced protein with tetratricopeptide repeats 1protein coding gene |
MGI | Alliance | Butchi NB, J Virol 2014 Jan;88(2):1051-64 Daffis S, Nature 2010 Nov 18;468(7322):452-6 Mears HV, J Biol Chem 2020 Dec 18;295(51):17781-17801 Menachery VD, J Virol 2014 Apr;88(8):4251-64 |
Ifit1bl1 | interferon induced protein with tetratricpeptide repeats 1B like 1 | protein coding gene | MGI:3650685 | Mears HV, J Biol Chem 2020 Dec 18;295(51):17781-17801 | J:302651 | Mouse_Hepatitis_virus | Ifit1bl1interferon induced protein with tetratricpeptide repeats 1B like 1protein coding gene |
MGI | Alliance | Mears HV, J Biol Chem 2020 Dec 18;295(51):17781-17801 |
Ifit1bl2 | interferon induced protein with tetratricopeptide repeats 1B like 2 | protein coding gene | MGI:2148249 | Mears HV, J Biol Chem 2020 Dec 18;295(51):17781-17801 | J:302651 | Mouse_Hepatitis_virus | Ifit1bl2interferon induced protein with tetratricopeptide repeats 1B like 2protein coding gene |
MGI | Alliance | Mears HV, J Biol Chem 2020 Dec 18;295(51):17781-17801 |
Ifit2 | interferon-induced protein with tetratricopeptide repeats 2 | protein coding gene | MGI:99449 | Butchi NB, J Virol 2014 Jan;88(2):1051-64 Daffis S, Nature 2010 Nov 18;468(7322):452-6 Das Sarma J, PLoS Pathog 2020 Nov;16(11):e1009034 | J:205203 J:187561 J:313166 | Mouse_Hepatitis_virus | Ifit2interferon-induced protein with tetratricopeptide repeats 2protein coding gene |
MGI | Alliance | Butchi NB, J Virol 2014 Jan;88(2):1051-64 Daffis S, Nature 2010 Nov 18;468(7322):452-6 Das Sarma J, PLoS Pathog 2020 Nov;16(11):e1009034 |
Ifitm1 | interferon induced transmembrane protein 1 | protein coding gene | MGI:1915963 | Huang IC, PLoS Pathog 2011;7(1):e1001258 | J:187558 | SARS-CoV_virus | Ifitm1interferon induced transmembrane protein 1protein coding gene |
MGI | Alliance | Huang IC, PLoS Pathog 2011;7(1):e1001258 |
Ifitm2 | interferon induced transmembrane protein 2 | protein coding gene | MGI:1933382 | Huang IC, PLoS Pathog 2011;7(1):e1001258 | J:187558 | SARS-CoV_virus | Ifitm2interferon induced transmembrane protein 2protein coding gene |
MGI | Alliance | Huang IC, PLoS Pathog 2011;7(1):e1001258 |
Ifitm3 | interferon induced transmembrane protein 3 | protein coding gene | MGI:1913391 | Huang IC, PLoS Pathog 2011;7(1):e1001258 Zani A, bioRxiv 2021Dec;(): | J:187558 J:316764 | SARS-CoV_virus Gene | SARS-CoV-2-MA_virus | SARS-CoV-2_virus | Ifitm3interferon induced transmembrane protein 3protein coding gene |
MGI | Alliance | Huang IC, PLoS Pathog 2011;7(1):e1001258 Zani A, bioRxiv 2021Dec;(): |
Ifnar1 | interferon (alpha and beta) receptor 1 | protein coding gene | MGI:107658 | Ahan RE, bioRxiv 2021 Jul;(): Anand G, bioRxiv 2020 Dec;(): Birdwell LD, J Virol 2016 Jan 6;90(6):3160-72 Cervantes-Barragan L, Blood 2007 Feb 1;109(3):1131-7 Cervantes-Barragan L, J Immunol 2009 Jan 15;182(2):1099-106 Channappanavar R, Cell Host Microbe 2016 Feb 10;19(2):181-93 Daffis S, Nature 2010 Nov 18;468(7322):452-6 Dangi T, bioRxiv 2021 Jun;(): Deng X, J Virol 2014 Oct 15;88(20):11886-98 Deng X, Proc Natl Acad Sci U S A 2017 May 23;114(21):E4251-E4260 Fehr AR, J Virol 2015 Feb;89(3):1523-36 Frieman MB, PLoS Pathog 2010 Apr 8;6(4):e1000849 Grunewald ME, J Virol 2020 Jan 17;94(3): Guo Q, Cell Host Microbe 2021 Feb 10;29(2):222-235.e4 Hassan AO, Cell 2020 Jun 10;(): Hassert M, PLoS Pathog 2020 Dec;16(12):e1009163 Hilligan KL, Nat Commun 2023 Dec 12;14(1):8229 Horner C, Proc Natl Acad Sci U S A 2020 Dec 22;117(51):32657-32666 Ireland DD, J Virol 2008 Jan;82(1):300-10 Israelow B, J Exp Med 2020 Dec 7;217(12): Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 Lu M, Proc Natl Acad Sci U S A 2021 Mar 23;118(12):e2026153118 Madar-Balakirski N, bioRxiv 2021 Jul;(): Malczyk AH, J Virol 2015 Nov;89(22):11654-67 Mao T, bioRxiv 2021 Jun;(): Menachery VD, J Virol 2014 Apr;88(8):4251-64 Miner JJ, Cell Rep 2020 Nov 3;33(5):108339 Ngo VL, Cell Host Microbe 2024 Jan 23;(): Ogger PP, Eur J Immunol 2022 Nov;52(11):1768-1775 Peng X, mBio 2010 Oct 26;1(5): Phares TW, J Immunol 2009 May 1;182(9):5430-8 Rawle DJ, bioRxiv 2021 Feb;(): Sun J, Cell 2020 Jun 10;(): Tada T, Proc Natl Acad Sci U S A 2023 Jun 6;120(23):e2303509120 Xiao Y, Cell 2021 Dec 9;184(25):6037-6051.e14 Yang J, Nature 2020 Jul 29;(): Zhao J, Proc Natl Acad Sci U S A 2014 Apr 1;111(13):4970-5 | J:308572 J:298270 J:318622 J:144400 J:143484 J:291874 J:187561 J:308670 J:214600 J:242293 J:221981 J:286237 J:290586 J:308901 J:290258 J:319459 J:343550 J:300105 J:145215 J:291862 J:296686 J:303467 J:308635 J:312515 J:308656 J:213001 J:300094 J:345954 J:333792 J:276986 J:147948 J:302157 J:291881 J:338414 J:317125 J:292665 J:207380 | SARS-CoV-2_virus | Treatment Pathology | SARS-CoV-2_virus Mouse_Hepatitis_virus Infection | Mouse_Hepatitis_virus | SARS-CoV_virus Gene | Infection | Pathology | SARS-CoV-MA_virus SARS-CoV-2_virus | SARS-CoV_virus | Vaccine Mouse_Hepatitis_virus | Pathology Infection | Mouse_Hepatitis_virus Pathology | SARS-CoV-MA_virus Infection | SARS-CoV-2_virus | Treatment Infection | SARS-CoV-2_virus SARS-CoV-2_virus | Vaccine Infection | Pathology | SARS-CoV-2_virus Pathology | SARS-CoV-2_virus | Treatment MERS-CoV_virus | Vaccine Treatment | VOC_B.1.1.7_Alpha | VOC_B.1.351_Beta | VOC_P.1_Gamma SARS-CoV-MA_virus | SARS-CoV_virus | Treatment | Vaccine SARS-CoV-2_virus Infection | MERS-CoV-MA_virus Infection | SARS-CoV-MA_virus Infection | Pathology | SARS-CoV-2_virus | Treatment SARS-CoV-2_virus | Treatment | VOC_B.1.1.529_Omicron SARS-CoV-2_virus | Treatment | VOC_B.1.1.7_Alpha | VOC_B.1.427 | VOC_B.1.617.2_Delta MERS-CoV_virus | Ifnar1interferon (alpha and beta) receptor 1protein coding gene |
MGI | Alliance | Ahan RE, bioRxiv 2021 Jul;(): Anand G, bioRxiv 2020 Dec;(): Birdwell LD, J Virol 2016 Jan 6;90(6):3160-72 Cervantes-Barragan L, Blood 2007 Feb 1;109(3):1131-7 Cervantes-Barragan L, J Immunol 2009 Jan 15;182(2):1099-106 Channappanavar R, Cell Host Microbe 2016 Feb 10;19(2):181-93 Daffis S, Nature 2010 Nov 18;468(7322):452-6 Dangi T, bioRxiv 2021 Jun;(): Deng X, J Virol 2014 Oct 15;88(20):11886-98 Deng X, Proc Natl Acad Sci U S A 2017 May 23;114(21):E4251-E4260 Fehr AR, J Virol 2015 Feb;89(3):1523-36 Frieman MB, PLoS Pathog 2010 Apr 8;6(4):e1000849 Grunewald ME, J Virol 2020 Jan 17;94(3): Guo Q, Cell Host Microbe 2021 Feb 10;29(2):222-235.e4 Hassan AO, Cell 2020 Jun 10;(): Hassert M, PLoS Pathog 2020 Dec;16(12):e1009163 Hilligan KL, Nat Commun 2023 Dec 12;14(1):8229 Horner C, Proc Natl Acad Sci U S A 2020 Dec 22;117(51):32657-32666 Ireland DD, J Virol 2008 Jan;82(1):300-10 Israelow B, J Exp Med 2020 Dec 7;217(12): Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 Lu M, Proc Natl Acad Sci U S A 2021 Mar 23;118(12):e2026153118 Madar-Balakirski N, bioRxiv 2021 Jul;(): Malczyk AH, J Virol 2015 Nov;89(22):11654-67 Mao T, bioRxiv 2021 Jun;(): Menachery VD, J Virol 2014 Apr;88(8):4251-64 Miner JJ, Cell Rep 2020 Nov 3;33(5):108339 Ngo VL, Cell Host Microbe 2024 Jan 23;(): Ogger PP, Eur J Immunol 2022 Nov;52(11):1768-1775 Peng X, mBio 2010 Oct 26;1(5): Phares TW, J Immunol 2009 May 1;182(9):5430-8 Rawle DJ, bioRxiv 2021 Feb;(): Sun J, Cell 2020 Jun 10;(): Tada T, Proc Natl Acad Sci U S A 2023 Jun 6;120(23):e2303509120 Xiao Y, Cell 2021 Dec 9;184(25):6037-6051.e14 Yang J, Nature 2020 Jul 29;(): Zhao J, Proc Natl Acad Sci U S A 2014 Apr 1;111(13):4970-5 |
Ifnar2 | interferon (alpha and beta) receptor 2 | protein coding gene | MGI:1098243 | Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 Rawle DJ, bioRxiv 2021 Feb;(): | J:296686 J:302157 | Pathology | SARS-CoV-2_virus | Treatment SARS-CoV-2_virus | Ifnar2interferon (alpha and beta) receptor 2protein coding gene |
MGI | Alliance | Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 Rawle DJ, bioRxiv 2021 Feb;(): |
Ifnb1 | interferon beta 1, fibroblast | protein coding gene | MGI:107657 | Butchi NB, J Virol 2014 Jan;88(2):1051-64 | J:205203 | Mouse_Hepatitis_virus | Ifnb1interferon beta 1, fibroblastprotein coding gene |
MGI | Alliance | Butchi NB, J Virol 2014 Jan;88(2):1051-64 |
Ifng | interferon gamma | protein coding gene | MGI:107656 | Dandekar AA, Am J Pathol 2004 Feb;164(2):363-9 France MP, Aust Vet J 1999 Sep;77(9):600-4 Gonzalez JM, Am J Pathol 2006 Mar;168(3):796-804 Kyuwa S, J Virol 1998 Nov;72(11):9286-90 Kyuwa S, Virus Res 2002 Feb 26;83(1-2):169-77 Malone KE, Glia 2008 Mar;56(4):426-35 Parra B, J Immunol 1999 Feb 1;162(3):1641-7 Phares TW, J Immunol 2009 May 1;182(9):5430-8 Savarin C, J Neuroinflammation 2012 May 29;9():104 Sun J, Cell 2020 Jun 10;(): Templeton SP, J Neuroimmunol 2008 Feb;194(1-2):18-26 | J:88552 J:59661 J:106482 J:50405 J:91691 J:156284 J:112048 J:147948 J:331807 J:291881 J:131907 | Mouse_Hepatitis_virus Mouse_Hepatitis_virus | Pathology Infection | Mouse_Hepatitis_virus Infection | Mouse_Hepatitis_virus | Pathology Infection | Pathology | SARS-CoV-2_virus | Treatment | Ifnginterferon gammaprotein coding gene |
MGI | Alliance | Dandekar AA, Am J Pathol 2004 Feb;164(2):363-9 France MP, Aust Vet J 1999 Sep;77(9):600-4 Gonzalez JM, Am J Pathol 2006 Mar;168(3):796-804 Kyuwa S, J Virol 1998 Nov;72(11):9286-90 Kyuwa S, Virus Res 2002 Feb 26;83(1-2):169-77 Malone KE, Glia 2008 Mar;56(4):426-35 Parra B, J Immunol 1999 Feb 1;162(3):1641-7 Phares TW, J Immunol 2009 May 1;182(9):5430-8 Savarin C, J Neuroinflammation 2012 May 29;9():104 Sun J, Cell 2020 Jun 10;(): Templeton SP, J Neuroimmunol 2008 Feb;194(1-2):18-26 |
Ifngr1 | interferon gamma receptor 1 | protein coding gene | MGI:107655 | Frieman MB, PLoS Pathog 2010 Apr 8;6(4):e1000849 Hassan AO, Cell 2020 Jun 10;(): Hilligan KL, Nat Commun 2023 Dec 12;14(1):8229 Miner JJ, Cell Rep 2020 Nov 3;33(5):108339 Schijns VE, J Immunol 1996 Jul 15;157(2):815-21 Templeton SP, J Neuroimmunol 2008 Feb;194(1-2):18-26 | J:286237 J:290258 J:343550 J:300094 J:34040 J:131907 | Pathology | SARS-CoV-MA_virus Infection | SARS-CoV-2_virus | Treatment SARS-CoV-2_virus Mouse_Hepatitis_virus | Ifngr1interferon gamma receptor 1protein coding gene |
MGI | Alliance | Frieman MB, PLoS Pathog 2010 Apr 8;6(4):e1000849 Hassan AO, Cell 2020 Jun 10;(): Hilligan KL, Nat Commun 2023 Dec 12;14(1):8229 Miner JJ, Cell Rep 2020 Nov 3;33(5):108339 Schijns VE, J Immunol 1996 Jul 15;157(2):815-21 Templeton SP, J Neuroimmunol 2008 Feb;194(1-2):18-26 |
Ifnl2 | interferon lambda 2 | protein coding gene | MGI:3647279 | Chong Z, Cell Rep 2022 May 10;39(6):110799 | J:325089 | SARS-CoV-2_virus | Treatment | VOC_B.1.1.529_Omicron | VOC_B.1.351_Beta | Ifnl2interferon lambda 2protein coding gene |
MGI | Alliance | Chong Z, Cell Rep 2022 May 10;39(6):110799 |
Ifnlr1 | interferon lambda receptor 1 | protein coding gene | MGI:2429859 | Chong Z, bioRxiv 2022;(): Chong Z, Cell Rep 2022 May 10;39(6):110799 Frieman MB, PLoS Pathog 2010 Apr 8;6(4):e1000849 Miner JJ, Cell Rep 2020 Nov 3;33(5):108339 | J:321761 J:325089 J:286237 J:300094 | SARS-CoV-2_virus | Treatment | VOC_B.1.1.529_Omicron | VOC_B.1.351_Beta Pathology | SARS-CoV-MA_virus SARS-CoV-2_virus | Ifnlr1interferon lambda receptor 1protein coding gene |
MGI | Alliance | Chong Z, bioRxiv 2022;(): Chong Z, Cell Rep 2022 May 10;39(6):110799 Frieman MB, PLoS Pathog 2010 Apr 8;6(4):e1000849 Miner JJ, Cell Rep 2020 Nov 3;33(5):108339 |
Ighm | immunoglobulin heavy constant mu | gene segment | MGI:96448 | Bergmann CC, J Immunol 2001 Aug 1;167(3):1575-83 Israelow B, bioRxiv 2021 May;(): Sarden N, Sci Transl Med 2022 Dec 7;14(674):eabq6682 Zhao J, Proc Natl Acad Sci U S A 2014 Apr 1;111(13):4970-5 | J:120484 J:308733 J:336666 J:207380 | Mouse_Hepatitis_virus Infection | SARS-CoV-2_virus Comorbidity | SARS-CoV-2_virus MERS-CoV_virus | Ighmimmunoglobulin heavy constant mugene segment |
MGI | Alliance | Bergmann CC, J Immunol 2001 Aug 1;167(3):1575-83 Israelow B, bioRxiv 2021 May;(): Sarden N, Sci Transl Med 2022 Dec 7;14(674):eabq6682 Zhao J, Proc Natl Acad Sci U S A 2014 Apr 1;111(13):4970-5 |
Ikbkb | inhibitor of kappaB kinase beta | protein coding gene | MGI:1338071 | Satta S, Theranostics 2022;12(6):2639-2657 | J:331825 | SARS-CoV-2_virus | Variant | Ikbkbinhibitor of kappaB kinase betaprotein coding gene |
MGI | Alliance | Satta S, Theranostics 2022;12(6):2639-2657 |
Ikbkg | inhibitor of kappaB kinase gamma | protein coding gene | MGI:1338074 | Wenzel J, Nat Neurosci 2021 Nov;24(11):1522-1533 | J:323957 | Pathology | SARS-CoV-2_virus | VOC_B.1.351_Beta | Ikbkginhibitor of kappaB kinase gammaprotein coding gene |
MGI | Alliance | Wenzel J, Nat Neurosci 2021 Nov;24(11):1522-1533 |
Il10 | interleukin 10 | protein coding gene | MGI:96537 | Kapil P, J Neuroimmunol 2014 May 15;270(1-2):1-12 Puntambekar SS, Glia 2015 Jun 30;(): Trandem K, J Immunol 2011 Mar 15;186(6):3642-52 | J:318208 J:225834 J:169759 | Mouse_Hepatitis_virus Mouse_Hepatitis_virus | Pathology | Il10interleukin 10protein coding gene |
MGI | Alliance | Kapil P, J Neuroimmunol 2014 May 15;270(1-2):1-12 Puntambekar SS, Glia 2015 Jun 30;(): Trandem K, J Immunol 2011 Mar 15;186(6):3642-52 |
Il12b | interleukin 12b | protein coding gene | MGI:96540 | Schijns VE, J Immunol 1996 Jul 15;157(2):815-21 | J:34040 | Mouse_Hepatitis_virus | Il12binterleukin 12bprotein coding gene |
MGI | Alliance | Schijns VE, J Immunol 1996 Jul 15;157(2):815-21 |
Il17a | interleukin 17A | protein coding gene | MGI:107364 | Lin X, iScience 2021 Apr 23;24(4):102293 Savarin C, J Neuroinflammation 2012 May 29;9():104 | J:304178 J:331807 | Pathology | SARS-CoV-2_virus | Treatment Mouse_Hepatitis_virus | Il17ainterleukin 17Aprotein coding gene |
MGI | Alliance | Lin X, iScience 2021 Apr 23;24(4):102293 Savarin C, J Neuroinflammation 2012 May 29;9():104 |
Il17ra | interleukin 17 receptor A | protein coding gene | MGI:107399 | Lin X, iScience 2021 Apr 23;24(4):102293 | J:304178 | Pathology | SARS-CoV-2_virus | Treatment | Il17rainterleukin 17 receptor Aprotein coding gene |
MGI | Alliance | Lin X, iScience 2021 Apr 23;24(4):102293 |
Il18 | interleukin 18 | protein coding gene | MGI:107936 | Zalinger ZB, J Neurovirol 2017 Dec;23(6):845-854 | J:331829 | Mouse_Hepatitis_virus | Il18interleukin 18protein coding gene |
MGI | Alliance | Zalinger ZB, J Neurovirol 2017 Dec;23(6):845-854 |
Il18r1 | interleukin 18 receptor 1 | protein coding gene | MGI:105383 | Sheahan T, PLoS Pathog 2008 Dec;4(12):e1000240 Zalinger ZB, J Neurovirol 2017 Dec;23(6):845-854 | J:162707 J:331829 | Pathology | SARS-CoV-MA_virus Mouse_Hepatitis_virus | Il18r1interleukin 18 receptor 1protein coding gene |
MGI | Alliance | Sheahan T, PLoS Pathog 2008 Dec;4(12):e1000240 Zalinger ZB, J Neurovirol 2017 Dec;23(6):845-854 |
Il1b | interleukin 1 beta | protein coding gene | MGI:96543 | Yang J, Nature 2020 Jul 29;(): | J:292665 | SARS-CoV-2_virus | Vaccine | Il1binterleukin 1 betaprotein coding gene |
MGI | Alliance | Yang J, Nature 2020 Jul 29;(): |
Il1r1 | interleukin 1 receptor, type I | protein coding gene | MGI:96545 | Sheahan T, PLoS Pathog 2008 Dec;4(12):e1000240 Zalinger ZB, J Neurovirol 2017 Dec;23(6):845-854 | J:162707 J:331829 | Pathology | SARS-CoV-MA_virus Mouse_Hepatitis_virus | Il1r1interleukin 1 receptor, type Iprotein coding gene |
MGI | Alliance | Sheahan T, PLoS Pathog 2008 Dec;4(12):e1000240 Zalinger ZB, J Neurovirol 2017 Dec;23(6):845-854 |
Il21 | interleukin 21 | protein coding gene | MGI:1890474 | Phares TW, J Neuroimmunol 2013 Oct 15;263(1-2):43-54 | J:318137 | Mouse_Hepatitis_virus | Il21interleukin 21protein coding gene |
MGI | Alliance | Phares TW, J Neuroimmunol 2013 Oct 15;263(1-2):43-54 |
Il2rg | interleukin 2 receptor, gamma chain | protein coding gene | MGI:96551 | Halwe S, bioRxiv 2021 Jun;(): Hu Z, bioRxiv 2021 Nov;(): Ngo VL, Cell Host Microbe 2024 Jan 23;(): Sefik E, bioRxiv 2021;(): | J:308648 J:313461 J:345954 J:311907 | SARS-CoV-2_virus | Treatment | VOC_B.1.1.7_Alpha | VOC_B.1.351_Beta Infection | SARS-CoV-2_virus Infection | MERS-CoV-MA_virus SARS-CoV-2_virus | Il2rginterleukin 2 receptor, gamma chainprotein coding gene |
MGI | Alliance | Halwe S, bioRxiv 2021 Jun;(): Hu Z, bioRxiv 2021 Nov;(): Ngo VL, Cell Host Microbe 2024 Jan 23;(): Sefik E, bioRxiv 2021;(): |
Il3 | interleukin 3 | protein coding gene | MGI:96552 | Sefik E, bioRxiv 2021;(): | J:311907 | SARS-CoV-2_virus | Il3interleukin 3protein coding gene |
MGI | Alliance | Sefik E, bioRxiv 2021;(): |
Il6 | interleukin 6 | protein coding gene | MGI:96559 | Alameh MG, Immunity 2021 Dec 14;54(12):2877-2892.e7 Imai Y, Cell 2008 Apr 18;133(2):235-49 Kumaki Y, Antiviral Res 2017 Mar;139():1-12 Ndeupen S, bioRxiv 2021 Aug;(): Sefik E, bioRxiv 2021;(): | J:337329 J:145306 J:286953 J:308580 J:311907 | SARS-CoV-2_virus | Vaccine SARS-CoV_virus SARS-CoV-MA_virus | SARS-CoV_virus | Treatment SARS-CoV-2_virus | Il6interleukin 6protein coding gene |
MGI | Alliance | Alameh MG, Immunity 2021 Dec 14;54(12):2877-2892.e7 Imai Y, Cell 2008 Apr 18;133(2):235-49 Kumaki Y, Antiviral Res 2017 Mar;139():1-12 Ndeupen S, bioRxiv 2021 Aug;(): Sefik E, bioRxiv 2021;(): |
Il6ra | interleukin 6 receptor, alpha | protein coding gene | MGI:105304 | Harb H, Immunity 2021 Apr 22;(): | J:347529 | Infection | Il6rainterleukin 6 receptor, alphaprotein coding gene |
MGI | Alliance | Harb H, Immunity 2021 Apr 22;(): |
Irf1 | interferon regulatory factor 1 | protein coding gene | MGI:96590 | Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 | J:296686 | Pathology | SARS-CoV-2_virus | Treatment | Irf1interferon regulatory factor 1protein coding gene |
MGI | Alliance | Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 |
Irf3 | interferon regulatory factor 3 | protein coding gene | MGI:1859179 | Daffis S, Nature 2010 Nov 18;468(7322):452-6 Guo Q, Cell Host Microbe 2021 Feb 10;29(2):222-235.e4 Imai Y, Cell 2008 Apr 18;133(2):235-49 Israelow B, J Exp Med 2020 Dec 7;217(12): Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 Kindler E, PLoS Pathog 2017 Feb;13(2):e1006195 | J:187561 J:308901 J:145306 J:291862 J:296686 J:291588 | Mouse_Hepatitis_virus Pathology | SARS-CoV-2_virus SARS-CoV_virus Infection | Pathology | SARS-CoV-2_virus Pathology | SARS-CoV-2_virus | Treatment HCoV-229E_virus | Mouse_Hepatitis_virus | Irf3interferon regulatory factor 3protein coding gene |
MGI | Alliance | Daffis S, Nature 2010 Nov 18;468(7322):452-6 Guo Q, Cell Host Microbe 2021 Feb 10;29(2):222-235.e4 Imai Y, Cell 2008 Apr 18;133(2):235-49 Israelow B, J Exp Med 2020 Dec 7;217(12): Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 Kindler E, PLoS Pathog 2017 Feb;13(2):e1006195 |
Irf5 | interferon regulatory factor 5 | protein coding gene | MGI:1350924 | Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 Kindler E, PLoS Pathog 2017 Feb;13(2):e1006195 | J:296686 J:291588 | Pathology | SARS-CoV-2_virus | Treatment HCoV-229E_virus | Mouse_Hepatitis_virus | Irf5interferon regulatory factor 5protein coding gene |
