Researches regulation of stem cells in the blood in normal development, aging and leukemia transformation.
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Researches regulation of stem cells in the blood in normal development, aging and leukemia transformation.
The Trowbridge laboratory researches the development and maintenance of hematopoietic stem cells (HSCs), as well as alterations that occur during normal aging and during transformation to leukemic cells. Our current focus is on the epigenetic regulation of these processes, with the goal of identifying biomarkers of disease that can be targeted for new therapies.