Jackson Laboratory

Resource Development and Dissemination

Our Research Focus

Mice are the leading model organisms used for biomedical research. We obtain our mouse models for human disease in several ways, including selecting spontaneous mutants showing disease symptoms, engineering specific mutations, and acquiring models generated by other researchers. We also actively gather, assess and distribute models generated by researchers investigating particular diseases to ensure high quality and standardization.

Faculty & Staff

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Lab Staff

Robyn Ball, Ph.D.

Scientific Curator

Susan Bello, Ph.D.

Research Scientist

David E. Bergstrom, Ph.D.

Research Scientist

Molly Bogue, Ph.D.

Lab Staff

Morgan Brady, Ph.D.

Senior Research Scientist

Bo Chang, Ph.D.

Professor

Elissa J. Chesler, Ph.D.

Director, Research Scientist

Elise Courtois, Ph.D.

Lab Staff, Software Engineer

Matthew Gerring, MEng

Research Scientist

Vishnu Hosur, Ph.D.

Affiliated Scientist, Senior Research Scientist

James Kadin, Ph.D.

Associate Professor

Shuzhao Li, Ph.D.

Lab Staff

Hannah Megathlin

Dave Mellert, Ph.D.`

Program Manager

Jenny Morgenweck, Ph.D

Lab Staff

Chew Yee Ngan, Ph.D.

Professor

Patsy Nishina, Ph.D.

Associate Research Scientist

Jeremy Racine, Ph.D.

Associate Professor

Laura Reinholdt, Ph.D.

Lab Staff, Senior Research Scientist

Joel Richardson, Ph.D.

Associate Professor

Martin Ringwald, Ph.D.

Research Scientist

Michael Sasner, Ph.D.

Computational Scientist

Michael Saul, Ph.D.

Professor

Lenny Shultz, Ph.D.

Research Scientist

Santhosh Sivajothi, Ph.D.

Bioinformatics/Data Analyst

Grace Stafford, Ph.D.

Professor

John Sundberg, D.V.M., Ph.D., DACVP

Gregg TeHennepe, B.A.

Jarek Trapszo

Director

Aamir Zuberi, Ph.D.

Research Centers & Resources

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Mutant Mouse Resource and Research Center (MMRRC)

The Mutant Mouse Resource and Research Center (MMRRC) distributes and cryopreserves scientifically valuable, genetically engineered mouse strains and mouse ES cell lines with...

Joan Staats Library at The Jackson Laboratory

Our specialized collection areas include: genetics, inbred mice, animal health and husbandry, development, embryology, complex traits, immunology, cancer, molecular biology,...

Biology of Beta Cell Consortium

NOD-scid IL2rgnull (NSG) and NOD-Rag1null IL2rgnull (NRG) mice support heightened levels of engraftment with human cells and tissues. These engrafted mice allow research on...

Gene Ontology Consortium

The Gene Ontology (GO) project is a collaborative effort to address the need for consistent descriptions of gene products across databases.

Mouse Resource for Craniofacial Research

This resource provides mouse models for facial, dental, eye, ear and skull development research, as well as mouse models of human craniofacial...

Cre Portal

The Cre Portal contains curated data about all recombinase-containing transgenes and knock-ins developed in mice to provide a comprehensive resource delineating known...

Parkinson's Disease Mouse Model Resource

The Parkinson’s Disease Mouse Model Resource characterizes and distributes new mouse models of Parkinsonism and Parkinson’s disease.

Eye Mutant Resource

Describes mouse models for ocular research available at The Jackson Laboratory and provides a list of known mouse mutations that affect vision.

Genetic Resource Science

Genetic Resource Science initiates and develops resource-generating research. Our team: identifies and implements innovative technologies for genetic research; makes and...

Mouse Genome Informatics

International database resource for the laboratory mouse, providing integrated genetic, genomic, and biological data.

International Mouse Strain Resource (IMSR)

The International Mouse Strain Resource offers users a combined catalog of worldwide mouse resources (live, cryopreserved, and embryonic stem cells), with direct access to...

Knockout Mouse Project (KOMP)

Scientists around the world are working to generate a targeted knockout mutation for every gene in the mouse genome through the Knockout Mouse...

Special Mouse Strains Resource

The SMSR maintains mice that are important tools for genetic analysis of complex diseases, including consomic strains.

Mouse Mutant Resource

Mice harboring spontaneous mutations have long been a major source for animal models of human genetic disorders, particularly mendelian diseases. The Mouse Mutant Resource...

MouseMine

MouseMine is a powerful data warehouse providing comprehensive API (application programming interface) access to MGI data, as well as a forms-based...

Optogenetics Resource

We offer a growing number of mouse lines expressing proteins that activate, inhibit or detect neuronal activity.

WORMHOLE

The WORM Human OrthoLogy Explorer is a meta-tool that uses machine learning to predict novel least diverged orthologs (LDOs) by integrating ortholog predictions from 17...

ArticleAugust 14, 2024
JAX researchers call for genetically diverse models to drive innovation in drug discovery
Diverse mouse models show promise in how we understand and treat diseases, offering a significant improvement over standardized but limited mouse and cellular models.
- Genetic Tools
- Resource Development and Dissemination
Featured ArticleJuly 09, 2024
What is genetic biomarker testing?
Genetic testing is a powerful tool in the fight against cancer, playing a crucial role in both prevention and personalized treatment. But what exactly are the different types of genetic tests, and how do they help?
Blog PostDecember 09, 2021
Studying CRS in a Diverse Population
To understand the future of these preclinical studies, we sat down with James Keck, Ph.D., who was recently recognized as a JAX President’s Innovation Fellow for his work creating mouse-based platforms to study the immune system, and evaluate new therapeutics for both safety and efficacy.
Press ReleaseOctober 21, 2021
JAX Ellsworth welcomes its 125th employee
The Jackson Laboratory has hired its 125th employee at the Charles E. Hewett Center in Ellsworth. The Center opened just three years ago to enable wider access to vital JAX mouse resources for the worldwide biomedical research community.

ArticleAugust 14, 2024
From mice to medicine - six questions with Nadia Rosenthal
How working with genetically diverse could revolutionize our understanding of human disease and treatment.
- Genetic Tools
- Resource Development and Dissemination
Blog PostDecember 05, 2023
Essential Tips for Selecting Mouse Models in Research
Whether you have a specific disease, gene, tissue, phenotype, or therapeutic in mind, there are four excellent resources to help you with model selection.
Research HighlightNovember 19, 2021
Exploring the functional genetic diversity of wild mice
Researchers are working to broaden the genetic diversity of mice used in biomedical research.
Press ReleaseSeptember 23, 2021
Innovation awarded to a ‘scientist’s scientist’
James Keck has been recognized as JAX President’s Innovation Fellow for inventions to accelerate drug development.