MGI | Alliance | Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 Kindler E, PLoS Pathog 2017 Feb;13(2):e1006195 |
Irf7 | interferon regulatory factor 7 | protein coding gene | MGI:1859212 | Daffis S, Nature 2010 Nov 18;468(7322):452-6 Guo Q, Cell Host Microbe 2021 Feb 10;29(2):222-235.e4 Israelow B, J Exp Med 2020 Dec 7;217(12): Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 Kindler E, PLoS Pathog 2017 Feb;13(2):e1006195 | J:187561 J:308901 J:291862 J:296686 J:291588 | Mouse_Hepatitis_virus Pathology | SARS-CoV-2_virus Infection | Pathology | SARS-CoV-2_virus Pathology | SARS-CoV-2_virus | Treatment HCoV-229E_virus | Mouse_Hepatitis_virus | Irf7interferon regulatory factor 7protein coding gene |
MGI | Alliance | Daffis S, Nature 2010 Nov 18;468(7322):452-6 Guo Q, Cell Host Microbe 2021 Feb 10;29(2):222-235.e4 Israelow B, J Exp Med 2020 Dec 7;217(12): Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 Kindler E, PLoS Pathog 2017 Feb;13(2):e1006195 |
Irf9 | interferon regulatory factor 9 | protein coding gene | MGI:107587 | Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 | J:296686 | Pathology | SARS-CoV-2_virus | Treatment | Irf9interferon regulatory factor 9protein coding gene |
MGI | Alliance | Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 |
Isg15 | ISG15 ubiquitin-like modifier | protein coding gene | MGI:1855694 | Daczkowski CM, J Mol Biol 2017 Jun 2;429(11):1661-1683 Ma XZ, J Virol 2014 Jun;88(11):6195-204 | J:296108 J:214425 | Gene | MERS-CoV_virus | Mouse_Hepatitis_virus | SARS-CoV_virus Mouse_Hepatitis_virus | Isg15ISG15 ubiquitin-like modifierprotein coding gene |
MGI | Alliance | Daczkowski CM, J Mol Biol 2017 Jun 2;429(11):1661-1683 Ma XZ, J Virol 2014 Jun;88(11):6195-204 |
Itgal | integrin alpha L | protein coding gene | MGI:96606 | Kyuwa S, Microb Pathog 1992 Feb;12(2):95-104 | J:1357 | Mouse_Hepatitis_virus | Itgalintegrin alpha Lprotein coding gene |
MGI | Alliance | Kyuwa S, Microb Pathog 1992 Feb;12(2):95-104 |
Kctd9 | potassium channel tetramerisation domain containing 9 | protein coding gene | MGI:2145579 | Zhang X, Front Immunol 2019;10():744 | J:281803 | Mouse_Hepatitis_virus | Kctd9potassium channel tetramerisation domain containing 9protein coding gene |
MGI | Alliance | Zhang X, Front Immunol 2019;10():744 |
Ldlr | low density lipoprotein receptor | protein coding gene | MGI:96765 | Ensor CM, bioRxiv 2021-09;(): | J:310122 | SARS-CoV-2_virus | Ldlrlow density lipoprotein receptorprotein coding gene |
MGI | Alliance | Ensor CM, bioRxiv 2021-09;(): |
Lepr | leptin receptor | protein coding gene | MGI:104993 | Choi JY, Biochem Biophys Res Commun 2020 Jul 30;528(3):413-419 Vergara A, Mol Cell Endocrinol 2021 Jun 1;529():111263 | J:292007 J:308897 | Gene Comorbidity | Leprleptin receptorprotein coding gene |
MGI | Alliance | Choi JY, Biochem Biophys Res Commun 2020 Jul 30;528(3):413-419 Vergara A, Mol Cell Endocrinol 2021 Jun 1;529():111263 |
Ltb4r1 | leukotriene B4 receptor 1 | protein coding gene | MGI:1309472 | Sarden N, Sci Transl Med 2022 Dec 7;14(674):eabq6682 | J:336666 | Comorbidity | SARS-CoV-2_virus | Ltb4r1leukotriene B4 receptor 1protein coding gene |
MGI | Alliance | Sarden N, Sci Transl Med 2022 Dec 7;14(674):eabq6682 |
Ly6e | lymphocyte antigen 6 family member E | protein coding gene | MGI:106651 | Pfaender S, Nat Microbiol 2020 Jul 23;(): | J:291868 | Gene | HCoV-229E_virus | HCoV-OC43_virus | MERS-CoV_virus | Mouse_Hepatitis_virus | SARS-CoV-2_virus | SARS-CoV_virus | Ly6elymphocyte antigen 6 family member Eprotein coding gene |
MGI | Alliance | Pfaender S, Nat Microbiol 2020 Jul 23;(): |
Lyst | lysosomal trafficking regulator | protein coding gene | MGI:107448 | Glass WG, J Immunol 2004 Sep 15;173(6):4030-9 | J:92752 | Infection | SARS-CoV_virus | Lystlysosomal trafficking regulatorprotein coding gene |
MGI | Alliance | Glass WG, J Immunol 2004 Sep 15;173(6):4030-9 |
Lyz2 | lysozyme 2 | protein coding gene | MGI:96897 | Cervantes-Barragan L, J Immunol 2009 Jan 15;182(2):1099-106 de Almeida L, Sci Adv 2022 Sep 16;8(37):eabo5400 Imai Y, Cell 2008 Apr 18;133(2):235-49 Melvin WJ, Proc Natl Acad Sci U S A 2021 Sep 21;118(38):e2101071118 Musiu C, Cell Death Differ 2021 Sep 13;(): Page C, J Virol 2012 Dec;86(24):13334-49 Satta S, Theranostics 2022;12(6):2639-2657 Verma AK, mBio 2021 Oct 26;12(5):e0196921 Wang Y, Sci Adv 2021 Jan;7(1): Zhao Z, Autophagy 2007 Nov-Dec;3(6):581-5 | J:143484 J:331763 J:145306 J:311033 J:313338 J:286337 J:331825 J:313438 J:314537 J:282479 | Mouse_Hepatitis_virus SARS-CoV-2_virus SARS-CoV_virus Comorbidity | Gene | Mouse_Hepatitis_virus Pathology | SARS-CoV-2_virus Pathology | SARS-CoV_virus SARS-CoV-2_virus | Variant | Lyz2lysozyme 2protein coding gene |
MGI | Alliance | Cervantes-Barragan L, J Immunol 2009 Jan 15;182(2):1099-106 de Almeida L, Sci Adv 2022 Sep 16;8(37):eabo5400 Imai Y, Cell 2008 Apr 18;133(2):235-49 Melvin WJ, Proc Natl Acad Sci U S A 2021 Sep 21;118(38):e2101071118 Musiu C, Cell Death Differ 2021 Sep 13;(): Page C, J Virol 2012 Dec;86(24):13334-49 Satta S, Theranostics 2022;12(6):2639-2657 Verma AK, mBio 2021 Oct 26;12(5):e0196921 Wang Y, Sci Adv 2021 Jan;7(1): Zhao Z, Autophagy 2007 Nov-Dec;3(6):581-5 |
Mavs | mitochondrial antiviral signaling protein | protein coding gene | MGI:2444773 | Alameh MG, Immunity 2021 Dec 14;54(12):2877-2892.e7 Channappanavar R, J Clin Invest 2019 Jul 29;130():3625-3639 Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 Kindler E, PLoS Pathog 2017 Feb;13(2):e1006195 Zhao J, Proc Natl Acad Sci U S A 2014 Apr 1;111(13):4970-5 Zheng M, Nat Immunol 2021 Jul;22(7):829-838 | J:337329 J:288107 J:296686 J:291588 J:207380 J:308903 | SARS-CoV-2_virus | Vaccine Infection | MERS-CoV-MA_virus | Treatment Pathology | SARS-CoV-2_virus | Treatment HCoV-229E_virus | Mouse_Hepatitis_virus MERS-CoV_virus Pathology | SARS-CoV-2_virus | Mavsmitochondrial antiviral signaling proteinprotein coding gene |
MGI | Alliance | Alameh MG, Immunity 2021 Dec 14;54(12):2877-2892.e7 Channappanavar R, J Clin Invest 2019 Jul 29;130():3625-3639 Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 Kindler E, PLoS Pathog 2017 Feb;13(2):e1006195 Zhao J, Proc Natl Acad Sci U S A 2014 Apr 1;111(13):4970-5 Zheng M, Nat Immunol 2021 Jul;22(7):829-838 |
Mbd2 | methyl-CpG binding domain protein 2 | protein coding gene | MGI:1333813 | Wang Y, Sci Adv 2021 Jan;7(1): | J:314537 | SARS-CoV-2_virus | Mbd2methyl-CpG binding domain protein 2protein coding gene |
MGI | Alliance | Wang Y, Sci Adv 2021 Jan;7(1): |
Mcph1 | microcephaly, primary autosomal recessive 1 | protein coding gene | MGI:2443308 | Carter B, bioRxiv 2021 May;(): | J:308712 | SARS-CoV-2_virus | Vaccine | Mcph1microcephaly, primary autosomal recessive 1protein coding gene |
MGI | Alliance | Carter B, bioRxiv 2021 May;(): |
Mir155 | microRNA 155 | miRNA gene | MGI:2676840 | Soni DK, bioRxiv 2020 Dec;(): | J:299096 | SARS-CoV-2_virus | Treatment | Mir155microRNA 155miRNA gene |
MGI | Alliance | Soni DK, bioRxiv 2020 Dec;(): |
Mlkl | mixed lineage kinase domain-like | protein coding gene | MGI:1921818 | Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 Zheng M, J Biol Chem 2020 Oct 9;295(41):14040-14052 | J:296686 J:298138 | Pathology | SARS-CoV-2_virus | Treatment Mouse_Hepatitis_virus | Mlklmixed lineage kinase domain-likeprotein coding gene |
MGI | Alliance | Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 Zheng M, J Biol Chem 2020 Oct 9;295(41):14040-14052 |
Mmp14 | matrix metallopeptidase 14 (membrane-inserted) | protein coding gene | MGI:101900 | Guo X, Nat Commun 2022 Dec 23;13(1):7907 | J:333743 | SARS-CoV-2_virus | Mmp14matrix metallopeptidase 14 (membrane-inserted)protein coding gene |
MGI | Alliance | Guo X, Nat Commun 2022 Dec 23;13(1):7907 |
Mrc1 | mannose receptor, C type 1 | protein coding gene | MGI:97142 | Gao C, bioRxiv 2020 Jul 30;(): | J:296125 | SARS-CoV-2_virus | Mrc1mannose receptor, C type 1protein coding gene |
MGI | Alliance | Gao C, bioRxiv 2020 Jul 30;(): |
Muc1 | mucin 1, transmembrane | protein coding gene | MGI:97231 | Biering SB, Nat Genet 2022 Aug;54(8):1078-1089 | J:331758 | SARS-CoV-2-MA_virus | SARS-CoV-2_virus | Muc1mucin 1, transmembraneprotein coding gene |
MGI | Alliance | Biering SB, Nat Genet 2022 Aug;54(8):1078-1089 |
Muc16 | mucin 16 | protein coding gene | MGI:1920982 | Biering SB, Nat Genet 2022 Aug;54(8):1078-1089 | J:331758 | SARS-CoV-2-MA_virus | SARS-CoV-2_virus | Muc16mucin 16protein coding gene |
MGI | Alliance | Biering SB, Nat Genet 2022 Aug;54(8):1078-1089 |
Muc4 | mucin 4 | protein coding gene | MGI:2153525 | Biering SB, Nat Genet 2022 Aug;54(8):1078-1089 Plante JA, bioRxiv 2020;(): | J:331758 J:287566 | SARS-CoV-2-MA_virus | SARS-CoV-2_virus Infection | SARS-CoV-MA_virus | Sex_bias | Muc4mucin 4protein coding gene |
MGI | Alliance | Biering SB, Nat Genet 2022 Aug;54(8):1078-1089 Plante JA, bioRxiv 2020;(): |
Myd88 | myeloid differentiation primary response gene 88 | protein coding gene | MGI:108005 | Alameh MG, Immunity 2021 Dec 14;54(12):2877-2892.e7 Butchi N, J Virol 2015 Sep 15;89(18):9299-312 Cervantes-Barragan L, Blood 2007 Feb 1;109(3):1131-7 Imai Y, Cell 2008 Apr 18;133(2):235-49 Khan S, bioRxiv 2021 Mar;(): Nagai M, mBio 2021 Aug 31;12(4):e0159821 Salvi V, bioRxiv 2021 Apr;(): Salvi V, JCI Insight 2021 Sep 22;6(18):e150542 Sheahan T, PLoS Pathog 2008 Dec;4(12):e1000240 Zhao J, Proc Natl Acad Sci U S A 2014 Apr 1;111(13):4970-5 Zheng M, J Biol Chem 2020 Oct 9;295(41):14040-14052 Zheng M, Nat Immunol 2021 Jul;22(7):829-838 | J:337329 J:224849 J:144400 J:145306 J:303202 J:313440 J:304651 J:313336 J:162707 J:207380 J:298138 J:308903 | SARS-CoV-2_virus | Vaccine Infection | Mouse_Hepatitis_virus | Pathology Infection | Mouse_Hepatitis_virus | SARS-CoV_virus SARS-CoV_virus Infection | SARS-CoV-2_virus SARS-CoV-2_virus Pathology | SARS-CoV-MA_virus MERS-CoV_virus Mouse_Hepatitis_virus Pathology | SARS-CoV-2_virus | Myd88myeloid differentiation primary response gene 88protein coding gene |
MGI | Alliance | Alameh MG, Immunity 2021 Dec 14;54(12):2877-2892.e7 Butchi N, J Virol 2015 Sep 15;89(18):9299-312 Cervantes-Barragan L, Blood 2007 Feb 1;109(3):1131-7 Imai Y, Cell 2008 Apr 18;133(2):235-49 Khan S, bioRxiv 2021 Mar;(): Nagai M, mBio 2021 Aug 31;12(4):e0159821 Salvi V, bioRxiv 2021 Apr;(): Salvi V, JCI Insight 2021 Sep 22;6(18):e150542 Sheahan T, PLoS Pathog 2008 Dec;4(12):e1000240 Zhao J, Proc Natl Acad Sci U S A 2014 Apr 1;111(13):4970-5 Zheng M, J Biol Chem 2020 Oct 9;295(41):14040-14052 Zheng M, Nat Immunol 2021 Jul;22(7):829-838 |
Ncf1 | neutrophil cytosolic factor 1 | protein coding gene | MGI:97283 | Imai Y, Cell 2008 Apr 18;133(2):235-49 | J:145306 | SARS-CoV_virus | Ncf1neutrophil cytosolic factor 1protein coding gene |
MGI | Alliance | Imai Y, Cell 2008 Apr 18;133(2):235-49 |
Ndor1 | NADPH dependent diflavin oxidoreductase 1 | protein coding gene | MGI:1926047 | Strine MS, PLoS Biol 2023 Jun;21(6):e3002097 | J:341033 | Gene | MERS-CoV_virus | SARS-CoV-2_virus | SARS-CoV_virus | Ndor1NADPH dependent diflavin oxidoreductase 1protein coding gene |
MGI | Alliance | Strine MS, PLoS Biol 2023 Jun;21(6):e3002097 |
Nell1 | NEL-like 1 | protein coding gene | MGI:2443902 | Biswas R, bioRxiv 2021 Feb;(): | J:302158 | Gene | SARS-CoV-2_virus | Nell1NEL-like 1protein coding gene |
MGI | Alliance | Biswas R, bioRxiv 2021 Feb;(): |
Nfe2l2 | nuclear factor, erythroid derived 2, like 2 | protein coding gene | MGI:108420 | Qu Y, Microbiol Spectr 2023 Jun 15;11(3):e0037823 | J:357765 | Gene | Variant | VOC_B.1.1.529_Omicron | Nfe2l2nuclear factor, erythroid derived 2, like 2protein coding gene |
MGI | Alliance | Qu Y, Microbiol Spectr 2023 Jun 15;11(3):e0037823 |
Nfkb1 | nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 | protein coding gene | MGI:97312 | DeDiego ML, J Virol 2014 Jan;88(2):913-24 | J:286180 | Pathology | SARS-CoV-MA_virus | Treatment | Nfkb1nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105protein coding gene |
MGI | Alliance | DeDiego ML, J Virol 2014 Jan;88(2):913-24 |
Nlrc4 | NLR family, CARD domain containing 4 | protein coding gene | MGI:3036243 | Zheng M, J Biol Chem 2020 Oct 9;295(41):14040-14052 | J:298138 | Mouse_Hepatitis_virus | Nlrc4NLR family, CARD domain containing 4protein coding gene |
MGI | Alliance | Zheng M, J Biol Chem 2020 Oct 9;295(41):14040-14052 |
Nlrp12 | NLR family, pyrin domain containing 12 | protein coding gene | MGI:2676630 | Moustaqil M, Emerg Microbes Infect 2021 Dec;10(1):178-195 | J:304591 | Gene | SARS-CoV-2_virus | Nlrp12NLR family, pyrin domain containing 12protein coding gene |
MGI | Alliance | Moustaqil M, Emerg Microbes Infect 2021 Dec;10(1):178-195 |
Nlrp3 | NLR family, pyrin domain containing 3 | protein coding gene | MGI:2653833 | Chang YS, Int J Mol Sci 2020 Apr 30;21(9):3179 Duhalde Vega M, Sci Adv 2022 Sep 23;8(38):eabn6545 Pan P, Nat Commun 2021 Aug 2;12(1):4664 Wu J, Immunity 2021 Nov 9;54(11):2632-2649.e6 Yalcinkaya M, Sci Rep 2021 Dec 24;11(1):24432 Yang J, Nature 2020 Jul 29;(): Zeng J, EBioMedicine 2021 Dec 31;75():103803 Zheng M, J Biol Chem 2020 Oct 9;295(41):14040-14052 Zheng M, Nat Immunol 2021 Jul;22(7):829-838 | J:291870 J:331762 J:313326 J:323769 J:329139 J:292665 J:319443 J:298138 J:308903 | SARS-CoV_virus Mouse_Hepatitis_virus Pathology | SARS-CoV-2_virus Gene | Pathology SARS-CoV-2_virus | Vaccine | Nlrp3NLR family, pyrin domain containing 3protein coding gene |
MGI | Alliance | Chang YS, Int J Mol Sci 2020 Apr 30;21(9):3179 Duhalde Vega M, Sci Adv 2022 Sep 23;8(38):eabn6545 Pan P, Nat Commun 2021 Aug 2;12(1):4664 Wu J, Immunity 2021 Nov 9;54(11):2632-2649.e6 Yalcinkaya M, Sci Rep 2021 Dec 24;11(1):24432 Yang J, Nature 2020 Jul 29;(): Zeng J, EBioMedicine 2021 Dec 31;75():103803 Zheng M, J Biol Chem 2020 Oct 9;295(41):14040-14052 Zheng M, Nat Immunol 2021 Jul;22(7):829-838 |
Nos2 | nitric oxide synthase 2, inducible | protein coding gene | MGI:97361 | Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 | J:296686 | Pathology | SARS-CoV-2_virus | Treatment | Nos2nitric oxide synthase 2, inducibleprotein coding gene |
MGI | Alliance | Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 |
Notch1 | notch 1 | protein coding gene | MGI:97363 | Harb H, Immunity 2021 Apr 22;(): | J:347529 | Infection | Notch1notch 1protein coding gene |
MGI | Alliance | Harb H, Immunity 2021 Apr 22;(): |
Notch2 | notch 2 | protein coding gene | MGI:97364 | Harb H, Immunity 2021 Apr 22;(): | J:347529 | Infection | Notch2notch 2protein coding gene |
MGI | Alliance | Harb H, Immunity 2021 Apr 22;(): |
Notch3 | notch 3 | protein coding gene | MGI:99460 | Harb H, Immunity 2021 Apr 22;(): | J:347529 | Infection | Notch3notch 3protein coding gene |
MGI | Alliance | Harb H, Immunity 2021 Apr 22;(): |
Notch4 | notch 4 | protein coding gene | MGI:107471 | Harb H, Immunity 2021 Apr 22;(): | J:347529 | Infection | Notch4notch 4protein coding gene |
MGI | Alliance | Harb H, Immunity 2021 Apr 22;(): |
Nrp1 | neuropilin 1 | protein coding gene | MGI:106206 | Cantuti-Castelvetri L, Science 2020 Nov 13;370(6518):856-860 Gao J, bioRxiv 2021 Apr;(): | J:297122 J:304619 | Infection | SARS-CoV-2_virus | Nrp1neuropilin 1protein coding gene |
MGI | Alliance | Cantuti-Castelvetri L, Science 2020 Nov 13;370(6518):856-860 Gao J, bioRxiv 2021 Apr;(): |
Oas1a | 2'-5' oligoadenylate synthetase 1A | protein coding gene | MGI:2180860 | Birdwell LD, J Virol 2016 Jan 6;90(6):3160-72 | J:318622 | Mouse_Hepatitis_virus | Oas1a2'-5' oligoadenylate synthetase 1Aprotein coding gene |
MGI | Alliance | Birdwell LD, J Virol 2016 Jan 6;90(6):3160-72 |
Omp | olfactory marker protein | protein coding gene | MGI:97436 | Bilinska K, ACS Chem Neurosci 2020 Jun 3;11(11):1555-1562 Brechbuhl J, Commun Biol 2021 Jul 15;4(1):880 | J:288137 J:319436 | Infection | SARS-CoV-2_virus Gene | Ompolfactory marker proteinprotein coding gene |
MGI | Alliance | Bilinska K, ACS Chem Neurosci 2020 Jun 3;11(11):1555-1562 |
Parp12 | poly (ADP-ribose) polymerase family, member 12 | protein coding gene | MGI:2143990 | Kerr CM, J Virol 2023 Sep 28;97(9):e0088523 | J:340885 | Gene | Infection | Mouse_Hepatitis_virus | Parp12poly (ADP-ribose) polymerase family, member 12protein coding gene |
MGI | Alliance | Kerr CM, J Virol 2023 Sep 28;97(9):e0088523 |
Pdcd1 | programmed cell death 1 | protein coding gene | MGI:104879 | Phares TW, J Immunol 2009 May 1;182(9):5430-8 | J:147948 | Mouse_Hepatitis_virus | Pdcd1programmed cell death 1protein coding gene |
MGI | Alliance | Phares TW, J Immunol 2009 May 1;182(9):5430-8 |
Pdgfb | platelet derived growth factor, B polypeptide | protein coding gene | MGI:97528 | He L, bioRxiv 2020;(): | J:295372 | Infection | SARS-CoV-2_virus | Pdgfbplatelet derived growth factor, B polypeptideprotein coding gene |
MGI | Alliance | He L, bioRxiv 2020;(): |
Pla2g2d | phospholipase A2, group IID | protein coding gene | MGI:1341796 | Vijay R, J Exp Med 2015 Oct 19;212(11):1851-68 WOng LY, bioRxiv 2021 Apr;(): Zheng J, J Clin Invest 2021 Jun 1;131(11): | J:229035 J:304684 J:311966 | Infection | SARS-CoV-MA_virus SARS-CoV-2-MA_virus | Treatment Comorbidity | MERS-CoV_virus | Pla2g2dphospholipase A2, group IIDprotein coding gene |
MGI | Alliance | Vijay R, J Exp Med 2015 Oct 19;212(11):1851-68 WOng LY, bioRxiv 2021 Apr;(): Zheng J, J Clin Invest 2021 Jun 1;131(11): |
Plat | plasminogen activator, tissue | protein coding gene | MGI:97610 | Gralinski LE, mBio 2013 Aug 6;4(4): | J:288556 | Infection | Pathology | SARS-CoV-MA_virus | Platplasminogen activator, tissueprotein coding gene |
MGI | Alliance | Gralinski LE, mBio 2013 Aug 6;4(4): |
Ppp1r14c | protein phosphatase 1, regulatory inhibitor subunit 14C | protein coding gene | MGI:1923392 | McDermott JE, BMC Syst Biol 2016 Sep 23;10(1):93 | J:288523 | Pathology | SARS-CoV-MA_virus | Ppp1r14cprotein phosphatase 1, regulatory inhibitor subunit 14Cprotein coding gene |
MGI | Alliance | McDermott JE, BMC Syst Biol 2016 Sep 23;10(1):93 |
Prkdc | protein kinase, DNA activated, catalytic polypeptide | protein coding gene | MGI:104779 | Abdelnabi R, J Virol 2022 Aug 24;96(16):e0075822 Graham RL, Nat Med 2012 Dec;18(12):1820-6 Halwe S, bioRxiv 2021 Jun;(): Hu Z, bioRxiv 2021 Nov;(): Pewe L, J Virol 1997 Oct;71(10):7640-7 | J:331764 J:286309 J:308648 J:313461 J:42952 | Treatment | VOC_B.1.351_Beta SARS-CoV_virus | Vaccine SARS-CoV-2_virus | Treatment | VOC_B.1.1.7_Alpha | VOC_B.1.351_Beta Infection | SARS-CoV-2_virus Mouse_Hepatitis_virus | Prkdcprotein kinase, DNA activated, catalytic polypeptideprotein coding gene |
MGI | Alliance | Abdelnabi R, J Virol 2022 Aug 24;96(16):e0075822 Graham RL, Nat Med 2012 Dec;18(12):1820-6 Halwe S, bioRxiv 2021 Jun;(): Hu Z, bioRxiv 2021 Nov;(): Pewe L, J Virol 1997 Oct;71(10):7640-7 |
Prt4 | protease 4 | heritable phenotypic marker | MGI:97779 | Kyuwa S, Microb Pathog 1992 Feb;12(2):95-104 | J:1357 | Mouse_Hepatitis_virus | Prt4protease 4heritable phenotypic marker |
