Retinal degeneration 7 rd7
Retinal degeneration 7 (rd7)
Light microscopy shows retinal waves, whorls and rosettes that increase and decrease concordant with retinal spots and later on-set photoreceptor degeneration. A 380-nt deletion from the coding region of a photoreceptor-specific nuclear receptor gene, Pnr, causes retinal abnormalities in rd7 mice.
|
Gene |
Mouse Chromosome |
Human Chromosome |
Retinal ONL disappear by |
Strains |
|---|---|---|---|---|
| rd7 | 9 | 15q23 | 30 | 77-2C2a-special; C57BL/6J-rd7 |