Muscular Dystrophy Efficacy Studies

JAX performs efficacy studies on mouse models for these diseases: C57BL10.mdx and D2.mdx for DMD, dyW for CMD1A, and A/J for dysferlinopathy. Additional mouse mutants are available for studies.

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References

Ground MD, et al. 2008. Towards developing standard operating procedures for pre-clinical testing in the mdx mouse model of Duchenne muscular dystrophy. Neurobiol Dis 31:1-19 PMID: 18499465