MGI | Alliance | Kyuwa S, Microb Pathog 1992 Feb;12(2):95-104 |
Prt5 | protease 5 | heritable phenotypic marker | MGI:97780 | Kyuwa S, Microb Pathog 1992 Feb;12(2):95-104 | J:1357 | Mouse_Hepatitis_virus | Prt5protease 5heritable phenotypic marker |
MGI | Alliance | Kyuwa S, Microb Pathog 1992 Feb;12(2):95-104 |
Psg16 | pregnancy specific beta-1-glycoprotein 16 | protein coding gene | MGI:1347249 | Chen DS, Proc Natl Acad Sci U S A 1995 Dec 19;92(26):12095-9 Hirai A, J Virol 2010 Jul;84(13):6654-66 | J:30292 J:198335 | Mouse_Hepatitis_virus Infection | Mouse_Hepatitis_virus | Psg16pregnancy specific beta-1-glycoprotein 16protein coding gene |
MGI | Alliance | Chen DS, Proc Natl Acad Sci U S A 1995 Dec 19;92(26):12095-9 Hirai A, J Virol 2010 Jul;84(13):6654-66 |
Psg17 | pregnancy specific beta-1-glycoprotein 17 | protein coding gene | MGI:1347250 | Chen DS, Proc Natl Acad Sci U S A 1995 Dec 19;92(26):12095-9 | J:30292 | Mouse_Hepatitis_virus | Psg17pregnancy specific beta-1-glycoprotein 17protein coding gene |
MGI | Alliance | Chen DS, Proc Natl Acad Sci U S A 1995 Dec 19;92(26):12095-9 |
Ptgdr | prostaglandin D receptor | protein coding gene | MGI:102966 | Verma AK, mBio 2021 Oct 26;12(5):e0196921 Vijay R, Proc Natl Acad Sci U S A 2017 Jul 03;114(27):E5444-E5453 WOng LY, bioRxiv 2021 Apr;(): | J:313438 J:243958 J:304684 | Mouse_Hepatitis_virus SARS-CoV-2-MA_virus | Treatment | Ptgdrprostaglandin D receptorprotein coding gene |
MGI | Alliance | Verma AK, mBio 2021 Oct 26;12(5):e0196921 Vijay R, Proc Natl Acad Sci U S A 2017 Jul 03;114(27):E5444-E5453 WOng LY, bioRxiv 2021 Apr;(): |
Ptges2 | prostaglandin E synthase 2 | protein coding gene | MGI:1917592 | McDermott JE, BMC Syst Biol 2016 Sep 23;10(1):93 | J:288523 | Pathology | SARS-CoV-MA_virus | Ptges2prostaglandin E synthase 2protein coding gene |
MGI | Alliance | McDermott JE, BMC Syst Biol 2016 Sep 23;10(1):93 |
Ptpn2 | protein tyrosine phosphatase, non-receptor type 2 | protein coding gene | MGI:97806 | Spalinger MR, bioRxiv 2020 Dec 9;(): | J:300213 | SARS-CoV-2_virus | Treatment | Ptpn2protein tyrosine phosphatase, non-receptor type 2protein coding gene |
MGI | Alliance | Spalinger MR, bioRxiv 2020 Dec 9;(): |
Ptx3 | pentraxin related gene | protein coding gene | MGI:104641 | Han B, Lab Invest 2012 Sep;92(9):1285-96 | J:188421 | Mouse_Hepatitis_virus | Ptx3pentraxin related geneprotein coding gene |
MGI | Alliance | Han B, Lab Invest 2012 Sep;92(9):1285-96 |
Pycard | PYD and CARD domain containing | protein coding gene | MGI:1931465 | Zheng M, J Biol Chem 2020 Oct 9;295(41):14040-14052 | J:298138 | Mouse_Hepatitis_virus | PycardPYD and CARD domain containingprotein coding gene |
MGI | Alliance | Zheng M, J Biol Chem 2020 Oct 9;295(41):14040-14052 |
Rag1 | recombination activating 1 | protein coding gene | MGI:97848 | Channappanavar R, J Infect Dis 2015 Dec 15;212(12):1894-903 Chen BP, J Immunol 2001 Oct 15;167(8):4585-92 Glass WG, J Immunol 2004 Sep 15;173(6):4030-9 Graham RL, Nat Med 2012 Dec;18(12):1820-6 Halwe S, bioRxiv 2021 Jun;(): Hassan AO, Cell 2020 Jun 10;(): Israelow B, bioRxiv 2021 May;(): Israelow B, Sci Immunol 2021 Oct 15;6(64):eabl4509 Johansen MD, Mucosal Immunol 2020 Aug 20;(): Mao T, bioRxiv 2021 Jun;(): Ngo VL, Cell Host Microbe 2024 Jan 23;(): Templeton SP, J Neuroimmunol 2008 Feb;194(1-2):18-26 | J:287959 J:106738 J:92752 J:286309 J:308648 J:290258 J:308733 J:331753 J:295350 J:308656 J:345954 J:131907 | MERS-CoV_virus | Treatment Mouse_Hepatitis_virus | Pathology Infection | SARS-CoV_virus SARS-CoV_virus | Vaccine SARS-CoV-2_virus | Treatment | VOC_B.1.1.7_Alpha | VOC_B.1.351_Beta Infection | SARS-CoV-2_virus | Treatment Infection | SARS-CoV-2_virus MERS-CoV-MA_virus | MERS-CoV_virus | SARS-CoV-2-MA_virus | SARS-CoV-2_virus | SARS-CoV-MA_virus | SARS-CoV_virus Treatment | VOC_B.1.1.7_Alpha | VOC_B.1.351_Beta | VOC_P.1_Gamma Infection | MERS-CoV-MA_virus Mouse_Hepatitis_virus | Rag1recombination activating 1protein coding gene |
MGI | Alliance | Channappanavar R, J Infect Dis 2015 Dec 15;212(12):1894-903 Chen BP, J Immunol 2001 Oct 15;167(8):4585-92 Glass WG, J Immunol 2004 Sep 15;173(6):4030-9 Graham RL, Nat Med 2012 Dec;18(12):1820-6 Halwe S, bioRxiv 2021 Jun;(): Hassan AO, Cell 2020 Jun 10;(): Israelow B, bioRxiv 2021 May;(): Israelow B, Sci Immunol 2021 Oct 15;6(64):eabl4509 Johansen MD, Mucosal Immunol 2020 Aug 20;(): Mao T, bioRxiv 2021 Jun;(): Ngo VL, Cell Host Microbe 2024 Jan 23;(): Templeton SP, J Neuroimmunol 2008 Feb;194(1-2):18-26 |
Rag2 | recombination activating gene 2 | protein coding gene | MGI:97849 | Mao T, bioRxiv 2021 Jun;(): Sefik E, bioRxiv 2021;(): | J:308656 J:311907 | Treatment | VOC_B.1.1.7_Alpha | VOC_B.1.351_Beta | VOC_P.1_Gamma SARS-CoV-2_virus | Rag2recombination activating gene 2protein coding gene |
MGI | Alliance | Mao T, bioRxiv 2021 Jun;(): Sefik E, bioRxiv 2021;(): |
Rapgef3 | Rap guanine nucleotide exchange factor (GEF) 3 | protein coding gene | MGI:2441741 | Xiao J, J Biol Chem 2021 Oct 19;():101315 | J:313334 | Pathology | Rapgef3Rap guanine nucleotide exchange factor (GEF) 3protein coding gene |
MGI | Alliance | |
Rbpj | recombination signal binding protein for immunoglobulin kappa J region | protein coding gene | MGI:96522 | Harb H, Immunity 2021 Apr 22;(): | J:347529 | Infection | Rbpjrecombination signal binding protein for immunoglobulin kappa J regionprotein coding gene |
MGI | Alliance | Harb H, Immunity 2021 Apr 22;(): |
Ripk3 | receptor-interacting serine-threonine kinase 3 | protein coding gene | MGI:2154952 | Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 Wenzel J, Nat Neurosci 2021 Nov;24(11):1522-1533 Zheng M, J Biol Chem 2020 Oct 9;295(41):14040-14052 | J:296686 J:323957 J:298138 | Pathology | SARS-CoV-2_virus | Treatment Pathology | SARS-CoV-2_virus | VOC_B.1.351_Beta Mouse_Hepatitis_virus | Ripk3receptor-interacting serine-threonine kinase 3protein coding gene |
MGI | Alliance | Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 Wenzel J, Nat Neurosci 2021 Nov;24(11):1522-1533 Zheng M, J Biol Chem 2020 Oct 9;295(41):14040-14052 |
Rnasel | ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent) | protein coding gene | MGI:1098272 | Birdwell LD, J Virol 2016 Jan 6;90(6):3160-72 Goldstein SA, J Virol 2017 Mar 01;91(5): Kindler E, PLoS Pathog 2017 Feb;13(2):e1006195 Thornbrough JM, mBio 2016 Mar 29;7(2):e00258 Zhang R, Proc Natl Acad Sci U S A 2013 Aug 6;110(32):13114-9 Zhao L, J Virol 2013 Aug;87(15):8408-18 | J:318622 J:239306 J:291588 J:292006 J:200706 J:346257 | Mouse_Hepatitis_virus Infection | Mouse_Hepatitis_virus HCoV-229E_virus | Mouse_Hepatitis_virus MERS-CoV_virus | Mouse_Hepatitis_virus | Rnaselribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent)protein coding gene |
MGI | Alliance | Birdwell LD, J Virol 2016 Jan 6;90(6):3160-72 Goldstein SA, J Virol 2017 Mar 01;91(5): Kindler E, PLoS Pathog 2017 Feb;13(2):e1006195 Thornbrough JM, mBio 2016 Mar 29;7(2):e00258 Zhang R, Proc Natl Acad Sci U S A 2013 Aug 6;110(32):13114-9 Zhao L, J Virol 2013 Aug;87(15):8408-18 |
Rnh1 | ribonuclease/angiogenin inhibitor 1 | protein coding gene | MGI:1195456 | Bombaci G, Life Sci Alliance 2022 Jun;5(6):e202101226 | J:331827 | SARS-CoV-2_virus | Rnh1ribonuclease/angiogenin inhibitor 1protein coding gene |
MGI | Alliance | Bombaci G, Life Sci Alliance 2022 Jun;5(6):e202101226 |
Samhd1 | SAM domain and HD domain, 1 | protein coding gene | MGI:1927468 | Tada T, Proc Natl Acad Sci U S A 2023 Jun 6;120(23):e2303509120 | J:338414 | SARS-CoV-2_virus | Treatment | VOC_B.1.1.529_Omicron | Samhd1SAM domain and HD domain, 1protein coding gene |
MGI | Alliance | Tada T, Proc Natl Acad Sci U S A 2023 Jun 6;120(23):e2303509120 |
Serpine1 | serine (or cysteine) peptidase inhibitor, clade E, member 1 | protein coding gene | MGI:97608 | Gralinski LE, mBio 2013 Aug 6;4(4): Jain KG, Am J Physiol Lung Cell Mol Physiol 2022 Nov 1;323(5):L515-L524 | J:288556 J:329972 | Infection | Pathology | SARS-CoV-MA_virus Gene | Serpine1serine (or cysteine) peptidase inhibitor, clade E, member 1protein coding gene |
MGI | Alliance | Gralinski LE, mBio 2013 Aug 6;4(4): Jain KG, Am J Physiol Lung Cell Mol Physiol 2022 Nov 1;323(5):L515-L524 |
Setdb2 | SET domain, bifurcated 2 | protein coding gene | MGI:2685139 | Melvin WJ, Proc Natl Acad Sci U S A 2021 Sep 21;118(38):e2101071118 | J:311033 | Comorbidity | Gene | Mouse_Hepatitis_virus | Setdb2SET domain, bifurcated 2protein coding gene |
MGI | Alliance | Melvin WJ, Proc Natl Acad Sci U S A 2021 Sep 21;118(38):e2101071118 |
Sftpc | surfactant associated protein C | protein coding gene | MGI:109517 | Tang AT, bioRxiv 2021 Dec;(): Tang AT, PLoS Biol 2023 Feb;21(2):e3001989 | J:315719 J:337814 | Pathology | SARS-CoV-2_virus Pathology | SARS-CoV-2_virus | VOC_B.1.1.529_Omicron | Sftpcsurfactant associated protein Cprotein coding gene |
MGI | Alliance | Tang AT, bioRxiv 2021 Dec;(): Tang AT, PLoS Biol 2023 Feb;21(2):e3001989 |
Shh | sonic hedgehog | protein coding gene | MGI:98297 | Anand G, bioRxiv 2020 Dec;(): Tang AT, bioRxiv 2021 Dec;(): Tang AT, PLoS Biol 2023 Feb;21(2):e3001989 | J:298270 J:315719 J:337814 | Pathology | SARS-CoV-2_virus Pathology | SARS-CoV-2_virus | VOC_B.1.1.529_Omicron | Shhsonic hedgehogprotein coding gene |
MGI | Alliance | Anand G, bioRxiv 2020 Dec;(): Tang AT, bioRxiv 2021 Dec;(): Tang AT, PLoS Biol 2023 Feb;21(2):e3001989 |
Sirpa | signal-regulatory protein alpha | protein coding gene | MGI:108563 | Wenzek C, iScience 2022 Dec 22;25(12):105540 | J:331693 | SARS-CoV-2_virus | Sirpasignal-regulatory protein alphaprotein coding gene |
MGI | Alliance | Wenzek C, iScience 2022 Dec 22;25(12):105540 |
Smad3 | SMAD family member 3 | protein coding gene | MGI:1201674 | Wang W, Adv Sci (Weinh) 2022 Jan;9(3):e2103248 | J:333753 | Pathology | SARS-CoV-2_virus | Smad3SMAD family member 3protein coding gene |
MGI | Alliance | Wang W, Adv Sci (Weinh) 2022 Jan;9(3):e2103248 |
Spint1 | serine protease inhibitor, Kunitz type 1 | protein coding gene | MGI:1338033 | Zmora P, J Biol Chem 2018 Sep 7;293(36):13863-13873 | J:271054 | MERS-CoV_virus | Spint1serine protease inhibitor, Kunitz type 1protein coding gene |
MGI | Alliance | Zmora P, J Biol Chem 2018 Sep 7;293(36):13863-13873 |
Sry | sex determining region of Chr Y | protein coding gene | MGI:98660 | Ensor CM, bioRxiv 2021-09;(): | J:310122 | SARS-CoV-2_virus | Srysex determining region of Chr Yprotein coding gene |
MGI | Alliance | Ensor CM, bioRxiv 2021-09;(): |
Stat1 | signal transducer and activator of transcription 1 | protein coding gene | MGI:103063 | Frieman MB, PLoS Pathog 2010 Apr 8;6(4):e1000849 Graham RL, Nat Med 2012 Dec;18(12):1820-6 Hassan AO, Cell 2020 Jun 10;(): Hogan RJ, J Virol 2004 Oct;78(20):11416-21 Johansen MD, Mucosal Immunol 2020 Aug 20;(): Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 Lassnig C, Proc Natl Acad Sci U S A 2005 Jun 7;102(23):8275-80 Lassnig C, Transgenic Res 2005 Dec;14(6):803-6 Ngo VL, Cell Host Microbe 2024 Jan 23;(): Page C, J Virol 2012 Dec;86(24):13334-49 Peng X, mBio 2010 Oct 26;1(5): Singh A, Virol Sin 2020 Jun;35(3):290-304 Sun J, Cell 2020 Jun 10;(): Venkataraman T, J Virol 2017 Jun 15;91(12): Zornetzer GA, J Virol 2010 Nov;84(21):11297-309 | J:286237 J:286309 J:290258 J:286302 J:295350 J:296686 J:99728 J:103578 J:345954 J:286337 J:276986 J:295349 J:291881 J:243599 J:164586 | Pathology | SARS-CoV-MA_virus SARS-CoV_virus | Vaccine Infection | SARS-CoV-2_virus | Treatment Infection | SARS-CoV_virus MERS-CoV-MA_virus | MERS-CoV_virus | SARS-CoV-2-MA_virus | SARS-CoV-2_virus | SARS-CoV-MA_virus | SARS-CoV_virus Pathology | SARS-CoV-2_virus | Treatment HCoV-229E_virus Infection | MERS-CoV-MA_virus Pathology | SARS-CoV_virus Infection | SARS-CoV-MA_virus MERS-CoV-MA_virus | MERS-CoV_virus | SARS-CoV-2-MA_virus | SARS-CoV-2_virus | SARS-CoV_virus Infection | Pathology | SARS-CoV-2_virus | Treatment | Stat1signal transducer and activator of transcription 1protein coding gene |
MGI | Alliance | Frieman MB, PLoS Pathog 2010 Apr 8;6(4):e1000849 Graham RL, Nat Med 2012 Dec;18(12):1820-6 Hassan AO, Cell 2020 Jun 10;(): Hogan RJ, J Virol 2004 Oct;78(20):11416-21 Johansen MD, Mucosal Immunol 2020 Aug 20;(): Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 Lassnig C, Proc Natl Acad Sci U S A 2005 Jun 7;102(23):8275-80 Lassnig C, Transgenic Res 2005 Dec;14(6):803-6 Ngo VL, Cell Host Microbe 2024 Jan 23;(): Page C, J Virol 2012 Dec;86(24):13334-49 Peng X, mBio 2010 Oct 26;1(5): Singh A, Virol Sin 2020 Jun;35(3):290-304 Sun J, Cell 2020 Jun 10;(): Venkataraman T, J Virol 2017 Jun 15;91(12): Zornetzer GA, J Virol 2010 Nov;84(21):11297-309 |
Stat3 | signal transducer and activator of transcription 3 | protein coding gene | MGI:103038 | Musiu C, Cell Death Differ 2021 Sep 13;(): | J:313338 | Pathology | SARS-CoV-2_virus | Stat3signal transducer and activator of transcription 3protein coding gene |
MGI | Alliance | Musiu C, Cell Death Differ 2021 Sep 13;(): |
Stat6 | signal transducer and activator of transcription 6 | protein coding gene | MGI:103034 | Page C, J Virol 2012 Dec;86(24):13334-49 | J:286337 | Pathology | SARS-CoV_virus | Stat6signal transducer and activator of transcription 6protein coding gene |
MGI | Alliance | Page C, J Virol 2012 Dec;86(24):13334-49 |
Sting1 | stimulator of interferon response cGAMP interactor 1 | protein coding gene | MGI:1919762 | Humphries F, Sci Immunol 2021 May 18;6(59): Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 Wu J, Immunity 2021 Nov 9;54(11):2632-2649.e6 Yang J, Nature 2020 Jul 29;(): | J:333769 J:296686 J:323769 J:292665 | SARS-CoV-2_virus | Treatment Pathology | SARS-CoV-2_virus | Treatment Gene | Pathology SARS-CoV-2_virus | Vaccine | Sting1stimulator of interferon response cGAMP interactor 1protein coding gene |
MGI | Alliance | Humphries F, Sci Immunol 2021 May 18;6(59): Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 Wu J, Immunity 2021 Nov 9;54(11):2632-2649.e6 Yang J, Nature 2020 Jul 29;(): |
Terc | telomerase RNA component | telomerase RNA gene | MGI:109558 | Sepe S, bioRxiv 2021 Jun;(): Sepe S, EMBO Rep 2022 Feb 3;23(2):e53658 | J:309195 J:326929 | Comorbidity | Gene Gene | Terctelomerase RNA componenttelomerase RNA gene |
MGI | Alliance | Sepe S, bioRxiv 2021 Jun;(): |
Terf2 | telomeric repeat binding factor 2 | protein coding gene | MGI:1195972 | Sepe S, bioRxiv 2021 Jun;(): Sepe S, EMBO Rep 2022 Feb 3;23(2):e53658 | J:309195 J:326929 | Comorbidity | Gene Gene | Terf2telomeric repeat binding factor 2protein coding gene |
MGI | Alliance | Sepe S, bioRxiv 2021 Jun;(): |
Tfrc | transferrin receptor | protein coding gene | MGI:98822 | Tang X, bioRxiv 2020 Oct;(): | J:296386 | Infection | SARS-CoV-2_virus | Tfrctransferrin receptorprotein coding gene |
MGI | Alliance | Tang X, bioRxiv 2020 Oct;(): |
Tgfb1 | transforming growth factor, beta 1 | protein coding gene | MGI:98725 | Li SW, Sci Rep 2016 May 13;6():25754 | J:291621 | SARS-CoV_virus | Tgfb1transforming growth factor, beta 1protein coding gene |
MGI | Alliance | Li SW, Sci Rep 2016 May 13;6():25754 |
Thpo | thrombopoietin | protein coding gene | MGI:101875 | Sefik E, bioRxiv 2021;(): | J:311907 | SARS-CoV-2_virus | Thpothrombopoietinprotein coding gene |
MGI | Alliance | Sefik E, bioRxiv 2021;(): |
Ticam1 | TIR domain containing adaptor molecule 1 | protein coding gene | MGI:2147032 | Imai Y, Cell 2008 Apr 18;133(2):235-49 Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 Totura AL, mBio 2015 May 26;6(3):e00638-15 Zheng M, Nat Immunol 2021 Jul;22(7):829-838 | J:145306 J:296686 J:288471 J:308903 | SARS-CoV_virus Pathology | SARS-CoV-2_virus | Treatment Infection | SARS-CoV-MA_virus Pathology | SARS-CoV-2_virus | Ticam1TIR domain containing adaptor molecule 1protein coding gene |
MGI | Alliance | Imai Y, Cell 2008 Apr 18;133(2):235-49 Karki R, bioRxiv 2021 Jan 7;184(1):149-168.e17 Totura AL, mBio 2015 May 26;6(3):e00638-15 Zheng M, Nat Immunol 2021 Jul;22(7):829-838 |
Ticam2 | TIR domain containing adaptor molecule 2 | protein coding gene | MGI:3040056 | Gralinski LE, G3 (Bethesda) 2017 Jun 7;7(6):1653-1663 Totura AL, mBio 2015 May 26;6(3):e00638-15 | J:270045 J:288471 | Pathology | SARS-CoV-MA_virus Infection | SARS-CoV-MA_virus | Ticam2TIR domain containing adaptor molecule 2protein coding gene |
MGI | Alliance | Gralinski LE, G3 (Bethesda) 2017 Jun 7;7(6):1653-1663 Totura AL, mBio 2015 May 26;6(3):e00638-15 |
Timp1 | tissue inhibitor of metalloproteinase 1 | protein coding gene | MGI:98752 | Savarin C, ASN Neuro 2013 Nov 26;5(5):e00127 | J:331803 | Mouse_Hepatitis_virus | Timp1tissue inhibitor of metalloproteinase 1protein coding gene |
MGI | Alliance | Savarin C, ASN Neuro 2013 Nov 26;5(5):e00127 |
Tiparp | TCDD-inducible poly(ADP-ribose) polymerase | protein coding gene | MGI:2159210 | Grunewald ME, J Virol 2020 Jan 17;94(3): | J:290586 | Infection | Mouse_Hepatitis_virus | TiparpTCDD-inducible poly(ADP-ribose) polymeraseprotein coding gene |
MGI | Alliance | Grunewald ME, J Virol 2020 Jan 17;94(3): |
Tlr2 | toll-like receptor 2 | protein coding gene | MGI:1346060 | Khan S, bioRxiv 2021 Mar;(): Yang J, Nature 2020 Jul 29;(): Zheng M, Nat Immunol 2021 Jul;22(7):829-838 | J:303202 J:292665 J:308903 | Infection | SARS-CoV-2_virus SARS-CoV-2_virus | Vaccine Pathology | SARS-CoV-2_virus | Tlr2toll-like receptor 2protein coding gene |
MGI | Alliance | Khan S, bioRxiv 2021 Mar;(): Yang J, Nature 2020 Jul 29;(): Zheng M, Nat Immunol 2021 Jul;22(7):829-838 |
Tlr3 | toll-like receptor 3 | protein coding gene | MGI:2156367 | Cervantes-Barragan L, Blood 2007 Feb 1;109(3):1131-7 Imai Y, Cell 2008 Apr 18;133(2):235-49 Totura AL, mBio 2015 May 26;6(3):e00638-15 | J:144400 J:145306 J:288471 | Infection | Mouse_Hepatitis_virus | SARS-CoV_virus SARS-CoV_virus Infection | SARS-CoV-MA_virus | Tlr3toll-like receptor 3protein coding gene |
MGI | Alliance | Cervantes-Barragan L, Blood 2007 Feb 1;109(3):1131-7 Imai Y, Cell 2008 Apr 18;133(2):235-49 Totura AL, mBio 2015 May 26;6(3):e00638-15 |
Tlr4 | toll-like receptor 4 | protein coding gene | MGI:96824 | Imai Y, Cell 2008 Apr 18;133(2):235-49 Khanolkar A, J Virol 2009 Sep;83(17):8946-56 Khan S, bioRxiv 2021 Mar;(): Yang J, Nature 2020 Jul 29;(): Zheng M, Nat Immunol 2021 Jul;22(7):829-838 | J:145306 J:153918 J:303202 J:292665 J:308903 | SARS-CoV_virus Mouse_Hepatitis_virus | Pathology Infection | SARS-CoV-2_virus SARS-CoV-2_virus | Vaccine Pathology | SARS-CoV-2_virus | Tlr4toll-like receptor 4protein coding gene |
MGI | Alliance | Imai Y, Cell 2008 Apr 18;133(2):235-49 Khanolkar A, J Virol 2009 Sep;83(17):8946-56 Khan S, bioRxiv 2021 Mar;(): Yang J, Nature 2020 Jul 29;(): Zheng M, Nat Immunol 2021 Jul;22(7):829-838 |
