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| MODEL | JAX # | TYPE | DESCRIPTION | SOURCE | NOMENCLATURE | REFERENCE |
|---|---|---|---|---|---|---|
| hAbeta | 33013 | knock-in | humanized Abeta 1-42 | MODEL-AD | B6.Cg-Appem1Adiuj/J | PMID:38187716 |
| floxed hAbeta | 31050 | knock-in | humanized Abeta 1-42 with loxP sites flanking exon 14 | MODEL-AD | B6J(Cg)-Apptm1.1Aduci/J | |
| APP-GR | 38920 | genome replacement | 350kB human APP construct replacing mouse App | Koob | B6J.B6N-Apptm1.1(APP)Mdk/J | PMID:38343132 |
| APPSAA | 34711 | knock-in | humanized Abeta 1-42 with Swedish, Arctic and Austrian mutations | Denali Therapeutics | B6.Cg-Apptm1.1Dnli/J | PMID:35690868 |
| APPSDI | 39773 | knock-in | humanized Abeta 1-42 with Swedish, Dutch, and Iowa mutations | Sasner | B6.Cg-Appem7(hAbeta,SDI)Msasn/Msasn | |
| APPSFL | 39774 | knock-in | humanized Abeta 1-42 with Swedish, Florida, and London mutations | Sasner | B6.Cg-Appem8(hAbeta,SFL)Msasn/Msasn | |
| hAbeta-Swe-loxp-KI | 39630 | knock-in | humanized Abeta 1-42 with Swedish mutation and loxP sites flanking exon 16 | MacGregor | B6(Cg)-Appem1Aduci/J | |
| hAbeta-Swe-Ibe-loxp-KI | 39631 | knock-in | humanized Abeta 1-42 with Swedish and Iberian mutations and loxP sites flanking exon16 | MacGregor | B6(Cg)-Appem2Aduci/J |