Tlr7 | toll-like receptor 7 | protein coding gene | MGI:2176882 | Cervantes-Barragan L, Blood 2007 Feb 1;109(3):1131-7 Channappanavar R, J Clin Invest 2019 Jul 29;130():3625-3639 Kindler E, PLoS Pathog 2017 Feb;13(2):e1006195 Zheng M, Nat Immunol 2021 Jul;22(7):829-838 | J:144400 J:288107 J:291588 J:308903 | Infection | Mouse_Hepatitis_virus | SARS-CoV_virus Infection | MERS-CoV-MA_virus | Treatment HCoV-229E_virus | Mouse_Hepatitis_virus Pathology | SARS-CoV-2_virus | Tlr7toll-like receptor 7protein coding gene |
MGI | Alliance | Cervantes-Barragan L, Blood 2007 Feb 1;109(3):1131-7 Channappanavar R, J Clin Invest 2019 Jul 29;130():3625-3639 Kindler E, PLoS Pathog 2017 Feb;13(2):e1006195 Zheng M, Nat Immunol 2021 Jul;22(7):829-838 |
Tlr9 | toll-like receptor 9 | protein coding gene | MGI:1932389 | Imai Y, Cell 2008 Apr 18;133(2):235-49 Lam LKM, Sci Transl Med 2021 Oct 20;13(616):eabj1008 | J:145306 J:325468 | SARS-CoV_virus SARS-CoV-2_virus | Tlr9toll-like receptor 9protein coding gene |
MGI | Alliance | Imai Y, Cell 2008 Apr 18;133(2):235-49 Lam LKM, Sci Transl Med 2021 Oct 20;13(616):eabj1008 |
Tmem41b | transmembrane protein 41B | protein coding gene | MGI:1289225 | Sun L, PLoS Pathog 2021 Dec;17(12):e1010113 | J:316472 | Gene | Mouse_Hepatitis_virus | SARS-CoV-2_virus | Tmem41btransmembrane protein 41Bprotein coding gene |
MGI | Alliance | Sun L, PLoS Pathog 2021 Dec;17(12):e1010113 |
Tmprss11a | transmembrane protease, serine 11a | protein coding gene | MGI:2684853 | Zmora P, J Biol Chem 2018 Sep 7;293(36):13863-13873 | J:271054 | MERS-CoV_virus | Tmprss11atransmembrane protease, serine 11aprotein coding gene |
MGI | Alliance | Zmora P, J Biol Chem 2018 Sep 7;293(36):13863-13873 |
Tmprss11d | transmembrane protease, serine 11d | protein coding gene | MGI:2385221 | Heurich A, J Virol 2014 Jan;88(2):1293-307 Zmora P, J Biol Chem 2018 Sep 7;293(36):13863-13873 | J:207757 J:271054 | Infection | SARS-CoV_virus MERS-CoV_virus | Tmprss11dtransmembrane protease, serine 11dprotein coding gene |
MGI | Alliance | Heurich A, J Virol 2014 Jan;88(2):1293-307 Zmora P, J Biol Chem 2018 Sep 7;293(36):13863-13873 |
Tmprss11e | transmembrane protease, serine 11e | protein coding gene | MGI:3513175 | Zmora P, J Biol Chem 2018 Sep 7;293(36):13863-13873 | J:271054 | MERS-CoV_virus | Tmprss11etransmembrane protease, serine 11eprotein coding gene |
MGI | Alliance | Zmora P, J Biol Chem 2018 Sep 7;293(36):13863-13873 |
Tmprss2 | transmembrane protease, serine 2 | protein coding gene | MGI:1354381 | Bilinska K, ACS Chem Neurosci 2020 Jun 3;11(11):1555-1562 Brechbuhl J, bioRxiv 2021 Mar;(): Brechbuhl J, Commun Biol 2021 Jul 15;4(1):880 Deng Q, bioRxiv 2020;(): Earnest JT, PLoS Pathog 2017 Jul;13(7):e1006546 Heurich A, J Virol 2014 Jan;88(2):1293-307 Iwata-Yoshikawa N, J Virol 2019 Mar 15;93(6): Li F, Nat Commun 2021 Feb 8;12(1):866 Mullick JB, Cell Mol Bioeng 2020 Jul 27;():1-11 Qiao J, Biochem Biophys Res Commun 2020 Dec 17;533(4):867-871 Sagawa T, Environ Res 2021 Apr;195():110722 Sarver DC, Biochem Biophys Res Commun 2021 Jan 29;538():92-96 Shapira T, bioRxiv 2021 May;(): Song J, J Med Virol 2020 Nov;92(11):2556-2566 Vo T, bioRxiv 2020 Nov;(): Ziegler CGK, Cell 2020 May 28;181(5):1016-1035.e19 | J:288137 J:303458 J:319436 J:296182 J:246218 J:207757 J:283077 J:303471 J:294026 J:299392 J:305462 J:309632 J:308716 J:300096 J:296710 J:291435 | Infection | SARS-CoV-2_virus Gene SARS-CoV-2_virus | Sex_bias Infection | MERS-CoV_virus Infection | SARS-CoV_virus MERS-CoV-MA_virus | MERS-CoV_virus | Pathology SARS-CoV-2_virus | Treatment SARS-CoV-2_virus | SARS-CoV_virus Comorbidity | Gene Comorbidity SARS-CoV-2_virus | Treatment | VOC_B.1.1.7_Alpha | VOC_B.1.351_Beta Infection Pathology | SARS-CoV-2_virus | Tmprss2transmembrane protease, serine 2protein coding gene |
MGI | Alliance | Bilinska K, ACS Chem Neurosci 2020 Jun 3;11(11):1555-1562 Brechbuhl J, bioRxiv 2021 Mar;(): Brechbuhl J, Commun Biol 2021 Jul 15;4(1):880 Deng Q, bioRxiv 2020;(): Earnest JT, PLoS Pathog 2017 Jul;13(7):e1006546 Heurich A, J Virol 2014 Jan;88(2):1293-307 Iwata-Yoshikawa N, J Virol 2019 Mar 15;93(6): Li F, Nat Commun 2021 Feb 8;12(1):866 Mullick JB, Cell Mol Bioeng 2020 Jul 27;():1-11 Qiao J, Biochem Biophys Res Commun 2020 Dec 17;533(4):867-871 Sagawa T, Environ Res 2021 Apr;195():110722 Sarver DC, Biochem Biophys Res Commun 2021 Jan 29;538():92-96 Shapira T, bioRxiv 2021 May;(): Song J, J Med Virol 2020 Nov;92(11):2556-2566 Vo T, bioRxiv 2020 Nov;(): Ziegler CGK, Cell 2020 May 28;181(5):1016-1035.e19 |
Tmprss4 | transmembrane protease, serine 4 | protein coding gene | MGI:2384877 | Bilinska K, ACS Chem Neurosci 2020 Jun 3;11(11):1555-1562 | J:288137 | Infection | SARS-CoV-2_virus | Tmprss4transmembrane protease, serine 4protein coding gene |
MGI | Alliance | Bilinska K, ACS Chem Neurosci 2020 Jun 3;11(11):1555-1562 |
Tnf | tumor necrosis factor | protein coding gene | MGI:104798 | Xu H, Immunol Lett 2014 Mar-Apr;158(1-2):25-32 | J:315532 | Mouse_Hepatitis_virus | Tnftumor necrosis factorprotein coding gene |
MGI | Alliance | Xu H, Immunol Lett 2014 Mar-Apr;158(1-2):25-32 |
Tnfrsf1a | tumor necrosis factor receptor superfamily, member 1a | protein coding gene | MGI:1314884 | McDermott JE, BMC Syst Biol 2016 Sep 23;10(1):93 Xu H, Immunol Lett 2014 Mar-Apr;158(1-2):25-32 | J:288523 J:315532 | Pathology | SARS-CoV-MA_virus Mouse_Hepatitis_virus | Tnfrsf1atumor necrosis factor receptor superfamily, member 1aprotein coding gene |
MGI | Alliance | McDermott JE, BMC Syst Biol 2016 Sep 23;10(1):93 Xu H, Immunol Lett 2014 Mar-Apr;158(1-2):25-32 |
Tnfrsf1b | tumor necrosis factor receptor superfamily, member 1b | protein coding gene | MGI:1314883 | McDermott JE, BMC Syst Biol 2016 Sep 23;10(1):93 Xu H, Immunol Lett 2014 Mar-Apr;158(1-2):25-32 | J:288523 J:315532 | Pathology | SARS-CoV-MA_virus Mouse_Hepatitis_virus | Tnfrsf1btumor necrosis factor receptor superfamily, member 1bprotein coding gene |
MGI | Alliance | McDermott JE, BMC Syst Biol 2016 Sep 23;10(1):93 Xu H, Immunol Lett 2014 Mar-Apr;158(1-2):25-32 |
Tpe1 | tear protein electrophoretic 1 | unclassified gene | MGI:103146 | Kyuwa S, Microb Pathog 1992 Feb;12(2):95-104 | J:1357 | Mouse_Hepatitis_virus | Tpe1tear protein electrophoretic 1unclassified gene |
MGI | Alliance | Kyuwa S, Microb Pathog 1992 Feb;12(2):95-104 |
Traf3 | TNF receptor-associated factor 3 | protein coding gene | MGI:108041 | Lui PY, Emerg Microbes Infect 2016 Apr 20;5():e39 | J:296106 | Gene | Infection | MERS-CoV_virus | Traf3TNF receptor-associated factor 3protein coding gene |
MGI | Alliance | Lui PY, Emerg Microbes Infect 2016 Apr 20;5():e39 |
Traf3ip2 | TRAF3 interacting protein 2 | protein coding gene | MGI:2143599 | Lin X, iScience 2021 Apr 23;24(4):102293 | J:304178 | Pathology | SARS-CoV-2_virus | Treatment | Traf3ip2TRAF3 interacting protein 2protein coding gene |
MGI | Alliance | Lin X, iScience 2021 Apr 23;24(4):102293 |
Traf6 | TNF receptor-associated factor 6 | protein coding gene | MGI:108072 | Imai Y, Cell 2008 Apr 18;133(2):235-49 | J:145306 | SARS-CoV_virus | Traf6TNF receptor-associated factor 6protein coding gene |
MGI | Alliance | Imai Y, Cell 2008 Apr 18;133(2):235-49 |
Trem2 | triggering receptor expressed on myeloid cells 2 | protein coding gene | MGI:1913150 | Hwang M, J Neuroinflammation 2022 Nov 4;19(1):267 Wu Y, Sci Adv 2021 Dec 10;7(50):eabi6802 | J:331755 J:320018 | Mouse_Hepatitis_virus Gene | Mouse_Hepatitis_virus | SARS-CoV-2_virus | Trem2triggering receptor expressed on myeloid cells 2protein coding gene |
MGI | Alliance | Hwang M, J Neuroinflammation 2022 Nov 4;19(1):267 Wu Y, Sci Adv 2021 Dec 10;7(50):eabi6802 |
Trim14 | tripartite motif-containing 14 | protein coding gene | MGI:1921985 | Schafer A, bioRxiv 2021 May;(): | J:308730 | Pathology | SARS-CoV-2-MA_virus | SARS-CoV-2_virus | SARS-CoV-MA_virus | SARS-CoV_virus | Trim14tripartite motif-containing 14protein coding gene |
MGI | Alliance | Schafer A, bioRxiv 2021 May;(): |
Trim55 | tripartite motif-containing 55 | protein coding gene | MGI:3036269 | Gralinski LE, PLoS Genet 2015 Oct;11(10):e1005504 | J:268979 | Infection | SARS-CoV-MA_virus | Trim55tripartite motif-containing 55protein coding gene |
MGI | Alliance | Gralinski LE, PLoS Genet 2015 Oct;11(10):e1005504 |
Trp53 | transformation related protein 53 | protein coding gene | MGI:98834 | Zhou B, J Virol 2008 Jul;82(14):6962-71 | J:289079 | SARS-CoV_virus | Trp53transformation related protein 53protein coding gene |
MGI | Alliance | Zhou B, J Virol 2008 Jul;82(14):6962-71 |
Trpv2 | transient receptor potential cation channel, subfamily V, member 2 | protein coding gene | MGI:1341836 | Xu J, Theranostics 2021;11(15):7379-7390 | J:314372 | Infection | Trpv2transient receptor potential cation channel, subfamily V, member 2protein coding gene |
MGI | Alliance | |
Tyr | tyrosinase | protein coding gene | MGI:98880 | Scaglione A, Front Immunol 2021;12():719077 | J:335910 | SARS-CoV-2_virus | Treatment | Vaccine | Tyrtyrosinaseprotein coding gene |
MGI | Alliance | Scaglione A, Front Immunol 2021;12():719077 |
Usp10 | ubiquitin specific peptidase 10 | protein coding gene | MGI:894652 | Luo Y, Signal Transduct Target Ther 2022 Jan 4;7(1):7 | J:333746 | SARS-CoV-2_virus | Vaccine | Usp10ubiquitin specific peptidase 10protein coding gene |
MGI | Alliance | Luo Y, Signal Transduct Target Ther 2022 Jan 4;7(1):7 |
Usp18 | ubiquitin specific peptidase 18 | protein coding gene | MGI:1344364 | Ma XZ, J Virol 2014 Jun;88(11):6195-204 | J:214425 | Mouse_Hepatitis_virus | Usp18ubiquitin specific peptidase 18protein coding gene |
MGI | Alliance | Ma XZ, J Virol 2014 Jun;88(11):6195-204 |
Vhl | von Hippel-Lindau tumor suppressor | protein coding gene | MGI:103223 | Kotagiri P, EBioMedicine 2022 Feb 18;77():103878 | J:322643 | SARS-CoV-2_virus | Vhlvon Hippel-Lindau tumor suppressorprotein coding gene |
MGI | Alliance | Kotagiri P, EBioMedicine 2022 Feb 18;77():103878 |
Wwtr1 | WW domain containing transcription regulator 1 | protein coding gene | MGI:1917649 | Harb H, Immunity 2021 Apr 22;(): | J:347529 | Infection | Wwtr1WW domain containing transcription regulator 1protein coding gene |
MGI | Alliance | Harb H, Immunity 2021 Apr 22;(): |
Yap1 | yes-associated protein 1 | protein coding gene | MGI:103262 | Harb H, Immunity 2021 Apr 22;(): | J:347529 | Infection | Yap1yes-associated protein 1protein coding gene |
MGI | Alliance | Harb H, Immunity 2021 Apr 22;(): |
Yif1b | Yip1 interacting factor homolog B (S. cerevisiae) | protein coding gene | MGI:1924504 | Lin X, bioRxiv 2021 Dec;(): | J:315744 | Gene | Pathology | SARS-CoV-2_virus | Yif1bYip1 interacting factor homolog B (S. cerevisiae)protein coding gene |
MGI | Alliance | Lin X, bioRxiv 2021 Dec;(): |
Zmpste24 | zinc metallopeptidase, STE24 | protein coding gene | MGI:1890508 | Shilagardi K, mBio 2022 Oct 26;13(5):e0254322 | J:331759 | Mouse_Hepatitis_virus | Zmpste24zinc metallopeptidase, STE24protein coding gene |
MGI | Alliance | Shilagardi K, mBio 2022 Oct 26;13(5):e0254322 |
Human Genes Associated with Coronavirus Infection and Pathology
1-hgnc | 2-humangene | 3-assoctype | 4-doid | 5-doterm | 6-refid | 7-source | 8-mgisymbol | 9-mgiid | Gene Symbol | Disease | References | Mouse Ortholog |
---|---|---|---|---|---|---|---|---|---|---|---|---|
HGNC:9071 | PLG | is_implicated_in | DOID:0080600 | COVID-19 | PMID:32275753 | RGD | MGI:97620 | Plg | PLG |
COVID-19 | PMID:32275753 | Plg |
HGNC:5434 | IFNB1 | is_implicated_in | DOID:0080600 | COVID-19 | PMID:32401715 | RGD | MGI:107657 | Ifnb1 | IFNB1 |
COVID-19 | PMID:32401715 | Ifnb1 |
HGNC:13557 | ACE2 | is_implicated_in | DOID:0080600 DOID:2945 | COVID-19 severe acute respiratory syndrome | PMID:34668775 PMID:34668780 PMID:32380511 PMID:32220422 PMID:17974127 PMID:32553273 | RGD | MGI:1917258 | Ace2 | ACE2 |
COVID-19 severe acute respiratory syndrome | PMID:34668775 PMID:34668780 PMID:32380511 PMID:32220422 PMID:17974127 PMID:32553273 | Ace2 |
HGNC:18363 | IFNL1 | is_implicated_in | DOID:0080600 | COVID-19 | PMID:32854108 | RGD | MGI:2450574 MGI:3647279 | Ifnl3 Ifnl2 | IFNL1 |
COVID-19 | PMID:32854108 | Ifnl3 Ifnl2 |
HGNC:3009 | DPP4 | is_implicated_in | DOID:0080642 | Middle East respiratory syndrome | PMID:31838832 PMID:30256968 PMID:30626685 | RGD | MGI:94919 | Dpp4 | DPP4 |
Middle East respiratory syndrome | PMID:31838832 PMID:30256968 PMID:30626685 | Dpp4 |
HGNC:2707 | ACE | is_implicated_in is_not_implicated_in | DOID:0080599 DOID:0080600 | Coronavirus infectious disease COVID-19 | PMID:17108019 PMID:32386188 PMID:32286246 | RGD | MGI:87874 | Ace | ACE |
Coronavirus infectious disease COVID-19 | PMID:17108019 PMID:32386188 PMID:32286246 | Ace |
HGNC:336 | AGTR1 | is_implicated_in | DOID:0080600 | COVID-19 | PMID:32228222 | RGD | MGI:87965 MGI:87964 | Agtr1b Agtr1a | AGTR1 |
COVID-19 | PMID:32228222 | Agtr1b Agtr1a |
HGNC:1641 | CD209 | is_implicated_in | DOID:0080599 | Coronavirus infectious disease | PMID:20864747 | RGD | MGI:2157945 MGI:2157942 MGI:1916415 MGI:2157948 MGI:2157947 | Cd209c Cd209a Cd209b Cd209e Cd209d | CD209 |
Coronavirus infectious disease | PMID:20864747 | Cd209c Cd209a Cd209b Cd209e Cd209d |
HGNC:15631 | TLR7 | is_implicated_in | DOID:0080600 | COVID-19 | PMID:33650967 | RGD | MGI:2176882 | Tlr7 | TLR7 |
COVID-19 | PMID:33650967 | Tlr7 |
HGNC:9075 | SERPINF2 | is_implicated_in | DOID:0080600 | COVID-19 | PMID:32747830 | RGD | MGI:107173 | Serpinf2 | SERPINF2 |
COVID-19 | PMID:32747830 | Serpinf2 |
HGNC:1228 | SERPING1 | is_implicated_in | DOID:0080600 | COVID-19 | PMID:32747830 | RGD | MGI:894696 | Serping1 | SERPING1 |
COVID-19 | PMID:32747830 | Serping1 |
HGNC:4948 | HLA-DRB1 | is_implicated_in | DOID:2945 | severe acute respiratory syndrome | PMID:19445991 PMID:15243926 | RGD | MGI:95902 MGI:95901 | H2-Eb2 H2-Eb1 | HLA-DRB1 |
severe acute respiratory syndrome | PMID:19445991 PMID:15243926 | H2-Eb2 H2-Eb1 |
HGNC:5438 | IFNG | is_implicated_in | DOID:2945 | severe acute respiratory syndrome | PMID:19258635 PMID:16672072 | RGD | MGI:107656 | Ifng | IFNG |
severe acute respiratory syndrome | PMID:19258635 PMID:16672072 | Ifng |
HGNC:4641 | GSTT1 | is_implicated_in | DOID:0080600 | COVID-19 | PMID:32454047 | RGD | MGI:107379 | Gstt1 | GSTT1 |
COVID-19 | PMID:32454047 | Gstt1 |
HGNC:4932 | HLA-B | is_implicated_in | DOID:0080600 DOID:2945 | COVID-19 severe acute respiratory syndrome | PMID:32424945 PMID:12969506 PMID:15243926 | RGD | MGI:2687364 MGI:1276525 MGI:95912 MGI:1276570 MGI:1276527 MGI:1276526 MGI:95896 MGI:95913 MGI:95917 MGI:1276524 MGI:95904 MGI:95936 MGI:95928 MGI:95959 MGI:2676637 MGI:95935 MGI:1276522 MGI:95931 MGI:95933 MGI:95929 MGI:95956 MGI:95914 MGI:95942 | H2-M10.6 H2-M10.2 H2-L H2-M9 H2-M10.4 H2-M10.5 H2-D1 H2-M1 H2-M5 H2-M10.3 H2-K1 H2-Q7 H2-Q1 H2-T3 H2-M11 H2-Q6 H2-M10.1 H2-Q2 H2-Q4 H2-Q10 H2-T22 H2-M2 H2-T10 | HLA-B |
COVID-19 severe acute respiratory syndrome | PMID:32424945 PMID:12969506 PMID:15243926 | H2-M10.6 H2-M10.2 H2-L H2-M9 H2-M10.4 H2-M10.5 H2-D1 H2-M1 H2-M5 H2-M10.3 H2-K1 H2-Q7 H2-Q1 H2-T3 H2-M11 H2-Q6 H2-M10.1 H2-Q2 H2-Q4 H2-Q10 H2-T22 H2-M2 H2-T10 |
HGNC:6340 | KIR3DS1 | is_implicated_in | DOID:0080600 | COVID-19 | PMID:33928374 | RGD | MGI:2652397 MGI:3612791 | Kir3dl1 Kir3dl2 | KIR3DS1 |
COVID-19 | PMID:33928374 | Kir3dl1 Kir3dl2 |
HGNC:4933 | HLA-C | is_implicated_in | DOID:0080600 | COVID-19 | PMID:32424945 | RGD | MGI:2687364 MGI:1276525 MGI:95912 MGI:1276570 MGI:1276527 MGI:1276526 MGI:95896 MGI:95913 MGI:95917 MGI:1276524 MGI:95904 MGI:95936 MGI:95928 MGI:95959 MGI:2676637 MGI:95935 MGI:1276522 MGI:95931 MGI:95933 MGI:95929 MGI:95956 MGI:95914 MGI:95942 | H2-M10.6 H2-M10.2 H2-L H2-M9 H2-M10.4 H2-M10.5 H2-D1 H2-M1 H2-M5 H2-M10.3 H2-K1 H2-Q7 H2-Q1 H2-T3 H2-M11 H2-Q6 H2-M10.1 H2-Q2 H2-Q4 H2-Q10 H2-T22 H2-M2 H2-T10 | HLA-C |
COVID-19 | PMID:32424945 | H2-M10.6 H2-M10.2 H2-L H2-M9 H2-M10.4 H2-M10.5 H2-D1 H2-M1 H2-M5 H2-M10.3 H2-K1 H2-Q7 H2-Q1 H2-T3 H2-M11 H2-Q6 H2-M10.1 H2-Q2 H2-Q4 H2-Q10 H2-T22 H2-M2 H2-T10 |
HGNC:6922 | MBL2 | is_implicated_in | DOID:0080599 | Coronavirus infectious disease | PMID:15838797 | RGD | MGI:96924 | Mbl2 | MBL2 |
Coronavirus infectious disease | PMID:15838797 | Mbl2 |
HGNC:5414 | IFITM3 | is_implicated_in | DOID:0080600 | COVID-19 | PMID:32348495 | RGD | MGI:1933382 MGI:1913391 MGI:1921732 | Ifitm2 Ifitm3 Ifitm7 | IFITM3 |
COVID-19 | PMID:32348495 | Ifitm2 Ifitm3 Ifitm7 |
HGNC:13523 | CLEC4M | is_implicated_in is_not_implicated_in | DOID:2945 | severe acute respiratory syndrome | PMID:16369534 PMID:18708672 PMID:17534355 PMID:17534354 | RGD | MGI:2157942 MGI:1916415 | Cd209a Cd209b | CLEC4M |
severe acute respiratory syndrome | PMID:16369534 PMID:18708672 PMID:17534355 PMID:17534354 | Cd209a Cd209b |
HGNC:1325 | C4BPA | is_implicated_in | DOID:0080600 | COVID-19 | PMID:32747830 | RGD | MGI:88229 MGI:104965 | C4bp Zp3r | C4BPA |
COVID-19 | PMID:32747830 | C4bp Zp3r |
HGNC:79 | ABO | is_implicated_in | DOID:0080600 DOID:2945 | COVID-19 severe acute respiratory syndrome | PMID:32379894 PMID:15784866 | RGD | MGI:2135738 | Abo | ABO |
COVID-19 severe acute respiratory syndrome | PMID:32379894 PMID:15784866 | Abo |
HGNC:1328 | C4BPB | is_implicated_in | DOID:0080600 | COVID-19 | PMID:32747830 | RGD | C4BPB |
COVID-19 | PMID:32747830 | |||
HGNC:4883 | CFH | is_implicated_in | DOID:0080600 | COVID-19 | PMID:32747830 | RGD | MGI:3646434 MGI:88385 | Cfhr4 Cfh | CFH |
COVID-19 | PMID:32747830 | Cfhr4 Cfh |
HGNC:1318 | C3 | is_implicated_in | DOID:0080600 | COVID-19 | PMID:32747830 | RGD | MGI:88227 | C3 | C3 |
COVID-19 | PMID:32747830 | C3 |
HGNC:10632 | CCL5 | is_implicated_in | DOID:2945 | severe acute respiratory syndrome | PMID:19258635 | RGD | MGI:98262 | Ccl5 | CCL5 |
severe acute respiratory syndrome | PMID:19258635 | Ccl5 |
HGNC:3541 | F3 | is_implicated_in | DOID:0080600 | COVID-19 | PMID:32747830 | RGD | MGI:88381 | F3 | F3 |
COVID-19 | PMID:32747830 | F3 |
HGNC:7 | A2M | is_implicated_in | DOID:0080600 | COVID-19 | PMID:32747830 | RGD | MGI:2449119 | A2m | A2M |
COVID-19 | PMID:32747830 | A2m |
About SARS-CoV-2
SARS-CoV-2 is positive single strand RNA virus and is a member of the Coronaviridae family of viruses which are known to target the respiratory systems of mammals.
There are four genera within Coronaviridae: alpha, beta, delta, and gamma. Only alpha and beta genera are transmissible to humans.
Although the genome of SARS-CoV-2 is similar to the zoonotic coronaviruses SARs-CoV and MERS-CoV that caused the SARs outbreak of 2003 and the MERS outbreak of 2012, the emerging evidence suggests that SARS-CoV-2 did not descend from SARS-CoV. SARS-CoV-2 causes a different range of diseases in humans and has a different transmission efficiency.
SARS-CoV-2 was likely transmitted to humans from an animal reservoir. The exact nature of this transmission is still under investigation.
Other Research Resources With Special Coronavirus Information
-
Model Organisms
-
Ontologies
-
Clinical Data
-
Epidemiology
-
Molecular Data
-
Treatments & Vaccines
-
Coronavirus Biology
Model Organisms
Additional Mouse & Other Model Organism Resources
- Alliance of Genome Resources Model Organism Databases Relevant to COVID-19 Research
- Charles River Laboratories Support for Your COVID-19 Research
- Cam-Su Genomic Resource Center COVID-19 Services
- Envigo Research Tools to Combat COVID-19
- GMMCC Global Mouse Models For COVID-19 Consortium
- Infrafrontier: COVID-19 Resources and Measures
- International Mouse Phenotyping Consortium (IMPC)
- MMRRC Mouse Models for COVID-19 Research
- National Center for Advancing Translational Sciences (NCATS) Animal Model Summary Overview, OpenData COVID-19 Portal
- Rat Genome Database (RGD) COVID-19 Resources
- RIKEN BioResource Research Center (RIKEN BRC) COVID-19 Related Mouse Resources
- Taconic Biosciences Coronavirus (COVID-19) Toolkit
- The Jackson Laboratory: Coronavirus Information
Ontologies
Biomedical Ontologies & Vocabularies
- CIDO: Ontology of Coronavirus Infectious Disease
- CODO COVID-19 Ontology for Cases and Patient information
- COVID-19 Surveillance Ontology COVID19
- Human Disease Ontology (DO) terms for Coronavirus infectious disease
- Gene Ontology (GO) terms for SARS-CoV-2/COVID-19
- Homeostasis Imbalance Process Ontology (HOIP)
- COVID-19 Infectious Disease Ontology (IDO-COVID- 19)
- Logical Observation Identifiers Names and Codes for SARS-CoV-2/COVID-19 (LOINC)
- COVID-19 and SARS-CoV-2 MeSH Terms
- Protein Ontology (PRO) terms for SARS-CoV-2 proteins
- SNOMED CT COVID-19 Related Content
Epidemiology
Epidemiology & COVID-19 Situation Reports
- Chinese Center for Disease Control and Prevention (CCDC): Tracking the Epidemic (2021)
- European Centre for Disease Prevention and Control (ECDC) COVID-19 Situation Dashboard: Cases in Europe and Worldwide
- Global cases of COVID-19 from The Johns Hopkins University
- NextStrain visualization of the genomic epidemiology of novel coronavirus
- Pan American Health Organization (PAHO) COVID-19 Situation Reports
- US Centers for Disease Control and Prevention (CDC COVID-19 Data Tracker) COVID Maps, Charts, and Data
- World Health Organization (WHO) Coronavirus Disease (COVID-19) Dashboard
Molecular Data
Genes, Molecular Interactions, Pathways & Networks
- COVID-19 Data Portal from Europe
- COVID-19 Data Portal from Japan
- COVID-19 Disease Map: SARS-CoV-2 Virus-Host Interactions
- The COVID-19 Host Genetics Initiative (COVID-19 hg)
- GENCODE: Human Protein-coding Genes Linked to SARS-CoV-2/COVID-19
- OncoMX: COVID-19 Biomarkers Database
- PAGER-CoV: Pathways, Annotated Gene-Lists, and Gene Signatures Related to Coronavirus Diseases
- Protein Data Bank in Europe Knowledge Base (PDBe-KB): COVID-19 Data Portal
- Reactome SARS-CoV Infection Pathways
- UniProt Portal for SARS-CoV-2 Proteins & Receptors
- WikiPathways: COVID-19 Pathways Portal
Treatments & Vaccines
Treatments, Therapeutic Interventions & Vaccines
- Cov19VaxKB: COVID-19 Vaccine Knowledge Base
- DRUGS4COVID
- Global Health Drug Discovery Institute (GHDDI): Targeting COVID-19 Portal
- National Institutes of Health (NIH) Treatments & Vaccines for COVID-19
- Regulatory Affairs Professionals Society (RAPS): COVID-19 Vaccine Tracker
- The New York Times Coronavirus Vaccine Tracker
- US (CDC COVID Data Tracker) Vaccination Data
- WHO Draft Landscape of COVID-19 Candidate Vaccines
Coronavirus Biology
Genome Organization, Sequence Resources, Phylogeny & Taxonomy
- EBI's NCBI Organismal Classification (NCBITaxon) for Coronaviridae from Ontology Lookup Service (OLS)
- Elsevier Novel Coronavirus Resource Directory
- ICTV: International Committee on Taxonomy of Viruses
- National Center for Biotechnology Information (NCBI) SARS-CoV-2 Resources
- NCBI Taxonomy Browser
- NextStrain Phylogeny of SARS-like betacoronaviruses
- PDB-101 Molecular Landscapes by David S. Goodsell
- Viralzone SARS-CoV-2 Circulating Variants
Mice In The News
Delayed antibody treatment may improve efficacy of mRNA vaccines
Investigators led by Pablo Penaloza-MacMaster, Ph.D., associate professor of Microbiology-Immunology, have discovered that administering an antibody treatment four days after mRNA…
Read at medicalxpress.comRepeated COVID vaccines enhance mucosal immunity against the virus
Part of the global response strategy against the COVID pandemic involves the administration of booster shots, or ‘vaccine updates’ to ensure protection against new variants…
Read at vib.beInflammation in severe COVID linked to bad fungal microbiome
An imbalance of fungi in the gut could contribute to excessive inflammation in people with severe COVID-19 or long COVID. A study found that individuals with severe disease had elevated …
Read at nature.comNovel Antibody Platform Tackles Viral Mutations
Scientists at the Icahn School of Medicine at Mount Sinai, in collaboration with colleagues in the field, have developed an innovative antibody platform aimed at tackling one of the greatest challenges in treating rapidly evolving…
Read at mountsinai.orgSynthetic peptide acts as molecular shield to prevent SARS-CoV-2 from infecting cells
A peptide synthesized by researchers at the University of São Paulo (USP) in Brazil protected human lung cells against infection …
Read at medicalxpress.comNew humanized mouse models created to study COVID-19
Scientists at La Jolla Institute for Immunology (LJI) have developed six lines of humanized mice that can serve as valuable models for studying human cases of COVID-19.
Read at news-medical.net2024 News
- MedicalXpress “Delayed antibody treatment may improve efficacy of mRNA vaccines” (October 28, 2024)
- Vlaams Instituut voor Biotechnologie “Repeated COVID vaccines enhance mucosal immunity against the virus” (October 24, 2024)
- Nature News “Inflammation in severe COVID linked to bad fungal microbiome” (October 23, 2024)
- Mount Sinai Health System “Novel Antibody Platform Tackles Viral Mutations” (October 23, 2024)
- MedicalXpress “Synthetic peptide acts as molecular shield to prevent SARS-CoV-2 from infecting cells” (October 2, 2024)
- La Jolla Institute for Immunology “New mouse models offer valuable window into COVID-19 infection” (October 1, 2024)
- News Medical Life Sciences “New humanized mouse models created to study COVID-19” (October 1, 2024)
- MedicalXpress “COVID-induced immune memory could protect against severe cases of flu, mouse study suggests” (September 30, 2024)
- The Rockefeller University “Could a bout of COVID protect you from a severe case of flu?” (September 30, 2024)
- News Medical Life Sciences “Chemical genetics uncovers promising anti-COVID compounds” (September 25, 2024)
- The Hindu “Mice study claims to have found long COVID’s ‘real’ perpetrator” (September 9, 2024)
- Northwestern University Feinberg News Center “Spike Mutations Help SARS-CoV-2 Infect the Brain” (September 9, 2024)
- Texas Biomedical Research Institute “Monoclonal antibody shows protection against all COVID variants” (September 5, 2024)
- University of Virginia Health “Cause, Potential Treatment ID’d for Persistent COVID-19 Lung Problems” (September 5, 2024)
- Georgia State University “Study: Late Start of COVID Treatment May Still Benefit Immunocompromised Patients” (September 3, 2024)
- News Medical Life Sciences “Intranasal vaccine shows broad SARS-CoV-2 variant protection” (September 1, 2024)
- News Medical Life Sciences “Fibrin fuels thromboinflammation and brain damage in COVID-19” (August 29, 2024)
- Gladstone Institutes “Discovery of How Blood Clots Harm Brain and Body in COVID-19 Points to New Therapy” (August 28, 2024)
- News Medical Life Sciences “SARS-CoV-2 evolves differently in the brain, revealing critical insights into viral tropism” (August 27, 2024)
- Griffith University News “Game-changing needle-free COVID-19 intranasal vaccine” (August 27, 2024)Live Science “Virus that causes COVID-19 uses a secret back door to infect the brain” (August 23, 2024)
- Technology Networks “SARS-CoV-2 Mutation Enhances Brain Infection, Potentially Explaining Long COVID” (August 23, 2024)
- News Medical Life Sciences “Mutation in SARS-CoV-2 spike protein enhances brain infection” (August 23, 2024)
- New Scientist “Intestinal parasites may reduce covid-19 vaccine effectiveness” (August 21, 2024)
- News Medical Life Sciences “New fluorescent probe offers non-invasive detection of smell loss” (August 20, 2024)
- University of Virginia Health “Arthritis Drugs May Relieve Long COVID Lung Symptoms” (July 30, 2024)
- News Medical Life Sciences “UVA researchers identify a potential treatment for respiratory symptoms of long COVID” (July 30, 2024)
- Yale School of Medicine “New Evidence Supports Autoimmunity as One of Long COVID’s Underlying Drivers” (July 22, 2024)
- Nature News “Long COVID lung damage linked to immune system response” (July 18, 2024)
- Science News “Rogue antibodies may cause some long COVID symptoms” (July 16, 2024)
- Fierce Biotech “Drug prevents COVID symptoms in mice by protecting mitochondria, without resistance risk” (July 16, 2024)
- News Medical Life Sciences “Mitochondrially-targeted antioxidants could reduce SARS-CoV-2 effects across multiple organs” (July 15, 2024)
- News Medical Life Sciences “Study reveals how inflammation weakens muscles during illness” (July 13, 2024)
- Washington University School of Medicine in St. Louis “Brain inflammation triggers muscle weakness after infections” (July 12, 2024)
- MedicalXpress.com “Scientists identify possible way to block muscle fatigue in long COVID, other diseases” (July 12, 2024)
- Live Science “Scientists breed most human-like mice yet” (July 12, 2024)
- Fierce Biotech “Active vaccine adjuvant boosts COVID-19 and flu antibodies in mice” (July 9, 2024)
- MedicineNet “Could a Cancer Drug Curb the Organ Damage of Severe COVID?” (July 8, 2024)
- News Medical Life Sciences “Breakthrough humanized mouse model offers new insights for immunotherapy development” (July 5, 2024)
- UT Health San Antonio “Scientists create first mouse model with complete, functional human immune system” (July 5, 2024)
- News Medical Life Sciences “Repurposing cancer drug to prevent organ damage in infectious diseases” (July 3, 2024)
- UC San Diego “Fighting COVID-19 With a Cancer Drug” (July 3, 2024)
- Western University Ontario “Research team finds vaccination may reduce memory loss from COVID-19 infections” (June 27, 2024)
- MedicalXpress.com “Vaccination may reduce memory loss from COVID-19 infections” (June 27, 2024)
- Science.org “Antibodies from Long Covid patients prompt symptoms in mice” (June 21, 2024)
- Nature.com “What causes long COVID? Case builds for rogue antibodies” (June 13, 2024)
- Fortune.com “COVID can seriously damage your vision, even if you didn’t have symptoms, new study says. Experts say to watch for these signs” (June 11, 2024)
- MedicalXpress.com “New study helps explain how elderly individuals react differently to COVID-19 than young people” (Jun 10, 2024)
- Forbes.com “How A New Covid-19 Antibody Could Contribute To Advanced Vaccine Development” (June 7, 2024)
- News Medical Life Sciences “Novel small molecule oral antiviral could be a game-changer in the fight against future pandemics” (June 4, 2024)
- News Medical Life Sciences “IgG from long COVID patients induces specific symptoms in mice, confirming autoimmunity's role” (June 3, 2024)
- News Medical Life Sciences “Biological similarities found between chemo brain and brain fog after COVID-19” (May 22, 2024)
- News Medical Life Sciences “LVRNA009 mRNA vaccine shows long-term efficacy against SARS-CoV-2 variants” (May 20, 2024)
- Washington University School of Medicine in St. Louis “Repeat COVID-19 vaccinations elicit antibodies that neutralize variants, other viruses” (May 17, 2024)
- University of Missouri School of Medicine “COVID-19 Virus Could Damage Vision” (May 14, 2024)
- News Medical Life Sciences “Novel bispecific antibodies show promise against evolving SARS-CoV-2 variants” (May 9, 2024)
- University of Cambridge “New vaccine effective against coronaviruses that haven’t even emerged yet” (May 6, 2024)
- MedicalNewsToday “Common antibiotic Neosporin may shield against viral respiratory infections” (April 26, 2024)
- News Medical Life Sciences “Repurposed nasal antibiotic neomycin shows promise in preventing and treating respiratory viral infections” (April 24, 2024)
- U.S. News & World Report “Neosporin Ointment in the Nose Might Be Potent Antibiotic” (April 23, 2024)
- News Medical Life Sciences “Innovative peptide-based hydrogel therapy for virus prevention” (April 23, 2024)
- Yale School of Medicine News “A Better COVID Treatment for the Immunocompromised?” (April 23, 2024)
- YaleNews “Common antibiotic may be helpful in fighting respiratory viral infections” (April 22, 2024)
- Technology Networks “Building Better Antibodies and Curbing Autoimmune Diseases” (April 19, 2024)
- SciTechDaily “Groundbreaking Study Reveals Potential Treatment for COVID-19 Brain Fog” (April 3, 2024)
- National Institutes of Health (NIH) “How lung distress from SARS-CoV-2 can cause heart damage” (April 2, 2024)
- MedicalXpress “Researchers race to develop Paxlovid replacement” (March 28, 2024)
- Usc.edu “COVID-19 research: New details about potentially deadly inflammation revealed in USC study” (March 28, 2024)
- News Medical Life Sciences “Heart at risk from ARDS: Inflammatory responses fuel cardiovascular complications” (March 24, 2024)
- News Medical Life Sciences “Researchers identify mechanism behind COVID-19 related brain fog” (March 21, 2024)
- University of Illinois Today “Research offers hope for preventing post-COVID 'brain fog' by targeting brain's blood vessels” (March 21, 2024)
- UPI.com Health News “Study shows heart damage from COVID-19” (March 21, 2024)
- Healio.com “Virus that causes COVID-19 can damage heart even if heart tissue not directly affected” (March 20, 2024)
- National Institutes of Health (NIH) “Severe lung infection during COVID-19 can cause damage to the heart” (March 20, 2024)
- News Medical Life Sciences “SARS-CoV-2-associated ARDS can damage the heart without direct infection” (March 20, 2024)
- Fierce Biotech “New protease inhibitor outperforms Paxlovid in protecting lungs of mice with COVID” (March 14, 2024)
- News Medical Life Sciences “New drug candidate designed at the atomic level could help halt emerging SARS-CoV-2 variants” (March 14, 2024)
- Stanford News “Going atom-by-atom, Stanford researchers craft a new precision drug for fighting COVID-19” (March 13, 2024)
- News Medical Life Sciences “Metal organic frameworks enhance immune response in experimental vaccine” (March 6, 2024)
- News Medical Life Sciences “New class of antiviral drugs could shield against future viral outbreaks” (March 4, 2024)
- News Medical Life Sciences “Scientists uncover a new doorway for SARS-CoV-2 into human cells” February 27, 2024)
- News Medical Life Sciences “Gut microbial metabolite plays a role in exacerbating thrombosis” February 23, 2024)
- MedicalXpress “Mouse study shows long COVID-19 infection linked with tangled protein that causes Alzheimer's disease” (February 23, 2024)
- University of Alberta Folio “New class of antivirals works against broad range of RNA viruses including SARS-CoV-2: study” (February 22, 2024)
- SciTechDaily “The Invisible Defense: Gut Bacteria’s Surprising Role in Combating Flu and COVID-19” (February 12, 2024)
- News Medical Life Sciences “SARS-CoV-2 fragments found to mimic immune system peptides, fueling inflammation” (February 5, 2024)
- News Medical Life Sciences “New DNA-based vaccine can induce strong antibody response against SARS-CoV-2” (January 30, 2024)
- MIT News “DNA particles that mimic viruses hold promise as vaccines” (January 30, 2024)
- News Medical Life Sciences “Gut microbiome may hold key to fighting common respiratory viruses” (January 30, 2024)
- News Medical Life Sciences “Zombie viral fragments trigger inflammation to cause serious COVID-19 outcomes” (January 30, 2024)
- News Medical Life Sciences “How does the nasal cavity's immune system combat SARS-CoV-2?” (January 28, 2024)
- News Medical Life Sciences “Prior exposure to common cold coronaviruses can train T cells to fight SARS-CoV-2” (January 27, 2024)
- MedicalXpress “Common cold or COVID-19? Some T cells are ready to combat both” (January 26, 2024)
- Science.org “Why does COVID-19 make you sneeze?” (January 23, 2024)
- Phys.org “Scientists make COVID receptor protein in mouse cells” (January 22, 2024)
- News Medical Life Sciences “Scientists demonstrate way to produce SARS-CoV-2 receptor protein in mouse cells” (January 22, 2024)
- Dagens.com (AU) “Groundbreaking development in COVID19-research: Scientists make receptor protein in mouse cells” (January 22, 2024)
- Healthnews.com “Don't Panic Over Chinese Experiment Modifying Coronavirus, Scientists Say” (January 19, 2024)
- abc3340.com “China 'cloned' COVID-like virus to test on mice, acknowledges 'spillover' risk to humans” (January 17, 2024)
- Toronto Sun “Chinese scientists create mutant COVID strain that kills mice” (January 17, 2024)
- The Sun “Chinese scientists test chilling new Covid Franken-virus ‘with 100% kill rate’ in humanised mice” (January 17, 2024)
- News Medical Life Sciences “Study reveals intestinal helminth infection diminishes T cell response to COVID-19 mRNA vaccine” (January 17, 2024)
- News Medical Life Sciences “New vaccine turns preexisting flu immunity into COVID-19 weapon” (January 17, 2024)
- New York Post “Chinese lab crafts mutant COVID-19 strain with 100% kill rate in ‘humanized’ mice: ‘Surprisingly’ rapid death” (January 16, 2024)
- Cornell Chronicle “Mice without immune cells show no SARS-CoV-2 symptoms” (January 11, 2024)
- Karolinska Institutet News “Nasal spray with antibodies could prevent COVID-19” (January 10, 2024)
2023 News
- News Medical Life Sciences “New non-steroidal anti-inflammatory can inhibit the cytokine storm and preserve innate immunity” (December 28, 2023)
- News Medical Life Sciences “New dry powder aerosol COVID-19 vaccine shows promise against multiple virus strains” (December 15, 2023)
- News Medical Life Sciences “IFN-gamma identified as crucial for reducing pulmonary viral loads in COVID-19, new research shows” (December 14, 2023)
- News Medical Life Sciences “Evaluation of immunogenicity-induced DNA vaccines against different SARS-CoV-2 variants” (December 12, 2023)
- EurekAlert! “HKUMed reveals new strategy for updating vaccines against evolving COVID-19 variants” (December 10, 2023)
- News Medical Life Sciences “A step forward in vaccine technology: Exploring the effects of N1-methylpseudouridine in mRNA translation” (December 7, 2023)
- MedicalXpress “New 'dictionary' of immune responses reveals far more complexity in the immune system than previously thought” (December 7, 2023)
- News Medical Life Sciences “Novel mRNA vaccine GLB-COV2-043 shows high efficacy against COVID-19 variants in early trials” (December 5, 2023)
- BioWorld “GHRH-R antagonist attenuates pulmonary dysfunction, heart injury in COVID-19 mice” (November 27, 2023)
- University of Florida Health “Combination of two common compounds improves COVID survival in mice, UF researchers find” (November 22, 2023)
- University of Queensland News “Turning back the clock on brains aged by COVID-19” (November 22, 2023)
- News Medical Life Sciences “Researchers discover way to reverse brain aging caused by COVID-19” (November 22, 2023)
- ABC News Australia “University of Queensland trial on mice, tissue cells, a potential first step in treating COVID-19 brain fog” (November 21, 2023)
- News Medical Life Sciences “Senolytics show promise in combating brain aging and COVID-19 neuropathology” (November 15, 2023)
- National Public Radio (NPR) “Pain, fatigue, fuzzy thinking: How long COVID disrupts the brain” (November 13, 2023)
- Infectious Disease Special Edition (IDSE) “The Gut’s Lasting Impact on Severe COVID-19 Immune Response” (November 8, 2023)
- University of Wisconsin-Madison News “New study shows mRNA vaccine harnesses T-cell power to combat COVID-19 in lungs” (November 6, 2023)
- MedicalXpress “Researchers develop a nasal vaccine that prevents COVID-19 in preclinical studies” (November 6, 2023)
- European Animal Research Association “Modified mice have ‘human-like’ COVID-19 symptoms” (November 6, 2023)
- University of Maryland AGNR News “UMD Researchers Developed a Nasal Vaccine that Prevents COVID in Preclinical Studies” (November 6, 2023)
- News Medical Life Sciences “New nasal vaccine for COVID-19 shows promise in animal studies” (November 6, 2023)
- Inside Precision Medicine “First Human-Like COVID-19 Mouse Model Created” (November 6, 2023)
- LaboratoryEquipment.com “Humanized Mouse Model Survives COVID-19 like the Young” (November 3, 2023)
- News Medical Life Sciences “New gene editing method creates first mice with human-like COVID-19” (November 1, 2023)
- NYU Langone Health “First Mice Engineered to Survive COVID-19 Are Like Young, Healthy Humans” (November 1, 2023)
- InterestingEngineering.com “Scientists engineer first mice to tolerate COVID-19 like young humans” (November 1, 2023)
- SienceDaily “First mice engineered to survive COVID-19 like young, healthy humans” (November 1, 2023)
- Yale School of Medicine “Could a New Vaccine Head Off the Next Pandemic?” (October 25, 2023)
- News Medical Life Sciences “Study sheds light on role of gut fungi in severe COVID-19 and long COVID” (October 24, 2023)
- News Medical Life Sciences “Intranasal vaccination: A potent one-time solution for comprehensive COVID-19 immunity” (October 24, 2023)
- National Public Radio “Long COVID brain fog may originate in a surprising place, say scientists” (October 24, 2023)
- Nature News “Inflammation in severe COVID linked to bad fungal microbiome” (October 23, 2023)
- The Conversation “Could gut fungi be linked to severe COVID? What to make of new research findings” (October 23, 2023)
- National Public Radio “Does long COVID brain fog start in the gut?” (October 22, 2023)
- TheNewsMill.com “Vaccine that offers protection against three deadly coronavirus types has shown promise in mouse trials” (October 21, 2023)
- SciTechDaily “Triple Threat – Single Vaccine Protects Against Three Deadly Strains of Coronavirus” (October 21, 2023)
- The Times of India “Vaccine that offers protection against three deadly coronavirus types has shown promise in mouse trials” (October 21, 2023)
- News Medical Life Sciences “Low serotonin levels observed in long COVID and other viral infections” (October 20, 2023)
- News Medical Life Sciences “Pan-coronavirus vaccine shows success in mouse studies” (October 18, 2023)
- Smithsonian Magazine “Reduced Serotonin Levels Could Cause Long Covid Symptoms, Study Finds” (October 18, 2023)
- News Medical Life Sciences “Paxlovid treatment provides protection against COVID-19 for both mother and child” (October 16, 2023)
- News Medical Life Sciences “Next-gen intranasal vaccine takes on measles, mumps, and multiple COVID-19 variants in one shot” (October 8, 2023)
- Emerging and Pandemic Infections Consortium “University of Toronto researchers unveil new preclinical insights into why males are more likely to have severe COVID-19” (September 29, 2023)
- News Medical Life Sciences “Aerosolized ACE2 neutralizes COVID-19 variants in lab and mice tests” (September 28, 2023)
- News Medical Life Sciences “Zoonotic spillover safeguarding: computationally designed antigen targets range of coronaviruses” (September 27, 2023)
- The Times of India “Omicron subvariant BA.5 more virulent, study in mice finds” (September 27, 2023)
- Cornell Chronicle “Contagious omicron strain replicates early in infection” (September 25, 2023)
- News Medical Life Sciences “Study identifies a molecule that may be behind COVID-19 brain fog” (September 20, 2023)
- Mirage News “Tau Proteins Linked to COVID-19 Brain Fog” (September 19, 2023)
- News Medical Life Sciences “Nanoparticle gene delivery system shows promise for treating ARDS” (September 19, 2023)
- Newsweek.com “Was New COVID Vaccine Booster Tested on Only 8 Mice? What We Know” (September 13, 2023)
- Yale Daily News “Yale researchers develop nasal spray mRNA vaccine for COVID-19” (September 8, 2023)
- News Medical Life Sciences “Self-adjuvanting RNA vaccines boost immune response 10x more than existing vaccines” (September 8, 2023)
- MIT News “MIT engineers design more powerful RNA vaccines” (September 7, 2023)
- Reuters.com “Pfizer says updated COVID shot generated strong reaction vs new variant in mice” (September 6, 2023)
- News Medical Life Sciences “Novavax's updated XBB.1.5 vaccine shows promising cross-neutralizing antibodies against new COVID-19 variants” (September 5, 2023)
- Mirage News “Inhaled Molecules Block Covid in Mice” (August 31, 2023)
- Phys.org “Inhalable molecules neutralize SARS-CoV-2 in mice” (August 30, 2023)
- Mirage News “Texas Biomed, Scancell Collaborate on New COVID Vaccine Test” (August 29, 2023)
- MedicalXpress “New grasp of key COVID-19 protein may lead to a live-attenuated vaccine effective against more variants for longer” (August 28, 2023)
- Specialty Pharmacy Continuum “Severe COVID-19 May Lead to Long-Term Innate Immune System Changes” (August 23, 2023)
- National Institutes of Health (NIH) “Severe COVID-19 may lead to long-term innate immune system changes” (August 18, 2023)
- News Medical Life Sciences “Severe COVID-19 may cause long-term changes to innate immune system” (August 18, 2023)
- Healio.com “Moderna, Pfizer say updated COVID-19 vaccines protect against EG.5” (August 18, 2023)
- Reuters.com “Pfizer's updated COVID shot effective against 'Eris' variant in mice study” (August 17, 2023)
- News Medical Life Sciences “Study reveals the roles of a nucleic acid sensor for COVID-19 in pan-cancer” (August 17, 2023)
- Genetic Engineering & Biotechnology News “Inhalable Polymer-Based Nanoparticles Deliver COVID-19 Vaccines to Mice” (August 16, 2023)
- News Medical Life Sciences “Genetically diverse mice reveal key differences in innate immune responses to SARS-CoV-2” (August 11, 2023)
- News Medical Life Sciences “Adjuvanted intranasal vaccine shows promise for long-lasting immunity to COVID-19” (August 7, 2023)
- Deccan Herald “Vaccine 'accessory' found to stop Covid infection in the nasal tract” (August 5, 2023)
- Mirage News “Intranasal COVID-19 Vaccine Shields Mice of All Ages” (August 5, 2023)
- News Medical Life Sciences “Intranasally administered SARS-CoV-2 RBD-based nanoparticle vaccine provides protection against lung pathology and viral load” (August 2, 2023)
- LabPulse.com “Viral vector-based decoy receptors protect mice against COVID-19 infection” (August 2, 2023)
- News Medical Life Sciences “Antiviral protein protects against COVID-19 in live mouse models” (August 1, 2023)
- UTSouthwestern.edu “Protein inhibits development of COVID-19 in live animals” (July 31, 2023)
- Agencia FAPESP “Compound reduced inflammation in COVID-19-infected mice without compromising immune response to virus” (July 26, 2023)
- News Medical Life Sciences “Brazilian researchers identify new way to stop excessive inflammation in COVID-19” (July 25, 2023)
- InvestorIntel “Zentek’s Breakthrough Aptamer Platform Shows Promise in Fighting COVID-19” (July 25, 2023)
- Pasadena Now “New Breakthrough Vaccine Technology Developed at Caltech” (July 25, 2023)
- MedicalXpress “New vaccine technology produces more antibodies against SARS-CoV-2 in mice” (July 25, 2023)
- Caltech “New Vaccine Technology Produces More Antibodies Against SARS-CoV-2 in Mice” (July 25, 2023)
- MedicalXpress “COVID-19 can cause inflammation that results in bone loss, higher fracture risk” (July 24, 2023)
- News Medical Life Sciences “High body temperature may boost gut microbiota to fight viral infections” (July 20, 2023)
- Health Feedback “Claim that a mouse study shows COVID-19 vaccine causes “turbo cancer” distorts study findings” (July 20, 2023)
- News Medical Life Sciences “SARS-CoV-2 spike protein's role in lung injury unraveled: promising new approach uncovered” (July 19, 2023)
- News Medical Life Sciences “Omicron subvariant BA.5 can cause more severe disease” (July 17, 2023)
- News Medical Life Sciences “Unveiling the key defender: PLSCR1 identified as a potent anti-SARS-CoV-2 factor in COVID-19 immunity” (July 14, 2023)
- News Medical Life Sciences “Novel approach: intranasal vaccination strategy targets Omicron COVID-19 variants” (July 14, 2023)
- News Medical Life Sciences “IL-9 identified as contributor to viral spread and airway inflammation in COVID-19” (July 13, 2023)
- News Medical Life Sciences “mAb-based bELISA developed to detect SARS-CoV-2 antibodies in a broad spectrum of animal species” (July 11, 2023)
- News Medical Life Sciences “Researchers identify glycolipid that blocks infection with SARS-CoV-2 and RSV” (July 11, 2023)
- MedicalXpress “New anticoagulants may help treat sepsis and COVID-19” (June 21, 2023)
- News Medical Life Sciences “Apple-shaped obesity associated with greater inflammation and mortality in COVID-19 patients” (June 20, 2023)
- News Medical Life Sciences “Trained immunity: its role in COVID-19 and potential in preparing for future infectious outbreaks” (June 16, 2023)
- National Institutes of Health (NIH) “Designing a SARS-CoV-2 decoy” (June 13, 2023)
- News Medical Life Sciences “Mechanistic insights into how the SARS-CoV-2 virus affects the nervous system, alters its function, and causes neuropathology” (June 9, 2023)
- Yahoo!News “Fused brain cells, neuron damage may explain long COVID” (June 8, 2023)
- MedicalXpress “In mice, naturally derived nanocarriers reduce lung inflammation, tissue damage” (June 6, 2023)
- MedicalXpress “New monoclonal antibodies targeting ACE2 receptor could treat the next waves of SARS-CoV-2” (June 5, 2023)
- News Medical Life Sciences “A SARS-CoV-2 spike-targeting bispecific T-cell engager strategy for controlling SARS-CoV-2 infection” (June 5, 2023)
- News Medical Life Sciences “Lymphoid depletion associated with suppressed APC function characterizes the lethality of COVID-19 in mice” (June 2, 2023)
- Pharmacy Times “COVID-19 Infection Could Be Detected in Lungs, Heart, Causing Inflammatory Damage” (June 2, 2023)
- Inside Precision Medicine “A Molecular Decoy Provides 100% Protection against COVID-19 in Lab Studies” (June 1, 2023)
- MedicalXpress “Study in SARS-CoV2 infected mice may lay the groundwork for novel therapies to reduce the severity of COVID-19” (June 1, 2023)
- News Medical Life Sciences “Experimental decoy provides long-term protection from SARS-Cov-2 infection” (May 30, 2023)
- News Medical Life Sciences “Novel technology enhances potency and breadth of vaccine-induced responses through antigen presentation” (May 30, 2023)
- NYU Langone Health NewsHub “Experimental Decoy Protects Against SARS-CoV-2 Infection” (May 30, 2023)
- MedicalXpress “T helper cells determine the course of disease in viral infections such as COVID-19: Study” (May 29, 2023)
- News Medical Life Sciences “T-cell-inducing mRNA COVID-19 vaccine improves effectiveness” (May 25, 2023)
- The Weather Channel “Indian Researchers Create Antiviral Drugs that Could Stop COVID-19 and Influenza – Including New Strains!” (May 25, 2023)
- News Medical Life Sciences “COVID-19 'bites the apple': Abdominal obesity ignites cytokine storm” (May 24, 2023)
- News Medical Life Sciences “Synthetic delivery vector STxB induces mucosal immunity against viral antigens” (May 21, 2023)
- News Medical Life Sciences “Novel antibodies target human receptors to neutralize SARS-CoV-2 variants and future sarbecoviruses” (May 17, 2023)
- News Medical Life Sciences “Study identifies extremely potent monoclonal antibodies that neutralized multiple sarbecoviruses” (May 12, 2023)
- MedicalXpress “Abdominal aortic aneurysm: New treatment may reduce size; COVID infection may speed growth” (May 11, 2023)
- News Medical Life Sciences “COVID-19 infection may promote aortic aneurysms and new treatment may slow its growth” (May 10, 2023)
- Northwestern University Feinberg News Center “Bioengineered Protein May Prevent COVID Infections and Improve Survival” (May 9, 2023)
- Nature News “Remarkable AI tool designs mRNA vaccines that are more potent and stable” (May 2, 2023)
- SciTechDaily “MIT’s Vaccine Printer: The Game-Changer in Vaccine Distribution” (May 2, 2023)
- FierceBiotech “New type of RNA degrader lowers COVID-19 viral load in mice, opening path to new drug class” (April 28, 2023)
- News Medical Life Sciences “Neurological phenotypes induced by SARS-CoV-2 spike protein in neurons” (April 27, 2023)
- News Medical Life Sciences “Research uncovers antibodies that are still effective against new variants of SARS-CoV-2” (April 26, 2023)
- News Medical Life Sciences “Print your own vaccine: automatic printing of microneedle patch COVID-19 mRNA vaccines” (April 26, 2023)
- MedicalXpress “Even as SARS-CoV-2 mutates, some human antibodies fight back” (April 25, 2023)
- News Medical Life Sciences “A mobile vaccine printer could enable rapid vaccination of large numbers of people” (April 24, 2023)
- MedicalXpress “Vaccine printer could help vaccines reach more people” (April 24, 2023)
- MedicalXpress “Research unveils paths to stopping cytokine storms in COVID-19” (April 21, 2023)
- The Weather Channel “Scientists Develop New T-Cell COVID Vaccine That Could Provide Sustained Immunity Against Future Variants!” (April 21, 2023)
- News Medical Life Sciences “Protective mucosal and systemic immunity provided by a single-dose novel live-attenuated intranasal SARS-CoV-2 vaccine candidate” (April 20, 2023)
- News Medical Life Sciences “New DCFHP-alum COVID-19 vaccine candidate shows durable, broad-spectrum protection in non-human primates” (April 18, 2023)
- News Medical Life Sciences “Cocktail of IgG3 antibodies could have a potent clinical effect against SARS-CoV-2” (April 18, 2023)
- SciTechDaily “New AI-Generated T-Cell Vaccine Showcases Long-Lasting Immunity Against COVID-19” (April 18, 2023)
- The American Bazaar “AI generated Covid-19 vaccine may provide long-lasting immunity” (April 17, 2023)
- The New Indian Express “Researchers claim AI-designed T-cell vaccine could offer protection against severe Covid-19” (April 15, 2023)
- News Medical Life Sciences “How SARS-CoV-2 Omicron subvariants have evolved to evade host T-cell immunity” (April 15, 2023)
- News Medical Life Sciences “Study develops a novel intranasal influenza virus-vectored vaccine for SARS-CoV-2” (April 14, 2023)
- News Medical Life Sciences “AI-designed T-cell vaccine extremely effective at preventing severe COVID-19 in mice” (April 13, 2023)
- News Medical Life Sciences “The identification of vaccinee-derived antibodies with broad-spectrum Omicron neutralization activity” (April 12, 2023)
- News Medical Life Sciences “Study highlights the potential long-term neurological effects post-COVID-19” (April 10, 2023)
- News Medical Life Sciences “Omicron BA.5 variant demonstrates increased neuroinvasiveness and pathogenicity in mice” (April 5, 2023)
- RepublicWorld.com “Spike Protein Of SARS-CoV-2 Implicated In Memory Impairment Post-Covid” (April 4, 2023)
- MedicalXpress “Spike protein implicated in post-COVID-19 memory loss” (April 3, 2023)
- News Medical Life Sciences “Spike protein could be responsible for memory loss in post-COVID-19 syndrome” (April 3, 2023)
- Contagion Live “Nasal Spray Blocks SARS-CoV-2 Variants” (April 3, 2023)
- News Medical Life Sciences “Red blood cell hitch-hiking facilitates SARS-CoV-2 multi-organ spread” (April 3, 2023)
- News Medical Life Sciences “Study identifies ultra-broad SARS-CoV-2 neutralizing antibodies that target various spike epitopes” (April 3, 2023)
- News Medical Life Sciences “What is the effect of prior BCG vaccination on the immunogenicity and efficacy of subsequent COVID-19 vaccination?” (March 28, 2023)
- Mirage News “Drug Targets Found for Key Pathophysiologies in J. Pharm. Analysis” (March 23, 2023)
- The Standard “Scientists find therapeutic target for Covid” (March 21, 2023)
- News Medical Life Sciences “Next-gen Mpro inhibitor: Promising new drug candidate against Omicron and other SARS-CoV-2 variants” (March 21, 2023)
- MedicalXpress “Runaway immune reactions can cause long COVID breathing problems” (March 20, 2023)
- News Medical Life Sciences “Does vitamin D play an antiviral role against SARS-CoV-2?” (March 17, 2023)
- News Medical Life Sciences “Researchers identify a potential treatment to prevent severe COVID-19 in high-risk patients” (March 15, 2023)
- MIT News “Creating a versatile vaccine to take on Covid-19 in its many guises” (March 9, 2023)
- National Institutes of Health “Inhalable hydrogel protects lungs from SARS-CoV-2” (March 7, 2023)
- News Medical Life Sciences “Antibody levels from prime COVID-19 mRNA vaccine influences the efficacy of booster doses” (March 6, 2023)
- MedicalXpress “New COVID-19 booster vaccine offers high level of protection in mice” (March 3, 2023)
- News Medical Life Sciences “Study identifies the essential genetic and immunologic perturbations occurring in patients with long COVID lung fibrosis” (March 3, 2023)
- Shanghai Daily “NZ-made COVID-19 booster vaccine offers full protection in preclinical study” (March 3, 2023)
- ET Health World “Human antibodies found that can block multiple coronaviruses: Study” (March 1, 2023)
- NewsDrum “New, naturally-derived, nanovaccine against COVID-19 shows success in mice trials: Study” (February 28, 2023)
- MedicalXpress “A possible way to prevent or treat lung damage associated with long COVID” (February 28, 2023)
- Business Wire “Xlear Provides New Data to the Dept. Of Justice; Study Showing Nasal Spray Reduces COVID-19 Infections by 62% Included” (February 27, 2023)
- University of Washington Newsroom “Inflammation is culprit behind long COVID, study suggests” (February 24, 2023)
- SciTechDaily “New artificial model validates antibodies ability to reach the brain” (February 24, 2023)
- News Medical Life Sciences “RBD-NTD-subunit protein vaccine provides a promising booster vaccination strategy capable of protecting against known SARS-CoV-2 variants” (February 22, 2023)
- News Medical Life Sciences “Researchers report the circulation of a novel MERS-like coronavirus in Malayan pangolins” (February 21, 2023)
- SciTechDaily “Outsmarting COVID-19: Weaponizing the Spike Protein Against Itself To Prevent Infection” (February 21, 2023)
- Earth.com “COVID-19 patients experience changes in heart tissue” (February 20, 2023)
- NBC News “Covid can cause heart problems. Here's how the virus may do its damage” (February 20, 2023)
- Northwestern Now “Your first COVID-19 vaccination ‘hurts’ subsequent boosters” (February 20, 2023)
- Fortune.com “COVID increases your risk for heart failure and stroke for at least a year, experts say. Here are 8 ways to protect your health” (February 18, 2023)
- Mirage News “Weaponizing Spike Protein to Block Covid Infection” (February 18, 2023)
- ABP Live “Next-Gen Covid-19 Vaccine Developed by IIT Delhi Using Immune Cells Can Reduce Blood Clotting: Study” (February 16, 2023)
- The Weather Channel “Inhalable Powder Could Protect Against Flu, COVID” (February 15, 2023)
- News Medical Life Sciences “Researchers report a physical barrier against SARS-CoV-2 infection based on an inhalable bioadhesive hydrogel” (February 13, 2023)
- Yahoo!Finance “Tonix Pharmaceuticals Announces Exclusive License of Potential Therapeutic or Preventative Fully Human and Murine Anti-SARS-CoV-2 Monoclonal Antibodies” (February 13, 2023)
- News Medical Life Sciences “Study suggests SARS-CoV-2 is likely to only infect placental mammals” (February 9, 2023)
- News Medical Life Sciences “Novel COVID-19 protein component vaccine elicits durable immune response in rodents” (February 9, 2023)
- MedicalXpress “Researcher might have found key to understanding why COVID-19 kills more men than women” (February 2, 2023)
- Genetic Library Project “It’s not just humans that get COVID — other animals are susceptible too” (February 1, 2023)
- GlobeNewswire “EnGeneIC publishes the COVID-EDV vaccine’s novel mechanism of action in a leading Immunology journal” (January 31, 2023)
- Genetic Engineering & Biotechnology News “Broad Range Antibodies Neutralize All SARS-CoV-2 Variants and Other Coronaviruses” (January 30, 2023)
- News Medical Life Sciences “Repression of endothelial TLR3 is a potential mechanism of SARS-CoV-2 infection-associated lung vascular remodeling” (January 30, 2023)
- MedicalXpress “Evolutionary history of SARS-CoV-2 leads to a universal vaccine already being tested in animal models” (January 30, 2023)
- Contagion Live “Study Identifies Links Between Gut Dysbiosis and COVID-19” (January 26, 2023)
- NIH COVID-19 Research “How COVID-19 Changes the Gut Microbiome” (January 25, 2023)
- Yahoo!Finance “Tonix CEO Calls for New Class of Covid-19 Pre-Exposure and Therapeutic Antibodies for High-Risk Populations” (January 24, 2023)
- News Medical Life Sciences “Senolytics could be a beneficial therapeutic for COVID neuropathology” (January 22, 2023)
- News Medical Life Sciences “Phase I trial results from AdaptVac's COVID capsid virus-like particle vaccine” (January 22, 2023)
- Miami Herald “No-needle COVID vaccine may protect you better, researchers say. How does it work?” (January 20, 2023)
- MedicalXpress “Antiviral compound could be broadly efficient in the treatment of SARS-CoV-2” (January 20, 2023)
- Mirage News “Antiviral Compound Shown Effective Against Covid” (January 20, 2023)
- Futurity “B cell ‘boot camp’ insights could inform future vaccines” (January 19, 2023)
- News Medical Life Sciences “Upregulation of Robo4 expression reduces mortality from severe infection” (January 18, 2023)
- The Washington Post “Lab-leak fears are putting virologists under scrutiny” (January 18, 2023)
- News Medical Life Sciences “What is the effectiveness of a multivalent exosome-based COVID-19 vaccine?” (January 16, 2023)
- News Medical Life Sciences “Researchers report that vectored expression of a high-affinity ACE2 microbody protein establishes a high degree of protection from SARS-CoV-2” (January 16, 2023)
- ScienceDaily “How sex differences influence lung injury in mice” (January 12, 2023)
- News Medical Life Sciences “CNB-CSIC vaccine fully protects against SARS-CoV-2 infection of the brain” (January 12, 2023)
- News Medical Life Sciences “Study on the ecology of viruses in urban rodents with special emphasis on SARS-CoV-2” (January 12, 2023)
- Boston University “NEIDL Researchers Discover New SARS-CoV-2 Weak Spot—Which Could Inspire Improved Vaccines” (January 11, 2023)
- MirageNews.com “CSIC Vaccine Prevents COVID-19 Infection, Brain Damage” (January 10, 2023)
- News Medical Life Sciences “Researchers demonstrate how CNB-CSIC vaccine fully protects against SARS-CoV-2 infection of the brain” (January 9, 2023)
- News Medical Life Sciences “COVID-19 vaccine potency and breadth improved by nanoparticle-conjugated adjuvants” (January 8, 2023)
- Global News “A mucosal vaccine could be a COVID-19 game-changer. So why doesn’t Canada have one?” (January 7, 2023)
- News Medical Life Sciences “Pan-vaccine antigen strategy confers protection against cross-clade SARS-CoV-2 variants, including vaccine-resistant Omicron variants” (January 6, 2023)
- Drug Target Review “The spike of SARS-CoV-2 promotes metabolic rewiring in hepatocytes” (January 4, 2023)
- The Conversation “COVID and your gut: how a healthy microbiome can reduce the severity of infection – and vice versa” (December 29, 2022)
- Yahoo!Finance “Oragenics Reports Favorable Toxicology Results for its COVID-19 Intranasal Vaccine Candidate (December 22, 2022)
- News Medical Life Sciences “Researchers generate a remodeled live-attenuated measles vaccine capable of driving nAb responses against SARS-CoV-2 spike protein” (December 20, 2022)
2022 News
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News Medical Life Sciences “Study demonstrates robust antibody response elicited by trivalent protein subunit vaccine against SARS-CoV-2” (December 19, 2022)
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SciTechDaily “A New Drug Could Fight Both COVID and Cancer” (December 18, 2022)
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ABP Live “Mucosal DNA Vaccine Found Effective In Stopping COVID-19 In Its Tracks: Study” (December 17, 2022)
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EurekAlert! “COVID-19: a respiratory vaccine effective in mice” (December 16, 2022)
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News Medical Life Sciences “Research reveals that a viral toxin may contribute to the severity of COVID-19” (December 14, 2022)
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The Bakersfield Californian “Dyadic's DYAI-100 COVID-19 Vaccine Study Publishedin a Leading Peer-Reviewed Scientific Article” (December 14, 2022)
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News Medical Life Sciences “Obesity and type 2 diabetes impair mRNA COVID vaccine efficacy in mouse model” (December 13, 2022)
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News Medical Life Sciences “Intranasal recombinant MVA-based vaccines effective against SARS-CoV-2 variants in mice” (December 11, 2022)
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ASBMB Today “What next-gen Covid-19 vaccines might look like” (December 10, 2022)
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UC Berkeley News “How a viral toxin may exacerbate severe COVID-19” (December 9, 2022)
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ScienceDaily “New findings on how to avert excessive weight loss from COVID-19” (December 8, 2022)
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News Medical Life Sciences “The requirement for Fc effector functions to protect against SARS-CoV-2 infection” (December 1, 2022)
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Genetic Engineering & Biotechnology News “SARS-CoV-2 May Be Thwarted by Nasally Administered DARPins” (November 29, 2022)
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News Medical Life Sciences “Researchers uncover a link between D-amino acids and severe viral infection” (November 28, 20222)
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National Institutes of Health “COVID-19 disrupts gut microbiome” (November 22, 2022)
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News Medical Life Sciences “Novel nasal vaccine approach induces potent lung immunity and protection against SARS-CoV-2” (November 16, 2022)
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TheScientist “Scientists ID Heart-Damaging SARS-CoV-2 Protein” (November 16, 2022)
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News Medical Life Sciences “The impact of lung remodeling from prior helminth infection on SARS-CoV-2 disease pathogenesis” (November 15, 2022)
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News Medical Life Sciences “Novel drug could help to fight both COVID-19 and cancer” (November 14, 2022)
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Genetic Engineering & Biotechnology News “COVID-19 and Cancer May Have Common Drug Target in GRP78” (November 14, 2022)
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News Medical Life Sciences “How mRNA vaccines work without an added adjuvant” (November 13, 2022)
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Yale Daily News “New Yale study finds promising results with nasal COVID-19 vaccine” (November 10, 2022)
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News Medical Life Sciences “SARS-CoV-2 activates NLRP3 inflammasome” (November 7, 2022)
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News Medical Life Sciences “An innovative nasal vaccine strategy to combat COVID” (October 31, 2022)
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News Medical Life Sciences “The impact of seasonal coronavirus immunity on susceptibility to SARS-CoV-2 infection and COVID-19 vaccination” (October 28, 2022)
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EurekAlert! “Cancer therapy shows potential to treat severe COVID-19 in pre-clinical trials” (October 27, 2022)
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Wired.com “Where Did Omicron Come From? Maybe Its First Host Was Mice” (October 27, 2022)
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The New York Times “Lab Manipulations of Covid Virus Fall Under Murky Government Rules” (October 22, 2022)
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FactCheck.org “Social Media Claims Misrepresent Boston U. Study of What Causes Severity of COVID-19 Strains” (October 21, 2022)
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PolitiFact “Claim that Boston University created COVID-19 strain with an 80% kill rate omits important details” (October 20, 2022)
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News Medical Life Sciences “Immune-suppressing drug reverses symptoms of delirium in mice” (October 19, 2022)
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Vox.com “Why do labs keep making dangerous viruses?” (October 19, 2022)
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WVUToday “Obesity and biological sex may make individuals more vulnerable to COVID-19, WVU study suggests” (October 18, 2022)
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1News “Scientists make new Covid variant with 80% kill rate in mice” (October 18, 2022)
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Oregon State University Newsroom “Nanotechnology, messenger RNA combined in possible new ‘universal’ COVID-19 treatment” (October 18, 2022)
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STAT News “Boston University researchers’ testing of lab-made version of Covid virus draws government scrutiny” (October 17, 2022)
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Boston University “NEIDL Researchers Refute UK Article about COVID Strain” (October 17, 2022)
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abpLIVE.com “What Makes Covid-19 Severe? Study Uncovers Role of Virus Proteins Other Than Spike” (October 10, 2022)
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News Medical Life Sciences “Neonatal mice-based model established that allows for the transmission of clinical SARS-CoV-2 isolates” (October 7, 2022)
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University of Maryland School of Medicine News “Other SARS-CoV-2 Proteins are Important for Disease Severity, Aside from the Spike” (October 7, 2022)
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EurekAlert! “New type of RNA discovered that inhibits a broad range of viral infection” (October 5, 2022)
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News Medical Life Sciences “Omicron reduces host antibody response by lower B-cell antigenicity” (October 4, 2022)
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News Medical Life Sciences “Common germline variants of APOE contribute to differential COVID-19 outcomes” (September 26, 2022)
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News Medical Life Sciences “Prophylactic administration of SARS-CoV-2 specific immunoglobulin Y generated in chicken eggs displays protective effects in infected mice” (September 21, 2022)
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News Medical Life Sciences “Molecular engineered low-cost highly effective RBD-based COVID vaccine” (September 19, 2022)
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News Medical Life Sciences “An improved COVID-19 vaccine shows promise against Omicron in experimental models” (September 18, 2022)
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News Medical Life Sciences “Customized bivalent mRNA COVID boosters protect against BA.5 Omicron variant” (September 14, 2022)
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News Medical Life Sciences “Intranasal administration of liposomes displaying SARS-CoV-2 antigen induces mucosal immunity” (September 14, 2022)
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News Medical Life Sciences “What is the impact of COVID-19 treatments targeting intracellular Neu1?” (September 14, 2022)
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News Medical Life Sciences “Parenteral-prime mucosal boost an effective strategy to protect against SARS-CoV-2” (September 14, 2022)
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The Boston Globe “Boston Children’s Hospital researchers find antibody that neutralizes all major COVID variants in tests on mice” (September 13, 2022)
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Freethink.com “Newly discovered antibody neutralizes all variants of the coronavirus” (September 13, 2022)
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Forbes “Have The New Bivalent Covid-19 Vaccine Boosters Been Tested On Humans?” (September 12, 2022)
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Live Science “Should you get the new COVID-19 booster shot? Here's everything you need to know” (September 12, 2022)
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The Atlantic “One of Long COVID’s Worst Symptoms Is Also Its Most Misunderstood” (September 12, 2022)
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DW.com “Scientists identify a single antibody that may fight all COVID strains” (September 8, 2022)
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Mashable.com “Scientists claim to have found new antibody that destroys all forms of COVID-19” (September 8, 2022)
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Prevention.com “Scientists Discovered an Antibody That Can Take Out All COVID-19 Variants” (September 6, 2022)
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Healthline.com “Q&A: What You Need to Know About the New COVID-19 Omicron-Specific Vaccine Boosters” (September 6, 2022)
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MIT Technology Review “This nanoparticle could be the key to a universal covid vaccine” (September 5, 2022)
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University of Colorado Anschutz Newsroom “First Variant-Specific COVID-19 Vaccine Approved Targeting BA.4/BA.5” (September 5, 2022)
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Infection Control Today “The Autumn COVID-19 Booster Is Here: Is it Safe and Effective?” (September 2, 2022)
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Kera News “FDA expected to authorize new omicron-specific COVID boosters this week” (August 30, 2022)
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The Hindu “Artificial protein shell to combat COVID-19” (August 30, 2022)
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The Weather Channel “New Generation COVID-19 Vaccine Shows Promising Results Against Severe Infection from the Beta Variant of SARS-Cov2” (August 26, 2022)
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News Medical Life Sciences “Susceptibility of deer mice and California mice to COVID-19” (August 25, 2022)
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Drug Target Review “New generation of COVID-19 vaccines show promising results” (August 25, 2022)
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News@Northeastern “Benefits of new COVID-19 booster targeting variants outweigh any potential risks, experts say” (August 24, 2022)
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Deseret News “Why mouse data may determine the next round of COVID-19 booster shots” (August 23, 2022)
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National Public Radio (NPR) “What's behind the FDA's controversial strategy for evaluating new COVID boosters” (August 18, 2022)
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Weill Cornell Medicine Newsroom “Preclinical Study Suggests Gut Bacteria May Influence Viral Entry, Immune Response and Coagulation in COVID-19” (August 17, 2022)
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National Institutes of Health News “Fighting current and future coronaviruses with a single vaccine” (August 16, 2022)
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Harvard Medical School News & Research “One for All? New antibody neutralizes all known SARS-CoV-2 variants in lab tests” (August 15, 2022)
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News Medical Life Sciences “Gut microbiota-derived metabolites offer protection against SARS-CoV-2” (August 5, 2022)
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News Medical Life Sciences “mRNA vaccines induce faster antibody response against infectious diseases” (August 2, 2022)
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Medical News Today “Scientists compare skin patch vs. needle vaccine against SARS-CoV-2 variants” (August 1, 2022)
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Medical News Today “How does COVID-19 affect the heart? New clues arise” (August 1, 2022)
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ScienceDaily “COVID vaccine patch fights variants better than needles, study in mice shows” (July 28, 2022)
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CTInsider.com “Yale vaccine against Omicron shows flexibility of mRNA technology” (July 28, 2022)
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News Medical Life Sciences “Novel compound inhibits SARS-CoV-2 replication by binding a genome target” (July 27, 2022)
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The News & Observer “Duke researchers edit genes to prevent, treat COVID-19 in the lab. Will it work in people? (July 26, 2022)
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News Medical Life Sciences “Nasal spray highly effective against HIV and SARS-CoV-2 in animal models” (July 26, 2022)
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Forbes “Progress In The Search For Broadly Neutralizing Monoclonal Antibodies III” (July 26, 2022)
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Wired.com “These Vaccines Will Take Aim at Covid—and Its Entire SARS Lineage” (July 26, 2022)
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News Medical Life Sciences “Scientists identify papain-like protease inhibitor against COVID-19” (July 25, 2022)
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News Medical Life Sciences “A VSV-based COVID vaccine effective against SARS-CoV-2 variants” (July 25, 2022)
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News Medical Life Sciences “SARS-CoV-2 spike protein can lead to heart muscle injury through the inflammatory process” (July 25, 2022)
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ScienceDaily “Coronavirus spike protein activated natural immune response, damaged heart muscle cells, study finds” (July 25, 2022)
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The Week “Nasal sprays will be essential to tackle Covid-19 variants, study says” (July 23, 2022)
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CTV News “With a sniff or a swallow, new vaccines aim to put the brakes on COVID-19 spread” (July 23, 2022)
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Business Standard “Nasal sprays will be essential to tackle emerging Covid-19 variants: Study” (July 22, 2022)
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Drug Target Review “Scientists discover an antibody that potentially acts as a therapy against SARS-CoV-2” (July 22, 2022)
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EurekAlert! “A novel COVID-19 vaccine using modified bacterial DNA” (July 21, 2022)
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ScienceDaily “A novel COVID-19 vaccine using modified bacterial DNA” (July 21, 2022)
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UAB News “Demonstration of a potent, universal coronavirus monoclonal antibody therapy for all COVID-19 variants” (July 21, 2022)
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EurekAlert! “Demonstration of a potent, universal coronavirus monoclonal antibody therapy for all COVID-19 variants” (July 21, 2022)
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NBC29.com “UVA researchers: Nasal sprays important in fighting COVID-19 variants” (July 21, 2022)
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Firstpost.com “Novel COVID-19 vaccine offers superior protection against Omicron variants” (July 20, 2022)
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News Medical Life Sciences “The clinical, epidemiological, and evolutionary consequences of a potential SARS-CoV-2-related bat virus spillover into humans” (July 20, 2022)
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Pharmaceutical-Technology.com ”Gladstone and UCSF scientists discover BET protein role in Covid-19” (July 20, 2022)
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Yale News “Yale-developed vaccine offers superior protection against Omicron variants” (July 19, 2022)
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EurekAlert! “BETting on COVID-19: Study probes role of BET proteins in coronavirus infection” (July 19, 2022)
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NBC News “Nasal vaccines may stop Covid infections. Will we get them soon?” (July 19, 2022)
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EurekAlert! “Nasal sprays will be essential to thwart variants, UVA collaborative research confirms” (July 19, 2022)
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News Medical Life Sciences “Scientists evaluate immunostimulatory glycolipid against SARS-CoV-2 infection” (July 18, 2022)
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News Medical Life Sciences “Novel nanoligomer approach to treat severe COVID-19” (July 17, 2022)
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News Medical Life Sciences “The potential of circular RNA COVID-19 vaccines” (July 17, 2022)
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NeurologyAdvisor.com “Mild Respiratory COVID-19 Can Cause Neural Cell and Myelin Dysregulation” (July 14, 2022)
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MedicalNewsToday.com “Nanoparticle-based vaccine protects against COVID-19 variants, similar viruses” (July 12, 2022)
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News Medical Life Sciences “Experimental model reveals possible causes and treatments for long-COVID” (July 11, 2022)
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News Medical Life Sciences “Characterization of longer-term effects on behavior and brain inflammation following recovery from mild COVID-19” (July 8, 2022)
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News Medical Life Sciences “Nanoparticle vaccine could protect against animal viruses including future SARS-CoV-2 variants” (July 8, 2022)
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WebMD.com “Study Finds Possible Causes of, and Treatments for, Long COVID” (July 7, 2022)
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News Medical Life Sciences “Vitamin D protects against H1N1 and SARS-CoV-2 infection in mice” (July 5, 2022)
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Caltech.com News “Nanoparticle Vaccine Protects Against a Spectrum of COVID-19-causing Variants and Related Viruses” (July 5, 2022)
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ScienceDaily “Inhalable COVID-19 vaccine shows promise in rodent model” (July 5, 2022)
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Wired.com “The Secrets of Covid ‘Brain Fog’ Are Starting to Lift” (July 1, 2022)
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ScienceDaily “COVID-19 Omicron variant leads to less severe disease in mice, study finds” (June 27, 2022)
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Economic Times Healthorld.com “Covid infection may increase risk of Parkinson's, mice study suggests” (June 20, 2022)
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News Medical Life Sciences “GPR183 gene a novel drug target for severe COVID-19” (June 17, 2022)
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News Medical Life Sciences “Effectiveness of a hybrid vaccine against COVID-19 and influenza” (June 16, 2022)
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NIH Covid-19 Research “Antiviral Nasal Spray Shows Promise Fighting COVID-19” (June 16, 2022)
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News Medical Life Sciences “Fc-effector functions for selecting COVID-19 convalescent plasma” (June 15, 2022)
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News Medical Life Sciences “Even mild respiratory COVID can affect the brain” (June 14, 2022)
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Infectious Disease Special Edition “The Intersection of SARS-CoV-2 With TB: It's Complicated” (June 13, 2022)
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News Medical Life Sciences “Animal study suggests intranasal COVID vaccine delivery more efficient than intramuscular” (June 12, 2022)
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Outsourcing-Pharma.com “Envigo is addressing the need for models that mimic the long-term effects of COVID-19” (June 7, 2022)
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National Institutes of Health (NIH) News “T cells protect against COVID-19 in absence of antibody response” (June 7, 2022)
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News Medical Life Sciences “The effects of accessory protein mutations and other non-spike mutations on SARS-CoV-2 pathogenesis” (June 2, 2022)
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The Week “New strategy may reduce fatigue after Covid vaccination: Study” (June 2, 2022)
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News Medical Life Sciences “Inhibiting immune response-related enzyme holds promise in preventing or treating severe COVID-19” (June 1, 2022)
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Ohio State News “Blocking enzyme could hold the key to preventing, treating severe COVID-19” (June 1, 2022)
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The Economic Times “Acute stress may make it hard to fight against COVID-19” (May 31, 2022)
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EurekAlert! “New study points to potential strategy to reduce fatigue after COVID-19 vaccination” (May 31, 2022)
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News Medical Life Sciences “Researchers identify molecular characteristics linked to increased likelihood of post-vaccination fatigue” (May 31, 2022)
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EurekAlert! “Acute stress may be detrimental to fighting off COVID-19 and influenza” (May 30, 2022)
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News Medical Life Sciences “Researchers identify a human monoclonal antibody that could broadly neutralize several variants of SARS-CoV-2, SARS-CoV, and other coronaviruses” (May 30, 2022)
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Medical News Today “Parkinson’s: SARS-CoV-2 infection raises risk in mice” (May 26, 2022)
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Parkinson’s News Today “In Mice, COVID-19 Leaves Nerve Cells Vulnerable to Further Injury” (May 25, 2022)
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Medical News Today “COVID-19: Repurposed antibiotic shows promise in mouse model” (May 24, 2022)
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Yale News “COVID vaccines do not impact fertility or pregnancy outcomes, study shows” (May 24, 2022)
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News Medical Life Sciences “New study counters claims that COVID-19 vaccines reduce fertility and affect fetal growth” (May 24, 2022)
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Outlook India “Covid-19 May Increase Risk Of Parkinson’s Disease, Finds Study” (May 23, 2022)
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News Medical Life Sciences “Repurposed drug clofoctol blocks SARS-CoV-2 replication in mouse study” (May 23, 2022)
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News Medical Life Sciences “Natural immunity weak and short-lived in unvaccinated after Omicron infection” (May 20, 2022)
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EurekAlert! “Study in mice suggests that COVID-19 increases risk of developing Parkinson’s disease” (May 18, 2022)
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News Medical Life Sciences “Evaluating efficacy of SARS-CoV-2 antivirals in a mouse model” (May 18, 2022)
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MIT Technology Review “Anti-aging drugs are being tested as a way to treat covid” (May 17, 2022)
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China Global Television Network “China develops mosaic vaccine for protection against COVID-19 variants” (May 17, 2022)
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The Scientist “Diabetes Marker Linked to COVID-19 Severity in Mice” (May 16, 2022)
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University of Wisconsin-Madison News “Experimental COVID-19 vaccine provides mutation-resistant T cell protection in mice” (May 13, 2022)
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Xinhua “Study finds glucose-like metabolite effective against COVID-19” (May 12, 2022)
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National Institutes of Health News “Intranasal proteins could protect against COVID-19 variants” (May 10, 2022)
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News Medical Life Sciences “Needle- and adjuvant-free vaccination with non-infectious T4-COVID nanoparticles induces strong immunity in mice” (May 3, 2022)
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News Medical Life Sciences “Does re-freezing COVID-19 mRNA vaccines affect immunogenicity?” (April 27, 2022)
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News Medical Life Sciences “Researchers use mouse model to explore correlation of impaired interferon-mediated immune response with severe COVID-19” (April 26, 2022)
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News Medical Life Sciences “mRNA booster vaccination found to protect aged mice against the Omicron variant of SARS-CoV-2” (April 26, 2022)
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News Medical Life Sciences “A novel mouse model to test SARS-CoV-2 viral infection” (April 26, 2022)
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News Medical Life Sciences “Study demonstrates that a low-dose, bivalent, unmodified mRNA vaccine against SARS-CoV-2 is highly efficacious” (April 22, 2022)
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Yahoo!Finance “CureVac and GSK's Bivalent Second-Generation mRNA Vaccine Candidate Shown to be Highly Effective Against SARS-CoV-2 Variants in Preclinical Study” (April 21, 2022)
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News Medical Life Sciences “Intranasal nanoparticle STING agonist with immunoantiviral activity against SARS-CoV-2 variants” (April 21, 2022)
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News Medical Life Sciences “Study evaluates the ocular tropism and the possible ocular transmission of SARS-CoV-2 in animal models” (April 20, 2022)
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Drug Target Review “Blocking host proteins: an improved COVID-19 treatment approach?” (April 19, 2022)
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News Medical Life Sciences “SARS-CoV-2 infection patterns in olfactory epithelium” (April 18, 2022)
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Hindustan Times “India's ‘warm’ vaccine candidate effective against Delta, Omicron variants in mice: Study” (April 16, 2022)
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Northwestern Now “New COVID-19 nasal spray outperforms current antibody treatments in mice” (April 13, 2022)
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National Institutes of Health “Nasal antiviral blocks SARS-CoV-2 infection in mice” (April 12, 2022)
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KHQA “New UI study shows treatment prevents COVID-19 deaths on older mice” (April 8, 2022)
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ThePrint “Study on mice shows Covid virus leads to brain neuron death, higher anxiety, reduced cognition” (April 8, 2022)
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Healthline “In Early Testing, Nasal Spray Shows Signs It Can Fight COVID-19” (April 8, 2022)
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News Medical Life Sciences “Insights into the pathogenesis of the previous and circulating SARS-CoV-2 variants in mice” (April 7, 2022)
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YaleNews “Immune system culprit in severe COVID cases found” (April 6, 2022)
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News Medical Life Sciences “Self-assembling SARS-CoV-2 spike protein-directed nanoparticle vaccines” (April 6, 2022)
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Shanghai Daily “New candidate vaccines against COVID-19 variants designed: study” (April 6, 2022)
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European Pharmaceutical Review “Designed for success – new SNA vaccine proves highly effective in mice” (April 6, 2022)
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MedicalNewsToday “Long COVID pain explained: Gene signature may play a role” (April 4, 2022)
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News Medical Life Sciences “Messenger ribonucleic acid boosters shown to be effective against Omicron infections in mice” (March 31, 2022)
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University of Iowa Health Care News “Drug protects older mice from worst effects of COVID-19” (March 31, 2022)
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News Medical Life Sciences “ACE2 decoy receptor with robust neutralization against Omicron subvariants shows therapeutic potential” (March 30, 2022)
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Wion News “Anti-COVID-19 nasal spray works on mice, effective against Delta variant: Study” (March 30, 2022)
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News Medical Life Sciences “Divalent SARS-CoV-2 fusion vaccine found to be effective in mice” (March 30, 2022)
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News Medical Life Sciences “Newcastle disease virus-based trivalent vaccine found to be effective across SARS-CoV-2 variants in mice” (March 29, 2022)
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Genetic Engineering & Biotechnology News “Nasal Spray for Prevention/Early Treatment of COVID-19 Works in Mice” (March 28, 2022)
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University of British Columbia Science “New nasal spray treats Delta variant infection in mice, indicating broad spectrum results” (March 28, 2022)
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Cornell Chronicle “Promising nose spray could prevent and treat COVID-19” (March 28, 2022)
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CTV News “Chemical in broccoli slows COVID-19 virus replication in cells, mice: study” (March 27, 2022)
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Genetic Engineering & Biotechnology News “COVID-19 Potentially Thwarted by TB Infection… at Least in Mice” (March 25, 2022)
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ScienceDaily “Tuberculosis infection protects mice from developing COVID-19” (March 24, 2022)
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News Medical Life Sciences “A novel mRNA vaccine encoding delta RBD induces high neutralizing antibody titers” (March 24, 2022)
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News Medical Life Sciences “New nanoparticle-based COVID-19 vaccine platform could target other infectious diseases” (March 23, 2022)
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Northwestern Now “Nanoparticle-based COVID-19 vaccine could target future infectious diseases” (March 22, 2022)
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News Medical Life Sciences “Study discovers potent and selective human monoclonal antibodies against Omicron variant of SARS-CoV-2” (March 23, 2022)
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Genetic Engineering & Biotechnology News “Oral Formulation of Remdesivir Protective against SARS-CoV-2 in Mice” (March 23, 2022)
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ScienceDaily “Study shows effectiveness of pill form of remdesivir to treat COVID-19 in mice” (March 22, 2022)
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Laboratory Equipment “Inhalable ‘Aerogel’ Triggers Immunity to COVID-19 in Mice” (March 21, 2022)
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SciTechDaily “New BioAge Drug Prevents Death From COVID-19 in Old Mice by Reversing Immune Aging” (March 21, 2022)
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MedicalXpress “Oral drug prevents death from COVID-19 in old mice by reversing immune aging” (March 21, 2022)
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News Medical Life Sciences “Oral drug that reverses immune aging effectively prevents death in COVID-19 mouse model” (March 21, 2022)
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BioSpace “Nature Paper: BioAge’s Oral Drug Targeting the Aging Immune System Prevents Death From COVID-19 in Aged Mice” (March 21, 2022)
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The Hill “AstraZeneca says COVID-19 drug neutralizes omicron variants” (March 21, 2022)
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Genetic Engineering & Biotechnology News “COVID-19 Drug Targets Immune Aging, Enters Phase II” (March 21, 2022)
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University of Alabama News “Preclinical demonstration of a potent, universal coronavirus monoclonal antibody therapy for all COVID-19 variants” (March 18, 2022)
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Penn Today “From a pandemic, scientific insights poised to impact more than just COVID-19” (March 18, 2022)
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EurekAlert! “Excess neuropeptides disrupt lung function in infant disease and COVID-19” (March 17, 2022)
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News Medical Life Sciences “Researchers receive grant to find answers to taste loss in COVID patients” (March 15, 2022)
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EurekAlert! “Scientists look for answers to taste loss with COVID” (March 15, 2022)
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News Medical Life Sciences “Study explores neutralization of SARS-CoV-2 Omicron variant by subunit vaccine boosters” (March 14, 2022)
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ScienceDaily "New strategy for COVID-19 prophylaxis" (March 8, 2022)
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News Medical Life Sciences “Thermostable next-generation vaccine candidate against SARS-CoV-2 variants of concern studied in mice” (March 8, 2022)
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BioSpace “Angiotensin Therapeutics Inc. announces publication of a study using a soluble ACE2 protein designed for COVID-19” (March 8, 2022)
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EurekAlert! “New strategy for COVID-19 prophylaxis: Researchers of the Cluster of Excellence ImmunoSensation2 at the University of Bonn specifically stimulate the RNA receptor RIG-I” (March 8, 2022)
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News Medical Life Sciences “Omicron-specific mRNA vaccine generates immune responses in mice, hamsters and Macaques” (March 6, 2022)
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News Medical Life Sciences “Angiotensin-converting enzyme 2-based mutant decoy effectively reduces COVID-19 in mice” (March 3, 2022)
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China Global Television Network “Chinese mRNA COVID-19 antibody shields mice long-term” (March 3, 2022)
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News Medical Life Sciences “Peptide-based vaccine fails to protect mice against SARS-CoV-2 despite T cell response” (February 28, 2022)
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News Medical Life Sciences “Mouse-adapted virus model to study persistent COVID induced lung disease” (February 21, 2022)
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News Medical Life Sciences “Study suggests non-classical inhibition of TBK1/IKKepsilon is protective against severe COVID-19 immunopathology in vivo” (February 21, 2022)
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The Weather Channel “Rogue Antibodies Responsible for Inflammation and Clotting in Severe COVID-19 Patients: Study” (February 21, 2022)
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The Jerusalem Post “Experimental BioVaxys COVID-19 vaccine may eliminate risk of myocarditis” (February 20, 2022)
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News Medical Life Sciences “Study reports a highly attenuated SARS-CoV-2 that could serve as a live-attenuated vaccine platform” (February 18, 2022)
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News Medical Life Sciences “Study examines lyophilized mRNA-lipid nanoparticle vaccines with long-term stability” (February 16, 2022)
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The Asahi Shimbun “Cell aging likely cause of lingering COVID-19 aftereffects” (February 16, 2022)
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Yale School of Medicine “HHMI Gives Major Support to Yale COVID-19 Research” (February 15, 2022)
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UPI.com Health News “Inhaled COVID-19 vaccine could offer benefits over shots” (February 15, 2022)
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News Medical Life Sciences “Variations in the neutralization of SARS-CoV-2 variants in vaccinated mice and primates” (February 14, 2022)
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EurekAlert! “Study shows new drug combination more effective against SARS-CoV-2” (February 14, 2022)
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News Medical Life Sciences “Study describes a beta-CoV spike protein target for protective antibodies that may facilitate pan-beta-CoV vaccine development” (February 14, 2022)
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Yale Daily News “New nasal vaccine could provide protection against COVID-19 infection, Yale study suggests” (February 11, 2022)
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The New Yorker “Did Omicron come from mice?” (February 10, 2022)
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Washington University School of Medicine in St. Louis News “Researchers unravel omicron’s secrets to better understand COVID-19” (February 9, 2022)
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The Daily Iowan “UI research shows omicron variant causes weak disease in mice, hamsters” (February 9, 2022)
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Howard Hughes Medical Institute News “Nasal Spray Booster Keeps COVID-19 at Bay” (February 8, 2022)
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News Medical Life Sciences “Efficacy of MVA-CoV2-S vaccination to prevent SARS-CoV-2 cerebral infection and associated damage” (February 8, 2022)
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South China Morning Post “Did Omicron jump from mice to men? Chinese scientists say it’s possible” (February 4, 2022)
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AZoNano.com “Novel Nanoarray SARS-CoV-2 Vaccine Helps Protect Immunocompromised” (February 4, 2022)
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News Medical Life Sciences “Researchers develop influenza virus-like particle-based hybrid vaccine for both influenza and SARS-CoV-2 viruses” (February 4, 2022)
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Technology Networks “New COVID-19 Mouse Model Developed To Advance Research” (January 31, 2022)
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The Jerusalem Post “Could the Omicron COVID-19 variant have originated in mice? - Study” (January 31, 2022)
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The Scientist “Brain Fog Caused by Long COVID and Chemo Appear Similar” (January 28, 2022)
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News Medical Life Sciences “Early-stage alveolar epithelial cell necrosis linked to COVID-19-induced acute respiratory distress syndrome” (January 27, 2022)
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RT.com “Omicron Covid strain evolved in mice – Chinese study” (January 25, 2022)
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Outsourcing-Pharma.com “Charles River joins with immunology lab on COVID-19 research” (January 24, 2022)
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News Medical Life Sciences “Characterization of unique pathogenesis of SARS-CoV-2 Delta variant in mouse model” (January 24, 2022)
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Forbes “Even Mild Covid-19 Can Cause Brain Dysfunction And Cognitive Issues” (January 24, 2022)
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SciTechDaily “New Research Suggests High-Purity CBD May Help Block COVID-19 Virus From Replicating” (January 24, 2022)
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News Medical Life Sciences “Cannabidiol found to inhibit SARS-CoV-2 infection in human cells and mice” (January 21, 2022)
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University of Wisconsin-Madison News “Omicron causes less severe illness in animal models than previous variants” (January 21, 2022)
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Pharmacy Times “Study: Antibodies in Blood Soon After COVID-19 Onset May Predict Severity” (January 21, 2022)
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NBC Chicago “Mild COVID-19 Infections Can Lead to Long-Term Neurological Damage: Study” (January 21, 2022)
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Fierce Biotech “Decoy vesicles protect against COVID-19 from coronavirus variants in early tests” (January 20, 2022)
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Technology Networks “Decoy Protein Effective Against SARS-CoV-2 Variants in Mouse Study” (January 20, 2022)
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IFLScience “Snorting Superpower Nano Bubbles Can Protect Against COVID-19 Variants, Says Mice Study” (January 20, 2022)
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News Medical Life Sciences “Study finds Omicron infection effectively induces immunity against itself and enhances protection against other variants in vaccinated individuals” (January 20, 2022)
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The Indian Express “Study says: By itself, Omicron does not boost immunity level” (January 20, 2022)
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NBC Connecticut “Study Says People With Mild COVID-19 Symptoms Could Suffer From Long-Term Neurological Damage” (January 20, 2022)
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Georgia State University News “Researchers Find Newer Variants of SARS-CoV-2 Can Infect Mice, Unlike the Original Version of the Virus” (January 19, 2022)
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Genetic Engineering & Biotechnology News “COVID-19 Severity Predicted by Early Presence of Afucosylated Antibodies” (January 19, 2022)
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News Medical Life Sciences “An alternative mouse model of SARS-CoV-2 infection” (January 17, 2022)
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Fox News “Anti-COVID nasal spray could protect against infection for up to 8 hours” (January 12, 2022)
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MedicalNewsToday “COVID-19: Did Omicron evolve in mice?” (January 7, 2022)
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The Washington Post “Omicron could have a silver lining by boosting immunity, some experts say. But don’t bet on it” (January 7, 2022)
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Deseret News “The omicron variant may have come from mice, new study says” (January 7, 2022)
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10News.com San Diego ”In-Depth: Melatonin helps people with severe COVID recover. How about long haulers?” (January 7, 2022)
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News Medical Life Sciences “Melatonin found to inhibit SARS-CoV-2 entry into mice brains” (January 6, 2022)
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EurekAlert! “LJI and Charles River Laboratories to collaborate on COVID-19 research” (January 6, 2022)
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Nature News “Omicron’s feeble attack on the lungs could make it less dangerous” (January 5, 2022)
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Deseret News “Where omicron variant symptoms develop right now” (January 4, 2022)
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The Economic Times News “RNA-based therapy can protect from many Covid variants: Study” (January 4, 2022)
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WebMD News “Omicron Variant Appears to Cause Less Damage to Lungs, Studies Say” (January 3, 2022)
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The Guardian “New studies reinforce belief that Omicron is less likely to damage lungs” (January 2, 2022)
2021 News
- The New York Times “Studies Suggest Why Omicron Is Less Severe: It Spares the Lungs” (December 31, 2021)
- News Medical Life Sciences “Less severe clinical consequences of infection with SARS-CoV-2 Omicron variant” (December 31, 2021)
- ABC News Australia “As Omicron COVID cases continue to surge, the race is on to find a variant-proof vaccine” (December 27, 2021)
- Western University News “Novel approach to COVID-19 vaccine shows early promise” (December 20, 2021)
- News Medical Life Sciences “Humanized mice reveals why few COVID-19 cases are more severe than others” (December 20, 2021)
- News Medical Life Sciences “Efficacy of SARS-CoV2 variant-specific replicating RNA vaccines on SARS-CoV-2 variants of concern” (December 19, 2021)
- DocWire News “A humanized mouse model of chronic COVID-19” (December 18, 2021)
- YaleNews “Why are some COVID cases more severe? ‘Humanized’ mice offer a clue” (December 17, 2021)
- NewScientist “How did the omicron coronavirus variant evolve to be so dangerous?” (December 17, 2021)
- News Medical Life Sciences “MV130 immunotherapy boosts natural and vaccine-induced SARS-CoV-2 immunity in mice” (December 13, 2021)
- GlobeNewswire.com “Inotiv, Inc. Announces the Launch of New Genetically Engineered Rodent Models for SARS-CoV-2 (COVID-19) Research” (December 13, 2021)
- News Medical Life Sciences “Nasal infection drives lethal lung injury due to SARS-CoV-2 in mice” (December 12, 2021)
- News Medical Life Sciences “Immunogenicity and safety of COVID-19 subunit vaccine Nanocovax in animal models” (December 9, 2021)
- PBS NewsHour “Some experts suggest omicron variant may have evolved in an animal host” (December 8, 2021)
- News Medical Life Sciences “SARS-CoV-2 S2 immunization as a pan-coronavirus vaccine approach” (December 6, 2021)
- Technology Networks “Telomere Damage May Increase SARS-CoV-2 Susceptibility” (December 3, 2021)
- ScienceDaily “Damaged telomeres in the elderly may increase susceptibility to SARS-CoV-2” (December 2, 2021)
- EurekaAlert! “Damaged telomeres in the elderly may increase susceptibility to SARS-CoV-2” (December 2, 2021)
- Technology Networks “How To Freeze-Dry a Potential COVID-19 Vaccine” (December 2, 2021)
- EurekaAlert! “Study: How to freeze-dry a potential COVID-19 vaccine” (December 1, 2021)
- GlobeNewswire.com “Cocrystal Pharma Presents Preclinical Data from COVID-19 Antiviral Programs and Outlines Near-Term Clinical Plans at the World Antiviral Congress 2021” (December 1, 2021)
- News Medical Life Sciences “Northwestern researchers continue to tackle every facet of COVID-19 pandemic” (November 30, 2021)
- OregonLive.com “Safe, low-cost antidepressant pill prevents COVID-19 patients from developing severe symptoms, studies show” (November 30, 2021)
- News Medical Life Sciences “Extended host range for SARS-CoV-2 variants of concern” (November 29, 2021)
- News Medical Life Sciences “Efficacy and safety of an RBD-based recombinant protein COVID-19 vaccine” (November 26, 2021)
- SciTechDaily “COVID-19 Can Infect Nerve Cells and Cause a Range of Neurological and Psychiatric Symptoms” (November 26, 2021)
- PR Newswire “Biotron Drug Effective Against COVID-19 In Animals” (November 25, 2021)
- News Medical Life Sciences “Tobacco mosaic virus nanoparticle-based novel COVID-19 vaccine candidate” (November 23, 2021)
- Forbes “Stimulating Innate Immunity Stops SARS-CoV-2 Infection” (November 17, 2021)
- News Medical Life Sciences “Potential COVID-19 nasal spray vaccine shows promise in mice” (November 15, 2021)
- Chapelboro.com “UNC, Duke Scientists Identify New Antibody To Fight COVID-19 and Its Variants” (November 15, 2021)
- News Medical Life Sciences “Mycobacterium tuberculosis may induce resistance to secondary SARS-CoV-2 infection” (November 14, 2021)
- Stanford Medicine News “COVID-19 nasal spray vaccine in the works at Stanford Medicine” (November 11, 2021)
- News Medical Life Sciences “Phage-like particle system provides a platform for quick and easy vaccine generation” (November 11, 2021)
- News18.com “New RNA-based Therapy Protects Mice from Coronavirus, Variants Including Delta: Study” (November 11, 2021)
- YaleNews “Immune system early responder can combat COVID-19” (November 10, 2021)
- EurekAlert! “Yale researchers develop RNA-based therapy that clears SARS-CoV-2 from mice” (November 10, 2021)
- University of Miami News “Researchers develop a ‘net’ to prevent the coronavirus from entering cells” (November 10, 2021)
- DailyMail.com “Scientists discover an antibody that can protect people against several coronaviruses including COVID-19 and its variants” (November 9, 2021)
- The Jerusalem Post “COVID: Scientists find super-antibody that might help fight new variants” (November 9, 2021)
- Brown University News “Study offers insights on why the elderly are more susceptible to COVID-19” (November 8, 2021)
- News Medical Life Sciences “Rapid antibody response induced by mRNA COVID vaccines in mice” (November 7, 2021)
- Genetic Engineering & Biotechnology News “Cross-Reactive Antibody Blocks Infections against Multiple Coronaviruses in Mice” (November 4, 2021)
- ScienceDaily “Scientists identify new antibody for COVID-19 and variants” (November 2, 2021)
- 24-7pressrelease.com “An Oral Drug from Holy basil (Tulsi) is Effective Against COVID-19 Symptoms in Lab Study” (November 2, 2021)
- SciTechDaily “Needle-Free COVID-19 Vaccine Shows Promise – Protection via a Single Pain-Free Click” (October 30, 2021)
- Fierce Biotech “A COVID-19 vaccine delivered with a patch rivals traditional shots in mice: study” (October 29, 2021)
- SciTechDaily “COVID Vaccine Dosing ‘Mistake’ Leads to Surprising Discovery” (October 26, 2021)
- News Medical Life Sciences “Blood pressure drug increases SARS-CoV-2 receptors in transmission and pathogenesis associated tissues” (October 25, 2021)
- News.northwestern.edu “AstraZeneca’s vaccine dosing ‘mistake’ led to new dosage finding in mice” (October 25, 2021)
- EurekaAlert! “AstraZeneca’s vaccine dosing ‘mistake’ led to new dosage finding in mice” (October 25, 2021)
- Washington University School of Medicine in St. Louis News “Antiviral compound blocks SARS-CoV-2 from entering cells” (October 11, 2021)
- Fierce Biotech “Novel vaccine strategy protects mice from COVID-19 and 4 related coronaviruses (October 8, 2021)
- EurekaAlert! “Researchers demonstrate vaccination approach in mice that could prevent future coronavirus outbreaks” (October 8, 2021)
- SciTechDaily “New Vaccination Strategy Developed That Could Prevent Future Coronavirus Outbreaks” (October 8, 2021)
- Indiana University School of Medicine Blogs “IU researchers study long-term effects of COVID-19 on bone growth” (October 4, 2021)
- Advanced Science News “Biomaterial-based COVID-19 vaccine shows adaptive immunity in mice” (October 4, 2021)
- European Pharmaceutical Review “Temperature stable microneedle patch successfully delivers DNA COVID-19 vaccine” (September 23, 2021)
- Technology Networks “Microneedle Patch Delivers COVID-19 Vaccine” (September 23, 2021)
- News Medical Life Sciences “Dynamics of innate immune responses decide COVID-19 severity in genetically diverse mice” (September 21, 2021)
- JAX News “Host genetic backgrounds underlie variable COVID-19 pathology” (September 20, 2021)
- The Hill “No-fridge coronavirus vaccine looks promising: study” (September 15, 2021)
- MedicalNewsToday “COVID-19: Experimental vaccine lasts 1 month at room temperature” (September 14, 2021)
- ConnexionFrance.com “Promising results in trials of French Covid nasal spray vaccine” (September 10, 2021)
- News Medical Life Sciences “Virus-like nanoparticle vaccine effective against SARS-CoV-2 in animal model” (September 10, 2021)
- National Institute on Aging News “Senolytics show potential to protect against coronavirus in older mice” (September 9, 2021)
- Technology Networks “Virus-Like Particle Vaccine Protects Animals Against COVID-19” (September 9, 2021)
- Technology Networks “Developing Nanobodies and Antibodies Against SARS-CoV-2” (September 8, 2021)
- University of Minnesota News “U of M scientists develop a novel virus-like particle COVID-19 candidate vaccine” (September 8, 2021)
- UC San Diego News Center “These Fridge-Free COVID-19 Vaccines Are Grown in Plants and Bacteria” (September 7, 2021)
- Advanced Science News “Fridge-free COVID-19 vaccine candidates offer hope to billions” (September 7, 2021)
- SciTechDaily.com “Viruses From Plants/Bacteria Key Ingredient for New COVID-19 Vaccine Candidates” (September 7, 2021)
- University of Michigan Health Lab “Why Do People with Diabetes Develop Severe COVID-19?” (September 7, 2021)
- YaleNews “In the immune arsenal, antibodies offer best long-term hope against COVID” (September 2, 2021)
- News Medical Life Sciences “Study shows bacille Calmette-Guérin vaccine can protect mice against lethal SARS-CoV-2 challenge” (September 1, 2021)
- SciTechDaily “Antibody-Disease Enhancement (ADE) of COVID-19 Does Not Appear To Occur in Animal Models” (August 31, 2021)
- Yahoo! Finance “Oragenics’ SARS-CoV-2 Spike Protein Produces Neutralizing Antibodies in Mice with Intramuscular and Intranasal Adjuvants” (August 30, 2021)
- News Medical Life Sciences “The influence of COVID-19 on platelet activation and aggregation” (August 26, 2021)
- SciTechDaily.com “Antibody Discovered That Protects Against Broad Range of COVID-19 Virus Variants” (August 23, 2021)
- Washington University School of Medicine in St. Louis News “Antibody protects against broad range of COVID-19 virus variants” (August 20, 2021)
- Times of India “Covid-19: Alpha, Beta, Gamma variants infect mice; Delta may not” (August 19, 2021)
- News.northwestern.edu “2.0 of COVID-19 vaccine quickly kicks immune system into high gear” (August 18, 2021)
- YaleNews “Videos capture lethal progress of COVID-19 virus” (August 18, 2021)
- ScienceDaily “A COVID-19 vaccine strategy to give the body border protection” (August 11, 2021)
- News Medical Life Sciences “SARS-CoV-2 variants and their ability to infect mice” (August 10, 2021)
- News Medical Life Sciences “Study shows efficacy of gamma irradiation of SARS-CoV-2 vaccine candidate in mouse model” (August 10, 2021)
- Drug Target Review “Masitinib found to be an effective COVID-19 treatment in mouse model” (August 3, 2021)
- Genetic Engineering & Biotechnology News "Potential COVID-19 Treatment, Masitinib Inhibits SARS-CoV-2 Replication in Mice" (July 22, 2021)
- News Medical Life Sciences “Next-generation COVID-19 vaccine provides robust immunity against SARS-CoV-2 in mice” (July 20, 2021)
- News Medical Life Sciences “New OMV-based COVID-19 vaccine candidate proves effective in mice” (July 14, 2021)
- HealthDay News “Inhaled COVID Vaccine Shows Promise in Animal Trials” (July 13, 2021)
- SciTechDaily “Virologists Demonstrate Successful Treatment for SARS-CoV-2, the Virus That Causes COVID-19” (July 13, 2021)
- The Hill “New one-dose COVID-19 vaccine that can be inhaled tested in animals” (July 12, 2021)
- Fox News “Inhaled COVID-19 vaccine successful in animal study” (July 9, 2021)
- ScienceDaily “Inhaled COVID-19 vaccine prevents disease and transmission in animals” (July 8, 2021)
- India News “Scientists identify post-infection treatment for Covid-19” (July 5, 2021)
- The Jerusalem Post “COVID-19: Could vaping make the virus more infectious? - study” (July 2, 2021)
- Yahoo! News “Vaping Increases Your Chances of Catching Covid-19, Finds New Study” (July 1, 2021)
- Newswise “Vaping Increases Susceptibility to Coronavirus in Mice” (June 29, 2021)
- The Scientist “The Quest for a Universal Coronavirus Vaccine” (June 29, 2021)
- Chemical & Engineering News “The antivirals that weren’t: drug repurposing for COVID-19 produced misleading results” (June 29, 2021)
- The Science Times “COVID-19 Virus Being Copied and Trapped, 'Nanodecoy' Cells Produced by Human Lungs” (June 25, 2021)
- SciTechDaily “Nanodecoys – Made From Human Lung Spheroid Cells – Bind and Neutralize SARS-CoV-2 (COVID-19) Virus” (June 24, 2021)
- Howard Hughes Medical Institute News “Universal Vaccine Could Protect Against Future Coronaviruses” (June 23, 2021)
- Drug Target Review “Novel vaccine against coronaviruses protects mice from infection” (June 23, 2021)
- Genetic Engineering & Biotechnology News “SARS-CoV-2 Variants May Succumb to Multivalent Nanobodies” (June 22, 2021)
- WRAL TechWire.com “UNC researchers develop potential universal coronavirus vaccine” (June 22, 2021)
- Channel News Asia “Dual-antibody drugs effective against COVID-19 variants in animal study” (June 22, 2021)
- ScienceDaily “Antibody disease enhancement of COVID-19 does not appear to occur in animal models” (June 21, 2021)
- Washington University School of Medicine in St. Louis News “COVID-19 dual-antibody therapies effective against variants in animal study” (June 21, 2021)
- MedicalXpress “Vaccination, previous infection, protect against SARS-CoV-2 gamma variant in animal model” (June 18, 2021)
- News Medical Life Sciences “Mouse-adapted SARS-CoV-2 and simian adenovirus vector advance COVID-19 vaccine research” (June 17, 2021)
- Drug Target Review “Stem cells may be key for new vaccines against COVID-19” (June 17, 2021)
- News18.com “Covid-19 May Reactivate Dormant Tuberculosis in Patients, Finds Study” (June 17, 2021)
- News Medical Life Sciences “Could urine tests predict kidney injury and mortality in COVID-19?” (June 15, 2021)
- NIH Director’s Blog “Could a Nasal Spray of Designer Antibodies Help to Beat COVID-19?” (June 15, 2021)
- Genetic Engineering & Biotechnology News “Novavax Plans FDA Filing for COVID-19 Vaccine after Positive Efficacy Data” (June 14, 2021)
- UMassMedNews “UMMS research identifies potential antiviral compound for COVID-19, flu, other viral infection” (June 11, 2021)
- News Medical Life Sciences “Could the COVID-19 vaccination rollout protect against future coronavirus outbreaks?” (June 10, 2021)
- Drug Target Review “Senolytic drugs reduce COVID-19 symptoms in mice, study shows” (June 9, 2021)
- The Week “Nasal spray antibody treatment shows promise against COVID-19, variants in mouse study” (June 9, 2021)
- Genetic Engineering & Biotechnology News “COVID-19’s Toll on the Elderly May Be Halted by Targeting Cell Senescence” (June 9, 2021)
- MedicalXpress “Common diabetes drug shows promise as treatment for COVID-19 lung inflammation” (June 9, 2021)
- Reuters “New antibody drug shows promise in mouse study; vaping may increase lung vulnerability to virus” (June 8, 2021)
- ScienceDaily “Preclinical study suggests new approach to reduce COVID-19 death among the elderly” (June 8, 2021)
- News Medical Life Sciences “New vaccine candidate with RBD and N protein targets protects against SARS-CoV-2 in preclinical trials” (June 2, 2021)
- Business Standard “Drug that blocks multiple coronavirus variants in mice identified” (May 31, 2021)
- News-Medical.Net “New drug effectively prevents severe COVID-19 in mice infected with SARS-CoV-2” (May 29, 2021)
- MedicalNewsToday “COVID-19 DNA vaccine candidates show promise in hamsters, mice” (May 29, 2021)
- CTV News “U.S. researchers find drug blocks severe COVID-19 symptoms in mice, including variants” (May 29, 2021)
- ScienceDaily “Researchers discover drug that blocks multiple SARS-CoV-2 variants in mice” (May 28, 2021)
- EconomicTimes “New DNA vaccine for COVID-19 effective in mice, hamsters: Study” (May 28, 2021)
- EurekAlert! “DNA vaccines for COVID-19 effective in mice, hamsters” (May 27, 2021)
- NewsGP “Potential COVID treatment reduces viral count in mice lungs by 99.9%” (May 20, 2021)
- Nature.com News “Mice with severe COVID symptoms could speed vaccine effort” (May 11, 2021)
- Business Today “New COVID-19 vaccine protects monkeys, mice from coronavirus” (May 11, 2021)
- Drug Discovery World-online.com “Taconic biosciences launches new Covid-19 mouse model” (May 7, 2021)
- News-Medical.Net “Researchers develop a multivalent vaccine for COVID-19 and influenza” (May 6, 2021)
- The Chicago Maroon “UChicago Researchers Develop Novel “Nanotrap” COVID-19 Treatment” (May 6, 2021)
- MIT Technology Review “Why mixing vaccines could help boost immunity” (May 6, 2021)
- Nature.com “COVID research: a year of scientific milestones” (May 5, 2021)
- News-Medical.Net “Pan-COVID-19 vaccine protects mice against SARS-CoV-2 variants” (May 5, 2021)
- News-Medical.Net “Vaccine candidate targeting SARS-CoV-2 nucleocapsid protein elicits protective immune response in animal model” (May 4, 2021)
- News-Medical.Net “Study reveals new broadly neutralizing and protective antibody against coronaviruses” (May 3, 2021)
- News-Medical.Net “Live "attenuated" influenza virus vaccine protects animals against respiratory infections, including SARS-CoV-2” (May 2, 2021)
- SciTechDaily.com “SARS-CoV-2 Spike Protein Alone May Cause COVID-19 Lung Damage – Even Without the Presence of Intact Virus” (April 30, 2021)
- MedicalXpress “SARS-CoV-2 spike protein alone may cause lung damage” (April 27, 2021)
- News-Medical.Net “Interfering RNA nanoparticles could be a potential COVID-19 therapy” (April 21, 2021)
- Medicine.wustl.edu “Podcast: A year later, scientists recall efforts to jump-start research into mysterious new coronavirus” (April 21, 2021)
- News-Medical.Net “Characterization of lab-produced neutralizing antibodies targeting SARS-CoV-2” (April 21, 2021)
- News-Medical.Net “Study identifies how SARS-CoV-2 enters and infects the brain” (April 21, 2021)
- Reuters “COVID SCIENCE-Moderna vaccines promising vs variants in mouse study; no higher risk for poor outcomes found with UK variant” (April 14, 2021)
- News-Medical.Net “Experimental evidence that ADAM17 inhibition prevents severe COVID-19” (April 13, 2021)
- NationalGeographic.com “Microbes in your gut may be new recruits in the fight against viruses” (April 13, 2021)
- News-Medical.Net “New mRNA COVID-19 vaccine candidate shows promise in vivo” (March 31, 2021)
- New York Times Virus Variants Can Infect Mice, Scientists Report (March 31, 2021)
- Forbes “From Cats And Dogs To Minks And Mice, Covid-19 Variants Are Infecting The Ecosystem” (March 26, 2021)
- WebMD “COVID Variants Detected in Animals, May Find Hosts in Mice” (March 25, 2021)
- News-Medical.Net “Neutralizing antibodies to SARS-CoV-2 in mice depend on Fc effector function” (March 24, 2021)
- Fierce Biotech “CureVac’s COVID-19 mRNA vaccine protects mice against aggressive coronavirus variant” (March 24, 2021)
- News-Medical.Net “A new COVID-19 candidate vaccine induces robust humoral and cellular immune responses in mice” (March 23, 2021)
- Reuters “No virus variants can evade all antibody types, so far; new variants can infect mice” (March 19, 2021)
- Global News “COVID-19: No variants can escape human antibodies yet, though some can infect mice” (March 19, 2021)
- News-Medical.Net “Novel protein construct prevents lethal COVID-19 in mice” (March 16, 2021)
- China Global Television Network Influenza virus can promote COVID-19 infection in cells, mice: study (February 21, 2021)
- News Medical Life Sciences SARS-CoV-2 DNA vaccine tested in animal model (February 21, 2021)
- News Medical Life Sciences New mouse model of SARS-CoV-2 infection reflects features of human infection (February 14, 2021)
- MedicalNewsToday “COVID-19: Antiviral prevents and treats infection in lab tests” (February 12, 2021)
- New York Times Could a Single Vaccine Work Against All Coronaviruses? (February 9, 2021)
- University of Maryland Baltimore News "Novavax Vaccine Demonstrates Strong Immune Response" (February 9, 2021)
- Karolinska Institutet News "COVID-19 vaccine from new vaccine platform effective in mice" (February 4, 2021)
- News-Medical.Net "Emory MVA COVID-19 vaccine proven safe and effective in mice and monkeys" (February 4, 2021)
- Mount Desert Islander "Mouse research aids COVID-19 response" (January 29, 2021)
- Yahoo News "Researchers found far higher levels of coronavirus in the brains of mice than the lungs - a possible explanation for neurological symptoms" (January 28, 2021)
- EurekAlert "NSAIDs might exacerbate or suppress COVID-19 depending on timing, mouse study suggests" (January 22, 2021)
- Science Daily "Study finds COVID-19 attack on brain, not lungs, triggers severe disease in mice" (January 19, 2021)
- News-Medical.Net "Modified Vaccinia Ankara model vaccine prevents COVID-19 in transgenic mice study" (January 6, 2021)
2020 News
- The Science Times "Inhaled vaccines show effectiveness in strengthening immune response in mice, primates" (December 11, 2020)
- MedicalXpress "Scientists discover how COVID-19 virus causes multiple organ failure in mice" (December 8, 2020)
- TexasStandard "Meet the lab mice helping scientists find a COVID-19 vaccine" (December 7, 2020)
- FIERCE Biotech "COVID-19 vaccines based on novel platforms show early promise in mice" (December 3, 2020)
- LaboratoryEquipment.com "Repurposed mouse model sheds light on loss of smell in COVID-19 patients" (December 2, 2020)
- Drug Target Review "COVID-19 vaccine candidate is 96.4 percent effective in mice, study shows" (December 1, 2020)
- Medicine at Michigan "Making a new mouse could transform COVID-19 research" (Autumn 2020)
- News-Medical.Net "Transgenic mouse model could recapitulate severe COVID-19 in humans" (November 26, 2020)
- FIERCE Biotech "Adagio's COVID-19 antibody protects mice and zaps related viruses in lab tests" (November 20, 2020)
- News-Medical.Net "Promising yeast-expressed SARS-CoV-2 vaccine candidate effective in mice" (November 9, 2020)
- The Scientist "The many model systems of COVID-19" (November 4, 2020)
- Genetic Engineering & Biotechnology News "COVID-19 nanoparticle vaccine elicits high levels of protective antibodies in mice" (November 3, 2020)
- ScienceNews "How two immune system chemicals may trigger COVID-19’s deadly cytokine storms" (October 30, 2020)
- GlobeNewsWire "Global mice model market report 2020-2025: impact of COVID-19 - increasing demand for humanized mice models" (October 19, 2020)
- News-Medical.Net "Obesity changes ACE2 and TMPRSS2 expression in mice: Implications for COVID-19" (October 18, 2020)
- News-Medical.Net "Nasal spray COVID-19 vaccine shows promising results in mice" (October 12, 2020)
- News-Medical.Net "Keto diet could be beneficial for elderly COVID-19 patients" (September 14, 2020)
- LIVE SCIENCE "The new coronavirus can infect brain cells, study finds" (September 13, 2020)
- TheWeek News India "NII's potential COVID-19 vaccine shows encouraging results in study on mice" (September 12, 2020)
- The New York Times "How the coronavirus attacks the brain" (September 9, 2020)
- bneINTELLINEWS "Slovenian researchers develop coronavirus vaccine effective in mice" (September 1, 2020)
- ScienceDaily "Mouse-adapted SARS-CoV-2 model provides new tool for COVID-19 discoveries" (August 31, 2020)
- The Science Advisory Board "New mouse-adapted models helps accelerate COVID-19 vaccines, therapies" (August 28, 2020)
- Washington University School of Medicine in St. Louis News "Nasal vaccine against COVID-19 prevents infection in mice" (August 21, 2020)
- Washington University School of Medicine in St. Louis News "Experimental COVID-19 vaccine prevents severe disease in mice" (August 11, 2020)
- The New York Times Magazine "How covid sends some bodies to war with themselves" (August 11, 2020)
- The New Yorker "Can designer mice save us from COVID-19?" (August 10, 2020)
- The Daily Iowan "University of Iowa researchers develop mice model to study COVID-19 symptoms" (June 28, 2020)
- Drug Target Review "Method to convert any mouse into COVID-19 model made available to researchers" (June 22, 2020)
- MedicalXpress "Off-the-shelf tool for making mouse models of COVID-19" (June 16, 2020)
- Study Finds "COVID-19 mouse model may hold key to new treatments, understanding risk factors" (June 13, 2020)
- The Economist "An animal model of COVID-19 is now available" (June 11, 2020)
- MedicalXpress "COVID-19 mouse model will speed search for drugs, vaccines" (June 10, 2020)
- Arizona Republic "Mice can't catch COVID-19, so a UA lab is making new kind of mouse" (June 10, 2020)
- Nordic Life Science News "A vaccine against COVID-19, developed by researchers from the Univ. of Copenhagen, has been tested in mice and shows promising results" (June 10, 2020)
- HospiMedica "Transgenic mouse that models immune disease's cytokine storms could point to treatment solution for COVID-19" (June 5, 2020)
- RegMedNet "COVID-19 treatment breakthrough using fibroblast cell therapy in mice" (June 1, 2020)
- SciTechDaily "New research points to treatment for COVID-19 cytokine storms, solution to global pandemic" (May 31, 2020)
- Taconic "An overview of mouse models for COVID-19" (May 30, 2020)
- Times Now "Coronavirus: Mouse model mimics COVID-19 infection in humans, may help test drugs" (May 28, 2020)
- News-Medical.Net "Transgenic mouse model of HLH may play key role in saving lives during COVID-19" (May 28, 2020)
- ScienceDaily "HLH research points to treatment for COVID-19 cytokine storms" (May 28, 2020)
- Genetic Engineering & Biotechnology News "COVID-19 mouse CRISPR engineered to recapitulate human COVID-19" (May 27, 2020)
- WHYY PBS "The great research mouse rescue amid the pandemic" (May 15, 2020)
- Scientific American "From Hamsters to Baboons: The Animals Helping Scientists Understand the Coronavirus" (May 14, 2020)
- Knowable Magazine, "Building a mouse squad against Covid-19" (May 14, 2020)
- Emerging Microbes & Infections "Animal models for emerging coronavirus: progress and new insights" (May 13, 2020)
- Technology Networks "Mouse Study Explores Why COVID-19 Patients Can Lose Their Sense of Smell" (May 13, 2020)
- LabAnimal "Mobilizing animal models against a pandemic" (May 12, 2020)
- EurekAlert "Russia creates its own humanized mice to test COVID-19 vaccines and drugs" (May 4, 2020)
- NIH News "Microneedle coronavirus vaccine triggers immune response in mice." (April 14, 2020)
- Science, "Mice, hamsters, ferrets, monkeys. Which lab animals can help defeat the new coronavirus?" (April 13, 2020)
- Advanced Science News, "Mouse study shows engineered virus could block coronavirus infections" (April 8, 2020)
- Technology Networks "Antiviral against COVID-19 reduces damage in mouse lungs" (April 7, 2020)
- Scientific American, "New coronavirus drug shows promise in animal tests" (April 7, 2020)
- The Hill, "First peer-reviewed coronavirus vaccine shows promise in mice" (April 2, 2020)
- Science, "'It’s heartbreaking.' Labs are euthanizing thousands of mice in response to coronavirus pandemic" (Mar. 23, 2020)
- Bangor Daily News, "Maine lab starts breeding mice for coronavirus vaccine" (March 18, 2020)
- National Public Radio (NPR) "Mouse Hunt: Lab Races to Grow Mice for COVID-19 Research." (March 14, 2020)
- The New York Times, "These lab animals will help fight coronavirus" (March 14, 2020)
- STAT News, "Researchers rush to test coronavirus vaccine in people without knowing how well it works in animals" (March 11, 2020)
- Bloomberg, "A Virus Cure Depends on Rare Lab Mice, But There Aren’t Enough" (March 11, 2020)
- Nature, "Labs rush to study coronavirus in transgenic animals – some are in short supply" (March 9, 2020)
- STAT News, "From ferrets to mice and marmosets, labs scramble to find right animals for coronavirus studies" (March 5, 2020)